Chunxin Liu, WeiXiong Zhou, Xiaobo Sun, Xiayin Zhang, Hui Xiao, Hui Yang, Haotian Lin, Yaxin Lu, Zifeng Liu, Wei Qiu, Allan G Kermode, Xiaoyan Yang, Yuge Wang
BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS), autoimmune inflammatory diseases of the central nervous system, affect the optic nerve and brain. A lumbar puncture to obtain biomarkers is highly invasive. Serum biomarkers and optical coherence tomography angiography (OCTA) are more accessible and less expensive than magnetic resonance imaging and provide reliable, reproducible measures of neuroaxonal damage. This study investigated the association between serum neurofilament light chain (sNfL), serum glial fibrillary acidic protein (sGFAP), and OCTA metrics...
February 27, 2024: Multiple Sclerosis and related Disorders