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Mahrukh Muhammad Ali, Roha Saeed Memon, Marium Zafar
No abstract text is available yet for this article.
October 2018: JPMA. the Journal of the Pakistan Medical Association
Suhaira Bilquees, Roha Saeed Memon, Muhammad Arbaz Arshad Khan
No abstract text is available yet for this article.
October 2018: JPMA. the Journal of the Pakistan Medical Association
Jihai Gu, Jun Yao, Gyozo Jordan, Beenish Roha, Ning Min, Hao Li, Chao Lu
Toxic metal(loid)s released from tailing residues of mining operations have become a global issue with regard to environmental impacts. Biochar derived from the agriculture waste is considered as a cost-effective and stable material, which could be applied for remediation of sites contaminated with toxic metal(loid)s. In the present study, tailings were amended for 90 days with increasing concentrations of Arundo donax L. stem-derived biochar (ASBC; at 0, 1, 3, and 5%). The 7-day wheat seed germination toxicity test was then used to assess the bioavailability of toxicants in aqueous leachates of the biochar-amended tailing samples...
August 18, 2018: Environmental Science and Pollution Research International
Hao Li, Jun Yao, Jihai Gu, Robert Duran, Beenish Roha, Gyozo Jordan, Jianli Liu, Ning Min, Chao Lu
In non-ferrous metal tailings, combined pollution in the surrounding soil is caused by heavy metals and flotation chemicals. The combined effects of nickel (Ni) and its primary ore processing collector, sodium butyl xanthate (SBX), on soil microbial activity were investigated following the fluorescein diacetate hydrolase (FDA) and sucrase (SA) activities, and isothermal microcalorimetry during 60 days. FDA and SA activities as well as overall soil microbial activity were significantly affected by Ni, SBX and Ni/SBX mixture...
November 15, 2018: Ecotoxicology and Environmental Safety
Roha Khalid, Pradeep Krishnan, Kathleen Andres, Susan Blaser, Steven Miller, Mahendranath Moharir, Nomazulu Dlamini
No abstract text is available yet for this article.
January 30, 2018: Neurology
Alexandra Huttinger, Laura Brunson, Christine L Moe, Kristin Roha, Providence Ngirimpuhwe, Leodomir Mfura, Felix Kayigamba, Philbert Ciza, Robert Dreibelbis
Small water enterprises (SWEs) have lower capital expenditures than centralized systems, offering decentralized solutions for rural markets. This study evaluated SWEs in rural Rwanda, where nine health care facilities (HCF) owned and operated water kiosks supplying water from onsite water treatment systems (WTS). SWEs were monitored for 12 months. Spearman's Rank Correlation Coefficient (rs ) was used to evaluate correlations between demand for kiosk water and community characteristics, and between kiosk profit and factors influencing the cost model...
December 16, 2017: International Journal of Environmental Research and Public Health
Sharif Hashmani, Nauman Hashmani, Roha Saeed Memon
We present here the case of a 24-year-old male who experienced progressive keratoconus and vision loss which adversely affected his ability to carry out everyday tasks. This landed him in the Hashmanis Hospital for consultation. He had a preoperative best corrected visual acuity of 6/12. He underwent multiple Oculus Pentacam examinations, which showed progressive keratoconus. Corneal collagen cross-linking (CXL) was performed to stabilize his cornea and, subsequently, an Artiflex anterior chamber iris-fixated phakic intraocular lens (ACIF-PIOL) was implanted to alleviate his refractive errors...
September 2017: Case Reports in Ophthalmology
Ramesh Kaipa, Roha Mariam Kaipa
PURPOSE: The role of principles of motor learning (PMLs) in speech has received much attention in the past decade. Oral motor learning, however, has not received similar consideration. This study evaluated the role of three practice conditions in an oral motor tracking task. METHOD: Forty-five healthy adult participants were randomly and equally assigned to one of three practice conditions (constant, blocked, and random) and participated in an electromyography-based task...
October 19, 2017: Journal of Motor Behavior
Asim Shaikh, Hamza T Ansari, Zeerak Ahmad, Mahnoor Y Shaikh, Ilma Khalid, Maha Jahangir, Amna Majeed, Nimra Shakeel, Arsalan Ahmed, Roha Saeed Memon, Eleze Tariq, Rafia Irfan, Dania Madni
Introduction Studies have shown that electronic cigarettes have gained immense popularity and their use has increased dramatically all over the world. However, little is known about the knowledge and attitudes towards e-cigarettes in third world countries such as Pakistan. The aim of this study was to determine the perceptions of teenagers in Karachi regarding e-cigarettes and whether the differences in said perceptions were affected by gender and level of education. Methods We conducted a cross-sectional study in January 2017 using convenience sampling and interviewed 441 young individuals, aged 13 to 19 years, to determine their knowledge, attitudes, and practices regarding e-cigarettes...
July 13, 2017: Curēus
F Moreno, W Cacciavillano, M Cipolla, M Coirini, P Streitenberger, J López Martí, M Palladino, M Morici, M Onoratelli, G Drago, A Schifino, M Cores, A Rose, J Jotomliansky, M Varel, M García Lombardi
BACKGROUND: Differences in incidence and survival in osteosarcoma reports are considerable worldwide. PURPOSE: This study describes the incidence and survival of patients with osteosarcoma in Argentina with data from the National Pediatric Cancer Registry (ROHA), and the impact of age, gender, stage, regional, and socioeconomic indicators on outcome. METHODS: Pediatric patients with osteosarcoma reported to ROHA from 2000 through 2013 were analyzed, the annual age-standardized incidence rate (ASR) was calculated using the National Vital Statistics, and survival was estimated...
October 2017: Pediatric Blood & Cancer
Zehra Jamil, Syeda Sadia Fatima, Zahra Cheema, Safia Baig, Roha Ahmed Choudhary
BACKGROUND: This study aimed to evaluate the strength of anti-Mullerian hormone (AMH) and follicle stimulating hormone (FSH) in reflecting the antral follicle count (AFC) in infertile females. MATERIALS AND METHODS: This cross-sectional study was conducted on 160 females, visiting infertility clinic for assisted reproduction. Serum samples collected on the 3(rd) day of the cycle were assayed for FSH, luteinizing hormone, and AMH while AFC was assessed via transvaginal ultrasound...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
Xin Chen, Qiu-Shuang Wu, Fan-Cheng Meng, Zheng-Hai Tang, Xiuping Chen, Li-Gen Lin, Ping Chen, Wen-An Qiang, Yi-Tao Wang, Qing-Wen Zhang, Jin-Jian Lu
BACKGROUND: Panacis Japonici Rhizoma (PJR) is one of the most famous Chinese medical herbs that is known for exhibiting potential anti-cancer effects. PURPOSE: This study aims to isolate and investigate the anti-cancer potential of saponins from PJR in ovarian cancer cells. METHODS: The compounds were separated by comprehensive chromatographic methods. By comparison of the 1H- and 13C NMR data, as well as the HR-ESI-MS data, with the corresponding references, the structures of compounds were determined...
December 1, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
Qingling Huang, Valentina E Schneeberger, Noreen Luetteke, Chengliu Jin, Roha Afzal, Mikalai M Budzevich, Rikesh J Makanji, Gary V Martinez, Tao Shen, Lichao Zhao, Kar-Ming Fung, Eric B Haura, Domenico Coppola, Jie Wu
RET fusions have been found in lung adenocarcinoma, of which KIF5B-RET is the most prevalent. We established inducible KIF5B-RET transgenic mice and KIF5B-RET-dependent cell lines for preclinical modeling of KIF5B-RET-associated lung adenocarcinoma. Doxycycline-induced CCSP-rtTA/tetO-KIF5B-RET transgenic mice developed invasive lung adenocarcinoma with desmoplastic reaction. Tumors regressed upon suppression of KIF5B-RET expression. By culturing KIF5B-RET-dependent BaF3 (B/KR) cells with increasing concentrations of cabozantinib or vandetanib, we identified cabozantinib-resistant RETV804L mutation and vandetanib-resistant-RETG810A mutation...
October 2016: Molecular Cancer Therapeutics
Young Sook Roha, Eun Ju Lima, S Barry Issenberg
BACKGROUND: This study evaluates the effectiveness of integrated simulation-based resuscitation skills training combined with a clinical practicum by assessing nursing students' knowledge, psychomotor skills, and self-efficacy. METHODS: In a pretest-posttest design, 255 second-year nursing students participated in an emergency nursing clinical course consisting of a two-hour simulation-based resuscitation skills training component along with an 80-hour clinical placement in an emergency department...
2016: Collegian: Journal of the Royal College of Nursing, Australia
Vandana Shashi, Slavé Petrovski, Kelly Schoch, Rebecca Crimian, Laura E Case, Roha Khalid, Maysantoine A El-Dairi, Yong-Hui Jiang, Mohamad A Mikati, David B Goldstein
One of the most promising outcomes of whole-exome sequencing (WES) is the alteration of medical management following an accurate diagnosis in patients with previously unresolved disorders. Although case reports of targeted therapies resulting from WES have been published, there are few reports with long-term follow-up that confirm a sustained therapeutic response. Following a diagnosis by WES of Brown-Vialetto-Van Laere Syndrome 2 (BVVLS2), high-dose riboflavin therapy was instituted in a 20-mo-old child. An immediate clinical response with stabilization of signs and symptoms was noted over the first 2-4 wk...
October 2015: Cold Spring Harbor Molecular Case Studies
Slavé Petrovski, Vandana Shashi, Steven Petrou, Kelly Schoch, Keisha Melodi McSweeney, Ryan S Dhindsa, Brian Krueger, Rebecca Crimian, Laura E Case, Roha Khalid, Maysantoine A El-Dairi, Yong-Hui Jiang, Mohamad A Mikati, David B Goldstein
Genetically targeted therapies for rare Mendelian conditions are improving patient outcomes. Here, we present the case of a 20-mo-old female suffering from a rapidly progressing neurological disorder. Although diagnosed initially with a possible autoimmune condition, analysis of the child's exome resulted in a diagnosis of Brown-Vialetto-Van Laere syndrome 2 (BVVLS2). This new diagnosis led to a change in the therapy plan from steroids and precautionary chemotherapy to high-dose riboflavin. Improvements were reported quickly, including in motor strength after 1 mo...
October 2015: Cold Spring Harbor Molecular Case Studies
Florencia Moreno, Jessica Lopez Marti, Marcela Palladino, Pablo Lobos, Ariel Gualtieri, Walter Cacciavillano
BACKGROUND: There are reports indicating a low incidence of neuroblastoma (NB) in some developing countries but no conclusive data are available from population-based studies at a national level. PURPOSE: To describe the incidence and survival of 971 patients with NB in Argentina with data from the National Pediatric Cancer Registry (ROHA), and the impact of age, gender, stage, regional, and socioeconomic indicators on outcome. METHODS: All cases of NB reported to ROHA (2000-2012) were the subject of the analysis...
August 2016: Pediatric Blood & Cancer
Hong Zheng, Weipeng Zhao, Cihui Yan, Crystina C Watson, Michael Massengill, Mengyu Xie, Chris Massengill, David R Noyes, Gary V Martinez, Roha Afzal, Zhihua Chen, Xiubao Ren, Scott J Antonia, Eric B Haura, Brian Ruffell, Amer A Beg
PURPOSE: A significant limitation of checkpoint blockade immunotherapy is the relatively low response rate (e.g., ∼20% with PD-1 blockade in lung cancer). In this study, we tested whether strategies that increase T-cell infiltration to tumors can be efficacious in enhancing immunotherapy response. EXPERIMENTAL DESIGN: We performed an unbiased screen to identify FDA-approved oncology agents with an ability to enhance T-cell chemokine expression with the goal of identifying agents capable of augmenting immunotherapy response...
August 15, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Alexandra Huttinger, Robert Dreibelbis, Kristin Roha, Fidel Ngabo, Felix Kayigamba, Leodomir Mfura, Christine Moe
There is a critical need for safe water in healthcare facilities (HCF) in low-income countries. HCF rely on water supplies that may require additional on-site treatment, and need sustainable technologies that can deliver sufficient quantities of water. Water treatment systems (WTS) that utilize ultrafiltration membranes for water treatment can be a useful technology in low-income countries, but studies have not systematically examined the feasibility of this technology in low-income settings. We monitored 22 months of operation of 10 WTS, including pre-filtration, membrane ultrafiltration, and chlorine residual disinfection that were donated to and operated by rural HCF in Rwanda...
October 2015: International Journal of Environmental Research and Public Health
Roha M Thomas, Ramesh Kaipa, Attigodu Chandrashekara Ganesh
OBJECTIVES: The current study aimed to compare the auditory interference control of participants with Learning Disability (LD) to a control group on two versions of an auditory Stroop task. METHODS: A group of eight children with LD (clinical group) and another group of eight typically developing children (control group) served as participants. All the participants were involved in a semantic and a gender identification-based auditory Stroop task. Each participant was presented with eight different words (10 times) that were pre-recorded by a male and a female speaker...
December 2015: International Journal of Pediatric Otorhinolaryngology
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