Johanna Maria Ospel, Leon Rinkel, Aravind Ganesh, Andrew Demchuk, Manish Joshi, Alexandre Poppe, Ryan McTaggart, Raul Nogueira, Bijoy Menon, Michael Tymianski, Michael Douglas Hill, Mayank Goyal
BACKGROUND: To assess the association of qualitative and quantitative infarct characteristics and 3 cognitive outcome tests, namely the Montreal Cognitive Assessment (MOCA) for mild cognitive impairment, the Boston Naming Test for visual confrontation naming, and the Sunnybrook Neglect Assessment Procedure for neglect, in large vessel occlusion stroke. METHODS: Secondary observational cohort study using data from the randomized-controlled ESCAPE-NA1 trial (Safety and Efficacy of Nerinetide in Subjects Undergoing Endovascular Thrombectomy for Stroke), in which patients with large vessel occlusion undergoing endovascular treatment were randomized to receive either intravenous Nerinetide or placebo...
March 21, 2024: Stroke; a Journal of Cerebral Circulation