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27 years old

Thaís Dos Reis Vilela, Marina Monzani da Rocha, Neliana Buzi Figlie, Jair de Jesus Mari
BACKGROUND: Children exposed to substance use in their families are vulnerable to multiple risk factors in their development and at increased risk for emotional and behavioral problems. The aims of the study were as follows 1) estimate the prevalence of emotional and behavioral problems among children aged 6-11 years old, living with addicted family members in a low-income urban community of São Paulo, Southeastern Brazil; 2) evaluate the children's exposure to family psychosocial stressors and substance use; and 3) investigate the factors related to the increased risk of emotional and behavioral problems and substance use...
March 19, 2019: Child Abuse & Neglect
Balasingam Balagobi, Kalhar Indika, W Muditha C K Samaraweera, K Suranga N Wijayarathna, Hansika P Maddumage, Kugadas Sutharshan, Swarna Suvendran, Anuruddha M Abeygunasekera
Background: Associated risk factors for renal cell carcinoma (RCC) include smoking, obesity, hypertension, and diabetes mellitus (DM). Studies on their role in Sri Lankan patients are sparse. The aims were to determine the risk factors for RCC in a cohort of Sri Lankan patients. Methods: A hospital-based case-control study was done in a teaching hospital from January 1, 2009, to December 31, 2015. The prospectively collected data included history of smoking, hypertension, DM, and body mass index (BMI)...
March 2019: Journal of Cancer Research and Therapeutics
Margie K Olds, Richard Ellis, Priya Parmar, Paula Kersten
Objective: To develop a multivariate tool that would predict recurrent instability after a first-time traumatic anterior shoulder dislocation. Methods: Participants (aged 16-40 years) were recruited across New Zealand into a prospective cohort study. Baseline data were collected during a telephone interview and through examination of radiology records. Variables associated with recurrent instability were selected for the multivariate logistic regression model using backwards selection (p<0...
2019: BMJ Open Sport & Exercise Medicine
Mukharram M Bikbov, Rinat R Fayzrakhmanov, Gyulli M Kazakbaeva, Rinat M Zainullin, Venera F Salavatova, Timur R Gilmanshin, Inga I Arslangareeva, Nikolai A Nikitin, Songhomitra Panda-Jonas, Svetlana R Mukhamadieva, Dilya F Yakupova, Renat I Khikmatullin, Said K Aminev, Ildar F Nuriev, Artur F Zaynetdinov, Yulia V Uzianbaeva, Jost B Jonas
OBJECTIVE: With data on frequency of hearing loss in Russia and Eastern Europe generally lacking, we assessed the prevalence of hearing loss in a Russian population. SETTING: The population-based Ural Eye and Medical Study was conducted in the rural and urban regions of Bashkortostan, Russia. PARTICIPANTS: With an inclusion criterion of age 40+ years, the study included 5899 (80.5%) out of 7328 eligible individuals (mean age: 59.0±10.7 years; range: 40-94 years)...
March 20, 2019: BMJ Open
Adriana Gonzalez, Amit M Saindane, Stewart Neil, Nelson M Oyesiku, Adriana G Ioachimescu
BACKGROUND: When distinct pituitary hypersecretory manifestations coexist, the differential diagnosis includes plurihormonal or double pituitary adenomas. We describe a rare case of hypercortisolemia and hyperprolactinemia caused by two non-contiguous adenomas that required two surgeries. CASE PRESENTATION: A 37-year-old woman presented with 6-month of weight gain, amenorrhea, joint pain, leg swelling and skin changes. She received prednisone for possible systemic lupus erythematosus...
March 18, 2019: World Neurosurgery
Borys M Kwinta, Kornelia M Kliś, Roger M Krzyżewski, Aleksander Wilk, Marcin Dragan, Ewelina Grzywna, Tadeusz Popiela
BACKGROUND: The number of elderly patients with unruptured intracranial aneurysms is increasing with time in aging populations; however the choice of the proper treatment method remains inconclusive. The goal of the study is to evaluate the possible complications and treatment outcome among elderly patients with unruptured intracranial aneurysm. METHODS: We have retrospectively analysed 139 patients above 65 years old, hospitalized between 2007 and 2017 in the high-volume neurosurgical centre and diagnosed with unruptured intracranial aneurysm...
March 18, 2019: World Neurosurgery
Y Y Chi, Q F Song, S L Wu, S H Chen, X Z Wang
Objective: To investigate the association between sleep duration and brachial-ankle pulse wave velocity (baPWV). Methods: A cross-sectional study method was used to observe 38 604 employees of Kailuan Group who participated in the physical examination and the baPWV test from January 2010 to July 2018. The age was (51.6±11.1) years old. There were 72.4% (27 955/38 604) male participants. According to the sleep duration, subjects were divided into 5 groups including ≤ 5 hours group (3 762 cases),>5 hours and ≤6 hours group (9 585 cases),>6 hours and ≤7 hours group (12 604 cases), >7 hours and ≤8 hours group (11 921 cases) and >8 hours group (732 cases)...
March 24, 2019: Zhonghua Xin Xue Guan Bing za Zhi
F W Jia, F F Wang, J J Xu, X H Liu, H Y Pang, X Lin, L G Fang, W Chen
Objective: To observe the relationship between impaired myocardial untwisting and left ventricular diastolic dysfunction in patients with autoimmune diseases (AD). Methods: In this retrospective study, 95 AD patients (27 males, (38.6±14.2) years old) were enrolled as AD group and 71 gender and age matched healthy subjects (24 males, (37.6±12.2) years old) were enrolled as control group, all underwent transthoracic echocardiography and two-dimensional speckle-tracking echocardiography (STE) in our hospital between January 2014 and June 2018...
March 24, 2019: Zhonghua Xin Xue Guan Bing za Zhi
Shinichi Wada, Manabu Inoue, Takayuki Matsuki, Takuya Okata, Masaya Kumamoto, Naoki Tagawa, Akira Okamoto, Toshiyuki Miyata, Masafumi Ihara, Masatoshi Koga, Kazunori Toyoda
BACKGROUND: The crushed-tablet rivaroxaban concentration has been previously reported to be lower than the non-crushed concentration. However, the rivaroxaban concentration of fine granules has not yet been investigated. The anticoagulation intensity of rivaroxaban with fine granules, tablets, and crushed tablets was compared in acute stroke patients to assess the efficacy of each form. METHODS AND FINDINGS: Hospitalized patients over 75 years old with acute stroke who started taking rivaroxaban from April 2012 to September 2017 were included...
2019: PloS One
Fatima D Alves Pereira, Melissa L Hickson, Paddy A J Wilson
History A 65-year-old man presented to the emergency department with a 1-week history of constipation, which was associated with increasing abdominal distention and not passing flatus. Four weeks prior to the current admission he had been diagnosed with metastatic primary adenocarcinoma of the appendix. One week ago, he had been hospitalized with small-bowel obstruction, for which he required laparotomy and loop ileostomy. His medical history included basal cell carcinoma, rheumatoid arthritis, and Barrett esophagus...
April 2019: Radiology
Binbin Zhu, Jianhua Yan
BACKGROUND: Paragangliomas are groups of neuroendocrine neoplasms originating from neural crest cells throughout the body, but are rarely observed within the orbit. CASE REPORT: Two patients, a 4-year-old male and 27-year-old female, presented with a slow-growing proptosis. Well-defined masses were located in the superomedial (male) and temporal (female) portion of the right orbit and involved the entire bodies of either the superior (male) or lateral (female) rectus muscles...
March 15, 2019: Journal of Craniofacial Surgery
Shan Fan, Tao Guo, Baojiang Chen, Junqun Xiong, Shane Havens, Vikas Gulati, Carol B Toris
BACKGROUND: Glaucoma prevalence and subtype profile vary across different racial and ethnic groups. This study provides a comparative evaluation of differences in aqueous humour dynamics (AHD) and ocular biometrics in healthy Chinese and Caucasian adults of two different age groups. METHODS: Data from two independent studies with identical designs were compared. Cohorts included young adults (20-30 years old, 32 Chinese and 39 Caucasians) and older adults (>50 years old, 37 Chinese and 46 Caucasians)...
March 20, 2019: British Journal of Ophthalmology
Chun-Hung Chang, Shang-Wen Tsai, Kuei-Hsiang Hsu, Ming-Chau Chang, Wei-Ming Chen, Yu-Ping Su
BACKGROUND: We compared the clinical efficacy of normal C-reactive protein (CRP) expression (< 1.0 mg/dL), with a two-week drug holiday test (DHT) and without (DHT) as a reimplantation criterion, based on subsequent infections after a two-stage revision of a total knee arthroplasty of a periprosthetic joint infection (PJI). METHODS: A 10-year review of 58 patients (mean age: 73.3 years old; mean follow-up: 46.2 months), there were 31 patients in the DHT group and 27 patients in the DHT group...
March 11, 2019: Journal of the Chinese Medical Association: JCMA
Ching Wei Lee, Shih Hsien Sung, Wei Ming Huang, Yi Lin Tsai, Hsiang Yao Chen, Chiao Po Hsu, Chun Che Shih, Kuo Piao Chung
BACKGROUND AND OBJECTIVES: Age is a traditional risk factor for open-heart surgery. The efficacy and safety of transcatheter edge-to-edge mitral valve repair, using MitraClip (Abbott Vascular), has been demonstrated in patients with severe mitral regurgitation (MR). Since octogenarians or older patients are usually deferred to receive open-heart surgery, the main interest of this study is to elucidate the procedural safety and long-term clinical impact of MitraClip in elderly patients...
February 20, 2019: Korean Circulation Journal
Jessica Parrott, Alexander Shilling, Heather J Male, Marium Holland, Cecily A Clark-Ganheart
Background: Hemophagocytic lymphohistiocytosis (HLH) is a rare disease that can be fatal in pregnancy. We report two cases of severe HLH that highlight etoposide use in pregnancy. Case 1: 28-year-old G2P1 with lupus presented at 18 weeks with acute hypoxic respiratory failure, hepatic dysfunction, leukopenia, thrombocytopenia, and elevated ferritin. Bone marrow biopsy confirmed HLH. Etoposide and corticosteroid treatment was initiated per HLH protocol; however clinical status declined rapidly...
2019: Case Reports in Obstetrics and Gynecology
Miyuki Miyamoto, Nobuyuki Ishii, Hitoshi Mochizuki, Kazutaka Shiomi, Tomoko Kaida, Hideki Chuman, Masamitsu Nakazato
We describe our encounter with a 39-year-old man who exhibited acute painless visual loss and progressive gait disturbance. He had tendinous xanthoma and several neuroophthalmological findings indicative of optic neuropathy in the right eye, including afferent pupillary defect, cecocentral scotoma, and optic disc swelling. Neurological examination showed cerebellar ataxia and pyramidal weakness. Brain magnetic resonance imaging revealed bilateral swelling in the optic nerves with gadolinium-enhancement suggesting optic neuritis, an enlarged fourth ventricle, atrophy of the cerebellum, and hyperintensities in the bilateral dentate nuclei...
2019: Case Reports in Neurological Medicine
Su Fen Ang, Clara Si Hua Tan, Jessie Choi Wan Fong, Su Chi Lim
A 22-year-old man was referred for continuation of diabetes mellitus treatment. He was first diagnosed with diabetes mellitus 2 months after birth, when he failed to thrive and showed symptoms of diabetic ketoacidosis. There was no family history of diabetes mellitus. The patient did not exhibit the full set of features to be qualified for any developmental delay, epilepsy and neonatal diabetes mellitus (DEND) syndrome. Insulin replacement therapy was initiated; however, management was challenged by wide glycemic excursion, hypoglycemic unawareness and insulin-associated cutaneous lipo-hypertrophy...
March 19, 2019: European Journal of Human Genetics: EJHG
Olena Ivanova, Masna Rai, Wendo Mlahagwa, Jackline Tumuhairwe, Abhishek Bakuli, Viola N Nyakato, Elizabeth Kemigisha
BACKGROUND: Humanitarian crises and migration make girls and women more vulnerable to poor sexual and reproductive health (SRH) outcomes. Nevertheless, there is still a dearth of information on SRH outcomes and access to SRH services among refugee girls and young women in Africa. We conducted a mixed-methods study to assess SRH experiences, knowledge and access to services of refugee girls in the Nakivale settlement, Uganda. METHODS: A cross-sectional survey among 260 adolescent girls 13-19 years old was conducted between March and May 2018...
March 19, 2019: Reproductive Health
Getaneh Alemu, Ashenafi Abossie, Zerihun Yohannes
BACKGROUND: Intestinal parasites still pose major public health problems in developing countries like Ethiopia. Local epidemiological data is indispensable in order to design and monitor prevention and control strategies. Therefore the present study aimed to assess the prevalence of intestinal parasitic infections and associated factors among students at Birbir town, Southern Ethiopia. METHODS: A school-based cross-sectional study was conducted from March to May 2018...
March 19, 2019: BMC Infectious Diseases
Naihong Yan, Lirong Xiao, Chen Hou, Bo Guo, Wei Fan, Yingping Deng, Ke Ma
BACKGROUND: Congenital nystagmus (CN) and congenital cataracts are distinct eye diseases and are usually isolated. Cases with CN and congenital cataracts caused by different genes in one family have been rarely reported. CASE PRESENTATION: A 27-year-old man presented with CN and congenital cataracts and he underwent cataract extraction 2 weeks after birth. Three years later, he had posterior chamber intraocular lens implantation. The proband's mother was only afflicted by bilateral lens opacities...
March 19, 2019: BMC Medical Genetics
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