Eka Pratiwi, Indah Raya, Hasnah Natsir, Rizal Irfandi, Paulina Taba, Rugaiyah Arfah, Herlina Rasyid, Yusafir Hala, Syahruddin Kasim, Andi Besse Khaerunnisa, Baso Ilham, Maulida Mazaya, Yosua Tanzil, Dewi Luthfiana
OBJECTIVE: Breast cancer ranks second in terms of the highest number of cancer deaths for women worldwide and is one of the leading causes of death from cancer in women. The drug that is often used for chemotherapy is cisplatin. However, cisplatin drugs have a number of problems, including lack of selectivity, unwanted side effects, resistance, and toxicity in the body. In this work, we investigated Ni(II) cysteine-tyrosine dithiocarbamate complex against breast cancer. METHODS: Research on the new complex compound Ni(II) cysteine-tyrosine dithiocarbamate have several stages including synthesis, characterization, in-silico and in-vitro testing of MCF-7 cells for anticancer drugs...
April 1, 2024: Asian Pacific Journal of Cancer Prevention: APJCP