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JOURNAL ARTICLE
Yu-Qin Sun, Qing Zhong, Chen-Bin Lv, Ji-Yun Zhu, Guang-Tan Lin, Zhi-Quan Zhang, Dong Wu, Cai-Ming Weng, Qiu-Xian Chen, Ming-Qiao Lian, Wei-Ming Zeng, Yong-Bin Zhang, Qi-Yue Chen, Jian-Xian Lin, Jian-Wei Xie, Ping Li, Chao-Hui Zheng, Jun Lu, Li-Sheng Cai, Chang-Ming Huang
BACKGROUND: The safety and efficacy of neoadjuvant immunochemotherapy (nICT) for locally advanced gastric cancer (LAGC) remain controversial. METHODS: Patients with LAGC who received either nICT or neoadjuvant chemotherapy (nCT) at 3 tertiary referral teaching hospitals in China between January 2016 and October 2022 were analysed. After propensity-score matching (PSM), comparing the radiological response, pathological response rate, perioperative outcomes, and early recurrence between the two groups...
April 23, 2024: International Journal of Surgery
#2
JOURNAL ARTICLE
Junji Kawada, Minami Maruyama, Tomonori Nomura, Manatsu Mizuno, Akio Fukada, Shinya Kidogami, Yoshiki Taniguchi, Kei Asukai, Hideki Osawa, Yukako Mokutani, Tomoya Kishimoto, Hajime Hirose, Ho Min Kim, Shinichi Yoshioka, Yo Sasaki
BACKGROUND: Robotic gastrectomy(RG)for gastric cancer(GC)has been covered by health insurance since 2018. In this study, we examined the results of RG for GC at our hospital during the initial period of its introduction. MATERIALS AND METHOD: From August 2022 to May 2023, we retrospectively examined the surgical outcomes and short-term postoperative outcomes of the first 9 patients who underwent RG for GC at our hospital. RESULTS: The median patient age was 77(67-82) years, gender was 4 males and 5 females, and distal gastrectomy was performed in all patients...
April 2024: Gan to Kagaku Ryoho. Cancer & Chemotherapy
#3
JOURNAL ARTICLE
Tetsushi Nakagawa, Yuji Yamamoto, Senichiro Yanagawa, Shohei Shiozaki, Yuuki Kaneko, Atsuhiro Watanabe, Mai Nishina, Daisuke Takei, Yusuke Sumi, Minoru Yamaki, Manabu Kurayoshi, Junji Hashizume, Akihiko Oshita, Masahiro Nakahara, Toshio Noriyuki
A 67-year-old man visited our hospital for epigastric pain. Esophagogastroduodenoscopy(EGD)revealed type 2 gastric cancer from the cardia to the gastric angle, and histopathological examination revealed papillary adenocarcinoma(pap), HER2-positive. Contrast-enhanced CT showed wall thickening mainly in the posterior wall of the gastric body, enlarged lymph nodes that were lumped together with the main lesion, and 8 low-absorption areas with ring shaped contrast effects in both lobes of the liver. The patient was diagnosed as gastric cancer cT4aN(+)M1[HEP], clinical Stage ⅣB...
April 2024: Gan to Kagaku Ryoho. Cancer & Chemotherapy
#4
JOURNAL ARTICLE
(no author information available yet)
Far-advanced gastric cancer has always been a challenging problem in clinical treatment and a key direction for breakthrough research. Non-surgical treatments are primarily managed in patients with far-advanced gastric cancer. However, with the advancement of therapeutic methods in recent years, tumor foci can be significantly regressed after effective preoperative treatment, in prospect ofregaining the opportunity of radical gastrectomy. In the surgical field, laparoscopic surgery, as one of the routine methods for gastric cancer, has proven effective in the treatment of initially resectable gastric cancer...
April 23, 2024: Zhonghua Yi Xue za Zhi [Chinese medical journal]
#5
JOURNAL ARTICLE
Shunyu Zhang, Qiancheng Hu, Xinchuan Chen, Nan Zhou, Qiyue Huang, Sirui Tan, Minggang Su, Hongfeng Gou
INTRODUCTION: Accurate baseline clinical staging is critical to inform treatment decision-making for patients with gastric cancers. Peritoneal metastasis (PM) is the most common form of metastasis in gastric cancer and mainly diagnosed by diagnostic laparoscopy and peritoneal lavage evaluation. However, diagnostic laparoscopy is invasive and less cost-effective. It is urgent to develop a safe, fast and non-invasive functional imaging method to verify the peritoneal metastasis of gastric cancer...
April 19, 2024: BMJ Open
#6
JOURNAL ARTICLE
Paolo Morgagni, Maria Bencivenga, Fatima Carneiro, Stefano Cascinu, Sarah Derks, Maria Di Bartolomeo, Claire Donohoe, Clarisse Eveno, Suzanne Gisbertz, Peter Grimminger, Ines Gockel, Heike Grabsh, Paulo Kassab, Rupert Langer, Sara Lonardi, Marco Maltoni, Sheraz Markar, Markus Moehler, Daniele Marrelli, Maria Antonietta Mazzei, Davide Melisi, Carlo Milandri, Paul Stefan Moenig, Bianca Mostert, Gianni Mura, Wojciech Polkowski, John Reynolds, Luca Saragoni, Mark I Van Berge Henegouwen, Richard Van Hillegersberg, Michael Vieth, Giuseppe Verlato, Lorena Torroni, Bas Wijnhoven, Guido Alberto Massimo Tiberio, Han-Kwang Yang, Franco Roviello, Giovanni de Manzoni
BACKGROUND: Many gastric cancer patients in Western countries are diagnosed as metastatic with a median overall survival of less than twelve months using standard chemotherapy. Innovative treatments, like targeted therapy or immunotherapy, have recently proved to ameliorate prognosis, but a general agreement on managing oligometastatic disease has yet to be achieved. An international multi-disciplinary workshop was held in Bertinoro, Italy, in November 2022 to verify whether achieving a consensus on at least some topics was possible...
April 18, 2024: Gastric Cancer
#7
JOURNAL ARTICLE
Simon Kuesters, Johanna Sundheimer, Uwe A Wittel, Sophia Chikhladze, Stefan Fichtner-Feigl, Esther A Biesel
BACKGROUND: Pancreatoduodenectomies are complex surgical procedures with a considerable morbidity and mortality even in high-volume centers. However, postoperative morbidity and long-term oncological outcome are not only affected by the surgical procedure itself, but also by the underlying disease. The aim of our study is an analysis of pancreatoduodenectomies for patients with pancreatic ductal adenocarcinoma (PDAC) and ampullary carcinoma (CAMP) concerning postoperative complications and long-term outcome in a tertiary hospital in Germany...
April 17, 2024: Langenbeck's Archives of Surgery
#8
JOURNAL ARTICLE
Ling-Hua Wei, Hua-Long Zheng, Zhen Xue, Bin-Bin Xu, Hong-Hong Zheng, Li-Li Shen, Zhi-Wei Zheng, Jian-Wei Xie, Chao-Hui Zheng, Chang-Ming Huang, Qi-Yue Chen, Ping Li
BACKGROUND: The role of minimally invasive surgery using robotics versus laparoscopy in resectable gastric cancer patients with a high body mass index (BMI) remains controversial. METHODS: A total of 482 gastric adenocarcinoma patients with BMI ≥ 25 kg/m2 who underwent minimally invasive radical gastrectomy between August 2016 and December 2019 were retrospectively analyzed, including 109 cases in the robotic gastrectomy (RG) group and 321 cases in the laparoscopic gastrectomy (LG) group...
April 16, 2024: Surgical Endoscopy
#9
JOURNAL ARTICLE
T Jagric, G Hladnik, R Kolaric, I Arpad, M Horvat, S Potrc
BACKGROUND: We performed a propensity score matched study comparing patients' short- and long-term results after laparoscopic omentum-preserving gastrectomy and open surgery with omentectomy with UICC stages 0-IV. METHODS: Between 2015 and 2022, 311 patients with gastric cancer underwent surgery at the University Clinical Centre Maribor. Of these, 249 met the inclusion criteria and 198 were included in the study group after PSM. RESULTS: Patients in both groups were well-balanced in demographic and pathological characteristics after PSM...
April 15, 2024: Surgical Endoscopy
#10
JOURNAL ARTICLE
Xiaoying Pan, Manrong Bi, Hao Wang, Chenyang Ma, Xianli He
PURPOSE: Accurately locating and analysing surgical instruments in laparoscopic surgical videos can assist doctors in postoperative quality assessment. This can provide patients with more scientific and rational solutions for healing surgical complications. Therefore, we propose an end-to-end algorithm for the detection of surgical instruments. METHODS: Dual-Branched Head (DBH) and Overall Intersection over Union Loss (OIoU Loss) are introduced to solve the problem of inaccurate surgical instrument detection, both in terms of localization and classification...
April 13, 2024: International Journal of Computer Assisted Radiology and Surgery
#11
JOURNAL ARTICLE
Wataru Soneda, Eisuke Booka, Ryoma Haneda, Sanshiro Kawata, Tomohiro Murakami, Tomohiro Matsumoto, Yoshifumi Morita, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Hiroya Takeuchi
PURPOSE: To compare changes in liver enzyme levels on postoperative day 1 between patients with and without silicone disc (SD) use during liver retraction in laparoscopic gastrectomy for gastric cancer and laparoscopic gastric mobilization for esophageal cancer. METHODS: This prospective randomized controlled phase II trial was conducted between June 30, 2020, and November 30, 2022, to investigate the benefits of using an SD with a Nathanson liver retractor (NLR) compared with those using an NLR in laparoscopic gastrectomy and gastric mobilization...
April 12, 2024: Surgery Today
#12
JOURNAL ARTICLE
Shoukun Chen, Yueyang Huang, Weizheng Mao
CONTEXT: Laparoscopic gastrectomy (LG) provides advantages such as rapid postoperative recovery and little trauma, but postoperative complications are still unavoidable. Detecting serious complications after LG surgery is still a difficult problem for digestive surgeons. OBJECTIVE: The study intended to evaluate the clinical significance of the C-reactive protein (CRP) ratio in predicting postoperative complications after LG. DESIGN: The research team performed a retrospective analysis...
April 12, 2024: Alternative Therapies in Health and Medicine
#13
JOURNAL ARTICLE
Xin Zhang, Ziran Wei, Hongbing Fu, Zunqi Hu, Weijun Wang, Ronglin Yan
BACKGROUND: Iatrogenic splenic injury (ISI) is a recognized complication in radical gastrectomy that may result in incidental splenectomy (IS). However, the predictors of such events remain largely unknown. METHODS: Medical records of the patients who underwent radical gastrectomy at our institution between January 2015 and December 2022 were retrospectively reviewed. Potential predictors of ISI and IS were collected and analyzed by multivariate logistic regression...
2024: Frontiers in Oncology
#14
Motoki Ebihara, Kentoku Fujisawa, Shusuke Haruta, Hironori Uruga, Masaki Ueno
The safety of laparoscopic surgery for advanced gastric and pancreatic cancers has been established individually, but there is little evidence for synchronous cancers. In this case, a 59-year-old man with a history of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) treatment for diffuse large B-cell lymphoma underwent laparoscopic surgery for a suspected pancreatic invasion of advanced gastric cancer. Pathology revealed double cancer of the stomach and pancreas. Laparoscopic total gastrectomy and distal pancreatectomy were successfully performed...
March 2024: Curēus
#15
JOURNAL ARTICLE
Qing Zhong, Dong Wu, Yiming Jiang, Qing-Liang He, Xue-Yi Dang, Dong-Bo Xu, Yuqin Sun, Guo-Qiang Su, Kai-Qing Guo, Li-Sheng Cai, Haoxiang Zhang, Wen Ye, Guangtan Lin, Ping Li, Jian-Wei Xie, Qi-Yue Chen, Chao-Hui Zheng, Jun Lu, Chang-Ming Huang, Jian-Xian Lin
BACKGROUND: The efficacy of laparoscopic completion total gastrectomy (LCTG) for remnant gastric cancer (RGC) remains controversial. METHODS: The primary outcome was postoperative morbidity within 30 days after surgery. Secondary outcomes included 3-year disease-free survival (DFS), 3-year overall survival (OS), and recurrence. Inverse probability treatment weighted (IPTW) was used to balance the baseline between LCTG and OCTG. RESULTS: Final analysis included 46 patients with RGC who underwent LCTG at the FJMUUH between June 2016 and June 2020...
April 9, 2024: International Journal of Surgery
#16
JOURNAL ARTICLE
Jiajie Zhou, Ruiqi Li, Shuai Zhao, Longhe Sun, Jie Wang, Yayan Fu, Daorong Wang
Early gastric cancer (EGC) refers to malignant tumor lesions that are limited to the mucosa and submucosa layers, regardless of the presence of lymph node metastasis. Typically, EGC has a low rate of perigastric lymph node metastasis, and long-term survival outcomes are good after radical surgical treatment. The primary objective of surgical treatment for EGC is to achieve functional preservation while ensuring a radical cure. Sentinel node navigation surgery (SNNS) is a surgical technique used in the treatment of EGC...
April 8, 2024: American Journal of Clinical Oncology
#17
JOURNAL ARTICLE
Zhenyu Chen, Guangyu Chen, Yan Li, Sha Kou, Tao Wang, Lin Zhang, Yongkuan Cao, Liye Liu
PURPOSE: Neoadjuvant chemotherapy is strongly recommended for advanced gastric cancer due to good local control and a high rate of R0 dissection with this strategy. Minimally invasive techniques such as laparoscopy-assisted or total laparoscopic approaches is becoming more and more acceptable in the treatment for gastric cancer. However, the safety and efficiency of total laparoscopic D2 gastrectomy (TLG) for advanced gastric cancer after neoadjuvant chemotherapy have not been well evaluated...
April 2024: Annals of Surgical Treatment and Research
#18
JOURNAL ARTICLE
Hao Guo, WeiFeng Sun, HaiTao Duan, Chi Zhang, MaoHua Wei, Pin Liang, Xiang Hu, Liang Cao
BACKGROUND: To investigate the short-term and long-term outcomes of preserving the celiac branch of the vagus nerve during laparoscopic distal gastrectomy. METHODS: A total of 149 patients with prospective diagnosis of gastric cancer who underwent laparoscopic-assisted distal gastrectomy (LADG) combined with Billroth-II anastomosis and D2 lymph node dissection between 2017 and 2018 were retrospectively analyzed. The patients were divided into the preserved LADG group (P-LADG, n = 56) and the resected LADG group (R-LADG, n = 93) according to whether the vagus nerve celiac branch was preserved...
April 6, 2024: World Journal of Surgical Oncology
#19
JOURNAL ARTICLE
Shutaro Sumiyoshi, Takeshi Kubota, Takuma Ohashi, Keiji Nishibeppu, Jun Kiuchi, Hiroki Shimizu, Tomohiro Arita, Yusuke Yamamoto, Hirotaka Konishi, Ryo Morimura, Yoshiaki Kuriu, Atsushi Shiozaki, Hisashi Ikoma, Hitoshi Fujiwara, Eigo Otsuji
Postoperative hepatobiliary enzyme abnormalities often present as postoperative liver dysfunction in patients with gastric cancer (GC). This study aimed to identify the risk factors for postoperative liver dysfunction and their clinical impact after GC surgery. We retrospectively analyzed the data of 124 patients with GC who underwent laparoscopic or robotic surgery at Kyoto Prefectural University of Medicine between 2017 and 2019. Twenty (16.1%) patients with GC developed postoperative liver dysfunction (Common Terminology Criteria for Adverse Events (CTCAE) version 5...
April 6, 2024: Scientific Reports
#20
JOURNAL ARTICLE
Zhen Tian, Mingyu Xia, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Qiannan Sun, Daorong Wang
BACKGROUND: The appropriateness of laparoscopic gastrectomy (LG) for super-geriatric patients with locally advanced gastric cancer (LAGC) is inconclusive, and the prognostic factors are also yet to be elucidated. Herein, we aimed to investigate the surgical and oncological outcomes of LG versus open gastrectomy (OG) for geriatric patients with LAGC who have outlived the average lifespan of the Chinese population (≥ 78 years). METHODS: This is a monocentric, retrospective, comparative study...
April 4, 2024: Surgical Endoscopy
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