keyword
https://read.qxmd.com/read/38533133/non-tamponade-indications-for-pericardial-drainage-a-case-report-of-acute-streptococcus-pneumoniae-purulent-pericarditis
#1
Toyin Ingram, Aarti Narayan, Noah Ene, Iheoma Kwazemem-Opara, Chika Okafor
Pericardial drainage is a procedure completed to evacuate fluid from the pericardial space. This can be completed by pericardiocentesis or pericardial window. These procedures are most often done in the setting of cardiac tamponade, typically to correct low blood pressure due to low stroke volume from extrinsic compression of the heart chambers by the pericardial fluid. Elective pericardiocentesis can be done in cases where fluid accumulation is secondary to pathological processes, including hemopericardium secondary to complications of trauma to the chest, toxins, myocardial infarction, cardiac surgery, serosanguinous pericardial effusion due to malignancy, right heart failure, acute pericarditis, chemotherapeutic agents, metabolic derangements like uremia, and autoimmune disorders...
February 2024: Curēus
https://read.qxmd.com/read/38533114/whole-genome-sequencing-data-of-streptococcus-pneumoniae-isolated-from-indonesian-population
#2
JOURNAL ARTICLE
Miftahuddin Majid Khoeri, Yustinus Maladan, Korrie Salsabila, Lindawati Alimsardjono, Naritha Vermasari, Iva Puspitasari, Rina Yunita, Wisnu Tafroji, Rosantia Sarassari, Ratna Fathma Sari, Sarah Azhari Balqis, Ghina Athyah Wahid, Diana Shinta Purwanto, Kuntjoro Harimurti, Amin Soebandrio, Dodi Safari
Streptococcus pneumoniae is the leading cause of bacterial pneumonia, bacteremia, and meningitis. Indonesia introduced the pneumococcal conjugate vaccine (PCV) nationwide in 2022. In this study, we present whole genome sequence (WGS) data of 94 S. pneumoniae isolates that were obtained from hospitalized patients, healthy children, and adult groups from different regions prior to PCV program in Indonesia. DNA sequences of S. pneumoniae were obtained using the TruSeq Nano DNA kit (Illumina NovaSeq6000 Platform)...
April 2024: Data in Brief
https://read.qxmd.com/read/38532828/clinical-characteristics-and-microorganisms-isolated-in-community-acquired-pneumonia-in-the-covid-19-period
#3
JOURNAL ARTICLE
Meritxell Gavalda, Maria Isabel Fullana, Adrià Ferre, Rebecca Rowena Peña, Julen Armendariz, Orla Torrallardona, Aina Magraner, Alejandro Lorenzo, Carles García, Gemma Mut, Lluís Planas, Carla Iglesias, Pablo Fraile-Ribot, Maria Dolores Macia Romero, Melchor Riera, Mercedes García-Gasalla
INTRODUCTION: Community-acquired pneumonia is a leading cause of mortality and hospital admissions. The aetiology remains unknown in 30-65% of the cases. Molecular tests are available for multiple pathogen detection and are under research to improve the causal diagnosis. METHODS: We carried out a prospective study to describe the clinical characteristics and aetiology of community-acquired pneumonia during the COVID-19 pandemic and to assess the diagnostic effectivity of the microbiological tests, including a molecular test of respiratory pathogens (FilmArray™ bioMérieux)...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38531552/infectious-purpura-fulminans-associated-with-pneumococcal-septicaemia-in-a-patient-with-unacknowledged-functional-asplenia
#4
JOURNAL ARTICLE
Savannah Duus, Sanne Jespersen, Christian Wejse
Purpura fulminans (PF) is a life-threatening complication of septic shock that can occur due to disseminated infections with Streptococcus pneumoniae The spleen is an important organ in the immunisation process against encapsulated bacteria. Patients with asplenia, either functional or anatomical, are therefore at increased risk of developing serious infections and complications, such as PF, if infected with such bacteria.This case report presents a woman in her late 40s with unacknowledged functional asplenia who was admitted to the hospital with signs of an acute disseminated infection causing septic shock, signs of disseminated intravascular coagulation and infectious PF...
March 25, 2024: BMJ Case Reports
https://read.qxmd.com/read/38530917/clonal-expansion-of-a-streptococcus-pneumoniae-serotype-3-capsule-variant-sequence-type-700-with-enhanced-vaccine-escape-potential-after-13-valent-pneumococcal-conjugate-vaccine-introduction
#5
JOURNAL ARTICLE
Akuzike Kalizang'oma, Todd D Swarthout, Thandie S Mwalukomo, Arox Kamng'ona, Comfort Brown, Jacquline Msefula, Hayley Demetriou, Jia Mun Chan, Lucy Roalfe, Uri Obolski, Jose Lourenço, David Goldblatt, Chrispin Chaguza, Neil French, Robert S Heyderman
BACKGROUND: Streptococcus pneumoniae serotype 3 remains a problem globally. Malawi introduced 13-valent pneumococcal conjugate vaccine (PCV13) in 2011, but there has been no direct protection against serotype 3 carriage. We explored whether vaccine escape by serotype 3 is due to clonal expansion of a lineage with a competitive advantage. METHODS: The distribution of serotype 3 Global Pneumococcal Sequence Clusters (GPSCs) and sequence types (STs) globally was assessed using sequences from the Global Pneumococcal Sequencing Project...
March 26, 2024: Journal of Infectious Diseases
https://read.qxmd.com/read/38529473/spectrum-and-antibiotic-sensitivity-of-bacterial-keratitis-a-retrospective-analysis-of-eight-years-in-a-tertiary-referral-hospital-in-southwest-china
#6
JOURNAL ARTICLE
Rui-Qin Guo, Ji Yang, Ya-Bin Yang, Ya-Nan Chen, Yu-Yuan Xiao, Ping Xiang, Meng-Jie Dong, Min-Fang He, Yin-Ting Wang, Yun-Ling Xiao, Hong-Qin Ke, Hai Liu
PURPOSE: The objective of this study was to investigate the epidemiological characteristics, distribution of isolates, prevailing patterns, and antibiotic susceptibility of bacterial keratitis (BK) in a Tertiary Referral Hospital located in Southwest China. METHODS: A retrospective analysis was conducted on 660 cases of bacterial keratitis occurring between January 2015 and December 2022. The demographic data, predisposing factors, microbial findings, and antibiotic sensitivity profiles were examined...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38527500/-a-multicenter-study-on-respiratory-pathogen-detection-with-mycoplasma-pneumoniae-pneumonia-in-children
#7
JOURNAL ARTICLE
X Y Dong, Y X Zou, F F Lyu, W H Yang, H L Zhang, Y H Niu, H J Wang, R Guo, X Wang, L Li, Z H Lin, L Luo, D L Lu, Q Lu, H M Liu, L N Chen
Objective: To analyze the status of respiratory pathogen detection and the clinical features in children with Mycoplasma pneumoniae pneumonia (MPP). Methods: A prospective, multicenter study was conducted to collect clinical data, including medical history, laboratory examinations and multiplex PCR tests of children diagnosed with MPP from 4 hospitals in China between November 15th and December 20th , 2023. The multiplex PCR results and clinical characteristics of MPP children in different regions were analyzed...
March 25, 2024: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/38524231/things-we-do-for-no-reason-ordering-streptococcus-pneumoniae-urinary-antigen-in-patients-with-community-acquired-pneumonia
#8
JOURNAL ARTICLE
Matthew R Davis, Erin K McCreary, Alex M Trzebucki
No abstract text is available yet for this article.
March 2024: Open Forum Infectious Diseases
https://read.qxmd.com/read/38523046/development-of-an-antimicrobial-3d-printable-denture-base-material-with-k18-quaternary-ammonium-silane-functionalized-methyl-methacrylate-and-filler
#9
JOURNAL ARTICLE
Mansi Patel, Leslie Barrera, Lianrui Chu, Kyumin Whang
STATEMENT OF PROBLEM: Denture base materials are highly susceptible to microbial colonization, which can lead to denture stomatitis. In addition, patients who sleep with their dentures have an increased chance of contracting pneumonia. Commercially available antimicrobial denture base materials to prevent or combat microbial colonization are lacking. PURPOSE: The purpose of this in vitro study was to determine the effects of K18 quaternary ammonium methacryloxy silane-functionalized filler (K18-Filler) and methyl methacrylate (K18-MMA) on the polymerization of 3D printed denture base material and its esthetic, mechanical, and antimicrobial properties...
March 23, 2024: Journal of Prosthetic Dentistry
https://read.qxmd.com/read/38522137/magnolol-attenuates-macrophage-pyroptosis-triggered-by-streptococcus-equi-subsp-zooepidemicus
#10
JOURNAL ARTICLE
Yuxuan Liu, Meijun Lu, Qian Sun, Zheng Guo, Yongjin Lin, Shun Li, Yunfei Huang, Yajuan Li, Qiang Fu
Streptococcus equi subsp. zooepidemicus (SEZ) is a zoonotic bacterial pathogen that causes life-threatening infections and various diseases such as meningitis, endocarditis and pneumonia. With the use of antibiotics being severely restricted in the international community, an alternative to antibiotics is urgently needed against bacterial. In the present study, the herbal extract magnolol protected mice against SEZ infection, reflected by increased survival rate and reduced bacterial burden. A pro-inflammatory form of cell death occurred in SEZ-infected macrophage...
March 23, 2024: International Immunopharmacology
https://read.qxmd.com/read/38520034/etiology-clinical-presentation-and-outcomes-of-bacterial-meningitis-in-adult-patients-a-retrospective-study-in-lithuania-2018-2021
#11
JOURNAL ARTICLE
Greta Rynkevič, Emilijus Žilinskas, Dovilė Streckytė, Daiva Radzišauskienė, Rūta Mameniškienė
BACKGROUND Bacterial meningitis is a serious and life-threatening condition that requires prompt diagnosis and treatment. This retrospective study aimed to identify causes, presentation, and predictive factors for outcomes of community-acquired bacterial meningitis in 86 adults in Vilnius, Lithuania between 2018 and 2021. MATERIAL AND METHODS We performed a retrospective study of demographic, clinical, and laboratory records of 86 adult patients admitted to Vilnius University Hospital Santaros Clinics with a diagnosis of acute bacterial meningitis during the period of 2018-2021...
March 23, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38519344/a-randomized-blind-parallel-controlled-phase-i-clinical-trial-to-evaluate-the-safety-and-preliminary-immunogenicity-of-23-valent-pneumococcal-polysaccharide-vaccine-in-healthy-people-aged-2%C3%A2-years-and-older
#12
JOURNAL ARTICLE
Yuhui Zhang, Yanxia Wang, Guangfu Li, Xue Zhao, Kai Wang, Chunyu Jia, Yongli Yang, Lili Huang, Jiebing Tan, Xiaofen Chen, Wenna Leng, Zhiqiang Xie, Wei Zhang, Juan Zong, Kang Chen, Qin Li, Xiaocan Jia, Dongyang Zhao, Youcai An, Yaodong Zhang
BACKGROUND: Despite some progress in pneumococcal immunization, the global burden of pneumococcal infection remains high, and pneumococcal disease remains a public health concern. Studies in China and abroad have found that 23-valent pneumococcal polysaccharide vaccine (PPV23) vaccination can effectively prevent invasive pneumococcal disease. This phase Ⅰ clinical study assessed the safety and immunogenicity of a PPV23 vaccine candidate. METHODS: All subjects were randomly assigned to receive one dose intramuscular injection of experimental vaccine or control vaccine at a ratio of 1:1...
March 21, 2024: Vaccine
https://read.qxmd.com/read/38518150/application-of-thermal-cycling-amplification-chip-method-in-the-detection-of-respiratory-machine-associated-pneumonia-pathogens
#13
JOURNAL ARTICLE
Jiajia Liu, Shuai Zhao, Haiyang Yan, Suli Jin, Jingna Sun, Lidan Xing, Xiaoye Liu, Lisha Wang, Jing Chen
OBJECTIVE: Investigating the application effectiveness of using loop-mediated isothermal amplification (LAMP) on a microfluidic chip to detect the pathogens associated with ventilator-associated pneumonia (VAP). METHODS: Eighty samples of bronchoalveolar lavage fluid from patients with ventilator-associated pneumonia (VAP) were collected at The First Hospital of Hebei Medical University from July 2022 to July 2023. The bacterial culture technique and the LAMP method were used to detect the nucleic acid of the pathogens in the patient samples...
March 22, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38517865/aetiological-agents-of-pneumonia-among-hiv-and-non-hiv-infected-children-in-ghana-a-case-control-study
#14
JOURNAL ARTICLE
Michael Owusu, Eric Adu, Lotenna Elsie Kalu, Eugene Martey, Godfred Acheampong, Anthony Enimil, John Adabie Appiah, Augustina Badu-Peprah, Justice Sylverken, Augustina Angelina Sylverken, Samuel Blay Nguah, Emilie Westeel, Stephane Pouzol, Christian Drosten, Yaw Adu-Sarkodie
Pneumonia is the leading cause of death in children, however, the microbial aetiology of pneumonia is not well elucidated in low- and middle-income countries. Our study was aimed at determining the microbial aetiologies of childhood pneumonia and associated risk factors in HIV and non-HIV infected children. We conducted a case-control study that enrolled children with pneumonia as cases and non-pneumonia as controls from July 2017 to May 2020. Induced sputum and blood samples were investigated for microbial organisms using standard microbiological techniques...
2024: PloS One
https://read.qxmd.com/read/38517265/strategies-for-pneumococcal-vaccination-in-older-adults-in-the-coming-era
#15
JOURNAL ARTICLE
Kei Nakashima, Wakaba Fukushima
Pneumonia, predominantly caused by Streptococcus pneumoniae , remains a leading cause of global mortality. The 23-valent Pneumococcal polysaccharide vaccine (PPSV23) and conjugate vaccines (PCVs) are vital measures to fight against it. This paper discussed the changes in pneumococcal vaccination strategies, particularly for older adults, as vaccine effectiveness and epidemiological patterns shift. While PPSV23 maintains effectiveness against invasive pneumococcal disease (IPD), its effectiveness against pneumococcal pneumonia is declining...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38515663/bacterial-etiology-of-community-acquired-pneumonia-among-adult-patients-in-ethiopia-a-systematic-review-and-meta-analysis
#16
JOURNAL ARTICLE
Abdurezak Mohammed Seid, Wondwossen Tadesse, Mesfin Menza, Ritbano Ahmed Abdo, Abdulhakim Mussema
BACKGROUND AND OBJECTIVE: According to the Global Burden of Diseases, Injuries, and Risk Factors, lower respiratory infections cause more than 2.3 million deaths globally, with a majority occurring in sub-Saharan Africa, including Ethiopia.Community-acquired pneumonia (CAP) is a major contributor to global mortality and morbidity. Understanding the prevalence and common bacterial causes of CAP is crucial for clinicians to accurately diagnose and improve patient satisfaction. The purpose of this systematic review was to report the pooled prevalence and common bacterial etiologies of CAP among adult patients in Ethiopia...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38515059/the-assessment-of-microbial-infection-in-children-with-autism-spectrum-disorders-and-genetic-folate-cycle-deficiency
#17
JOURNAL ARTICLE
Dmitry Maltsev, Iryna Solonko, Olena Sydorenko
BACKGROUND: The results of disparate clinical studies indicate abnormally frequent cases of certain microorganisms in children with autism spectrum disorders (ASD). However, these data require clarification and systematization. The study aims to study the structure of the microbial profile in children with ASD and genetic folate cycle deficiency (GFCD) and consider differences in diagnostic approaches for identifying microorganisms of different types. METHODS: The study analyzed medical data from 240 children (187 boys and 63 girls) with GFCD aged 2 to 9 years...
March 21, 2024: BMC Pediatrics
https://read.qxmd.com/read/38514352/streptococcus-pneumoniae-as-a-colonizing-agent-of-the-nasopharynx-oropharynx-in-adults-a-systematic-review-and-meta-analysis
#18
REVIEW
Julián Lozada, Juan Olivella Gómez, Cristian C Serrano-Mayorga, André Emilio Viñán Garcés, Valeria Enciso, Lina Mendez-Castillo, Alejandro Acosta-González, Ingrid G Bustos, Yuli V Fuentes, Elsa D Ibáñez-Prada, Ana M Crispin, María C Delgado-Cañaveral, Lina María Morales Celis, Diego Jaimes, Paul Turner, Luis Felipe Reyes
BACKGROUND: Streptococcus pneumoniae (Spn) is a commensal pathogen that usually colonizes the upper respiratory tract of children. Likewise, Spn colonization has been considered a critical factor in the development of pneumococcal invasive disease. However, Spn prevalence in adults remains unclear. This study performs a systematic review and meta-analysis to explore the prevalence of Spn Nasopharynx - Oropharynx Colonization (NOC) in adults. METHODS: A Systematic review of scientific databases was utilized to identify eligible studies that follow strict selection criteria...
March 20, 2024: Vaccine
https://read.qxmd.com/read/38507601/estimating-between-country-migration-in-pneumococcal-populations
#19
JOURNAL ARTICLE
Sophie Belman, Henri Pesonen, Nicholas J Croucher, Stephen D Bentley, Jukka Corander
Streptococcus pneumoniae (the pneumococcus) is a globally distributed, human obligate opportunistic bacterial pathogen which, although often carried commensally, is also a significant cause of invasive disease. Apart from multi-drug resistant and virulent clones, the rate and direction of pneumococcal dissemination between different countries remains largely unknown. The ability for the pneumococcus to take a foothold in a country depends on existing population configuration, the extent of vaccine implementation, as well as human mobility since it is a human obligate bacterium...
March 20, 2024: G3: Genes—Genomes—Genetics
https://read.qxmd.com/read/38506028/-acute-and-chronic-rhinosinusitis-age-characteristics
#20
JOURNAL ARTICLE
S V Ryazantsev, I M Kirichenko, E L Savlevich, V I Popadyuk, N S Kozlova, A I Chernolev
Children's and adults' rhinosinusitis are two diseases that have both similarities and differences in anatomy, epidemiology, causes, pathogenesis, diagnosis and treatment. At the same rhinosinusitis is one of the most common in otorhinolaryngology's practice, both in children and adults. The of adults paranasal sinuses (PNS) anatomy differs from children's PNS anatomy. Although ostiomeatal complex occlusion is recognized as a major cause of poor ventilation and drainage of the adult paranasal sinuses, it does not have a strong effect on pediatric rhinosinusitis, but adenoids play a key role...
2024: Vestnik Otorinolaringologii
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