Jong-Jheng Luo, Sheng-Wei Pan, Jia-Hui Yang, Tian-Lin Chang, Peng-Yi Lin, Chen-Liang Wu, Wei-Fang Liu, Xin-Ru Huang, Igor O Koshevoy, Pi-Tai Chou, Mei-Lin Ho
We report on a selective paper-based method and a microfluidic paper-based analytical device (μPAD) for the detection of human plasma glucose and tear glucose using carbopol polymer-encapsulated Au(I) complex (AuC₂C₆H₄OMe)₂(Ph₂P(C₆H₄)₃PPh₂), ( B5 ). To the best of our knowledge, this demonstrates for the first time the glucose sensing based on dual emission, i.e., fluorescence and phosphorescence, of a single type molecule on the carbopol polymer. Upon addition of human blood treated with anticoagulants to μPADs, plasma is separated from the blood and flows into the response region of the μPADs to react with carbopol polymer-encapsulated B5 , in which the ratiometric luminescence is analyzed...
September 7, 2018: Polymers