Cristina Doina Niţu, Maria Mernea, Raluca Ioana Vlasceanu, Bianca Voicu-Balasea, Madalina Andreea Badea, Florentina Monica Raduly, Valentin Rădiţoiu, Alina Rădiţoiu, Speranta Avram, Dan F Mihailescu, Ionela C Voinea, Miruna Silvia Stan
Curcumin is a polyphenol of the Curcuma longa plant, which can be used for various medicinal purposes, such as inflammation and cancer treatment. In this context, two symmetric curcumin derivatives (D1-(1E,6E)-1,7-bis(4-acetamidophenyl)hepta-1,6-diene-3,5-dione and D2-p,p-dihydroxy di-cinnamoyl methane) were obtained by the microwave-based method and evaluated for their antitumoral effect on human cervix cancer in comparison with toxicity on non-tumoral cells, taking into account that they were predicted to act as apoptosis agonists or anti-inflammatory agents...
January 31, 2024: Pharmaceutics