Rashi Kulshrestha, Neelam Singla, Obaid Afzal, Ahsas Goyal, Mahendra Saini, Abdulmalik Saleh Alfawaz Altamimi, Waleed Hassan Almalki, Imran Kazmi, Fahad Al-Abbasi, Sami I Alzarea, Gaurav Gupta
Drug repurposing is an ongoing and clever strategy that is being developed to eradicate tuberculosis amid challenges, of which one of the major challenges is the resistance developed towards antibiotics used in standard directly observed treatment, short-course regimen. Surpassing the challenges in developing anti-tuberculous drugs, some novel host-directed therapies, repurposed drugs, and drugs with novel targets are being studied, and few are being approved too. After almost 4 decades since the approval of rifampicin as a potent drug for drugsusceptible tuberculosis, the first drug to be approved for drug-resistant tuberculosis is bedaquiline...
January 16, 2024: Current Pharmaceutical Biotechnology