Yu-Wei Zhou, Yue Ren, Miao-Miao Lu, Ling-Ling Xu, Wei-Xin Cheng, Meng-Meng Zhang, Lin-Ping Ding, Dong Chen, Jian-Guo Gao, Juan Du, Ci-Liang Jin, Chun-Xiao Chen, Yun-Fei Li, Tao Cheng, Peng-Lei Jiang, Yi-Da Yang, Peng-Xu Qian, Peng-Fei Xu, Xi Jin
Crohn's disease (CD) is caused by immune, environmental, and genetic factors. It can involve the entire gastrointestinal tract, and although its prevalence is rapidly increasing its etiology remains unclear. Emerging biological and small-molecule drugs have advanced the treatment of CD; however, a considerable proportion of patients are non-responsive to all known drugs. To achieve a breakthrough in this field, innovations that could guide the further development of effective therapies are of utmost urgency...
January 7, 2024: World Journal of Gastroenterology: WJG