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Fetal Sonography

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https://read.qxmd.com/read/30895584/-doppler-sonography-during-pregnancy-degum-quality-standards-and-clinical-applications
#1
R Faber, Kai-Sven Heling, Horst Steiner, Ulrich Gembruch
Doppler sonography is widely established in prenatal medicine and obstetrics and is commonly used in screening for aneuploidy and preeclampsia during the first trimester. More importantly, during the 2nd and 3 rd trimester, it is used in the assessment of fetal health as well as the surveillance of underlying fetal conditions such as IUGR and anemia. Correct use of the method is vital for correct data interpretation and the inferred clinical decision process. Therefore, we aim to provide all users of doppler sonography with a guide for meeting the required quality standards...
March 20, 2019: Ultraschall in der Medizin
https://read.qxmd.com/read/30662698/color-doppler-sonography-of-the-aortic-isthmus-in-intrauterine-growth-restricted-fetuses-and-normal-fetuses
#2
Ladan Younesi, Mostafa Ghadamzadeh, Ghazaleh Amjad, Zeinab Safarpour Lima
Intrauterine growth restriction is associated with a significant increase in morbidity and perinatal mortality, and increases the likelihood of fetal death, asphyxia, meconium aspiration, hypoglycemia, and neonatal hypothermia. The aim of this study was to determine aortic isthmus flow difference by using color doppler sonography in Intrauterine growth restriction and normal fetuses. The data presented were obtained from 30 mothers, who referred to the radiology department of Akbarabadi Hospital of Tehran with a diagnosis of intrauterine growth restriction...
November 2, 2018: European Journal of Translational Myology
https://read.qxmd.com/read/30648096/diagnostic-accuracy-of-ultrasound-in-detecting-retained-products-of-conception-a-study-from-a-tertiary-care-hospital-in-karachi-pakistan
#3
Hina Iqbal, Muhammad Salman Khan, Aeman Muneeb, Waseem A Mirza
Introduction Retained products of conception (RPOC) are a known complication after abortion or childbirth. To improve clinical evaluation and avoid unnecessary surgery, transvaginal scan is performed in suspected cases. However, both RPOC and blood clots appear isoechoic on ultrasound, and false positives can lead to unnecessary intervention. In this study, the ultrasound findings have been correlated with the histopathology (as a gold standard) to determine the diagnostic value of sonography in the detection of RPOC in postpartum or post-abortion patients...
November 8, 2018: Curēus
https://read.qxmd.com/read/30633342/fetal-phenotype-of-rubinstein-taybi-syndrome-caused-by-crebbp-mutations
#4
Julien Van-Gils, Sophie Naudion, Jérôme Toutain, Gwenaelle Lancelot, Tania Attié-Bitach, Sophie Blesson, Bénédicte Demeer, Bérénice Doray, Marie Gonzales, Jelena Martinovic, Sandra Whalen, Laurence Taine, Benoit Arveiler, Didier Lacombe, Patricia Fergelot
Rubinstein-Taybi syndrome (RSTS; OMIM 180849) is an autosomal dominant developmental disorder characterized by facial dysmorphism, broad thumbs and halluces associated with intellectual disability. RSTS is caused by alterations in CREBBP (about 60%) and EP300 genes (8%). RSTS is often diagnosed at birth or during early childhood but generally not suspected during antenatal period. We report nine cases of well-documented fetal RSTS. Two cases were examined after death in utero at 18 and 35 weeks of gestation and seven cases after identification of ultrasound abnormalities and termination of pregnancy...
January 11, 2019: Clinical Genetics
https://read.qxmd.com/read/30617278/a-rare-deep-intronic-mutation-of-pkhd1-gene-c-8798-459-c-a-causes-autosomal-recessive-polycystic-kidney-disease-by-pseudoexon-activation
#5
Jing Chen, Na Ma, Xiaomeng Zhao, Wen Li, Qianjun Zhang, Shimin Yuan, Yue-Qiu Tan, Guangxiu Lu, Ge Lin, Juan Du
Autosomal recessive polycystic kidney disease (ARPKD), is a rare hepatorenal fibrocystic disorder primarily associated with progressive growth of multiple cysts in the kidneys causing progressive loss of renal function. The disease is linked to mutations in the PKHD1 gene. In this study, we describe the gene diagnosis and prenatal diagnosis for a consanguineous family with two fetuses diagnosed with polycystic kidney disease by fetal sonography during the pregnancy. Sequence analysis of cDNA synthesized from the PKHD1 mRNA of the second induced fetus identified a 111-nucleotide insert at the junction of exon 56 and 57 that originated from intervening sequence (IVS) 56...
March 2019: Journal of Human Genetics
https://read.qxmd.com/read/30612473/detection-of-structural-abnormalities-in-fetuses-with-normal-karyotype-at-11-13-weeks-using-the-anatomic-examination-protocol-of-the-international-society-of-ultrasound-in-obstetrics-and-gynecology-isuog
#6
Stamatios Petousis, Alexandros Sotiriadis, Chrysoula Margioula-Siarkou, Ioannis Tsakiridis, Panagiotis Christidis, Menelaos Kyriakakis, Apostolos Mamopoulos, Apostolos Athanasiadis, Themistoklis Dagklis
OBJECTIVE: To assess the performance of sonography in the detection of fetal nonchromosomal abnormalities using a standard anatomic examination protocol proposed by International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) at 11+0 -13+6 weeks. MATERIALS AND METHODS: A prospective observational study was conducted between June 2013-May 2017 in singleton pregnancies attending for a routine scan at 11+0 -13+6 weeks. All examinations were performed by maternal-fetal medicine specialists certified by the Fetal Medicine Foundation according to the anatomic examination protocol described in the ISUOG guidelines...
January 7, 2019: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/30593696/first-trimester-abdominal-circumference-versus-crown-rump-length-improves-precision-in-inter-and-intraobserver-variability
#7
Yalda Afshar, Rachel Gutkin, Deborah Krakow, Howard Cuckle, Neil S Silverman, Lawrence D Platt
OBJECTIVES: The aim of this study was to evaluate inter- and intraobserver variability of first-trimester biometric measurements and crown-rump length (CRL) and to compare the accuracy and precision of CRL with these biometric measurements used in the interpretation of first-trimester nuchal translucency (NT). METHODS: Women presenting for a first trimester ultrasound were recruited. Both a sonographer, and a maternal fetal medicine specialist individually examined each participant...
December 28, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://read.qxmd.com/read/30580230/early-fetal-ultrasound-screening-for-major-congenital-heart-defects-without-doppler
#8
Sofía García Fernández, Javier Arenas Ramirez, Maria T Otero Chouza, Beatriz Rodriguez-Vijande Alonso, Ángel P Llaneza Coto
OBJECTIVE: Congenital heart defects are the most common major structural fetal abnormalities. Color flow mapping has played a dominant role in the detection of abnormalities during the first trimester, regardless of the International Society of Ultrasound in Obstetrics and Gynecology warning on the use of Doppler during early pregnancy. The aim of our study was to investigate the use of transvaginal two-dimensional sonography without Doppler for assessing the four-chamber view and the outflow tract view of fetuses at 11-13 weeks of gestation for cardiac screening of major congenital heart defects...
December 14, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/30577831/rationale-design-of-the-promises-study-a-prospective-assessment-and-validation-study-of-salivary-progesterone-as-a-test-for-preterm-birth-in-pregnant-women-from-rural-india
#9
Pankhuri Sharma, Simi Khan, Mohan Ghule, V B Shivkumar, Ritu Dargan, Paul T Seed, Archana Sarkar, Sunil Mehra, Poonam Varma Shivkumar, Rachel M Tribe
BACKGROUND: In India, 3.6 million pregnancies are affected by preterm birth annually, with many infants dying or surviving with disability. Currently, there is no simple test available for screening all women at risk of spontaneous PTB in low income setting, although high resource settings routinely use cervical length measurement and cervico-vaginal fluid fetal fibronectin for identification and care of women at risk due to clinical history. In rural India, where the public health system has limited infrastructure, trained staff and equipment, there is a greater need to develop a low-cost screening approach for providing early referral, treatment and remedial support for pregnant women at risk of preterm birth...
December 22, 2018: Reproductive Health
https://read.qxmd.com/read/30562798/artifacts-in-3d-prenatal-sonography
#10
Danka Miric Tesanic, Eberhard Merz
PURPOSE:  Artifacts may be part of any 3D sonographic examination during pregnancy and can disturb a routine diagnostic procedure, even simulate fetal malformation. The aim of this study was to classify the artifacts in different types according to their appearance. MATERIALS AND METHODS:  A total of 2349 healthy fetuses examined during the last five years was included in this study. The observed artifacts have been grouped into 6 different types according to their appearance: 1...
December 18, 2018: Ultraschall in der Medizin
https://read.qxmd.com/read/30554921/posterior-urethral-valves-comparison-of-clinical-outcomes-between-postnatal-and-antenatal-cohorts
#11
M A Vasconcelos, A C Simões E Silva, C S Dias, I R Gomes, R A Carvalho, S V Figueiredo, T R Dumont, M C L Oliveira, S V Pinheiro, R H Mak, E A Oliveira
BACKGROUND: Posterior urethral valves (PUVs) constitute the most common infravesical urinary obstruction in boys and are often accompanied by severe consequences to the lower and upper urinary tract. Currently, about two-thirds of diagnosis of PUVs has been suspected by prenatal ultrasonography findings. The aim of this study was to compare long-term clinical outcomes in two groups of patients with PUVs, with antenatal vs. postnatal diagnosis. STUDY DESIGN: This was a retrospective cohort study of 173 patients with PUVs systematically followed up in a tertiary center...
November 24, 2018: Journal of Pediatric Urology
https://read.qxmd.com/read/30517923/the-vermian-crest-angle-a-new-method-to-assess-fetal-vermis-position-within-the-posterior-fossa-using-3-dimensional-multiplanar-sonography
#12
Marialuigia Spinelli, Lavinia Di Meglio, Beatrice Mosimann, Edoardo Di Naro, Daniel Surbek, Luigi Raio
BACKGROUND: Normal morphometry of the vermis and its relation to the posterior fossa (PF) rule out most major anomalies of the cerebellum. However, accurate categorization of the position and size of the fetal vermis remains a challenge. OBJECTIVE: Our aim was to test a new method to assess the position and size of fetal vermis on 3-dimensional ultrasound (3D-US). METHODS: We measured the vermian-crest angle (VCA) in normal fetuses using multiplanar 3D-US...
December 5, 2018: Fetal Diagnosis and Therapy
https://read.qxmd.com/read/30443114/trends-in-referral-pattern-of-antenatally-diagnosed-surgical-abnormalities-in-a-tertiary-care-center-in-north-india
#13
Prema Menon, Vineet Binu, Katragadda Lakshmi Narasimha Rao, Vanita Suri
Aim: Pregnant women with antenatally diagnosed surgical abnormalities of the fetus are often referred for pediatric surgical consultation for likely outcome and prognosis. In this study, we analyzed the gestational age at referral to see the benefits of the same in decision-making and also looked for any change in trends of referral pattern over a period with the increasing availability of ultrasonography (USG). Materials and Methods: Records of pregnant women referred for antenatal counselling over an eight year period were analyzed...
October 2018: Journal of Indian Association of Pediatric Surgeons
https://read.qxmd.com/read/30440533/fetal-skull-reconstruction-via-deep-convolutional-autoencoders
#14
Juan J Cerrolaza, Yuanwei Li, Carlo Biffi, Alberto Gomez, Jaqueline Matthew, Matthew Sinclair, Chandni Gupta, Caroline L Knight, Daniel Rueckert
Ultrasound (US) imaging is arguably the most commonly used modality for fetal screening. Recently, 3DUS has been progressively adopted in modern obstetric practice, showing promising diagnosis capabilities, and alleviating many of the inherent limitations of traditional 2DUS, such as subjectivity and operator dependence. However, the involuntary movements of the fetus, and the difficulty for the operator to inspect the entire volume in real-time can hinder the acquisition of the entire region of interest. In this paper, we present two deep convolutional architectures for the reconstruction of the fetal skull in partially occluded 3DUS volumes: a TL deep convolutional network (TL-Net), and a conditional variational autoencoder (CVAE)...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://read.qxmd.com/read/30369120/-correlation-between-fetal-borderline-ventriculomegaly-and-chromosomal-abnormalities
#15
M He, S Hu, T Hu, Z Zhang, H Luo
Objective: To assess the association between fetal borderline ventriculomegaly (VM) diagnosed by prenatal ultrasound and chromosomal abnormality. Methods: Sonographic manifestation and chromosome of 129 cases with borderline VM diagnosed by prenatal sonography were analyzed retrospectively. All subjects were divided into 3 groups, 80 cases (62.0%, 80/129) in isolated VM (IVM) group, 27 cases (20.9%, 27/129) of VM with no additional structural abnormality group (including ultrasonic soft marker, abnormal volume of amniotic fluid and fetal growth restriction) and 22 cases (17...
October 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://read.qxmd.com/read/30290631/magnetic-resonance-imaging-of-the-fetal-brain-at-3-tesla-preliminary-experience-from-a-single-series
#16
Nivaldo Adolfo da Silva, José Vassallo, Luis Otávio Sarian, Christophe Cognard, Annick Sevely
To report our preliminary experience with cerebral fetal magnetic resonance imaging (MRI) with a 3 Tesla (3T) scanner. We assessed feasibility, time of acquisition, and possibility to establish a diagnosis.Fifty-nine pregnant women had fetal MRI performed during the third trimester of pregnancy due to clinical or sonography concern of a central nervous system anomaly. No fetal or maternal sedation was used. The MRI protocol consisted of T2 turbo-spin-echo images in 3 planes of space. No T1-weighted images were performed...
October 2018: Medicine (Baltimore)
https://read.qxmd.com/read/30251391/applicability-of-standardized-early-fetal-heart-examination-in-the-obese-population
#17
Mehmet Resit Asoglu, Ruofan Yao, Lindsey Seger, Ozhan Mehmet Turan, Sifa Turan
OBJECTIVE: This study aimed to evaluate the impact of obesity on early evaluation of fetal cardiac landmarks using a standardized examination method at the time of nuchal translucency scan. METHODS: This was a cross-sectional study of an ongoing prospective cohort at high risk for congenital heart defects. We used a standardized examination protocol using 2-dimensional sonography with power Doppler in the evaluation of fetal cardiac landmarks consisting of 4-chamber view, outflow tract relationship, and transverse arches view...
September 24, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://read.qxmd.com/read/30231662/prenatal-diagnosis-of-fetal-multiple-hemivertebrae-the-importance-of-3d-ultrasound-assessment
#18
N Volpe, C Migliavacca, A Dall'Asta, C T Kaihura, T Ghi, T Frusca
We herein present a case of fetal multiple hemivertebrae detected at antenatal sonography. The use of the 3 D technology supported by a new contrast enhancement rendering algorithm (Crystal Vue) has allowed the accurate prenatal classification of the defect, confirmed at follow up, that would have been difficult to define by 2 D only.
October 29, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/30146186/strategies-for-accurate-diagnosis-of-fetal-aortic-arch-anomalies-benefits-of-three-dimensional-sonography-with-spatiotemporal-image-correlation-and-a-novel-algorithm-for-volume-analysis
#19
Yu Wang, Miao Fan, Faiza Amber Siddiqui, Meilian Wang, Wei Sun, Xue Sun, Wenjia Lei, Ying Zhang
BACKGROUND: Obtaining an accurate diagnosis of fetal aortic arch anomalies is often difficult with traditional two-dimensional (2D) sonography. Thus, the aim of this study was to assess the value of three-dimensional (3D) sonography with spatiotemporal image correlation for diagnosing fetal aortic arch anomalies using a novel algorithm for 3D volume analysis. METHODS: Two-dimensional and 3D echocardiographic image data from 300 normal fetuses and 30 fetuses with aortic arch anomalies were retrospectively reviewed...
August 23, 2018: Journal of the American Society of Echocardiography
https://read.qxmd.com/read/30141449/feasibility-and-safety-of-chorionic-villus-sampling-cvs-for-prenatal-diagnosis-of-thalassemia-in-bangladesh
#20
R K Kazal, S A Chowdhury, T T Mirza, H H Pervin, F Noor, B Chakma, F Z Aalpona
Thalassaemia is one of the commonest inherited disorders in Bangladesh. Since population is rapidly increasing in Bangladesh, therefore birth of large number of new cases is expected every year. Chorionic villus sampling (CVS) is an invasive diagnostic procedure done in early pregnancy to obtain fetal cells for the prenatal diagnosis of chromosomal and genetic disorders like thalassemia. To investigate the feasibility, safety, and outcome of transabdominal Chorionic Villus Sampling (CVS) for prenatal diagnosis of Beta Thalassemia, this retrospective analytical study was carried out on women who had undergone transabdominal CVS for prenatal diagnosis of Beta thalassemia...
July 2018: Mymensingh Medical Journal: MMJ
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