Gwoncheol Park, Jennifer A Munley, Lauren S Kelly, Kolenkode B Kannan, Robert T Mankowski, Ashish Sharma, Gilbert Upchurch, Gemma Casadesus, Paramita Chakrabarty, Shannon M Wallet, Robert Maile, Letitia E Bible, Bo Wang, Lyle L Moldawer, Alicia M Mohr, Philip A Efron, Ravinder Nagpal
BACKGROUND: Sepsis and trauma are known to disrupt gut bacterial microbiome communities, but the impacts and perturbations in the fungal (mycobiome) community after severe infection or injury, particularly in patients experiencing chronic critical illness (CCI), remain unstudied. METHODS: We assess persistence of the gut mycobiome perturbation (dysbiosis) in patients experiencing CCI following sepsis or trauma for up to two-to-three weeks after intensive care unit hospitalization...
January 11, 2024: Critical Care: the Official Journal of the Critical Care Forum