Patrik Greguletz, Maria Plötz, Carolin Baade-Büttner, Christian G Bien, Katharina Eisenhut, Christian Geis, Robert Handreka, Jaqueline Klausewitz, Peter Körtvelyessy, Stjepana Kovac, Andrea Kraft, Jan Lewerenz, Michael Malter, Michael Nagel, Felix von Podewils, Harald Prüß, Anna Rada, Johanna Rau, Sebastian Rauer, Rosa Rößling, Thomas Seifert-Held, Kai Siebenbrodt, Kurt-Wolfram Sühs, Simone C Tauber, Franziska Thaler, Judith Wagner, Jonathan Wickel, Frank Leypoldt, Heike L Rittner, Claudia Sommer, Carmen Villmann, Kathrin Doppler
Autoantibodies against contactin-associated protein 2 (Caspr2) not only induce limbic autoimmune encephalitis but are also associated with pain conditions. Here, we analyzed clinical data on pain in a large cohort of patients included into the German Network for Research in Autoimmune Encephalitis. Out of 102 patients in our cohort, pain was a frequent symptom (36% of all patients), often severe (63.6% of the patients with pain) and/or even the major symptom (55.6% of the patients with pain). Pain phenotypes differed between patients...
February 22, 2024: Journal of Neurology