keyword
https://read.qxmd.com/read/37571849/sars-cov-2-reinfection-cases-in-a-household-based-prospective-cohort-in-rio-de-janeiro
#21
JOURNAL ARTICLE
Stephanie L S Penetra, Heloisa F P Santos, Paola Cristina Resende, Leonardo Soares Bastos, Michele F B da Silva, Anielle Pina-Costa, Renata Serrano Lopes, Leonardo Saboia-Vahia, Any Caroline Alves de Oliveira, Elisa Cavalcante Pereira, Fernando Medeiros Filho, Mayumi D Wakimoto, Guilherme A Calvet, Trevon L Fuller, Jimmy Whitworth, Christopher Smith, Karin Nielsen-Saines, Marilia Sá Carvalho, Otávio M Espíndola, Lusiele Guaraldo, Marilda M Siqueira, Patricia Brasil
This was a household-based prospective cohort study conducted in Rio de Janeiro, in which people with laboratory-confirmed Covid-19 and their household contacts were followed from April 2020 through June 2022. Ninety-eight reinfections were identified, with 71 (72.5%) confirmed by genomic analyses and lineage definition in both infections. During the pre-Omicron period, one dose of any Covid-19 vaccine was associated with a reduced risk of reinfection, but during the Omicron period not even booster vaccines had this effect...
August 12, 2023: Journal of Infectious Diseases
https://read.qxmd.com/read/37443699/performance-evaluation-of-vidas-%C3%A2-diagnostic-assays-detecting-anti-chikungunya-virus-igm-and-igg-antibodies-an-international-study
#22
JOURNAL ARTICLE
Geovana M Pereira, Erika R Manuli, Laurie Coulon, Marina F Côrtes, Mariana S Ramundo, Loïc Dromenq, Audrey Larue-Triolet, Frédérique Raymond, Carole Tourneur, Carolina Dos Santos Lázari, Patricia Brasil, Ana Maria Bispo de Filippis, Glaucia Paranhos-Baccalà, Alice Banz, Ester C Sabino
Chikungunya (CHIK) is a debilitating mosquito-borne disease with an epidemiology and early clinical symptoms similar to those of other arboviruses-triggered diseases such as dengue or Zika. Accurate and rapid diagnosis of CHIK virus (CHIKV) infection is therefore challenging. This international study evaluated the performance of the automated VIDAS® anti-CHIKV IgM and IgG assays compared to that of manual competitor IgM and IgG ELISA for the detection of anti-CHIKV IgM and IgG antibodies in 660 patients with suspected CHIKV infection...
July 7, 2023: Diagnostics
https://read.qxmd.com/read/37377304/factors-associated-with-post-mortem-notification-of-tuberculosis-cases-in-brazil-2014
#23
JOURNAL ARTICLE
Ursila Manga Aridja, Marli Souza Rocha, Patrícia Bartholomay, Daniele Maria Pelissari, Daiane Alves da Silva, Katia Crestine Poças, Elisabeth Carmen Duarte
According to the World Health Organization (WHO), 1.6 million deaths and 10.6 million cases of tuberculosis (TB) were reported worldwide in 2021. If treated opportunely with the recommended therapy, 85% of patients with TB are healed. The occurrence of death from TB without prior notification of the disease indicates failure in the timely access to this effective treatment. Therefore, this study aimed to identify TB cases with post-mortem notification in Brazil. This is a nested case-control study using a cohort of new TB cases reported to the Braziliam Information System for Notificable Diseases (SINAN)...
2023: Cadernos de Saúde Pública
https://read.qxmd.com/read/37333041/novel-nonablative-radiofrequency-approach-for-the-treatment-of-anal-incontinence-a-phase-1-clinical-trial
#24
JOURNAL ARTICLE
Patrícia Lordêlo, Juliana Barros, Claudia Liony, Cristiane Maria Carvalho C Dias, Janine Ferreira, Priscila G Januário, Luana N Matos, Camila O Muniz, Laizza S Silva, Cristina Brasil
OBJECTIVE: We aimed to describe the action, impact on quality of life, and side effects of perianal nonablative radiofrequency (RF) application in the treatment of anal incontinence (AI) in women. METHODS: This was a pilot, randomized clinical trial conducted between January and October 2016. We enrolled women who consecutively attended the Attention Center of the Pelvic Floor (CAAP) with complaints of AI for more than six months. Nonablative RF was applied to the perianal region of the participants using Spectra G2 (Tonederm®, Rio Grande do Sul, Brazil)...
June 2023: Curēus
https://read.qxmd.com/read/37331214/covid-19-outcomes-in-people-living-with-hiv-peering-through-the-waves
#25
EDITORIAL
Thaís Lorenna Souza Sales, Maíra Viana Rego Souza-Silva, Polianna Delfino-Pereira, João Victor Baroni Neves, Manuela Furtado Sacioto, Vivian Costa Morais de Assis, Helena Duani, Neimy Ramos de Oliveira, Natália da Cunha Severino Sampaio, Lucas Emanuel Ferreira Ramos, Alexandre Vargas Schwarzbold, Alzira de Oliveira Jorge, Ana Luiza Bahia Alves Scotton, Bruno Mateus de Castro, Carla Thais Cândida Alves da Silva, Carolina Marques Ramos, Fernando Anschau, Fernando Antonio Botoni, Genna Maira Santos Grizende, Guilherme Fagundes Nascimento, Karen Brasil Ruschel, Luanna Silva Monteiro Menezes, Luís César de Castro, Luiz Antônio Nasi, Marcelo Carneiro, Mariana Frizzo de Godoy, Matheus Carvalho Alves Nogueira, Milton Henriques Guimarães Júnior, Patricia Klarmann Ziegelmann, Rafaela Charão de Almeida, Saionara Cristina Francisco, Sidney Teodoro Silveira Neto, Silvia Ferreira Araújo, Thiago Junqueira Avelino-Silva, Márlon Juliano Romero Aliberti, Magda Carvalho Pires, Eduardo Sérgio da Silva, Milena Soriano Marcolino
OBJECTIVE: To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. METHODS: This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1)...
2023: Clinics
https://read.qxmd.com/read/37327193/the-role-of-children-in-household-transmission-of-sars-cov-2-across-four-waves-of-the-pandemic
#26
JOURNAL ARTICLE
Trevon L Fuller, Leonardo Bastos, Marilia Sá Carvalho, Paola Cristina Resende, Luana Damasceno, Oswaldo Gonçalves Cruz, Fernando Medeiros, Guilherme Calvet, Lusiele Guaraldo, Karin Nielsen-Saines, James Whitworth, Christopher Smith, Marilda Siqueira, Patrícia Brasil
BACKGROUND: It is important to understand the dynamics of SARS-CoV-2 transmission in close-contact settings such as households. We hypothesized that children would most often acquire SARS-CoV-2 from a symptomatic adult caregiver. METHODS: This prospective cohort study was conducted from April 2020 to July 2022 in a low-resource, urban settlement in Brazil. We recruited families who brought their children to a public clinic. We collected nasopharyngeal and oral swabs from household members and tracked symptoms and vaccination...
June 16, 2023: Journal of the Pediatric Infectious Diseases Society
https://read.qxmd.com/read/37280651/correction-development-and-validation-of-the-mmcd-score-to-predict-kidney-replacement-therapy-in-covid-19-patients
#27
Flávio de Azevedo Figueiredo, Lucas Emanuel Ferreira Ramos, Rafael Tavares Silva, Daniela Ponce, Rafael Lima Rodrigues de Carvalho, Alexandre Vargas Schwarzbold, Amanda de Oliveira Maurílio, Ana Luiza Bahia Alves Scotton, Andresa Fontoura Garbini, Bárbara Lopes Farace, Bárbara Machado Garcia, Carla Thais Cândida Alves da Silva, Christiane Corrêa Rodrigues Cimini, Cíntia Alcantara de Carvalho, Cristiane Dos Santos Dias, Daniel Vitório Silveira, Euler Roberto Fernandes Manenti, Evelin Paola de Almeida Cenci, Fernando Anschau, Fernando Graça Aranha, Filipe Carrilho de Aguiar, Frederico Bartolazzi, Giovanna Grunewald Vietta, Guilherme Fagundes Nascimento, Helena Carolina Noal, Helena Duani, Heloisa Reniers Vianna, Henrique Cerqueira Guimarães, Joice Coutinho de Alvarenga, José Miguel Chatkin, Júlia Drumond Parreiras de Morais, Juliana Machado-Rugolo, Karen Brasil Ruschel, Karina Paula Medeiros Prado Martins, Luanna Silva Monteiro Menezes, Luciana Siuves Ferreira Couto, Luís César de Castro, Luiz Antônio Nasi, Máderson Alvares de Souza Cabral, Maiara Anschau Floriani, Maíra Dias Souza, Maira Viana Rego Souza-Silva, Marcelo Carneiro, Mariana Frizzo de Godoy, Maria Aparecida Camargos Bicalho, Maria Clara Pontello Barbosa Lima, Márlon Juliano Romero Aliberti, Matheus Carvalho Alves Nogueira, Matheus Fernandes Lopes Martins, Milton Henriques Guimarães-Júnior, Natália da Cunha Severino Sampaio, Neimy Ramos de Oliveira, Patricia Klarmann Ziegelmann, Pedro Guido Soares Andrade, Pedro Ledic Assaf, Petrônio José de Lima Martelli, Polianna Delfino-Pereira, Raphael Castro Martins, Rochele Mosmann Menezes, Saionara Cristina Francisco, Silvia Ferreira Araújo, Talita Fischer Oliveira, Thainara Conceição de Oliveira, Thaís Lorenna Souza Sales, Thiago Junqueira Avelino-Silva, Yuri Carlotto Ramires, Magda Carvalho Pires, Milena Soriano Marcolino
No abstract text is available yet for this article.
June 6, 2023: BMC Medicine
https://read.qxmd.com/read/37255159/-common-mental-disorders-in-rural-quilombolas-in-the-north-of-minas-gerais-brazil
#28
JOURNAL ARTICLE
Patrícia de Sousa Fernandes Queiroz, João Felício Rodrigues Neto, Leonardo de Paula Miranda, Pâmela Scarlatt Durães Oliveira, Marise Fagundes Silveira, Ricardo Jardim Neiva
The scope of this article is to assess the prevalence and factors associated with Common Mental Disorders (CMD) in "quilombolas" (Afro-Brazilian residents of quilombo settlements) in rural communities located in the North of Minas Gerais, Brazil. It is a cross-sectional study of 2019 based on structured interviews and application of a Self-Reporting Questionnaire (SRQ-20). Binary logistic regression was conducted. The prevalence of CMD was 38.7%. There was a higher preponderance of CMD among female quilombolas (OR: 2...
June 2023: Ciência & Saúde Coletiva
https://read.qxmd.com/read/37243238/infectious-sars-cov-2-particles-from-rectal-swab-samples-from-covid-19-patients-in-brazil
#29
JOURNAL ARTICLE
Ieda Pereira Ribeiro, Lilian Gonçalves do Nascimento, Luis Fernando Lopez Tort, Elisa Cavalcante Pereira, Lidiane Souza Raphael Menezes, Fabio Correia Malta, Barbara Cristina Euzebio Pereira Dias de Oliveira, João Paulo Rodrigues, Pedro Paulo de Abreu Manso, Marcelo Pelajo, Myrna Cristina Bonaldo, Paola Cristina Resende Silva, Marilda Mendonça Siqueira, Patricia Brasil, Tulio Machado Fumian
The main objective of this study was to investigate the dynamic of SARS-CoV-2 viral excretion in rectal swab (RS), saliva, and nasopharyngeal swab (NS) samples from symptomatic patients and asymptomatic contacts. In addition, in order to evaluate the replication potential of SARS-CoV-2 in the gastrointestinal (GI) tract and the excretion of infectious SARS-CoV-2 from feces, we investigated the presence of subgenomic nucleoprotein gene (N) mRNA (sgN) in RS samples and cytopathic effects in Vero cell culture...
May 11, 2023: Viruses
https://read.qxmd.com/read/37242401/-plasmodium-falciparum-chloroquine-pfcrt-resistant-haplotypes-in-brazilian-endemic-areas-four-decades-after-cq-withdrawn
#30
JOURNAL ARTICLE
Rebecca de Abreu-Fernandes, Natália Ketrin Almeida-de-Oliveira, Bianca Ervatti Gama, Larissa Rodrigues Gomes, Aline Rosa De Lavigne Mello, Lucas Tavares de Queiroz, Jacqueline de Aguiar Barros, Maria das Graças Costa Alecrim, Rodrigo Medeiros de Souza, Lilian Rose Pratt-Riccio, Patrícia Brasil, Cláudio Tadeu Daniel-Ribeiro, Maria de Fátima Ferreira-da-Cruz
(1) Background: Malaria is a public health problem worldwide. Despite global efforts to control it, antimalarial drug resistance remains a great challenge. In 2009, our team identified, for the first time in Brazil, chloroquine (CQ)-susceptible Plasmodium falciparum parasites in isolates from the Brazilian Amazon. The present study extends those observations to include survey samples from 2010 to 2018 from the Amazonas and Acre states for the purpose of tracking pfcrt molecular changes in P. falciparum parasites...
May 17, 2023: Pathogens
https://read.qxmd.com/read/37224837/still-on-the-brazilian-response-to-the-microcephaly-epidemic-a-meta-analysis-of-1-548-pregnant-women-from-13-cohorts-to-evaluate-the-risk-of-adverse-outcomes
#31
JOURNAL ARTICLE
Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda-Filho, Flor Ernestina Martinez-Espinoza, Patrícia Brasil
No abstract text is available yet for this article.
April 2023: Revista Brasileira de Ginecologia e Obstetrícia
https://read.qxmd.com/read/37194879/suicide-among-women-in-brazil-a-necessary-discussion-from-a-gender-perspective
#32
JOURNAL ARTICLE
Eder Samuel Oliveira Dantas, Karina Cardoso Meira, Juliana Bredemeier, Karla Patrícia Cardoso Amorim
Suicide among women is a matter of public health, and there is a lack of scientific literature on this issue. In this theoretical essay, we sought to discuss suicide among women in Brazil from a gender perspective. For that purpose, we adopted the idea that gender extrapolates the concept of sex, considering that differences between people are produced by culture and arrangements through which society transforms biological sexuality into the realizations of human life. Therefore, this article is organized in a way to indicate some explanatory models of suicide among women, discussing gender inequalities and approaching the matter of intersectionality from a protective view...
May 2023: Ciência & Saúde Coletiva
https://read.qxmd.com/read/37156846/reduced-ability-to-neutralize-the-omicron-variant-among-adults-after-infection-and-complete-vaccination-with-bnt162b2-chadox1-or-coronavac-and-heterologous-boosting
#33
JOURNAL ARTICLE
Otávio Melo Espíndola, Trevon L Fuller, Mia Ferreira de Araújo, Luis Fernando Lopez Tort, Lusiele Guaraldo, Guilherme Calvet, Paola Resende, Myrna Bonaldo, Jimmy Whitworth, Chris Smith, Marilda Siqueira, Patrícia Brasil
COVID-19 vaccines have dramatically reduced rates of severe infection requiring hospitalization. However, SARS-CoV-2 variants have reduced vaccine effectiveness at preventing any symptomatic infection. This real-world study analyzed binding and neutralizing antibodies generated after complete vaccination and boosting across three vaccine platforms. Binding antibodies decayed most slowly in people under 60 with hybrid immunity. Neutralizing antibodies against Omicron BA.1 were reduced compared to other variants...
May 8, 2023: Scientific Reports
https://read.qxmd.com/read/37153097/assessment-of-risk-scores-to-predict-mortality-of-covid-19-patients-admitted-to-the-intensive-care-unit
#34
JOURNAL ARTICLE
Matheus Carvalho Alves Nogueira, Vandack Nobre, Magda Carvalho Pires, Lucas Emanuel Ferreira Ramos, Yara Cristina Neves Marques Barbosa Ribeiro, Rubia Laura Oliveira Aguiar, Flavia Maria Borges Vigil, Virginia Mara Reis Gomes, Camila de Oliveira Santos, Davi Mesquita Miranda, Pamela Andrea Alves Durães, Josiane Moreira da Costa, Alexandre Vargas Schwarzbold, Angélica Gomides Dos Reis Gomes, Bruno Porto Pessoa, Carolina Cunha Matos, Christiane Corrêa Rodrigues Cimini, Cíntia Alcântara de Carvalho, Daniela Ponce, Euler Roberto Fernandes Manenti, Evelin Paola de Almeida Cenci, Fernando Anschau, Flávia Carvalho Cardoso Costa, Francine Janaina Magalhães Nascimento, Frederico Bartolazzi, Genna Maira Santos Grizende, Heloisa Reniers Vianna, Jomar Cristeli Nepomuceno, Karen Brasil Ruschel, Liege Barella Zandoná, Luís César de Castro, Maíra Dias Souza, Marcelo Carneiro, Maria Aparecida Camargos Bicalho, Mariana do Nascimento Vilaça, Naiara Patrícia Fagundes Bonardi, Neimy Ramos de Oliveira, Raquel Lutkmeier, Saionara Cristina Francisco, Silvia Ferreira Araújo, Polianna Delfino-Pereira, Milena Soriano Marcolino
OBJECTIVES: To assess the ABC2 -SPH score in predicting COVID-19 in-hospital mortality, during intensive care unit (ICU) admission, and to compare its performance with other scores (SOFA, SAPS-3, NEWS2, 4C Mortality Score, SOARS, CURB-65, modified CHA2DS2-VASc, and a novel severity score). MATERIALS AND METHODS: Consecutive patients (≥ 18 years) with laboratory-confirmed COVID-19 admitted to ICUs of 25 hospitals, located in 17 Brazilian cities, from October 2020 to March 2022, were included...
2023: Frontiers in Medicine
https://read.qxmd.com/read/37147601/accuracy-of-saliva-for-sars-cov-2-detection-in-outpatients-and-their-household-contacts-during-the-circulation-of-the-omicron-variant-of-concern
#35
JOURNAL ARTICLE
Guilherme Calvet, Maria Ogrzewalska, Wagner Tassinari, Lusiele Guaraldo, Paola Resende, Trevon Fuller, Stephanie Penetra, Michele Borges, Anielle Pina-Costa, Ezequias Martins, Isabella Moraes, Heloisa Santos, Luana Damasceno, Fernando Medeiros-Filho, Otavio Espindola, Fernando Mota, Valéria Nacife, Alex Pauvolid-Corrêa, Jimmy Whitworth, Chris Smith, Marilda Siqueira, Patrícia Brasil
BACKGROUND: While nasopharyngeal (NP) swabs are considered the gold standard for severe acute respiratory coronavirus 2 (SARS-CoV-2) real-time reverse transcriptase-polymerase chain reaction (RT-PCR) detection, several studies have shown that saliva is an alternative specimen for COVID-19 diagnosis and screening. METHODS: To analyze the utility of saliva for the diagnosis of COVID-19 during the circulation of the Omicron variant, participants were enrolled in an ongoing cohort designed to assess the natural history of SARS-CoV-2 infection in adults and children...
May 5, 2023: BMC Infectious Diseases
https://read.qxmd.com/read/37147348/sars-cov-2-intra-host-diversity-antibody-response-and-disease-severity-after-reinfection-by-the-variant-of-concern-gamma-in-brazil
#36
JOURNAL ARTICLE
Felipe Gomes Naveca, Valdinete Alves Nascimento, Fernanda Nascimento, Maria Ogrzewalska, Alex Pauvolid-Corrêa, Mia Ferreira Araújo, Ighor Arantes, Érika Rocha Batista, Alessandro Álvares Magalhães, Fernando Vinhal, Tirza Peixoto Mattos, Irina Riediger, Maria do Carmo Debur, Beatriz Grinsztejn, Valdiléa G Veloso, Patrícia Brasil, Rodrigo Ribeiro Rodrigues, Darcita Buerger Rovaris, Sandra Bianchini Fernandes, Cristiano Fernandes, João Hugo Abdalla Santos, Lígia Fernandes Abdalla, Rubens Costa-Filho, Marineide Silva, Victor Souza, Ágatha Araújo Costa, Matilde Mejía, Maria Júlia Brandão, Luciana Fé Gonçalves, George Allan Silva, Michele Silva de Jesus, Karina Pessoa, André de Lima Guerra Corado, Debora Camila Gomes Duarte, Ana Beatriz Machado, Ketiuce de Azevedo Zukeram, Natalia Valente, Renata Serrano Lopes, Elisa Cavalcante Pereira, Luciana Reis Appolinario, Alice Sampaio Rocha, Luis Fernando Lopez Tort, Tsuyoshi Sekizuka, Kentaro Itokawa, Masanori Hashino, Makoto Kuroda, Filipe Zimmer Dezordi, Gabriel Luz Wallau, Edson Delatorre, Tiago Gräf, Marilda Mendonça Siqueira, Gonzalo Bello, Paola Cristina Resende
The rapid spread of the SARS-CoV-2 Variant of Concern (VOC) Gamma in Amazonas during early 2021 fueled a second large COVID-19 epidemic wave and raised concern about the potential role of reinfections. Very few cases of reinfection associated with the VOC Gamma have been reported to date, and their potential impact on clinical, immunological, and virological parameters remains largely unexplored. Here we describe 25 cases of SARS-CoV-2 reinfection in Brazil. SARS-CoV-2 genomic analysis confirmed that individuals were primo-infected with distinct viral lineages between March and December 2020 (B...
May 5, 2023: Scientific Reports
https://read.qxmd.com/read/37011087/challenges-of-acute-febrile-illness-diagnosis-in-a-national-infectious-diseases-center-in-rio-de-janeiro-16-year-experience-of-syndromic-surveillance
#37
JOURNAL ARTICLE
Clarisse da Silveira Bressan, Maria de Lourdes Benamor Teixeira, Maria Isabel Fragoso da Silveira Gouvêa, Anielle de Pina-Costa, Heloísa Ferreira Pinto Santos, Guilherme Amaral Calvet, Otilia Lupi, Andre Machado Siqueira, Rogério Valls-de-Souza, Clarissa Valim, Patrícia Brasil
INTRODUCTION: Acute febrile illnesses (AFI) are a frequent chief complaint in outpatients. Because the capacity to investigate the causative pathogen of AFIs is limited in low- and middle-income countries, patient management may be suboptimal. Understanding the distribution of causes of AFI can improve patient outcomes. This study aims to describe the most common etiologies diagnosed over a 16-years period in a national reference center for tropical diseases in a large urban center in Rio de Janeiro, Brazil...
April 3, 2023: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/36888856/environmental-risk-caused-by-drug-waste-in-the-city-of-rio-de-janeiro-brazil-during-the-sars-cov19-pandemic
#38
JOURNAL ARTICLE
Carla Patricia Figueiredo Antunes de Souza, Débora Cynamon Kligerman, Giselle Mendes Bezerra, Jaime Lopes da Mota Oliveira
The relationship between the distribution of medicines used in the Pandemic by SARS-COV-19 in the municipality of Rio de Janeiro and the estimated level of environmental risk caused by their residues was evaluated. The amount of medicines distributed by primary health care (PHC) units between 2019 and 2021 were collected. The risk quotient (RQ) corresponded to the ratio between the estimated predictive environmental concentration (PECest) obtained by the consumption and excretion of each drug and its non-effective predictive concentration (PNEC)...
March 2023: Ciência & Saúde Coletiva
https://read.qxmd.com/read/36859446/potential-and-limitations-of-machine-meta-learning-ensemble-methods-for-predicting-covid-19-mortality-in-a-large-inhospital-brazilian-dataset
#39
JOURNAL ARTICLE
Bruno Barbosa Miranda de Paiva, Polianna Delfino Pereira, Claudio Moisés Valiense de Andrade, Virginia Mara Reis Gomes, Maira Viana Rego Souza-Silva, Karina Paula Medeiros Prado Martins, Thaís Lorenna Souza Sales, Rafael Lima Rodrigues de Carvalho, Magda Carvalho Pires, Lucas Emanuel Ferreira Ramos, Rafael Tavares Silva, Alessandra de Freitas Martins Vieira, Aline Gabrielle Sousa Nunes, Alzira de Oliveira Jorge, Amanda de Oliveira Maurílio, Ana Luiza Bahia Alves Scotton, Carla Thais Candida Alves da Silva, Christiane Corrêa Rodrigues Cimini, Daniela Ponce, Elayne Crestani Pereira, Euler Roberto Fernandes Manenti, Fernanda d'Athayde Rodrigues, Fernando Anschau, Fernando Antônio Botoni, Frederico Bartolazzi, Genna Maira Santos Grizende, Helena Carolina Noal, Helena Duani, Isabela Moraes Gomes, Jamille Hemétrio Salles Martins Costa, Júlia di Sabatino Santos Guimarães, Julia Teixeira Tupinambás, Juliana Machado Rugolo, Joanna d'Arc Lyra Batista, Joice Coutinho de Alvarenga, José Miguel Chatkin, Karen Brasil Ruschel, Liege Barella Zandoná, Lílian Santos Pinheiro, Luanna Silva Monteiro Menezes, Lucas Moyses Carvalho de Oliveira, Luciane Kopittke, Luisa Argolo Assis, Luiza Margoto Marques, Magda Cesar Raposo, Maiara Anschau Floriani, Maria Aparecida Camargos Bicalho, Matheus Carvalho Alves Nogueira, Neimy Ramos de Oliveira, Patricia Klarmann Ziegelmann, Pedro Gibson Paraiso, Petrônio José de Lima Martelli, Roberta Senger, Rochele Mosmann Menezes, Saionara Cristina Francisco, Silvia Ferreira Araújo, Tatiana Kurtz, Tatiani Oliveira Fereguetti, Thainara Conceição de Oliveira, Yara Cristina Neves Marques Barbosa Ribeiro, Yuri Carlotto Ramires, Maria Clara Pontello Barbosa Lima, Marcelo Carneiro, Adriana Falangola Benjamin Bezerra, Alexandre Vargas Schwarzbold, André Soares de Moura Costa, Barbara Lopes Farace, Daniel Vitorio Silveira, Evelin Paola de Almeida Cenci, Fernanda Barbosa Lucas, Fernando Graça Aranha, Gisele Alsina Nader Bastos, Giovanna Grunewald Vietta, Guilherme Fagundes Nascimento, Heloisa Reniers Vianna, Henrique Cerqueira Guimarães, Julia Drumond Parreiras de Morais, Leila Beltrami Moreira, Leonardo Seixas de Oliveira, Lucas de Deus Sousa, Luciano de Souza Viana, Máderson Alvares de Souza Cabral, Maria Angélica Pires Ferreira, Mariana Frizzo de Godoy, Meire Pereira de Figueiredo, Milton Henriques Guimarães-Junior, Mônica Aparecida de Paula de Sordi, Natália da Cunha Severino Sampaio, Pedro Ledic Assaf, Raquel Lutkmeier, Reginaldo Aparecido Valacio, Renan Goulart Finger, Rufino de Freitas, Silvana Mangeon Meirelles Guimarães, Talita Fischer Oliveira, Thulio Henrique Oliveira Diniz, Marcos André Gonçalves, Milena Soriano Marcolino
The majority of early prediction scores and methods to predict COVID-19 mortality are bound by methodological flaws and technological limitations (e.g., the use of a single prediction model). Our aim is to provide a thorough comparative study that tackles those methodological issues, considering multiple techniques to build mortality prediction models, including modern machine learning (neural) algorithms and traditional statistical techniques, as well as meta-learning (ensemble) approaches. This study used a dataset from a multicenter cohort of 10,897 adult Brazilian COVID-19 patients, admitted from March/2020 to November/2021, including patients [median age 60 (interquartile range 48-71), 46% women]...
March 1, 2023: Scientific Reports
https://read.qxmd.com/read/36851651/ecological-genetic-and-phylogenetic-aspects-of-yfv-2017-2019-spread-in-rio-de-janeiro-state
#40
JOURNAL ARTICLE
Ieda Pereira Ribeiro, Edson Delatorre, Filipe Vieira Santos de Abreu, Alexandre Araújo Cunha Dos Santos, Nathália Dias Furtado, Anielly Ferreira-de-Brito, Anielle de Pina-Costa, Maycon Sebastião Alberto Santos Neves, Márcia Gonçalves de Castro, Monique de Albuquerque Motta, Patricia Brasil, Ricardo Lourenço-de-Oliveira, Myrna Cristina Bonaldo
In Brazil, a yellow fever (YF) outbreak was reported in areas considered YF-free for decades. The low vaccination coverage and the increasing forest fragmentation, with the wide distribution of vector mosquitoes, have been related to yellow fever virus (YFV) transmission beyond endemic areas since 2016. Aiming to elucidate the molecular and phylogenetic aspects of YFV spread on a local scale, we generated 43 new YFV genomes sampled from humans, non-human primates (NHP), and primarily, mosquitoes from highly heterogenic areas in 15 localities from Rio de Janeiro (RJ) state during the YFV 2016-2019 outbreak in southeast Brazil...
February 4, 2023: Viruses
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