keyword
https://read.qxmd.com/read/38461457/revolutionizing-bone-tumor-management-cutting-edge-breakthroughs-in-limb-saving-treatments
#21
REVIEW
Vikramaditya Rai, Shahzad Waqas Munazzam, Noman Ullah Wazir, Irum Javaid
Limb salvage surgery has revolutionized the approach to bone tumors in orthopedic oncology, steering away from historical amputations toward preserving limb function and enhancing patient quality of life. This transformative shift underscores the delicate balance between tumor eradication and optimal postoperative function. Primary and metastatic bone tumors present challenges in early detection, differentiation between benign and malignant tumors, preservation of function, and the risk of local recurrence...
March 10, 2024: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/38461138/an-innovative-3d-hydroxyapatite-patient-specific-implant-for-maxillofacial-bone-reconstruction-a-case-series-of-13-patients
#22
JOURNAL ARTICLE
Simon Systermans, Elisabeth Cobraiville, Séverine Camby, Christophe Meyer, Aurélien Louvrier, Suen An Lie, Thomas Schouman, Sergio Siciliano, Olivier Beckers, Vinciane Poulet, Nicolas Ullmann, Grégory Nolens, Vincent Biscaccianti, Jean-Luc Nizet, Jean-Yves Hascoët, Yves Gilon, Luciano Vidal
The study aimed to evaluate and discuss the use of an innovative PSI made of porous hydroxyapatite, with interconnected porosity promoting osteointegration, called MyBone Custom® implant (MBCI), for maxillofacial bone reconstruction. A multicentric cohort of 13 patients underwent maxillofacial bone reconstruction surgery using MBCIs for various applications, from genioplasty to orbital floor reconstruction, including zygomatic and mandibular bone reconstruction, both for segmental defects and bone augmentation...
February 28, 2024: Journal of Cranio-maxillo-facial Surgery
https://read.qxmd.com/read/38459610/clinical-benefits-of-autologous-platelet-concentrate-in-periodontal-intrabony-defects-a-network-meta-analysis-of-randomized-controlled-trials
#23
REVIEW
Yue Cui, Yuhe Mai, Xuewei Liu, Hong Mu
This study aimed to compare clinical benefits of autologous platelet concentrate with other periodontal regenerative approaches in intrabony defects. An electronic and hand search of studies up to December 2022 was conducted. Randomized controlled trials with at least 6 months of follow-up were identified to compare autologous platelet concentrates with enamel matrix derivative, bone graft, guided tissue regeneration, and open-flap debridement. All approaches involved papilla preservation flap surgery. The outcomes included probing depth reduction, clinical attachment level gain, linear bone fill, and safety...
March 8, 2024: European Journal of Oral Sciences
https://read.qxmd.com/read/38459593/a-biodegradable-pva-coating-constructed-on-the-surface-of-the-implant-for-preventing-bacterial-colonization-and-biofilm-formation
#24
JOURNAL ARTICLE
Zhonghua Lei, Haifeng Liang, Wei Sun, Yan Chen, Zhi Huang, Bo Yu
BACKGROUND: Bone implant infections pose a critical challenge in orthopedic surgery, often leading to implant failure. The potential of implant coatings to deter infections by hindering biofilm formation is promising. However, a shortage of cost-effective, efficient, and clinically suitable coatings persists. Polyvinyl alcohol (PVA), a prevalent biomaterial, possesses inherent hydrophilicity, offering potential antibacterial properties. METHODS: This study investigates the PVA solution's capacity to shield implants from bacterial adhesion, suppress bacterial proliferation, and thwart biofilm development...
March 8, 2024: Journal of Orthopaedic Surgery and Research
https://read.qxmd.com/read/38458498/depletion-of-complement-factor-3-delays-the-neuroinflammatory-response-to-intracortical-microelectrodes
#25
JOURNAL ARTICLE
Sydney S Song, Lindsey N Druschel, Jacob H Conard, Jaime J Wang, Niveda M Kasthuri, E Ricky Chan, Jeffrey R Capadona
The neuroinflammatory response to intracortical microelectrodes (IMEs) used with brain-machine interfacing (BMI) applications is regarded as the primary contributor to poor chronic performance. Recent developments in high-plex gene expression technologies have allowed for an evolution in the investigation of individual proteins or genes to be able to identify specific pathways of upregulated genes that may contribute to the neuroinflammatory response. Several key pathways that are upregulated following IME implantation are involved with the complement system...
March 6, 2024: Brain, Behavior, and Immunity
https://read.qxmd.com/read/38456331/association-between-blood-markers-and-the-progression-of-osseointegration-in-percutaneous-prostheses-patients-a-pilot-study
#26
JOURNAL ARTICLE
Andrew Miller, Sujee Jeyapalina, Jayant P Agarwal, James Peter Beck
Patients implanted with osseointegrated (OI) prosthetic systems have reported vastly improved upper and lower extremity prosthetic function compared with their previous experience with socket-suspension systems. However, OI systems have been associated with superficial and deep-bone infections and implant loosening due, in part, to a failure of the osseointegration process. Although monitoring the osseointegration using circulating biomarkers has clinical relevance for understanding the progression of osseointegration with these devices, it has yet to be established...
March 2024: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://read.qxmd.com/read/38453351/gap-patterns-and-radiographic-follow-up-of-newer-generation-cementless-total-knee-arthroplasty-designs
#27
JOURNAL ARTICLE
Abigail Frazer, Jason B T Lim, Matthew G Teeter, James Howard, Edward M Vasarhelyi, Brent A Lanting
BACKGROUND: Interest in cementless total knee arthroplasty (TKA) has increased with advancement of biomaterials and implant design and associated improved longevity. We sought to evaluate the gap patterns and radiolucent zones radiographically for 2 newer-generation cementless TKA designs. METHODS: We retrospectively reviewed our single-institution database between January 2017 and December 2019. We identified patients with a porous keeled tibia base-plate with 4-bullet cruciform spikes and peri-apatite coated femoral component (study group 1) and patients who received a cementless porous coated femoral component and rotating platform tibia baseplate with 4 peripheral porous coated pegs around a central cone (study group 2)...
2024: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://read.qxmd.com/read/38450531/patches-in-congenital-diaphragmatic-hernia-a-systematic-review
#28
JOURNAL ARTICLE
Amulya K Saxena, Romilly K Hayward
OBJECTIVE: This systematic review aims to evaluate current choice in practice and outcomes of biomaterials used in patch repair of congenital diaphragmatic hernia (CDH). BACKGROUND: Multiple biomaterials, both novel and combinations of pre-existing materials are employed in patch repair of large size CDH. METHODS: Literature search was performed across Embase, Medline, Scopus, and Web of Science. Publications that explicitly reported patch repair, material used and recurrences following CDH repair were selected...
March 7, 2024: Annals of Surgery
https://read.qxmd.com/read/38444930/beyond-synthetics-promising-outcomes-with-the-invengenx%C3%A2-bovine-pericardial-patch-for-ventricular-septal-defect-repair-in-a-young-pediatric-population
#29
Vishal V Bhende, Tanishq S Sharma, Mathangi Krishnakumar, Anikode S Ramaswamy, Kanchan Bilgi, Sohilkhan R Pathan
Ventricular septal defects (VSDs) are a prevalent congenital heart anomaly demanding safe and lasting interventions. This paper explores the application of Invengenx® bovine pericardial patch (Tisgenx, Irvine, California), a promising biomaterial, in VSD repair. We present two case studies: a seven-month-old infant and a three-year-old child undergoing VSD closure using autologous and bovine pericardial patches, respectively. Both patients tolerated the procedures well, experiencing no intra-operative complications and demonstrating excellent postoperative recovery...
March 2024: Curēus
https://read.qxmd.com/read/38444474/melt-blending-of-poly-lactic-acid-with-biomedically-relevant-polyurethanes-to-improve-mechanical-performance
#30
JOURNAL ARTICLE
Stefan Oschatz, Selina Schultz, Nicklas Fiedler, Volkmar Senz, Klaus-Peter Schmitz, Niels Grabow, Daniela Koper
Minimally invasive surgery procedures are of utmost relevance in clinical practice. However, the associated mechanical stress on the material poses a challenge for new implant developments. In particular PLLA, one of the most widely used polymeric biomaterials, is limited in its application due to its high brittleness and low elasticity. In this context, blending is a conventional method of improving the performance of polymer materials. However, in implant applications and development, material selection is usually limited to the use of medical grade polymers...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38436158/ceramic-biomaterials-in-dentistry-chemical-structure-and-biosafety-a-review-and-a-bibliometric-visual-mapping-on-scopus-database
#31
JOURNAL ARTICLE
F Inchingolo, A D Inchingolo, I A Charitos, A P Cazzolla, M Colella, R Gagliano-Candela, D Hazballa, I R Bordea, S R Tari, A Scarano, F Lorusso, L Riccaldo, A Palermo, G Dipalma, G Malcangi, A M Inchingolo
OBJECTIVE: A biomaterial is any non-pharmaceutical substance or a mixture of synthetic or natural substances used independently or as part of a system for any amount of time with the aim of mending, supporting the growth, or replacing tissues, organs, or functions of the body. It is a non-renewable material that interacts with biological systems. The purpose of this study was to assess the advances in ceramic biomaterials and perform a bibliometric mapping of the literature on the subject...
February 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38430209/epithelial-cyst-following-subepithelial-connective-tissue-graft-a-case-report
#32
Julien de Paula, Luise A B da Silva, Mariane A S Wayar, Eduardo B Campagnoli, Fábio A Dos Santos
BACKGROUND: Various surgical approaches have been employed to manage gingival recession, including subepithelial connective tissue grafting, which has yielded favorable outcomes. METHODS AND RESULTS: We present the case of a 17-year-old patient who developed gingival recession on tooth #6 following an esthetic crown lengthening procedure. The recession was treated with a subepithelial connective tissue graft; however, this case details the occurrence of two epithelial cysts adjacent to the region subjected to the surgical procedure, 6 months after surgery...
March 2, 2024: Clinical Advances in Periodontics
https://read.qxmd.com/read/38429932/snail-extract-for-skin-a-review-of-uses-projections-and-limitations
#33
REVIEW
Nupur Singh, Angela N Brown, Michael H Gold
BACKGROUND: Snail mucin is becoming increasingly popular for its wide range of ingredients and potential benefits. Snail extract's widespread appearance in cosmetic formulations encourages an investigation into the medical and cosmetic benefits. AIMS: This study aims to explore current literature on the variety of snail mucin applications. Specifically, we present a review of the uses, global market estimates and projects, and limitations to snail mucin. METHODS: A literature search was conducted on PubMed reviewing snail mucin and their application in medical and dermatologic fields examining their uses...
March 1, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38428122/in-vivo-assessment-of-marine-vs-bovine-origin-collagen-based-composite-scaffolds-promoting-bone-regeneration-in-a-new-zealand-rabbit-model
#34
JOURNAL ARTICLE
Gabriela S Diogo, María Permuy, Catarina F Marques, Cármen G Sotelo, Ricardo I Pérez-Martín, Julia Serra, Pio González, Fernando Munõz, Rogério P Pirraco, Rui L Reis, Tiago H Silva
The ability of human tissues to self-repair is limited, which motivates the scientific community to explore new and better therapeutic approaches to tissue regeneration. The present manuscript provides a comparative study between a marine-based composite biomaterial, and another composed of well-established counterparts for bone tissue regeneration. Blue shark skin collagen was combined with bioapatite obtained from blue shark's teeth (mColl:BAp), while bovine collagen was combined with synthetic hydroxyapatite (bColl:Ap) to produce 3D composite scaffolds by freeze-drying...
February 26, 2024: Biomater Adv
https://read.qxmd.com/read/38428093/mild-magnetic-hyperthermia-activated-immuno-responses-for-primary-bladder-cancer-therapy
#35
JOURNAL ARTICLE
Fenggang Qi, Qunqun Bao, Ping Hu, Yuedong Guo, Yang Yan, Xudong Yao, Jianlin Shi
Surgical intervention followed by chemotherapy is the principal treatment strategy for bladder cancer, which is hindered by significant surgical risks, toxicity from chemotherapy, and high rates of recurrence after surgery. In this context, a novel approach using mild magnetic hyperthermia therapy (MHT) for bladder cancer treatment through the intra-bladder delivery of magnetic nanoparticles is presented for the first time. This method overcomes the limitations of low magnetic thermal efficiency, inadequate tumor targeting, and reduced therapeutic effectiveness associated with the traditional intravenous administration of magnetic nanoparticles...
February 21, 2024: Biomaterials
https://read.qxmd.com/read/38423069/comprehensive-functional-outcome-analysis-and-importance-of-bone-remodelling-on-personalized-cranioplasty-treatment-using-poly-methyl-methacrylate-bone-flaps
#36
JOURNAL ARTICLE
Sandeep Iratwar, Sulob Roy Chowdhury, Shweta Pisulkar, Soumitra Das, Akhilesh Agarwal, Ashutosh Bagde, Balaji Paikrao, Syed Quazi, Bikramjit Basu
Cranioplasty involves the surgical reconstruction of cranial defects arising as a result of various factors, including decompressive craniectomy, cranial malformations, and brain injury due to road traffic accidents. Most of the modern decompressive craniectomies (DC) warrant a future cranioplasty surgery within 6-36 months. The conventional process of capturing the defect impression and polymethyl methacrylate (PMMA) flap fabrication results in a misfit or misalignment at the site of implantation. Equally, the intra-operative graft preparation is arduous and can result in a longer surgical time, which may compromise the functional and aesthetic outcomes...
February 29, 2024: Journal of Biomaterials Applications
https://read.qxmd.com/read/38416002/variables-influencing-bone-formation-after-transcrestal-sinus-floor-elevation-radiographic-and-tomographic-evaluations
#37
JOURNAL ARTICLE
Giacomo Mainetti, Tomaso Mainetti, Franco Bengazi, Ermenegildo Federico De Rossi, Karol Alí Apaza Alccayhuaman, Daniele Botticelli
PURPOSE: To evaluate the influence of initial implant protrusion within the subantral space on hard tissue gain for implants placed simultaneously with transcrestal sinus floor elevation (TSFE) with a biomaterial. MATERIALS AND METHODS: A total of 50 implants were placed after TSFE in 44 patients using either a human demineralized bone matrix or a deproteinized bone mineral matrix. Intraoral radiographs were obtained before and immediately after surgery. CBCT scans were obtained at the last follow-up (mean: 6...
February 27, 2024: International Journal of Oral & Maxillofacial Implants
https://read.qxmd.com/read/38413368/application-of-multi-layer-porcine-small-intestinal-submucosa-for-the-reconstruction-of-deep-corneal-defects-in-cats
#38
JOURNAL ARTICLE
JingWen Luo, ZhenLei Zhou
OBJECTIVE: This study documented the application of porcine small intestinal submucosa (SIS) as a stand-alone scaffold for treating deep corneal defects in cats. METHODS: Medical records of 20 cats with deep stromal ulcers, perforations, or corneal sequestra that underwent surgical treatment with SIS grafts between 2021 and 2022 were retrospectively reviewed. Data on re-epithelialization time, corneal transparency score, and complications were collected to analyze the reconstruction of deep corneal defects after SIS biomaterial implantation...
February 27, 2024: Veterinary Ophthalmology
https://read.qxmd.com/read/38411533/challenges-in-nasal-cartilage-tissue-engineering-to-restore-the-shape-and-function-of-the-nose
#39
JOURNAL ARTICLE
Delphine Vertu-Ciolino, Fanny Brunard, Edwin-Joffrey Courtial, Marielle Pasdeloup, Christophe Marquette, Emeline Perrier-Groult, Frédéric Mallein-Gerin, Jean-Daniel Malcor
The repair of nasal septal cartilage is a key challenge in cosmetic and functional surgery of the nose, as it determines its shape and its respiratory function. Supporting the dorsum of the nose is essential for both the prevention of nasal obstruction and the restoration of the nose structure. Most surgical procedures to repair or modify the nasal septum focus on restoring the external aspect of the nose by placing a graft under the skin, without considering respiratory concerns. Tissue engineering offers a more satisfactory approach, in which both the structural and biological roles of the nose are restored...
February 27, 2024: Tissue Engineering. Part B, Reviews
https://read.qxmd.com/read/38408759/phosphatidylserine-accelerates-wound-healing-and-reduces-necrosis-in-the-rats-growth-factor-activation
#40
JOURNAL ARTICLE
Partow Mirzaee Saffari, Pooria Asili, Sadaf Eshraghi, Ahad Muhammadnejad, Ahmad Reza Dehpour, Ramin Goudarzi, Alireza Partoazar
To examine the effect of topical phosphatidylserine (PS) on wound healing factors and tissue necrosis in in vivo models. Topical PS was applied to evaluate aspects of the wound healing process and growth factors production of vascular endothelial growth factors (VEGF) as well a necrosis reduction in the skin flap of rat models. Moreover, phenytoin (PHT) and cyclosporine A (CsA) were used topically as positive control treatments in wound and necrosis models, respectively. Immunohistochemistry (IHC) VEGF, transforming growth factor-β (TGF-β), fibroblast growth factor (FGF) and histopathology were analysed on the wounds of rats...
April 2024: Clinical and Experimental Pharmacology & Physiology
keyword
keyword
164607
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.