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Ronaldo Sousa, Joana Garrido Nogueira, André Ferreira, Francisco Carvalho, Manuel Lopes-Lima, Simone Varandas, Amílcar Teixeira
The freshwater pearl mussel Margaritifera margaritifera is a highly threatened species in Europe. Several mechanisms may be responsible for the decline in distribution and abundance of European pearl mussel populations, but almost no quantitative data exists about the possible negative impacts of invasive alien species (IAS). In this study, we clearly demonstrate that the invasive signal crayfish Pacifastacus leniusculus predates pearl mussels, using a laboratorial experiment followed by in situ validation in four rivers in the North of Portugal (Mente, Rabaçal, Tuela and Baceiro Rivers; Douro Basin)...
February 7, 2019: Science of the Total Environment
Filipa Teixeira, Ana Cláudia Fonseca, Filomena Pinto
Acquired myelinated retinal nerve fibers (MRNF) is rare. The reported cases occur after optic disk injuries. We describe a case of a patient with neurofibromatosis type 1 and bilateral optic pathway glioma, who after 3 years' follow-up developed unilateral MRNF. Optical coherence tomography of the optic nerve disclosed progressive increased thickness and hyper-reflectivity of the peripapillary retinal nerve fiber layer associated with the myelinization process. Although the patient remains asymptomatic, myelinization continues to progress...
February 14, 2019: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Ana L E Santos, Gerlânia O Leite, Romulo F Carneiro, Renato R Roma, Valdenice F Santos, Maria H C Santos, Raquel O Pereira, Rafael C Silva, Celso S Nagano, Alexandre H Sampaio, Bruno A M Rocha, Plinio Delatorre, Adriana R Campos, Claudener S Teixeira
A new mannose/N-acetyl-dglucosamine-specific lectin, named MaL, was purified from seeds of Machaerium acutifolium by precipitation with ammonium sulfate, followed by affinity and ion-exchange chromatography. MaL haemagglutinates either native rabbit erythrocytes or those treated with proteolytic enzymes. MaL is highly stable by the ability to maintain its haemagglutinating activity after exposure to temperatures up to 50 °C. The lectin haemagglutinating activity was optimum between pH 6.0 and 7.0 and inhibited after incubation with d-mannose and N-acetyl-d-glucosamine and α-methyl-d-mannopyranoside...
February 14, 2019: Archives of Biochemistry and Biophysics
Michelle A Sugimoto, Juliana P Vago, Mauro Perretti, Mauro M Teixeira
The termination of inflammation is governed by endogenous molecules collectively referred to as 'mediators of resolution' of inflammation. There is now strong evidence to suggest that failed resolution may underpin autoimmune and inflammatory diseases and could thus be targeted to decrease inflammation. There are many molecules that have been described as mediators of resolution, and new players are still being continuously discovered. To support the emerging field of 'resolution pharmacology', here we discuss the scientific strategies required to qualify a molecule as a resolution mediator...
February 13, 2019: Trends in Immunology
Luiz Gustavo de Quadros, Marco Silva, Manoel Dos Passos Galvão Neto, Eduardo Grecco, Thiago Ferreira de Souza, André Teixeira, Guilherme Macedo, Roberto Luiz Kaiser Junior
No abstract text is available yet for this article.
February 13, 2019: Gastroenterología y Hepatología
Alexandre Mendonça Teixeira, Lara de Oliveira Arinelli, José Luiz de Medeiros, Ofélia de Queiroz F Araújo
Offshore oil/gas productions are power intensive and CO2 emitters from gas-fired power generation. This work investigates supersonic separator as a strategy for affording post-combustion capture backed up by cost reductions. Conventional offshore gas processing usually loses thermodynamic hydrate inhibitor methanol in processing and exported gas. This work analyses a supersonic separator variant gas processing simultaneously reducing methanol losses. Such process dramatically improves gas-plant profitability via cost-reduction of methanol make-up and power-consumption, simultaneously increasing revenues from liquefied-petroleum-gas by-product...
February 13, 2019: Journal of Environmental Management
Li Ge, Rena C Moon, Ha Nguyen, Luiz Gustavo de Quadros, Andre F Teixeira, Muhammad A Jawad
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is the preferred surgical intervention to treat morbid obesity. Despite the rising popularity of LSG, little is known on the histopathologic findings of the resected partial stomach specimens. Our study aims to identify prevalent pathologic findings of the removed stomach and explore the association between patient characteristics and abnormal findings. METHODS: A retrospective analysis was conducted using a prospectively maintained database of 649 patients who underwent LSG between November 1, 2013 and December 31, 2015 at our institution...
February 15, 2019: Surgical Endoscopy
Ivan Bergier, Ana Paula Souza Silva, Urbano Gomes Pinto de Abreu, Luiz Orcírio Fialho de Oliveira, Michely Tomazi, Fernando Rodrigues Teixeira Dias, Cátia Urbanetz, Ériklis Nogueira, Juliana Corrêa Borges-Silva
No abstract text is available yet for this article.
February 12, 2019: Science of the Total Environment
Naser Ali, Joao A Teixeira, Abdulmajid Addali, Maryam Saeed, Feras Al-Zubi, Ahmad Sedaghat, Husain Bahzad
This study demonstrates an electron beam physical vapour deposition approach as an alternative stainless steel thin films fabrication method with controlled layer thickness and uniform particles distribution capability. The films were fabricated at a range of starting electron beam power percentages of 3⁻10%, and thickness of 50⁻150 nm. Surface topography and wettability analysis of the samples were investigated to observe the changes in surface microstructure and the contact angle behaviour of 20 °C to 60 °C deionised waters, of pH 4, pH 7, and pH 9, with the as-prepared surfaces...
February 14, 2019: Materials
Caio Jordão Teixeira, Junia Carolina Santos-Silva, Dailson Nogueira de Souza, Alex Rafacho, Gabriel Forato Anhe, Silvana Bordin
Pancreatic islets from pregnant rats develop a transitory increase in the pancreatic β-cell proliferation rate and mass. Increased apoptosis during early lactation contributes to the rapid reversal of those morphological changes. Exposure to synthetic glucocorticoids during pregnancy has been previously reported to impair insulin secretion, but its impacts on pancreatic islet morphological changes during pregnancy and lactation have not been described. To address this issue, we assessed the morphological and molecular characteristics of pancreatic islets from rats that underwent undisturbed pregnancy (CTL) or were treated with dexamethasone between the 14th and 19th days of pregnancy (DEX)...
February 1, 2019: Endocrine Connections
Otávio Hallal Ferreira Raro, Daiana de Lima-Morales, Afonso Luis Barth, Tiago Galvão Paim, Mariana Preussler Mott, Cezar Vinícius Würdig Riche, Uirá Fernandes Teixeira, Fábio Luiz Waechter, Cícero Armídio Gomes Dias
No abstract text is available yet for this article.
February 15, 2019: Infection Control and Hospital Epidemiology
Heitor O Santos, Filipe J Teixeira
Hypogonadism affects an extensive part of the male population, especially among the elderly. The quest for treatment regarding low levels of serum testosterone and male infertility has, therefore, worldwide relevance. Zinc has important biological actions insofar as the male reproductive physiology and endocrine system. In general, a common and safe recommendation for zinc in the treatment of male hypogonadism is 220 mg of zinc sulfate (equivalent to 50 mg of elemental zinc) twice a day, over one to four months...
February 15, 2019: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
Eric H Au, Jeremy R Chapman, Jonathan C Craig, Wai H Lim, Armando Teixeira-Pinto, Shahid Ullah, Stephen McDonald, Germaine Wong
Background Patients with ESRD have a substantially increased cancer risk, but few studies have examined the patterns of cancer mortality along a patient's journey from dialysis to transplantation. METHODS: We identified all Australian patients on dialysis and patients with transplants from 1980 to 2014 from the Australia and New Zealand Dialysis and Transplant Registry. Using standardized mortality ratios (SMRs), we compared cancer mortality among patients on dialysis and patients with transplants versus the general population (overall and by age, sex, year, and site); we also performed a subgroup analysis excluding patients with preexisting cancers...
February 14, 2019: Journal of the American Society of Nephrology: JASN
Aline Silva de Miranda, Rodrigo Novaes Ferreira, Érica Leandro Marciano Vieira, Larissa Katharina Sabino Abreu, Fátima Brant, Luciene Bruno Vieira, Fabíola Mara Ribeiro, Fabiana Simão Machado, Milene Alvarenga Rachid, Antônio Lúcio Teixeira
Several studies have proposed cerebral malaria (CM) as a CD4+ and CD8+ T lymphocyte-mediated disease. However, there are no data regarding the recruitment and/or persistence of these cells in the CNS following the phase of infection resolution. Glutamate-mediate excitotoxicity has also been implicated in CM. Blockade of glutamate NMDA receptors by its noncompetitive antagonist MK801 modulates cytokine and neurotrophic factors expression preventing cognitive and depressive-like behavior in experimental CM. Herein, we aim to investigate the role of T lymphocytes in later outcomes in CM, and whether the protective role of MK801 is associated with T lymphocytes response...
February 7, 2019: Journal of Neuroimmunology
Patrick M McLaurin, Ryan Merritt, Juan C Dominguez, Erico S Teixeira, Jorge A Morales
We present a computational procedure that introduces low degrees of symmetry breaking into a restricted Hartree-Fock (RHF) state in order to induce higher symmetry breaking during the state's subsequent dynamics. The symmetries herein considered are those of electronic HF states as classified by Fukutome; those symmetries affect bond dissociations and internal rotations among other phenomena. Therefore, this investigation extends a part of Fukutome's time-independent analysis of symmetry breaking to the time-dependent (dynamical) regime...
February 14, 2019: Physical Chemistry Chemical Physics: PCCP
Scheilla Teixeira Strumillo, Marli Ferreira Curcio, Fábio Ferreira de Carvalho, MariaCecília Araripe Sucupira, Ricardo Sobhie Diaz, Hugo Pequeno Monteiro, Luiz Mário Ramos Janini
Although interleukin-24 (IL-24) has been extensively explored in the immunopathologies of autoimmune diseases, neoplasms, and infections, its role in HIV-1 infection has not been thoroughly elucidated to date. Therefore, the objective of this study was to evaluate the gene and protein expressions of IL-24 at the initial moments of HIV infection in PBMCs. Due to the pro-apoptotic role of IL-24, we evaluated the protein expression of caspase-3, as well as Annexin V/ Propidium Iodide flow cytometry and phosphorylation of ERK, which may induce an apoptotic signal block when phosphorylated...
February 13, 2019: Cell Biology International
Rhayanna B Gaglianone, Anderson Teixeira Santos, Flavia Fonseca Bloise, Tania Maria Ortiga-Carvalho, Manoel Luis Costa, Thereza Quirico-Santos, Wagner Seixas da Silva, Claudia Mermelstein
Mitochondria play an important role in providing ATP for muscle contraction. Muscle physiology is compromised in Duchenne muscular dystrophy (DMD) and several studies have shown the involvement of bioenergetics. In this work we investigated the mitochondrial physiology in fibers from fast-twitch muscle (EDL) and slow-twitch muscle (soleus) in the mdx mouse model for DMD and in control C57BL/10J mice. In our study, multiple mitochondrial respiratory parameters were investigated in permeabilized muscle fibers from 12-week-old animals, a critical age where muscle regeneration is observed in the mdx mouse...
February 13, 2019: Scientific Reports
Flávia Campos Lucena, Eura Martins Lage, Patrícia Gonçalves Teixeira, Alexandre Simões Barbosa, Rejane Diniz, Bashir Lwaleed, André Talvani, Patrícia Nessralla Alpoim, Luiza Oliveira Perucci, Luci Maria SantAna Dusse
OBJECTIVE: Investigating D-Dimer/D-Di and plasminogen activator inhibitor type-1/PAI-1 levels throughout gestation in women with preeclampsia/PE risk factors. METHODS: D-Di and PAI-1 plasma levels were determined in 28 women at 12-19, 20-29, 30-34 and 35-40 weeks of gestation. RESULTS: D-Di was lower at 12-19 weeks and higher at 30-34 weeks in women who developed PE versus who did not develop it. D-Di increased throughout gestation in both groups, peaking earlier in pregnant women who developed PE versus who did not develop it...
February 13, 2019: Hypertension in Pregnancy
Marcus Zulian Teixeira
INTRODUCTION:  In addition to the four pillars of homeopathy, vitalism and the miasmatic theory are often used to explain the health-disease process. According to Hahnemann's concepts, homeopathic miasms are the main obstacle to the cure of chronic diseases, with psora being the fundamental cause of all forms of diseases. According to modern genetics, the disease-promoting epigenetic alterations are the fundamental cause of the manifestation of chronic diseases. OBJECTIVE:  This article develops a philosophical-scientific correlation between chronic miasms and disease-promoting epigenetic modifications, aiming to justify the isopathic use of auto-sarcode of an individual's DNA as homeopathic medicine...
February 13, 2019: Homeopathy: the Journal of the Faculty of Homeopathy
Uirá Fernandes Teixeira, Marcos Bertozzi Goldoni, Fábio Luiz Waechter, José Artur Sampaio, Florentino Fernandes Mendes, Paulo Roberto Ott Fontes
BACKGROUND: After the publication of the first recommendations of ERAS Society regarding colonic surgery, the proposal of surgical stress reduction, maintenance of physiological functions and optimized recovery was expanded to other surgical specialties, with minimal variations. AIM: To analyze the implementation of ERAS protocols for liver surgery in a tertiary center. METHODS: Fifty patients that underwent elective hepatic surgery were retrospectively evaluated, using medical records data, from June 2014 to August 2016...
February 7, 2019: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
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