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https://read.qxmd.com/read/30784615/therapeutic-opportunities-for-hepcidin-in-acute-care-medicine
#1
REVIEW
Lakhmir S Chawla, Blaire Beers-Mulroy, George F Tidmarsh
Iron homeostasis is often disrupted in acute disease with an increase in catalytic free iron leading to the formation of reactive oxygen species and subsequent tissue-specific oxidative damage. This article highlights the potential therapeutic benefit of exogenous hepcidin to prevent and treat iron-induced injury, specifically in the management of infection from enteric gram-negative bacilli or fungi, malaria, sepsis, acute kidney injury, trauma, transfusion, cardiopulmonary bypass surgery, and liver disease...
April 2019: Critical Care Clinics
https://read.qxmd.com/read/30783723/trauma-on-a-recently-augmented-breast-as-a-trigger-for-mondor-s-disease
#2
Yordan P Yordanov
Mondor's disease is the eponym used to describe a self-limited phlebitis or thrombophlebitis of the superficial veins localized mainly on the thoracoabdominal area of the human body. Its clinical manifestation includes painful superficial cords causing skin retraction. This medical condition could be idiopathic, iatrogenic or a manifestation of underlying pathology such as breast cancer and seems to be more common than has been previously thought. The vast majority of the clinical studies and case reports to date focus on Mondor's disease as a disorder which is more or less directly related to a previous surgical intervention...
February 19, 2019: Aesthetic Plastic Surgery
https://read.qxmd.com/read/30783353/autostabilization-of-neglected-high-grade-fracture-dislocation-in-the-cervical-spine
#3
Kunal Shah, Akshay Gadiya, Abhay Nene
Neglected cervical spine trauma is rare with very few case series reported in literature. There are no clear guidelines for its treatment. If operative treatment is sought, the role of skull traction, type of approach (anterior only, posterior only, or combined), sequence of surgery, type of instrumentation, etc., have to be considered. Hence, the treatment is challenging. Autostabilization has been described in the natural history of degenerative lumbar spondylolisthesis. As a result, many patients are treated nonoperatively, obviating need of surgery...
October 2018: Journal of Craniovertebral Junction and Spine
https://read.qxmd.com/read/30783345/who-benefits-more-in-osteoporotic-fractures-pedicle-screw-instrumentation-or-kyphoplasty-for-american-society-of-anesthesiologists-ii-iii-patients
#4
Tjark Tassemeier, Marcel Haversath, Moritz Schutzbach, Marcus Jäger
Purpose: Osteoporotc fractures with posterior wall injury are commonly treated with a pedicle srcrew instrumentation (PSI) or a ballonkyphoplasty (BKP). A predictor for complications for these patients is the American Society of Anesthesiologists (ASA) class. Clinical results in ASA II/III patients who underwent BKP and PSI due to OF were evaluated to find the optimal treatment regimen. Materials and Methods: In a retrospective study design, ASA Class II and III patients with OF type OF 2 and OF 3 according to the German Society of Orthopedics and Trauma Surgery classification who underwent surgery between 2011 and 2016 were enrolled...
October 2018: Journal of Craniovertebral Junction and Spine
https://read.qxmd.com/read/30783075/nasogastric-tubes-can-cause-intramural-hematoma-of-the-esophagus
#5
Toru Yamada, Yasuaki Motomura, Eiji Hiraoka, Aki Miyagaki, Juichi Sato
BACKGROUND Intramural hematoma of the esophagus (IHE), a rare manifestation of acute mucosal injuries of the esophagus, can be caused by trauma such as endoscopic surgeries. Coagulation disorders increase the risk of IHE. The most common location of IHE is in the distal esophagus. The characteristic clinical triad of manifestations comprises acute retrosternal pain, odynophagia or dysphagia, and hematemesis. It is important to distinguish IHE from other acute conditions such as acute coronary syndrome, aortic dissection, and pulmonary embolism...
February 20, 2019: American Journal of Case Reports
https://read.qxmd.com/read/30782110/blunt-abdominal-trauma-in-a-european-trauma-setting-need-for-complex-or-non-complex-skills-in-emergency-laparotomy
#6
J Kosola, T Brinck, A Leppäniemi, L Handolin
BACKGROUND AND AIMS: Blunt abdominal trauma can lead to substantial organ injury and hemorrhage necessitating open abdominal surgery. Currently, the trend in surgeon training is shifting away from general surgery and the surgical treatment of blunt abdominal trauma patients is often done by sub-specialized surgeons. The aim of this study was to identify what emergency procedures are needed after blunt abdominal trauma and whether they can be performed with the skill set of a general surgeon...
February 20, 2019: Scandinavian Journal of Surgery: SJS
https://read.qxmd.com/read/30779725/distal-nail-target-and-alignment-of-distal-tibia-fractures
#7
Elyse Brinkmann, Frank DiSilvio, Michael Tripp, Mitchell Bernstein, Hobie Summers, William D Lack
OBJECTIVES: To assess the relationship between the distal nail target and postoperative alignment for distal tibia fractures treated with intramedullary nailing. DESIGN: Retrospective cohort study. SETTING: A single level 1 trauma center. PATIENTS/PARTICIPANTS: One hundred thirty distal tibia fractures treated with intramedullary nailing over a 10-year period. MAIN OUTCOME MEASUREMENTS: Malalignment >5 degrees...
March 2019: Journal of Orthopaedic Trauma
https://read.qxmd.com/read/30779619/simultaneous-fluoroscopic-guided-tibial-plateau-leveling-and-fracture-reduction-for-the-concurrent-treatment-of-chronic-cranial-cruciate-ligament-tear-and-comminuted-diaphyseal-fracture-of-the-tibia-and-fibula-in-a-dog
#8
Massimo Petazzoni, Michela Buiatti
CASE DESCRIPTION A 12-year-old obese spayed female American Staffordshire Terrier was admitted for evaluation of acute non-weight-bearing lameness of the right pelvic limb attributed to motor vehicle-related trauma that occurred 2 hours previously. The owners reported a chronic, progressive weight-bearing lameness of the right pelvic limb secondary to a complete cranial cruciate ligament (CrCL) rupture that was diagnosed 6 months previously. They had declined surgery for CrCL repair because of the advanced age of the dog...
March 1, 2019: Journal of the American Veterinary Medical Association
https://read.qxmd.com/read/30779490/-childhood-glaucoma
#9
REVIEW
Orna Geyer, Nurit Mathalone, Alvit Wolf, Alina Melamud
"Childhood glaucoma" is a heterogenic group of diseases, characterized by elevated intraocular pressure (IOP) associated with optic-disc damage and other ocular comorbidities. Diagnosis requires two or more of the following: elevated IOP, optic nerve damage, enlarged cornea or Descemet's membrane ruptures, enlarged eye, high myopia and visual field defects. Childhood glaucoma is classified as primary if it occurs as an isolated ocular disease, and secondary, when the disease occurs along with other ocular anomalies or systemic diseases such as Neurofibromatosis and Sturge-Weber, or with acquired conditions such as uveitis complications, ocular trauma, cataract surgery, as well as from systemic and ocular steroid use...
February 2019: Harefuah
https://read.qxmd.com/read/30779486/-ophthalmic-manifestations-of-silent-sinus-syndrome
#10
Arie Nemet, Peter Martin, Shay Ofir, Firas Kasem
AIMS: To describe 7 case reports of "silent sinus syndrome" (SSS) cases and review the literature on this topic. METHODS: A retrospective review of 7 consecutive cases of SSS seen by the authors from 2005 to 2017. Data collected included patient demographics, clinical presentation, imaging findings, surgery performed, outcome and follow up. RESULTS: Seven patients were identified presenting with SSS, two of them following trauma, and the rest with no relevant history...
February 2019: Harefuah
https://read.qxmd.com/read/30776945/experience-of-nail-bed-injuries-at-a-tertiary-hand-trauma-unit-a-12-month-review-and-cost-analysis
#11
Lara Yildirimer, Colin T Brewster, Hina Aziz, Zeynep Unluer, Barbara Jemec, Anna De Leo
The aim of this study was to analyse the management of nail bed injuries from a clinical and economic perspective. We carried out a retrospective analysis of nail bed injuries treated operatively at a tertiary Plastic Surgery Hand Trauma Unit during 2016. The National Schedule of Reference Costs (2015-2016) was used to estimate the costs of treating 630 patients. The most common mechanism was a crush injury in a door (33%). Fifty-five per cent of patients had an associated tuft fracture. The minimum cost per annum for patients treated for nail bed injuries in our unit was calculated to be £511,560 (€573,362; US$666,664)...
February 18, 2019: Journal of Hand Surgery, European Volume
https://read.qxmd.com/read/30776095/scuba-medicine-for-otolaryngologists-part-ii-diagnostic-treatment-and-dive-fitness-recommendations
#12
Jonathan R Mallen, Daniel S Roberts
OBJECTIVES: Challenge current practices and misconceptions in treating recreational SCUBA (Self-contained underwater breathing apparatus) divers. Differentiate patients who are fit to dive and those with relative and absolute contraindications. Redefine the standard of care for fitness to dive parameters based on the most up-to-date evidence. METHODS: We conducted a review of the available medical and diving literature in English, German, Spanish, Italian, Turkish, and French to determine the degree of evidence or lack thereof behind recommendations for treating SCUBA divers...
February 18, 2019: Laryngoscope
https://read.qxmd.com/read/30773823/inflammatory-biomarkers-vascular-procedures-of-lower-limbs-and-wound-healing
#13
Paolo Sapienza, Andrea Mingoli, Valeria Borrelli, Gioia Brachini, Daniele Biacchi, Antonio V Sterpetti, Raffaele Grande, Raffaele Serra, Elvira Tartaglia
Abnormal, persistent inflammation after bypass surgery could prevent healing of an ischaemic foot lesion. In 37 patients with peripheral arterial disease (PAD) (Rutherford Grade III Category 5) who underwent infrapopliteal vein graft and midfoot amputation, plasma levels of fibrinogen, C-reactive protein (CRP), interleukin-1 (IL-1), interleukin-6 (IL-6), tumour necrosis factor-α (TNF-α), and matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9) were determined preoperatively and during the follow up. Nine patients without clinical and Doppler evidence of arterial disease, who underwent post-traumatic midfoot primary amputation, were included in the experiment group, and 15 age-matched healthy volunteers served as control...
February 17, 2019: International Wound Journal
https://read.qxmd.com/read/30773470/national-trends-in-orthopaedic-surgery-resident-adult-case-logs
#14
Todd P Pierce, Daniel Ermann, Anthony J Scillia, Anthony Festa, Arash Emami, Vincent K McInerney
OBJECTIVE: Our purpose was to assess United States data to determine if there were changes in the number of adult cases that graduating orthopaedic surgery resident logged. DESIGN: We assessed the Accreditation Council for Graduate Medical Education data from 2010 to 2016 to identify the number of cases that were reported by graduating orthopaedic surgery residents through the United States. Specifically, we analyzed the mean total number of adult cases per graduating resident...
February 14, 2019: Journal of Surgical Education
https://read.qxmd.com/read/30773215/blobbing-injury-patterns
#15
Peter Kaiser, David Sailer, Anna Spicher, Rohit Arora, Michael Zegg
INTRODUCTION: "Blobbing" is a modern outdoor activity where a participant sits on the end of a partially inflated air bag ("blobber") and is launched into the water when another participant jumps onto the air bag from a platform on the opposite side ("jumper"). This is the first study to evaluate the injury patterns associated with blobbing. PATIENTS AND METHODS: A retrospective data analysis was conducted based on 86 patients who sustained blobbing injuries between January 2011 and December 2016...
February 8, 2019: Injury
https://read.qxmd.com/read/30772977/-surgical-results-and-sagittal-alignment-analysis-of-different-fusion-levels-for-degenerative-scoliosis
#16
X L Meng, Y Hai, G Xu, J C Yang, Q J Su
Objective: To retrospectively investigate the effects of long segment fusion and short segment fusion on lumbar sagittal alignment and quality of life in patients with degenerative scoliosis. Methods: From January 2011 to December 2014, 75 patients with degenerative scoliosis were treated with pedicle screw fixation. Total of 56 females and 19 males were included in this study. Fifty-four patients underwent short-segment fusion (≤3 segments) and 21 patients underwent long-segment fusion (>3 segments). The average age of the patients was (63±8) years...
January 29, 2019: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/30772878/-endovascular-repair-of-traumatic-injury-to-the-descending-aorta-and-the-right-subclavian-artery-report-of-a-case
#17
Yasuyuki Kobayashi, Koji Nakanishi, Mikizo Nakai
A 32-year-old man leaping down from the 3rd floor of his house got injured and was transferred to our center. Pseudoaneurysm at the aortic isthmus as well as pelvic and lower limb fractures were observed by computed tomography (CT) scan. Thoracic endovascular aortic repair(TEVAR)of the thoracic aorta was performed from zone 2, followed by external skeletal fixation. Postoperative chest X-ray revealed right hemothorax, and CT scan showed active bleeding from the right subclavian artery in addition to splenic artery pseudoaneurysm...
February 2019: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://read.qxmd.com/read/30772617/pediatric-preseptal-and-orbital-cellulitis-a-10-year-experience
#18
Joana Caldeira Santos, Sara Pinto, Sofia Ferreira, Catarina Maia, Sandra Alves, Vinhas da Silva
OBJECTIVE: Characterize clinical features, epidemiology and treatment of hospitalized pediatric cases of preseptal and orbital cellulitis. METHODS: Retrospective study of children/adolescents admitted to a central hospital with preseptal and orbital cellulitis between 2007 and 2017. RESULTS: A total of 122 cases were included, 80.3% with preseptal cellulitis and 19.7% with orbital cellulitis. Patients had a median age of 5 years. Sinusitis was the most common predisposing factor (40...
February 7, 2019: International Journal of Pediatric Otorhinolaryngology
https://read.qxmd.com/read/30771540/the-first-case-report-of-bilateral-spontaneous-otogenic-pneumocephalus
#19
Richard Voldřich, Martin Májovský, Martin Chovanec, David Netuka
BACKGROUND: Pneumocephalus is commonly associated with cranial trauma including surgical interventions. Spontaneous pneumocephalus on the other hand is a rare diagnosis. Reported cases were predominantly unilateral. We report unique case of a bilateral spontaneous pneumocephalus probably related to bilateral tegmen defect related to repeated Politzer maneuvers. CASE DESCRIPTION: A 78-year-old man suffered from vertigo, tinnitus, instability and mild expressive aphasia...
February 13, 2019: World Neurosurgery
https://read.qxmd.com/read/30770996/anterior-inferior-tibiofibular-ligament-avulsion-fractures-in-operatively-treated-ankle-fractures-a-retrospective-analysis
#20
Merel F N Birnie, Kaz L J van Schilt, Fay R K Sanders, Peter Kloen, Tim Schepers
BACKGROUND: There is no consensus about the optimal treatment of anterior inferior ligament avulsion fractures of the ankle. The aim of this study is to provide insights regarding the incidence of anterior inferior ligament avulsion fractures, the association with fracture type, and correlation with treatment. METHODS: This study is a retrospective analysis in a level-1 trauma center of adult patients with an ankle fracture operated between the dates 01-01-2009 and 01-09-2017 who had a pre- and postoperative CT-scan...
February 15, 2019: Archives of Orthopaedic and Trauma Surgery
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