keyword
https://read.qxmd.com/read/38309959/-standard-technical-specifications-for-methacholine-chloride-methacholine-bronchial-challenge-test-2023
#21
JOURNAL ARTICLE
(no author information available yet)
The methacholine challenge test (MCT) is a standard evaluation method of assessing airway hyperresponsiveness (AHR) and its severity, and has significant clinical value in the diagnosis and treatment of bronchial asthma. A consensus working group consisting of experts from the Pulmonary Function and Clinical Respiratory Physiology Committee of the Chinese Association of Chest Physicians, the Task Force for Pulmonary Function of the Chinese Thoracic Society, and the Pulmonary Function Group of Respiratory Branch of the Chinese Geriatric Society jointly developed this consensus...
February 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38297277/predicting-the-10-year-incidence-of-dyslipidemia-based-on-novel-anthropometric-indices-using-data-mining
#22
JOURNAL ARTICLE
Alireza Takhttavous, Maryam Saberi-Karimian, Somayeh Ghiasi Hafezi, Habibollah Esmaily, Marzieh Hosseini, Gordon A Ferns, Elham Amirfakhrian, Mark Ghamsary, Majid Ghayour-Mobarhan, Maryam Alinezhad-Namaghi
BACKGROUND: The aim was to establish a 10-year dyslipidemia incidence model, investigating novel anthropometric indices using exploratory regression and data mining. METHODS: This data mining study was conducted on people who were diagnosed with dyslipidemia in phase 2 (n = 1097) of the Mashhad Stroke and Heart Atherosclerotic Disorder (MASHAD) study, who were compared with healthy people in this phase (n = 679). The association of dyslipidemia with several novel anthropometric indices including Conicity Index (C-Index), Body Roundness Index (BRI), Visceral Adiposity Index (VAI), Lipid Accumulation Product (LAP), Abdominal Volume Index (AVI), Weight-Adjusted-Waist Index (WWI), A Body Shape Index (ABSI), Body Mass Index (BMI), Body Adiposity Index (BAI) and Body Surface Area (BSA) was evaluated...
January 31, 2024: Lipids in Health and Disease
https://read.qxmd.com/read/38296348/evaluation-of-ventricular-vascular-coupling-with-critical-care-metrics-an-in-silico-approach
#23
JOURNAL ARTICLE
Lawrence J Mulligan, Justin Ungerleider, Adam Friedman, Benjamin Sanders, Julian Thrash, Daniel Ewert, Ludmil Mitrev, Jeffrey C Hill
Mean arterial pressure and cardiac output provide insufficient guidance for the management of intraoperative hypotension (IOH). In silico models offer additional insights into acute changes in hemodynamic parameters that may be encountered during IOH. A computational model (CM) generated parameters quantifying ventricular-vascular coupling, and pressure-volume construct across levels of aortic compliance (CA ). We studied how a loss from normal-to-stiff CA impacts critical care metrics of hemodynamics during vascular occlusion...
February 2024: Physiological Reports
https://read.qxmd.com/read/38285327/improving-acute-stroke-assessment-in-non-enhanced-computed-tomography-automated-tool-for-early-ischemic-lesion-volume-detection
#24
JOURNAL ARTICLE
Mara Sabina Bernardi, Alex Rodriguez, Paola Caruso, Giovanni Furlanis, Mariana Ridolfi, Gabriele Prandin, Marcello Naccarato, Alessandro Laio, Daniele Amati, Paolo Manganotti
BACKGROUND AND OBJECTIVES: ASPECTs is a widely used marker to identify early stroke signs on non-enhanced computed tomography (NECT), yet it presents interindividual variability and it may be hard to use for non-experts. We introduce an algorithm capable of automatically estimating the NECT volumetric extension of early acute ischemic changes in the 3D space. We compared the power of this marker with ASPECTs evaluated by experienced practitioner in predicting the clinical outcome. METHODS: We analyzed and processed neuroimaging data of 153 patients admitted with acute ischemic stroke...
January 29, 2024: Neurological Sciences
https://read.qxmd.com/read/38281805/-relationship-between-blood-glucose-variation-collateral-circulation-and-batman-score-and-prognosis-after-mechanical-thrombectomy-with-solitaire-stent-in-acute-posterior-vascular-occlusive-stroke
#25
JOURNAL ARTICLE
N Wang, C M Wen, J Gao, F H Bai, Y F Liu, J Sun
Objective: To explore the relationship between blood glucose variability, collateral circulation and basilar artery computed scan angiography score (Batman) and prognosis of mechanical thrombectomy with Solitaire stent in patients with large vascular occlusive APCI. Methods: A retrospective study was conducted on 113 patients with large vessel occlusive APCI who underwent Solitaire stent mechanical thrombectomy in the Department of Neurology of Nanyang Central Hospital from March 2021 to July 2022. According to the prognosis, they were divided into outcome group (46 cases) and adverse group (67 cases)...
January 30, 2024: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/38281309/effect-of-macitentan-in-pulmonary-arterial-hypertension-and-the-relationship-between-echocardiography-and-cmri-variables-repair-echocardiography-sub-study-results
#26
JOURNAL ARTICLE
Adam Torbicki, Richard Channick, Nazzareno Galiè, David G Kiely, Pamela Moceri, Andrew Peacock, Andrew J Swift, Ahmed Tawakol, Anton Vonk Noordegraaf, Dayana Flores, Nicolas Martin, Stephan Rosenkranz
INTRODUCTION: The aim of this sub-study was to evaluate the relationship between echocardiography (echo) and cardiac magnetic resonance imaging (cMRI) variables and to utilize echo to assess the effect of macitentan on right ventricle (RV) structure and function. METHODS: REPAIR (NCT02310672) was a prospective, multicenter, single-arm, open-label, 52-week, phase 4 study in pulmonary arterial hypertension (PAH) patients, which investigated the effect of macitentan 10 mg as monotherapy, or in combination with a phosphodiesterase 5 inhibitor, on RV structure, function, and hemodynamics using cMRI and right heart catheterization...
January 28, 2024: Cardiology and Therapy
https://read.qxmd.com/read/38272604/low-versus-high-stroke-volume-variation-guided-and-reduction-of-postoperative-complications-after-liver-resection-a-randomized-clinical-trial
#27
RANDOMIZED CONTROLLED TRIAL
Kai-Wei Hsieh, Wei-Yu Chen, Yuan-Yi Chia
BACKGROUND: Liver surgery is a major abdominal operation associated with a dramatic change in intraoperative hemodynamics; thus, the infusion strategy is challenging for anesthesiologists. Studies have demonstrated that stroke volume variation (SVV) can be used to predict fluid responsiveness during major abdominal surgery. SVV can be used as a guide for the administration of intraoperative fluids to improve postoperative prognosis. In the present study, we planned to investigate whether high- or low-SVV in liver surgery is associated with fewer postoperative complications...
March 1, 2023: Asian Journal of Anesthesiology
https://read.qxmd.com/read/38269628/contractility-ventriculoarterial-coupling-and-stroke-work-after-acute-myocardial-infarction-using-cmr-derived-pressure-volume-loop-data
#28
JOURNAL ARTICLE
David Nordlund, Theodor Lav, Robert Jablonowski, Ardavan Khoshnood, Ulf Ekelund, Dan Atar, David Erlinge, Henrik Engblom, Håkan Arheden
BACKGROUND: Noninvasive left ventricular (LV) pressure-volume (PV) loops derived by cardiac magnetic resonance (CMR) have recently been shown to enable characterization of cardiac hemodynamics. Thus, such PV loops could potentially provide additional diagnostic information such as contractility, arterial elastance (Ea ) and stroke work (SW) currently not available in clinical routine. This study sought to investigate to what extent PV-loop variables derived with a novel noninvasive method can provide incremental physiological information over cardiac dimensions and blood pressure in patients with acute myocardial infarction (MI)...
January 2024: Clinical Cardiology
https://read.qxmd.com/read/38261025/patterns-of-left-ventricular-remodeling-post-myocardial-infarction-determinants-and-outcome
#29
JOURNAL ARTICLE
Damien Logeart, Yoann Taille, Geneviève Derumeaux, Barnabas Gellen, Marc Sirol, Michel Galinier, François Roubille, Jean-Louis Georges, Jean-Noël Trochu, Jean-Marie Launay, Nicolas Vodovar, Christophe Bauters, Eric Vicaut, Jean-Jacques Mercadier
AIM: Left ventricular remodeling (LVR) after myocardial infarction (MI) can lead to heart failure, arrhythmia, and death. We aim to describe adverse LVR patterns at 6 months post-MI and their relationships with subsequent outcomes and to determine baseline. METHODS AND RESULTS: A multicenter cohort of 410 patients (median age 57 years, 87% male) with reperfused MI and at least 3 akinetic LV segments on admission was analyzed. All patients had transthoracic echocardiography performed 4 days and 6 months post-MI, and 214 also had cardiac magnetic resonance imaging performed on day 4...
January 23, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38256528/the-heart-s-function-as-a-pump-assessed-via-impedance-cardiography-and-the-autonomic-system-balance-in-patients-with-early-stage-acromegaly
#30
JOURNAL ARTICLE
Agnieszka Jurek, Paweł Krzesiński, Robert Wierzbowski, Beata Uziębło-Życzkowska, Przemysław Witek, Grzegorz Zieliński, Anna Kazimierczak, Małgorzata Banak, Grzegorz Gielerak
BACKGROUND: Acromegaly is a rare, chronic disease that involves structural and functional abnormalities of the cardiovascular system. Acromegaly likely affects interactions between the cardiovascular system and the autonomic nervous system (ANS). Therefore, assessing the relationship between sympathetic-parasympathetic balance by analyzing heart rate variability (HRV) and the hemodynamic profile via impedance cardiography (ICG) may be useful in learning the exact nature of interactions between the ANS and the cardiovascular system...
January 11, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38248292/adaptation-of-the-concept-of-brain-reserve-for-the-prediction-of-stroke-outcome-proxies-neural-mechanisms-and-significance-for-research
#31
JOURNAL ARTICLE
Roza M Umarova, Laura Gallucci, Arsany Hakim, Roland Wiest, Urs Fischer, Marcel Arnold
The prediction of stroke outcome is challenging due to the high inter-individual variability in stroke patients. We recently suggested the adaptation of the concept of brain reserve (BR) to improve the prediction of stroke outcome. This concept was initially developed alongside the one for the cognitive reserve for neurodegeneration and forms a valuable theoretical framework to capture high inter-individual variability in stroke patients. In the present work, we suggest and discuss (i) BR-proxies-quantitative brain characteristics at the time stroke occurs (e...
January 12, 2024: Brain Sciences
https://read.qxmd.com/read/38246939/dysautonomia-and-activity-in-the-early-stroke-recovery-period
#32
REVIEW
Amelia Tenberg, Nozomi Tahara, Amit Grewal, Alison Herrera, Lisa M Klein, Rachael Lebo, Elizabeth K Zink, Mona N Bahouth
Maintaining cerebral perfusion in the early stages of recovery after stroke is paramount. Autoregulatory function may be impaired during this period leaving cerebral perfusion directly reliant on intravascular volume and blood pressure (BP) with increased risk for expanding cerebral infarction during periods of low BP and hemorrhagic transformation during BP elevations. We suspected that dysautonomia is common during the acute period related to both pre-existing vascular risk factors and potentially independent of such conditions...
January 21, 2024: Neurological Sciences
https://read.qxmd.com/read/38237576/individualizing-basketball-specific-interval-training-using-anaerobic-speed-reserve-effects-on-physiological-and-hormonal-adaptations
#33
JOURNAL ARTICLE
Chenhang Wang, Mingliang Ye
PURPOSE: We compared the adaptive responses to supramaximal high-intensity interval training (HIIT) individualized according to anaerobic speed reserve (ASR), the 30-15 Intermittent Fitness Test (VIFT), and velocity associated with maximum oxygen uptake (MAS) to determine which approach facilitates more identical adaptations across athletes with different profiles. METHODS: Thirty national-level basketball players (age = 28.4 [5] y; body mass = 88.9 [6.3] kg; height = 190 [4...
January 18, 2024: International Journal of Sports Physiology and Performance
https://read.qxmd.com/read/38234738/neuroimaging-markers-of-patient-reported-outcome-measures-in-acute-ischemic-stroke
#34
Lara C Oliveira, Anna K Bonkhoff, Robert W Regenhardt, Kenda Alhadid, Carissa Tuozzo, Mark R Etherton, Natalia S Rost, Markus D Schirmer
OBJECTIVES: To determine the relationship between patient-reported outcome measures (PROMs) and volumetric imaging markers in acute ischemic stroke (AIS). PATIENTS AND METHODS: Patients presenting at Massachusetts General Hospital between February 14, 2017 and February 5, 2020 with a confirmed AIS by MRI were eligible and underwent a telephone interview including PROM-10 questionnaires 3-15 months after stroke. White matter hyperintensity (VWMH ) and brain volumes (VBrain ) were automatically determined using admission clinical MRI...
December 29, 2023: medRxiv
https://read.qxmd.com/read/38224960/impact-of-rapid-sequential-combination-therapy-on-distinct-haemodynamic-measures-in-newly-diagnosed-pulmonary-arterial-hypertension
#35
JOURNAL ARTICLE
Tilmann Kramer, Phillip Nattmann, Felix Gerhardt, Patrycja Stafiej, Daniel Dumitrescu, Henrik Ten Freyhaus, Max Wißmüller, Christopher Hohmann, Stephan Baldus, Stephan Rosenkranz
AIMS: In pulmonary arterial hypertension (PAH), upfront combination therapy with ERA and PDE5i is associated with a reduction in morbidity and mortality events and improves standard haemodynamics, but data remain limited. Aims of this study were (i) to capture detailed haemodynamic effects of rapid sequential dual combination therapy in patients with newly diagnosed PAH; (ii) to monitor the impact of treatment initiation on clinical variables and patients' risk status, and (iii) to compare the treatment effect in patients with 'classical PAH' and 'PAH with co-morbidities'...
January 15, 2024: ESC Heart Failure
https://read.qxmd.com/read/38224539/the-volume-and-the-distribution-of-premorbid-white-matter-hyperintensities-impact-on-post-stroke-aphasia
#36
JOURNAL ARTICLE
Veronika Vadinova, A J Sihvonen, F Wee, K L Garden, L Ziraldo, T Roxbury, K O'Brien, D A Copland, K L McMahon, S L E Brownsett
White matter hyperintensities (WMH) are a radiological manifestation of progressive white matter integrity loss. The total volume and distribution of WMH within the corpus callosum have been associated with pathological cognitive ageing processes but have not been considered in relation to post-stroke aphasia outcomes. We investigated the contribution of both the total volume of WMH, and the extent of WMH lesion load in the corpus callosum to the recovery of language after first-ever stroke. Behavioural and neuroimaging data from individuals (N = 37) with a left-hemisphere stroke were included at the early subacute stage of recovery...
January 2024: Human Brain Mapping
https://read.qxmd.com/read/38216637/lower-body-negative-pressure-identifies-altered-central-vein-characteristics-without-accompanying-changes-to-baroreflexes-in-astronauts-within-hours-of-landing
#37
JOURNAL ARTICLE
C J Mastrandrea, D K Greaves, J K Shoemaker, A P Blaber, P Arbeille, R L Hughson
Cardiovascular deconditioning and altered baroreflexes predispose returning astronauts to Orthostatic Intolerance. We assessed 7 astronauts (1 female) before and following long-duration spaceflight (146 ± 43 days) with minimal upright posture prior to testing. We applied lower body negative pressure (LBNP) of up to - 30 mmHg to supine astronauts instrumented for continual synchronous measurements of cardiovascular variables, and intermittent imaging the Portal Vein (PV) and Inferior Vena Cava (IVC)...
January 12, 2024: Scientific Reports
https://read.qxmd.com/read/38185911/differential-effects-of-mechano-electric-feedback-mechanisms-on-whole-heart-activation-repolarization-and-tension
#38
JOURNAL ARTICLE
Tobias Gerach, Axel Loewe
The human heart is subject to highly variable amounts of strain during day-to-day activities and needs to adapt to a wide range of physiological demands. This adaptation is driven by an autoregulatory loop that includes both electrical and the mechanical components. In particular, mechanical forces are known to feed back into the cardiac electrophysiology system, which can result in pro- and anti-arrhythmic effects. Despite the widespread use of computational modelling and simulation for cardiac electrophysiology research, the majority of in silico experiments ignore this mechano-electric feedback entirely due to the high computational cost associated with solving cardiac mechanics...
January 7, 2024: Journal of Physiology
https://read.qxmd.com/read/38178374/association-between-normal-saline-infusion-volume-in-the-emergency-department-and-acute-kidney-injury-in-heat-stroke-patients-a-multicenter-retrospective-study
#39
MULTICENTER STUDY
Lan Chen, Junlu Zhao, Liyun Lu, Zhumei Gong, Shuying Xu, Xiaoling Yang, Yuping Zhang, Xiuqin Feng
BACKGROUND: Previous studies have shown that intravenous normal saline (NS) may be associated with the incidence of acute kidney injury (AKI). This study aimed to evaluate the association between the volume of NS infusion and AKI in heat stroke (HS) patients. METHODS: This multicenter retrospective cohort study included 138 patients with HS. The primary outcome was the incidence of AKI. Secondary outcomes included the need for continuous renal replacement therapy (CRRT), admission to the intensive care unit (ICU), length of stay in the ICU and hospital, and in-hospital mortality...
December 2024: Renal Failure
https://read.qxmd.com/read/38170290/three-year-incidence-and-acute-setting-predictors-of-epilepsy-after-neonatal-and-childhood-arterial-ischaemic-stroke-a-disease-based-cohort-study
#40
JOURNAL ARTICLE
Mauricio Lopez-Espejo, Ilona Skorin, Tomas Mesa, Marta I Hernandez-Chavez
UNLABELLED: To assess the association between clinical and MRI characteristics of arterial ischaemic stroke (AIS) and the 3-year risk of post-stroke epilepsy (PSE) in paediatric patients. Retrospective cohort study. Database from a single tertiary referral centre for paediatric stroke in Chile. Two hundred seven neonates and children (1 day to 18 years) with a first-ever supratentorial AIS diagnosed between January 2003 and December 2019 were evaluated. Diagnosis of PSE and explanatory variables were consecutively recorded from hospital inpatient and annual outpatient records in a predesigned database...
January 3, 2024: European Journal of Pediatrics
keyword
keyword
164962
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.