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REVIEW
Nimra Hasnain, Taha Bin Arif, Roha Shafaut, Faiza Zakaria, Syeda Zainab Fatima, Ibtehaj Ul Haque
Huntington's disease is a rare autosomal dominant disorder presenting with chorea, rigidity, hypo-/akinesia, cognitive decline, and psychiatric disturbances. Numerous risk factors have been defined in the onset of this disease. However, the number of CAG repeats in the genes are the most crucial factor rendering patients susceptible to the disease. Studies have shown significant differences in onset and disease presentation among the sexes, which prompts analysis of the impact of different sexes on disease etiology and progression...
June 20, 2022: Wiener Medizinische Wochenschrift
#22
JOURNAL ARTICLE
Tiffany Barkley, Roha Khalid, Mukta Sharma, Ashley Sherman, Jennifer Flint
Objective: To assess the demographics and clinical characteristics of children presenting with acute neurologic symptoms concerning for stroke. Background: Stroke leads to significant morbidity in the pediatric population. Stroke protocols were created as a means to help identify and triage these children. Despite implementation of these protocols, there have been few population-based studies evaluating the demographics and clinical features of children presenting with acute strokelike symptoms. Methods: A retrospective chart review of patients for whom the stroke alert process was activated from September 2016 through August 2018 at Children's Mercy Hospital...
April 2022: Journal of Child Neurology
#23
JOURNAL ARTICLE
Roha M Kaipa, Ramesh Kaipa, Alice Keithly
PURPOSE: The purpose of the current study was to investigate the lag effects in two different versions of distributed practice on learning novel language vocabulary. METHOD: Forty-four healthy monolingual English-speaking participants were randomly assigned to two versions of distributed practice. The two versions of distributed practice were created by altering the temporal lag between the practice sessions. Participants in both groups completed a similar practice regimen wherein they practiced 30 French occupations five times each for a total of 150 times...
January 12, 2022: Logopedics, Phoniatrics, Vocology
#24
JOURNAL ARTICLE
Muhammad Kashif, Iayla Fatima, Abdul Moiz Ahmed, Shajeea Arshad Ali, Roha Saeed Memon, Muhammad Afzal, Usama Saeed, Sana Gul, Junaid Ahmad, Farheen Malik, Mehreen Malik, Jawad Ahmed
Background Vaccine hesitancy has been a huge challenge in controlling preventable diseases. With the emergence of coronavirus disease 2019 (COVID-19) vaccines, it is vital to know their acceptance rates among the masses. No comparative data is available on the current subject from Pakistan yet. Therefore, this study aimed to evaluate the acceptance of a potential COVID-19 vaccine among the general population and healthcare workers (HCWs) of Pakistan, along with their perceptions and barriers to acceptance. Methods An online cross-sectional study was carried out in Pakistan from December 19, 2020, to January 10, 2021, using convenience sampling...
October 2021: Curēus
#25
JOURNAL ARTICLE
Konstantinos N Fountoulakis, Grigorios Karakatsoulis, Seri Abraham, Kristina Adorjan, Helal Uddin Ahmed, Renato D Alarcón, Kiyomi Arai, Sani Salihu Auwal, Michael Berk, Sarah Bjedov, Julio Bobes, Teresa Bobes-Bascaran, Julie Bourgin-Duchesnay, Cristina Ana Bredicean, Laurynas Bukelskis, Akaki Burkadze, Indira Indiana Cabrera Abud, Ruby Castilla-Puentes, Marcelo Cetkovich, Hector Colon-Rivera, Ricardo Corral, Carla Cortez-Vergara, Piirika Crepin, Domenico De Berardis, Sergio Zamora Delgado, David De Lucena, Avinash De Sousa, Ramona Di Stefano, Seetal Dodd, Livia Priyanka Elek, Anna Elissa, Berta Erdelyi-Hamza, Gamze Erzin, Martin J Etchevers, Peter Falkai, Adriana Farcas, Ilya Fedotov, Viktoriia Filatova, Nikolaos K Fountoulakis, Iryna Frankova, Francesco Franza, Pedro Frias, Tatiana Galako, Cristian J Garay, Leticia Garcia-Álvarez, Maria Paz García-Portilla, Xenia Gonda, Tomasz M Gondek, Daniela Morera González, Hilary Gould, Paolo Grandinetti, Arturo Grau, Violeta Groudeva, Michal Hagin, Takayuki Harada, M Tasdik Hasan, Nurul Azreen Hashim, Jan Hilbig, Sahadat Hossain, Rossitza Iakimova, Mona Ibrahim, Felicia Iftene, Yulia Ignatenko, Matias Irarrazaval, Zaliha Ismail, Jamila Ismayilova, Asaf Jacobs, Miro Jakovljević, Nenad Jakšić, Afzal Javed, Helin Yilmaz Kafali, Sagar Karia, Olga Kazakova, Doaa Khalifa, Olena Khaustova, Steve Koh, Svetlana Kopishinskaia, Korneliia Kosenko, Sotirios A Koupidis, Illes Kovacs, Barbara Kulig, Alisha Lalljee, Justine Liewig, Abdul Majid, Evgeniia Malashonkova, Khamelia Malik, Najma Iqbal Malik, Gulay Mammadzada, Bilvesh Mandalia, Donatella Marazziti, Darko Marčinko, Stephanie Martinez, Eimantas Matiekus, Gabriela Mejia, Roha Saeed Memon, Xarah Elenne Meza Martínez, Dalia Mickevičiūtė, Roumen Milev, Muftau Mohammed, Alejandro Molina-López, Petr Morozov, Nuru Suleiman Muhammad, Filip Mustač, Mika S Naor, Amira Nassieb, Alvydas Navickas, Tarek Okasha, Milena Pandova, Anca-Livia Panfil, Liliya Panteleeva, Ion Papava, Mikaella E Patsali, Alexey Pavlichenko, Bojana Pejuskovic, Mariana Pinto Da Costa, Mikhail Popkov, Dina Popovic, Nor Jannah Nasution Raduan, Francisca Vargas Ramírez, Elmars Rancans, Salmi Razali, Federico Rebok, Anna Rewekant, Elena Ninoska Reyes Flores, María Teresa Rivera-Encinas, Pilar Saiz, Manuel Sánchez de Carmona, David Saucedo Martínez, Jo Anne Saw, Görkem Saygili, Patricia Schneidereit, Bhumika Shah, Tomohiro Shirasaka, Ketevan Silagadze, Satti Sitanggang, Oleg Skugarevsky, Anna Spikina, Sridevi Sira Mahalingappa, Maria Stoyanova, Anna Szczegielniak, Simona Claudia Tamasan, Giuseppe Tavormina, Maurilio Giuseppe Maria Tavormina, Pavlos N Theodorakis, Mauricio Tohen, Eva Maria Tsapakis, Dina Tukhvatullina, Irfan Ullah, Ratnaraj Vaidya, Johann M Vega-Dienstmaier, Jelena Vrublevska, Olivera Vukovic, Olga Vysotska, Natalia Widiasih, Anna Yashikhina, Panagiotis E Prezerakos, Daria Smirnova
INTRODUCTION: There are few published empirical data on the effects of COVID-19 on mental health, and until now, there is no large international study. MATERIAL AND METHODS: During the COVID-19 pandemic, an online questionnaire gathered data from 55,589 participants from 40 countries (64.85% females aged 35.80 ± 13.61; 34.05% males aged 34.90±13.29 and 1.10% other aged 31.64±13.15). Distress and probable depression were identified with the use of a previously developed cut-off and algorithm respectively...
January 2022: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
#26
JOURNAL ARTICLE
Roha Saeed Memon, Irfan Ullah, Sheikh Shoib, Qudrat Ullah Qudrat, Renato de Filippis
The COVID-19 pandemic brought with itself significant mental health challenges owing not only to the morbidity and mortality from the infection but also to mitigation strategies of social distancing and self-isolation. Indeed, in the absence of adequate pharmaceutical aids, quarantine and social distancing measures are taken to limit the spread of the SARS-CoV-2 virus. Thus, living in the world of social media, the average usage of social media could be expected to show a sharp rise as measures of social distancing and quarantine are adopted to contain the pandemic...
September 1, 2021: Journal of Nervous and Mental Disease
#27
JOURNAL ARTICLE
Muhammad Waqas, Ali Haider, Abdur Rehman, Muhammad Qasim, Ahitsham Umar, Muhammad Sufyan, Hafiza Nisha Akram, Asif Mir, Roha Razzaq, Danish Rasool, Rana Adnan Tahir, Sheikh Arslan Sehgal
BACKGROUND: Coronaviruses (CoVs) are enveloped positive-strand RNA viruses which have club-like spikes at the surface with a unique replication process. Coronaviruses are categorized as major pathogenic viruses causing a variety of diseases in birds and mammals including humans (lethal respiratory dysfunctions). Nowadays, a new strain of coronaviruses is identified and named as SARS-CoV-2. Multiple cases of SARS-CoV-2 attacks are being reported all over the world. SARS-CoV-2 showed high death rate; however, no specific treatment is available against SARS-CoV-2...
2021: BioMed Research International
#28
COMPARATIVE STUDY
Juan Alonso Leon-Abarca, Roha Saeed Memon, Bahar Rehan, Maimoona Iftikhar, Antara Chatterjee
BACKGROUND: The spectrum of pre-existing renal disease is known as a risk factor for severe COVID-19 outcomes. However, little is known about the impact of COVID-19 on patients with diabetic nephropathy in comparison to patients with chronic kidney disease. METHODS: We used the Mexican Open Registry of COVID-19 patients 11 to analyze anonymized records of those who had symptoms related to COVID-19 to analyze the rates of SARS-CoV-2 infection, development of COVID-19 pneumonia, admission, intubation, Intensive Care Unit admission and mortality...
November 10, 2020: Acta Bio-medica: Atenei Parmensis
#29
REVIEW
Maryam Zaman, Roha Saeed Memon, Arooba Amjad, Tehlil Rizwan, Jai Kumar, Ibtehaj Ul Haque, Syed Saad Ali, Lin Li, Muhammad Shariq Usman
PURPOSE: To conduct a meta-analysis to evaluate the effect of ertugliflozin on long-term hemoglobin A1c (HbA1c), body weight and blood pressure (BP). METHODS: Online databases available were searched from their inception to February 2020. Randomized controlled trials (RCTs) comparing ertugliflozin to either placebo or an active control drug were included. Data on four efficacy outcomes were extracted, namely: HbA1c, systolic blood pressure (SBP), diastolic blood pressure (DBP) and body weight...
December 2020: Journal of Diabetes and Metabolic Disorders
#30
JOURNAL ARTICLE
Javeria Saquib, Farea Ahmed, Roha Saeed Memon
No abstract text is available yet for this article.
January 2021: JPMA. the Journal of the Pakistan Medical Association
#31
JOURNAL ARTICLE
Tomáš Rohá
Kidney transplantation is the first-choice treatment of the end-stage kidney disease. By increasing the number of kidney transplants and by improving the care for these patients, there is increasing number of patients with a functional graft, who need adequate follow-up and treatment. It is advisable to feasibly transfer some portion of the care to the doctors based outside transplant centres and so it is necessary to make them familiar with these issues. That is also the purpose of this article, which is focused on some of those frequent medical problems associated with kidney transplantations, which are in competence of internal medicine doctors...
2020: Vnitr̆ní Lékar̆ství
#32
JOURNAL ARTICLE
Jai Kumar, Roha Saeed Memon, Izza Shahid, Tehlil Rizwan, Maryam Zaman, Ritesh G Menezes, Sarwan Kumar, Tariq Jamal Siddiqi, Muhammad Shariq Usman
BACKGROUND: The efficacy of antidiabetic agents for the treatment of non-alcoholic fatty liver disease (NAFLD) remains unclear. AIM: To conduct a meta-analysis to study the efficacy of pioglitazone and three novel anti-diabetic agents: glucagon-like peptide-1 (GLP-1) agonists, sodium-glucose co-transporter-2 (SGLT2) inhibitors, and dipeptidyl-peptidase-4 (DPP4) inhibitors in treating NAFLD. METHODS: Online databases were searched in May 2020 for randomized clinical trials...
January 2021: Digestive and Liver Disease
#33
JOURNAL ARTICLE
Florencia Moreno, Adriana Rose, M Agustina Chaplin, M Cristina Cipolla, Mercedes García Lombardi, Mariana Nana, Guillermo Cervio, Esteban Halac, Marianela Viso, Victor Ayarzabal, Andrea Bosaleh, Daniel Liberto, Elena Sarabia, Ana Rizzi, Mercedes Morici, Patricia Streitenberger, María Teresa G de Dávila
BACKGROUND: Information on the epidemiology of pediatric liver tumors in Latin America is limited. PURPOSE: To describe the incidence of liver tumors in a pediatric registry in Argentina according to geographic region, national trends over 16 years, and survival related to stage, age, sex, and care center. METHODS: Newly diagnosed liver tumors cases are registered in the Argentine Pediatric Oncology Hospital Registry (ROHA) with an estimated coverage of 91% of national cases...
November 2020: Pediatric Blood & Cancer
#34
JOURNAL ARTICLE
Marium Zafar, Muhammad Mussa, Roha S Memon, Shahrukh Nadeem, Muhammad S Usman, Javed Siddiqi, Alexander Norbash, Faisal Khosa, Vincent M Figueredo, Richard Krasuski, Muhammad S Khan
Introduction This meta-analysis was conducted to assess the safety and efficacy of aspiration thrombectomy versus stent retriever thrombectomy for acute ischemic stroke (AIS). Methods We queried online databases for original studies comparing aspiration thrombectomy with stent retriever thrombectomy in patients with AIS. After article selection, data were extracted on multiple baseline characteristics and prespecified endpoints. Dichotomous data were presented as risk ratios (RRs) and corresponding 95% confidence intervals (CIs); continuous data as mean differences and 95% CIs...
May 31, 2020: Curēus
#35
JOURNAL ARTICLE
Ya-Ting Hsu, Yu-Chu Wang, Ruo-Yu Chen, Liang-Yi Hung, Sin-Syue Li, Chi-Chieh Yen, Tsai-Yun Chen, L Jeffrey Medeiros, Kung-Chao Chang
Angioimmunoblastic T-cell lymphoma (AITL) carries genetic mutations of TET2 , RHOA , and IDH2 , but the prognostic impact of these mutations is not widely investigated. Although one study shows no difference in overall survival between patients with or without RHOA G17V mutation, a poor performance status is associated with RHOA G17V-mutated AITL, which is an independent adverse factor. We retrospectively investigated the prognostic impact of RHOA G17V mutation in AITL patients. A total of 31 cases were enrolled (male-to-female, 2...
May 2020: Leukemia & Lymphoma
#36
JOURNAL ARTICLE
Roha Khalid, Mohammed Ilyas, Ahmed Abdelmoity
No abstract text is available yet for this article.
October 9, 2019: Journal of Pediatrics
#37
JOURNAL ARTICLE
Hao Li, Jun Yao, Robert Duran, Beenish Roha, Nuray Karapınar, Gyozo Jordan, Tatiana Minkina, Jihai Gu, Chao Lu, Ning Min, Zixia Fan
The combined toxicological effects of nickel (Ni) and butyl xanthate (BX), that is commonly used in flotation reagents for non-ferrous metals ore processing such as Ni, copper and lead ores, on soil microbial communities were studied by determining soil microbial activity, soil enzyme activities and Ni bioavailability. The results revealed that the exchangeable (EXC) and reducible (RED) fractions of Ni were higher in Ni/BX mixture than Ni alone, probably because BX reacts with Ni to form complexes that lead an increase in bioavailability of Ni...
February 2020: Chemosphere
#38
JOURNAL ARTICLE
Marium Zafar, Roha Saeed Memon, Muhammad Mussa, Rameez Merchant, Aiman Khurshid, Faisal Khosa
This meta-analysis was conducted to assess the safety and efficacy of sonothrombolysis along with intravenous recombinant tissue plasminogen activator, alteplase (IV rtPA), in the management of acute ischemic stroke. Electronic databases were searched under different meSH terms without the restriction of time and language. 1415 studies were analyzed and seven studies that matched the inclusion criteria were selected. Multiple safety and efficacy outcomes were extracted. Our pooled analysis demonstrated that there is no significant difference between sonothrombolysis group and control group in preventing mortality (RR 1...
August 2019: Journal of Thrombosis and Thrombolysis
#39
COMPARATIVE STUDY
Nav Persaud, Maggie Jiang, Roha Shaikh, Anjli Bali, Efosa Oronsaye, Hannah Woods, Gregory Drozdzal, Yathavan Rajakulasingam, Darshanand Maraj, Sapna Wadhawan, Norman Umali, Ri Wang, Marcy McCall, Jeffrey K Aronson, Annette Plüddemann, Lorenzo Moja, Nicola Magrini, Carl Heneghan
OBJECTIVE: To compare the medicines included in national essential medicines lists with the World Health Organization's (WHO's) Model list of essential medicines , and assess the extent to which countries' characteristics, such as WHO region, size and health care expenditure, account for the differences. METHODS: We searched the WHO's Essential Medicines and Health Products Information Portal for national essential medicines lists. We compared each national list of essential medicines with both the 2017 WHO model list and other national lists...
June 1, 2019: Bulletin of the World Health Organization
#40
JOURNAL ARTICLE
Rabbia Siddiqi, Roha Saeed Memon, Hassan Ahmed
No abstract text is available yet for this article.
June 2019: JPMA. the Journal of the Pakistan Medical Association
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