Shan Cao, Shuangrong Gao, Chen Ni, Yingli Xu, Bo Pang, Jingsheng Zhang, Yu Zhang, Yaxin Wang, Zihan Geng, Shurang Li, Ronghua Zhao, Bing Han, Xiaolan Cui, Yanyan Bao
ETHNOPHARMACOLOGICAL RELEVANCE: Urinary tract infections (UTIs) are globally prevalent infectious diseases, predominantly caused by uropathogenic Escherichia coli (UPEC). The misuse of antibiotics has led to the emergence of several drug-resistant strains. Traditional Chinese Medicine (TCM) has its own advantages in the treatment of UTIs. HJ granules is a herbal formula used for the treatment of UTIs. However, its mechanism of action is not clear. AIM OF THE STUDY: The aim of this study was to investigate the therapeutic efficacy and mechanism of action of HJ granules in a rat model of UTI caused by Escherichia coli (E coli) CFT073...
March 13, 2024: Journal of Ethnopharmacology