keyword
https://read.qxmd.com/read/37637048/the-effectiveness-of-hyperbaric-oxygen-therapy-for-managing-radiation-induced-proctitis-results-of-a-10-year-retrospective-cohort-study
#21
JOURNAL ARTICLE
António Moreira Monteiro, Diogo Alpuim Costa, Virgínia Mareco, Carla Espiney Amaro
INTRODUCTION: Despite modern radiotherapy (RT) techniques, radiation-induced proctitis (RIP) remains a significant complication of RT for pelvic organ malignancies. Over the last decades, an enormous therapeutic armamentarium has been considered in RIP, including hyperbaric oxygen therapy (HBOT). However, the evidence regarding the impact of HBOT on RIP is conflicting. This study aims to evaluate the effectiveness and safety of HBOT in the treatment of RIP. METHODS: Ten-year (2013-2023) retrospective analysis of all consecutive patients with RIP treated with HBOT at Centro de Medicina Subaquática e Hiperbárica (CMSH) (Armed Forces Hospital - Lisbon, Portugal)...
2023: Frontiers in Oncology
https://read.qxmd.com/read/37585677/hyperbaric-oxygen-therapy-for-late-radiation-tissue-injury
#22
REVIEW
Zhiliang Caleb Lin, Michael H Bennett, Glen C Hawkins, Charles Paul Azzopardi, John Feldmeier, Robert Smee, Christopher Milross
BACKGROUND: This is the third update of the original Cochrane Review published in July 2005 and updated previously in 2012 and 2016. Cancer is a significant global health issue. Radiotherapy is a treatment modality for many malignancies, and about 50% of people having radiotherapy will be long-term survivors. Some will experience late radiation tissue injury (LRTI), developing months or years following radiotherapy. Hyperbaric oxygen therapy (HBOT) has been suggested as a treatment for LRTI based on the ability to improve the blood supply to these tissues...
August 15, 2023: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/37534945/osteoradionecrosis-treatment-in-head-and-neck-cancer-patients-an-overview-of-systematic-reviews
#23
REVIEW
Gabriella Torres Schroter, Renata Maria Mamprin Stopiglia, Giovanna Lopes Carvalho, Susana Morimoto, Maria Emília Mota, Fábio Abreu Alves, Graziella Chagas Jaguar, Maria Stella Moreira
AIMS: Evaluate the existing evidence of osteoradionecrosis (ORN) treatment in adults with head and neck cancer, the methodological quality and the evidence grade within systematic reviews (SRs). METHODS: An extensive systematic literature search of SRs that addressed ORN in head and neck cancer patients was conducted with screening of eligible studies, data extraction, methodological (AMSTAR 2) and evidence quality assessment (GRADE) of the SRs by independent and calibrated authors...
August 3, 2023: Special Care in Dentistry
https://read.qxmd.com/read/37475066/-research-progress-in-prevention-and-treatment-of-radiation-induced-intestinal-injury-by-traditional-chinese-medicine-active-components
#24
JOURNAL ARTICLE
Chuang-Chuang Wang, Hong-Xin Ning, Hang Li, Mei-Jing Liang, Meng-Yi Li, Shuai Wang, Jiang-Hong Guo, Yi-Liang Li, Wen-Bin Hou
Radiation-induced intestinal injury(RIII), a common complication of radiotherapy for pelvic malignancies, affects the quality of life and the radiotherapy efficacy for cancer. Currently, the main clinical approaches for the prevention and treatment of RIII include drug therapy, hyperbaric oxygen therapy, and surgical treatment. Among these methods, drug therapy is cost-effective. Traditional Chinese medicine(TCM) containing a variety of active components demonstrates mild side effects and good efficacy in preventing and treating RIII...
July 2023: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://read.qxmd.com/read/37404838/hemorrhagic-cystitis-making-rapid-and-shrewd-clinical-and-surgical-decisions-for-improving-patient-outcomes
#25
REVIEW
Francis A Jefferson, Brian J Linder
Hemorrhagic cystitis (HC) can be one of the most challenging clinical scenarios for urologists to manage. It most commonly occurs as a toxicity of pelvic radiation therapy or in patients treated with the oxazaphosphorine class of chemotherapy. Successful management of HC necessitates a stepwise approach with a thorough understanding of the various treatment options. Once ensuring hemodynamic stability, conservative management includes establishing bladder drainage, manual clot evacuation, and continuous bladder irrigation through a large-bore urethral catheter...
2023: Research and Reports in Urology
https://read.qxmd.com/read/37310931/review-of-the-pathogenesis-diagnosis-and-management-of-osteoradionecrosis-of-the-femoral-head
#26
JOURNAL ARTICLE
Yang Li, Zhongsheng Zhou, Shenghao Xu, Jinlan Jiang, Jianlin Xiao
Osteoradionecrosis (ORN) of the femoral head is an important issue for orthopedists and radiologists in clinical practice. With the rapid development of technological advances in radiation therapy and the improvement in cancer survival rates, the incidence of ORN is rising, and there is an unmet need for basic and clinical research. The pathogenesis of ORN is complex, and includes vascular injury, mesenchymal stem cell injury, bone loss, reactive oxygen species, radiation-induced fibrosis, and cell senescence...
June 13, 2023: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/37174078/the-role-of-hypoxia-and-cancer-stem-cells-in-development-of-glioblastoma
#27
REVIEW
Tingyu Shi, Jun Zhu, Xiang Zhang, Xinggang Mao
Glioblastoma multiform (GBM) is recognized as the most malignant brain tumor with a high level of hypoxia, containing a small population of glioblastoma stem like cells (GSCs). These GSCs have the capacity of self-renewal, proliferation, invasion and recapitulating the parent tumor, and are major causes of radio-and chemoresistance of GBM. Upregulated expression of hypoxia inducible factors (HIFs) in hypoxia fundamentally contributes to maintenance and progression of GSCs. Therefore, we thoroughly reviewed the currently acknowledged roles of hypoxia-associated GSCs in development of GBM...
May 4, 2023: Cancers
https://read.qxmd.com/read/37126076/effects-of-an-early-intervention-with-hyperbaric-oxygen-treatment-on-arm-lymphedema-and-quality-of-life-after-breast-cancer-an-explorative-clinical-trial
#28
JOURNAL ARTICLE
Gunn Ammitzbøll, Ole Hyldegaard, Martin Forchhammer, Henrik Rottensten, Charlotte Lanng, Niels Kroman, Bo Zerahn, Lars Thorbjørn Jensen, Christoffer Johansen, Susanne Oksbjerg Dalton
PURPOSE: Lymphedema (LE) is a common complication after breast cancer treatment, which negatively affects the quality of life (QOL). Hyperbaric Oxygen Treatment (HBOT) is an established treatment for radiation-induced tissue injury, but evidence of effect on breast cancer-related LE is inconclusive. We aimed to explore effects of HBOT on early breast cancer-related LE and the implications for QOL. METHODS: We invited women with breast cancer treated with surgery, axillary dissection and radiotherapy, who had participated in a randomized controlled trial and who presented with LE 1 year after surgery...
May 1, 2023: Supportive Care in Cancer
https://read.qxmd.com/read/37115301/-interstitial-cystitis-bladder-pain-syndrome-ic-bps
#29
REVIEW
Winfried Vahlensieck
BACKGROUND: In this review, aspects of interstitial cystitis/bladder pain syndrome (IC/BPS) are presented against the background of the German S2k guideline on this disease. OBJECTIVE: Quite often this disease, characterized by bladder or lower abdominal pain (permanent or intermittent) and pollakisuria without pathogenic bacteria in the urine culture, is diagnosed much too late. MATERIALS AND METHODS: The debate on disease definition, aspects on pathophysiology and epidemiology are presented...
April 28, 2023: Urologie
https://read.qxmd.com/read/37114827/hyperbaric-oxygen-activates-enzyme-driven-cascade-reactions-for-cooperative-cancer-therapy-and-cancer-stem-cells-elimination
#30
JOURNAL ARTICLE
Yuxuan Xiong, Zhengtao Yong, Chen Xu, Qingyuan Deng, Qiang Wang, Shiyou Li, Chong Wang, Zhijie Zhang, Xiangliang Yang, Zifu Li
Tumor starvation induced by intratumor glucose depletion emerges as a promising strategy for anticancer therapy. However, its antitumor potencies are severely compromised by intrinsic tumor hypoxia, low delivery efficiencies, and undesired off-target toxicity. Herein, a multifunctional cascade bioreactor (HCG), based on the self-assembly of pH-responsive hydroxyethyl starch prodrugs, copper ions, and glucose oxidase (GOD), is engineered, empowered by hyperbaric oxygen (HBO) for efficient cooperative therapy against aggressive breast cancers...
April 28, 2023: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/37007498/a-review-on-the-research-progress-on-non-pharmacological-therapy-of-helicobacter-pylori
#31
REVIEW
Qian Luo, Na Liu, Sugui Pu, Ze Zhuang, Hang Gong, Dekui Zhang
Helicobacter pylori is a pathogenic microorganism that mainly resides in the human stomach and is the major cause of chronic gastritis, peptic ulcer and gastric cancer. Up to now, the treatment of Helicobacter pylori has been predominantly based on a combination of antibiotics and proton pump inhibitors. However, the increasing antibiotic resistance greatly limits the efficacy of anti- Helicobacter pylori treatment. Turning to non-antibiotic or non-pharmacological treatment is expected to solve this problem and may become a new strategy for treating Helicobacter pylori ...
2023: Frontiers in Microbiology
https://read.qxmd.com/read/36984755/analysis-of-volatile-organic-compounds-in-exhaled-breath-following-a-comex-30-treatment-table
#32
JOURNAL ARTICLE
Feiko J M de Jong, Thijs T Wingelaar, Paul Brinkman, Pieter-Jan A M van Ooij, Anke H Maitland-van der Zee, Markus W Hollmann, Rob A van Hulst
The COMEX-30 hyperbaric treatment table is used to manage decompression sickness in divers but may result in pulmonary oxygen toxicity (POT). Volatile organic compounds (VOCs) in exhaled breath are early markers of hyperoxic stress that may be linked to POT. The present study assessed whether VOCs following COMEX-30 treatment are early markers of hyperoxic stress and/or POT in ten healthy, nonsmoking volunteers. Because more oxygen is inhaled during COMEX-30 treatment than with other treatment tables, this study hypothesized that VOCs exhaled following COMEX-30 treatment are indicators of POT...
February 21, 2023: Metabolites
https://read.qxmd.com/read/36913565/hyperbaric-oxygen-therapy-for-threatened-nipple-sparing-mastectomy-flaps-an-adjunct-for-flap-salvage
#33
REVIEW
Hani Y Nasr, William J Rifkin, John N Muller, Ernest S Chiu
BACKGROUND: Nipple-sparing mastectomy (NSM) is emerging as the standard of care for treatment of breast cancer because of its oncologic safety and superior aesthetic outcomes. However, ischemia or necrosis of the skin flap and/or nipple-areola complex remain frequent complications. Hyperbaric oxygen therapy (HBOT) has emerged as a potential adjunct for flap salvage, although it is not currently a widely accepted practice. Here we review our institution's experience using a protocol of HBOT in patients with signs of flap ischemia or necrosis after NSM...
May 1, 2023: Annals of Plastic Surgery
https://read.qxmd.com/read/36833823/hypoxia-pathway-in-osteoporosis-laboratory-data-for-clinical-prospects
#34
REVIEW
Jianping Wang, Bin Zhao, Jingmin Che, Peng Shang
The hypoxia pathway not only regulates the organism to adapt to the special environment, such as short-term hypoxia in the plateau under normal physiological conditions, but also plays an important role in the occurrence and development of various diseases such as cancer, cardiovascular diseases, osteoporosis. Bone, as a special organ of the body, is in a relatively low oxygen environment, in which the expression of hypoxia-inducible factor (HIF)-related molecules maintains the necessary conditions for bone development...
February 10, 2023: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/36820802/successful-treatment-of-radiation-induced-vaginal-soft-tissue-radionecrosis-with-hbo2
#35
JOURNAL ARTICLE
John McGlynn, Marvin Heyboer
INTRODUCTION: Radiation therapy to the pelvis can result in radiation-induced vaginal soft tissue necrosis. This significantly impacts quality of life. Studies evaluating the efficacy of HBO2 are limited. METHODS: In this retrospective report, we reviewed the medical records of patients treated with once-daily HBO2 for radiation-induced vaginal soft tissue necrosis. We included females between the ages of 18 to 90 with history of pelvic cancer treated with radiotherapy and resultant soft tissue radionecrosis...
2023: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://read.qxmd.com/read/36733565/delayed-presentation-of-air-embolism-within-cerebral-arteries-following-computed-tomography-guided-lung-biopsy
#36
Cunli Yang, Shao J Ong, Stanley E Loh, Gopinathan Anil
Computed tomography (CT)-guided percutaneous core needle biopsy of the lung is a frequently performed interventional radiological procedure. Most complications are minor and self-resolving. However, a rare but potentially fatal complication is that of systemic air embolism, especially when to the cerebral or coronary arteries. This study reports a case of delayed (12 hours after initial biopsy) air embolism in the cerebral arteries that resulted from an otherwise uncomplicated biopsy of a lung nodule. It is vital for early diagnostic confirmation and appropriate treatment if possible, though maximal efforts at prevention are still recommended...
January 2023: Curēus
https://read.qxmd.com/read/36727291/low-cost-high-pressure-synthesized-oxygen-entrapping-materials-to-improve-treatment-of-solid-tumors
#37
JOURNAL ARTICLE
Jianling Bi, Emily Witt, Vanessa A Voltarelli, Vivian R Feig, Veena Venkatachalam, Hannah Boyce, Megan McGovern, Wade R Gutierrez, Jeffrey D Rytlewski, Kate R Bowman, Ashley C Rhodes, Austin N Cook, Benjamin N Muller, Matthew G Smith, Alexis Rebecca Ramos, Heena Panchal, Rebecca D Dodd, Michael D Henry, Adam Mailloux, Giovanni Traverso, Leo E Otterbein, James D Byrne
Tumor hypoxia drives resistance to many cancer therapies, including radiotherapy and chemotherapy. Methods that increase tumor oxygen pressures, such as hyperbaric oxygen therapy and microbubble infusion, are utilized to improve the responses to current standard-of-care therapies. However, key obstacles remain, in particular delivery of oxygen at the appropriate dose and with optimal pharmacokinetics. Toward overcoming these hurdles, gas-entrapping materials (GeMs) that are capable of tunable oxygen release are formulated...
February 2, 2023: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/36642024/adjunctive-hyperbaric-oxygen-therapy-with-reconstruction-of-lower-eyelid-for-basal-cell-carcinoma-a-case-series
#38
JOURNAL ARTICLE
Mendy Hatibie Oley, Maximillian Christian Oley, Deborah Florencia Gunawan, Andi A Rangan, Angelica Maurene Joicetine Wagiu, Muhammad Faruk
INTRODUCTION: Basal cell carcinoma (BCC) is among the most widespread non-melanoma skin cancers, with an incidence of around 80 % worldwide. Surgery is the main therapy of choice. High-pressure oxygen is used in hyperbaric oxygen therapy (HBO) to treat hypoxic tissue conditions. By using this technique, the tissue oxygen tensions increase. This is used to treat a wide range of diseases and disorders brought on by hypoxic states, circulation issues, inadequate tissue oxygenation due to vascular damage, tissue damage from infections or accidents, and impairment of tissue healing...
January 11, 2023: International Journal of Surgery Case Reports
https://read.qxmd.com/read/36587606/hyperbaric-oxygen-therapy-for-local-late-radiation-toxicity-in-breast-cancer-patients-a-systematic-review
#39
REVIEW
E L Meier, D R Mink van der Molen, C A Lansdorp, M C T Batenburg, F van der Leij, H M Verkooijen, O Boonstra, S Hummelink, D J O Ulrich
PURPOSE: This systematic review aims to provide an overview of the literature on the effect of hyperbaric oxygen therapy (HBOT) on symptoms of local late radiation toxicity (LRT) in patients treated for breast cancer. METHODS: A systematic search was performed in September 2021. All studies with a sample size of ≥10 patients reporting the effect of HBOT for symptoms of LRT after radiotherapy of the breast and/or chest wall were included. The ROBINS-I tool was used for critical appraisal of methodological quality...
February 2023: Breast: Official Journal of the European Society of Mastology
https://read.qxmd.com/read/36525211/the-potential-of-hyperbaric-oxygen-as-a-therapy-for-neurodegenerative-diseases
#40
REVIEW
Paapa Mensah-Kane, Nathalie Sumien
The World Health Organization estimates that by the year 2040, neurodegenerative diseases will be the second leading cause of death in developed countries, overtaking cancer-related deaths and exceeded only by cardiovascular disease-related death. The search for interventions has therefore become paramount to alleviate some of this burden. Based on pathways affected in neurodegenerative diseases, hyperbaric oxygen treatment (HBOT) could be a good candidate. This therapy has been used for the past 50 years for conditions such as decompression sickness and wound healing and has been shown to have promising effects in conditions associated with neurodegeneration and functional impairments...
April 2023: GeroScience
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