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Pedro Morais, Joao L Vilaca, Sandro Queiros, Pieter De Meester, Werner Budts, Joao Manuel R S Tavares, Jan D'hooge
Left atrial appendage (LAA) occlusion is used to reduce the risk of thromboembolism in patients with nonvalvular atrial fibrillation, by obstructing the LAA through a percutaneously delivered device. Nonetheless, correct device sizing is complex, requiring the manual estimation of different measurements in pre-/peri-procedural images, which is tedious, time-consuming and with high inter- and intra-observer variability. In this work, a semi-automatic solution to estimate the required relevant clinical measurements is described...
March 8, 2019: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Eleonora Avenatti, G Burkhard Mackensen, Kinan Carlos El-Tallawi, Mark Reisman, Lara Gruye, Colin M Barker, Stephen H Little
OBJECTIVES: The authors sought to define the feasibility and performance of 3-dimensional (3D) vena contracta area (VCA) measurement in evaluating total residual mitral regurgitation (MR) following percutaneous edge-to-edge (E-EC) mitral valve repair. BACKGROUND: Residual MR severity after percutaneous repair is not only a determinant of procedural success, but also a major prognostic factor. To date, no single echocardiographic method has been recommended for post-procedural MR quantification, with the evaluation currently relying on a complex, multiparametric appraisal...
February 22, 2019: JACC. Cardiovascular Interventions
Esra Donmez, Ernesto E Salcedo, Robert A Quaife, Joseph M Burke, Edward A Gill, John D Carroll
BACKGROUND: The effects of edge-to-edge percutaneous mitral valve repair on the shape and size of the mitral annulus and its relation to mitral regurgitation (MR) have not been well characterized. We evaluated acute changes in mitral annular shape and dimensions, and their effect on MR severity, in patients with functional and degenerative MR following MitraClip® . METHODS: Patients that underwent MitraClip® between January 2013 and May 2016 at our institution were retrospectively reviewed...
February 22, 2019: Echocardiography
Jiwon Kim, Javid Alakbarli, Maria Chiara Palumbo, Lola X Xie, Lisa Q Rong, Nathan H Tehrani, Lillian R Brouwer, Richard B Devereux, Shing Chiu Wong, Geoffrey W Bergman, Omar K Khalique, Robert A Levine, Mark B Ratcliffe, Jonathan W Weinsaft
OBJECTIVES: To assess impact of left ventricular (LV) chamber remodeling on MitraClip (MClp) response. BACKGROUND: MitraClip is the sole percutaneous therapy approved for mitral regurgitation (MR) but response varies. LV dilation affects mitral coaptation; determinants of MClp response are uncertain. METHODS: LV and mitral geometry were quantified on pre- and post-procedure two-dimensional (2D) transthoracic echocardiography (TTE) and intra-procedural three-dimensional (3D) transesophageal echocardiography (TEE)...
February 21, 2019: Catheterization and Cardiovascular Interventions
Jin Young Kim, Young Joo Suh, Kyunghwa Han, Young Jin Kim, Byoung Wook Choi
OBJECTIVES: This meta-analysis investigated the diagnostic values of transthoracic echocardiography (TTE), 2-dimensional (2D) and 3-dimensional (3D) transesophageal echocardiography (TEE), and multidetector-row computed tomography (MDCT) in patients with suspected mechanical prosthetic valve obstruction (PVO) for detecting subprosthetic mass and differentiating its causes. BACKGROUND: Diagnostic values of advanced imaging modalities, such as MDCT and TEE, for the detection and differentiation of PVO have not been investigated...
February 11, 2019: JACC. Cardiovascular Imaging
Sandro Queirós, Pedro Morais, Wolfgang Fehske, Alexandros Papachristidis, Jens-Uwe Voigt, Jaime C Fonseca, Jan D'hooge, João L Vilaça
The assessment of aortic valve (AV) morphology is paramount for planning transcatheter AV implantation (TAVI). Nowadays, pre-TAVI sizing is routinely performed at one cardiac phase only, usually at mid-systole. Nonetheless, the AV is a dynamic structure that undergoes changes in size and shape throughout the cardiac cycle, which may be relevant for prosthesis selection. Thus, the aim of this study was to present and evaluate a novel software tool enabling the automatic sizing of the AV dynamically in three-dimensional (3D) transesophageal echocardiography (TEE) images...
January 30, 2019: International Journal of Cardiovascular Imaging
Huili Zhang, Zhengde Tang, Zhihua Han, Lefeng Zeng, Changqian Wang
Catheter-based left atrial appendage closure (LAAC) has recently become an innovative strategy for preventing embolic events in patients with nonvalvular atrial fibrillation (AF). There is limited information on optimal sizing for LAAC with the recently developed LACBES® device. The aim of the present study was to assess the role of real time-three dimensional transesophageal echocardiography (RT-3D TEE) for LACBES® device selection during LAAC. A total of 22 patients with nonvalvular AF and indications for LAAC were enrolled in the study...
February 2019: Experimental and Therapeutic Medicine
Limor Ilan Bushari, Guy S Reeder, Mackram F Eleid, Krishnaswamy Chandrasekaran, Maurice Eriquez-Sarano, Charanjit S Rihal, Joseph F Maalouf
Recent innovations and advancements in 3-dimensional (3D) echocardiography allow for better understanding of anatomic relationships and improve communication with the interventional cardiologist for guidance of catheter-based interventions. The mitral valve lends itself best for imaging with transesophageal echocardiography (TEE). Consequently, the role of 3D TEE in guiding catheter-based mitral interventions has been evolving rapidly. Although several publications have reported on the advantages and role of 3D TEE in guiding one or more of the steps involved in percutaneous mitral valve repair using the MitraClip, none offer a comprehensive and practical user-friendly guide...
January 2019: Mayo Clinic Proceedings
Andrea Colli, David Adams, Alessandro Fiocco, Nicola Pradegan, Lorenzo Longinotti, Matteo Nadali, Dimosthenis Pandis, Gino Gerosa
Transapical off-pump mitral valve repair (MVr) with NeoChord implantation has become widely applied in Europe for patients presenting with severe mitral regurgitation due to leaflet prolapse or flail. The procedure is performed under real-time 2D- and 3D-transesophageal echocardiography (TEE) for both implantation and neochordae tension adjustment allowing real-time monitoring of hemodynamic recovery. Preoperative anatomic and echocardiographic selection criteria, procedure refinement, as well as innovative ex-vivo surgical simulator training have been developed and strategically employed in the past few years, to generate a robust precision-based procedural framework with significantly enhanced operator use, patient safety and clinical outcomes...
November 2018: Annals of Cardiothoracic Surgery
Abdelaal Alsayed Alkhouly, Ali Mohammad Al-Amin, Moustafa Ibraheem Mukarrab
BACKGROUND: Percutaneous balloon mitral valvuloplasty (PBMV) can be complicated with significant mitral regurgitation (MR). We performed a pilot, prospective study to evaluate the role of three dimensional transesophageal echocardiography (3D-TEE) in the prediction of MR after PBMV through mitral valve quantification (MVQ). METHODS: Between October 2014 and October 2016, 37 patients with rheumatic, moderate-to-severe mitral stenosis, referred to the Cath lab of Bab Alshearia University hospitals for PBMV, were divided into two age and sex matched groups...
November 2018: Indian Heart Journal
Jie Kai Tee, Li Yang Ng, Hannah Yun Koh, David Tai Leong, Han Kiat Ho
Liver sinusoidal endothelial cells (LSECs) represent the permeable interface that segregates the blood compartment from the hepatic cells, regulating hepatic vascular tone and portal pressure amidst changes in the blood flow. In the presence of pathological conditions, phenotypic changes in LSECs contribute to the progression of chronic liver diseases, including the loss of endothelial permeability. Therefore, modulating LSECs offers a possible way to restore sinusoidal permeability and thereby improve hepatic recovery...
December 21, 2018: International Journal of Molecular Sciences
Flavia Ballocca, Giulia Maria Ruggeri, Andrew Roscoe, Babitha Thampinathan, Tirone Esperidiao David, Roberto M Lang, Massimiliano Meineri, Wendy Tsang
BACKGROUND: Quantitative 3D assessment of the aortic root may improve planning and success of aortic valve (AV)-sparing operations. AIMS: To use 3D transesophageal echocardiography (TEE) to assess the effect of chronic aortic dilatation on aortic root shape and aortic regurgitation (AR) severity and to examine the effects of AV-sparing operations. METHODS AND RESULTS: To determine the changes with chronic aortic dilatation, we studied 48 patients, 23 with aortic dilatation (Group 1 ≤ mild AR, n = 13; Group 2 ≥ moderate AR, n = 10) and 25 Controls...
December 16, 2018: Echocardiography
Gülay Gök, Tufan Çınar, Nurten Sayar
INTRODUCTION: Rheumatic mitral stenosis (MS) is an important health issue in developing countries. Assessment of the correct mitral valve area (MVA) is essential for the timing of intervention. Most of the parameters for the assessment of rheumatic MS are derived from Two-dimensional (2D) echocardiography. Three-dimensional (3D) echocardiography is commonly used in our daily practice at the present time. The aim of this study was to assess the value of 3D echocardiography mitral valve vena contracta area (VCA) in predicting the severity of Rheumatic MS by comparing 3D planimetry...
December 11, 2018: Echocardiography
Kim Hébert-Losier, Ngieng Siew Yin, C Martyn Beaven, Chris Chow Li Tee, Jim Richards
Kinesiology-type tape (KTT) has become popular in sports for injury prevention, rehabilitation, and performance enhancement. Many cyclists use patella KTT; however, its benefits remain unclear, especially in uninjured elite cyclists. We used an integrated approach to investigate acute physiological, kinematic, and electromyographic responses to patella KTT in twelve national-level male cyclists. Cyclists completed four, 4-minute submaximal efforts on an ergometer at 100 and 200 W with and without patella KTT...
November 19, 2018: Journal of Electromyography and Kinesiology
Nikoloz Koshkelashvili, Priya Kohli, Jason Linefsky
CLINICAL INTRODUCTION: A 57-year-old man from the USA with a history of atrial fibrillation and hypertension was evaluated for progressive dyspnoea and decreased energy. The patient denied a history of congestive heart failure, systemic symptoms or myocardial infarction. He was found to have a 3/6 holosystolic murmur radiating to the axilla. Transthoracic echocardiography (TTE) reported a reduced ejection fraction of 40%, mitral valve regurgitation and absence of interatrial shunts. The remaining cardiac valves were without abnormality...
November 22, 2018: Heart: Official Journal of the British Cardiac Society
Valentina Volpato, Roberto M Lang, Megan Yamat, Federico Veronesi, Lynn Weinert, Gloria Tamborini, Manuela Muratori, Laura Fusini, Mauro Pepi, Davide Genovese, Victor Mor-Avi, Karima Addetia
BACKGROUND: Evaluation of the tricuspid annulus is crucial for the decision making at the time of left heart surgery. Current recommendations for tricuspid valve repair are based on two-dimensional (2D) transthoracic echocardiography (TTE), despite the known underestimation compared with three-dimensional (3D) echocardiography. However, little is known about the differences in 3D tricuspid annular (TA) sizing using TTE versus transesophageal echocardiography (TEE). The aims of this study were to (1) compare 2D and 3D TA measurements performed with both TTE and TEE and (2) compare two 3D methods for TA measurements: multiplanar reconstruction (MPR) and dedicated software (DS) designed to take into account TA nonplanarity...
November 17, 2018: Journal of the American Society of Echocardiography
Stefaan Bouchez, G Burkhard Mackensen, Eckhard Mauermann, Linda McCleish, Frederick Cobey, Madhav Swaminathan, Patrick Wouters
OBJECTIVES: In this measurement validation study, the authors evaluated agreement between 2-dimensional (2D) and three-dimensional (3D) transesophageal echocardiography (TEE), measuring anterior mitral valve leaflet length by both novice and experienced echocardiographers. DESIGN: This was a retrospective, observational study. SETTING: Single university hospital. PARTICIPANTS: Analyses on datasets from 44 patients. INTERVENTIONS: None...
July 7, 2018: Journal of Cardiothoracic and Vascular Anesthesia
Lars Fokdal, Kari Tanderup, Richard Pötter, Alina Sturdza, Kathrin Kirchheiner, Cyrus Chargari, Ina Maria Jürgenliemk-Schulz, Barbara Segedin, Li-Tee Tan, Peter Hoskin, Umesh Mahantshetty, Kjersti Bruheim, Bhavana Rai, Christian Kirisits, Jacob Christian Lindegaard
BACKGROUND: and purpose: Ureteral stricture is a rare but severe side effect, after radiotherapy for locally advanced cervical cancer (LACC). This report describes the incidence and predictive factors for ureteral stricture in a large patient cohort treated with 3D image guided adaptive brachytherapy (IGABT) and radiochemotherapy within the XXXXXXX studies. MATERIAL AND METHODS: A total of 1860 patients were included. Treatment consisted of external beam radiotherapy (45-50 Gy in 25-30 fx), concomitant Cisplatin and IGABT...
November 9, 2018: International Journal of Radiation Oncology, Biology, Physics
Flavia Ballocca, Lukas M Meier, Karim Ladha, Joshua Qua Hiansen, Eric M Horlick, Massimiliano Meineri
OBJECTIVE: The use of 3-dimensional (3D) transesophageal echocardiography (TEE) in perioperative evaluation of the mitral valve (MV) is increasing progressively, including the use of 3D MV models for quantitative analysis. However, the use of 3D MV models in clinical practice still is limited by the need for specific training and the long time required for analysis. A new stereoscopic visualization tool (EchoPixel True 3D) allows virtual examination of anatomic structures in the clinical setting, but its accuracy and feasibility for intraoperative use is unknown...
August 11, 2018: Journal of Cardiothoracic and Vascular Anesthesia
Thilo Noack, Philipp Kiefer, Linda Mallon, Philipp Lurz, Carmine Bevilacqua, Joergen Banusch, Fabian Emrich, David M Holzhey, Mani Vannan, Holger Thiele, Friedrich-Wilhelm Mohr, Michael Andrew Borger, Joerg Ender, Joerg Seeburger
BACKGROUND: The aim of this study was to quantify the acute dynamic changes of mitral valve (MV) geometry throughout the cardiac cycle-during percutaneous MV repair with the MitraClip system by 3-dimensional transesophageal echocardiography (3D TEE). METHODS: The MV was imaged throughout the cardiac cycle (CC) before and after the MitraClip procedure using 3D TEE in 28 patients (mean age, 77 ± 8 years) with functional mitral regurgitation (FMR). Dynamic changes in the MV annulus geometry and anatomical MV orifice area (AMVOA) were quantified using a novel semi-automated software...
October 5, 2018: Journal of Echocardiography
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