Elisabeth Gjefsen, Lars Christian Haugli Bråten, Guro Løvik Goll, Monica Wigemyr, Nils Bolstad, Morten Valberg, Elina Iordanova Schistad, Gunn Hege Marchand, Fredrik Granviken, Kaja Kristine Selmer, Anne Froholdt, Anne Julsrud Haugen, Magnhild Hammersland Dagestad, Nils Vetti, Gunnstein Bakland, Benedicte Alexandra Lie, Espen A Haavardsholm, Aksel Thuv Nilsen, Thor Einar Holmgard, Thomas Istvan Kadar, Tore Kvien, Jan Sture Skouen, Lars Grøvle, Jens Ivar Brox, Ansgar Espeland, Kjersti Storheim, John Anker Zwart
BACKGROUND: Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow lesions visualized as Modic changes on magnetic resonance imaging may represent a subgroup within the low back pain population. There is evidence for inflammatory mediators being involved in development of Modic changes; hence, suppression of inflammation could be a treatment strategy for these patients...
October 21, 2020: BMC Musculoskeletal Disorders