Chang Shu, Yadong Chen, Zhenzhen Zhang, Yuqing Lei, Jiajia Xu, Weiwei Lao, Qingping Xi, Qiang Sun, Xiaojun Li, Hongbing Liao, Qiaojie Luo, Xiaodong Li
Structural degeneration of a hybrid layer composed of a demineralized dentin matrix (DDM) and adhesive causes unsatisfactory functional outcomes in terms of bonding repair and caries treatment and is accompanied by high prevalence of secondary caries. Clinically, defects in the hybrid layer from insufficient adhesive infiltration, bacterial load from retained infected-dentin, and bacterial attack from the oral cavity are the main threats to degeneration. Currently, there is no strategy to simultaneously address adhesive penetration and bacterial infection...
November 7, 2023: Journal of Materials Chemistry. B, Materials for Biology and Medicine