Christian Mueller, Kenneth McDonald, Rudolf A de Boer, Alan Maisel, John G F Cleland, Nikola Kozhuharov, Andrew J S Coats, Marco Metra, Alexandre Mebazaa, Frank Ruschitzka, Mitja Lainscak, Gerasimos Filippatos, Petar M Seferovic, Wouter C Meijers, Antoni Bayes-Genis, Thomas Mueller, Mark Richards, James L Januzzi
Natriuretic peptide [NP; B-type NP (BNP), N-terminal proBNP (NT-proBNP), and midregional proANP (MR-proANP)] concentrations are quantitative plasma biomarkers for the presence and severity of haemodynamic cardiac stress and heart failure (HF). End-diastolic wall stress, intracardiac filling pressures, and intracardiac volumes seem to be the dominant triggers. This paper details the most important indications for NPs and highlights 11 key principles underlying their clinical use shown below. NPs should always be used in conjunction with all other clinical information...
June 2019: European Journal of Heart Failure