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Postprandial lipemia

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https://read.qxmd.com/read/30763169/inactivity-induces-resistance-to-the-metabolic-benefits-following-acute-exercise
#1
John D Akins, Charles K Crawford, Heath M Burton, Anthony S Wolfe, Emre Vardarli, Edward F Coyle
Acute exercise improves postprandial lipemia, glucose tolerance, and insulin sensitivity, all of which are risk factors for cardiovascular disease. However, recent research suggests that prolonged sedentary behavior might abolish these healthy metabolic benefits. Accordingly, this study aimed to elucidate the impact of an acute bout of exercise on postprandial plasma triglyceride, glucose, and insulin concentrations after four days of prolonged sitting (~13.5 hrs/day). METHODS: Ten untrained to recreationally active men (n=5) and women (n=5) completed a counterbalanced, crossover study...
February 14, 2019: Journal of Applied Physiology
https://read.qxmd.com/read/30759235/meals-with-similar-fat-content-from-different-dairy-products-induce-different-postprandial-triglyceride-responses-in-healthy-adults-a-randomized-controlled-cross-over-trial
#2
Patrik Hansson, Kirsten B Holven, Linn K L Øyri, Hilde K Brekke, Anne S Biong, Gyrd O Gjevestad, Ghulam S Raza, Karl-Heinz Herzig, Magne Thoresen, Stine M Ulven
Background: Postprandial lipemia is a risk factor for cardiovascular disease. Dairy products differ in nutrient content and food matrix, and little is known about how different dairy products affect postprandial triglyceride (TG) concentrations. Objective: We investigated the effect of meals with similar amounts of fat from different dairy products on postprandial TG concentrations over 6 h in healthy adults. Methods: A randomized controlled cross-over study was performed on 47 subjects (30% men), with median (25th-75th percentile) age of 32 (25-46) y and body mass index of 23...
February 13, 2019: Journal of Nutrition
https://read.qxmd.com/read/30717491/can-carob-fruit-extract-enriched-meat-improve-the-lipoprotein-profile-vldl-oxidation-and-ldl-receptor-levels-induced-by-an-atherogenic-diet-in-stz-nad-diabetic-rats
#3
Adrián Macho-González, Alba Garcimartín, María Elvira López-Oliva, Baltasar Ruiz-Roso, Isabel Martín de la Torre, Sara Bastida, Juana Benedí, Francisco José Sánchez-Muniz
Carob fruit extract (CFE) has shown remarkable in vitro antioxidant properties and reduces postprandial hyperglycemia and hyperlipidemia in healthy animals. Development of functional meat products that contain bioactive components are presented as a great nutritional strategy. Until now, the effect of the consumption of restructured meat enriched with CFE in a murine model of diabetes has not been investigated. The objective of this study was to evaluate the effect on glycemia, lipemia, lipoprotein profile, Ldlr , arylesterase (AE), and very low-density lipoproteins (VLDL) and liver oxidation in streptozotocin-nicotinamide (STZ-NAD) growing Wistar diabetic rats fed restructured meat in the frame of a high cholesterol/high saturated-fat diet...
February 3, 2019: Nutrients
https://read.qxmd.com/read/30696504/a-single-day-of-mixed-macronutrient-overfeeding-does-not-elicit-compensatory-appetite-or-energy-intake-responses-but-exaggerates-postprandial-lipemia-during-the-next-day-in-healthy-young-men
#4
Kevin Deighton, Andy J King, Jamie Matu, Oliver M Shannon, Oliver Whiteman, Alice Long, Matthew D Huby, Miroslav Sekula, Adrian Holliday
No abstract text is available yet for this article.
January 30, 2019: British Journal of Nutrition
https://read.qxmd.com/read/30681036/effect-of-night-time-eating-on-postprandial-triglyceride-metabolism-in-healthy-adults-a-systematic-literature-review
#5
Maxine P Bonham, Elleni Kaias, Iona Zimberg, Gloria K W Leung, Rochelle Davis, Tracey L Sletten, Hazel Windsor-Aubrey, Catherine E Huggins
Eating at night time, as is frequent in shift workers, may contribute to increased cardiovascular disease (CVD) risk through a disruption in usual lipid metabolism, resulting in repeated and sustained hyperlipidemia at night. This systematic review aimed to investigate the impact of eating a meal at night compared with the same meal eaten during the day on postprandial lipemia. Six databases were searched: CINAHL Plus, Cochrane Library, EMBASE, Ovid MEDLINE, Informit, and SCOPUS. Eligible studies were original research cross-over design with a minimum fasting period of 5 h before testing preceded by a standardized control meal; measured postprandial triacylglycerol (TAG) for 5 h or greater; had meal time between 0700 h and 1600 h for day time and between 2000 h and 0400 h for night time; and had within-study test meals (food or drink) that were identical in macronutrient composition and energy...
January 25, 2019: Journal of Biological Rhythms
https://read.qxmd.com/read/30654471/validity-of-an-abbreviated-clinically-feasible-test-for-postprandial-lipemia-in-healthy-adults-a-randomized-cross-over-study
#6
Christina M Sciarrillo, Nicholas A Koemel, Stephanie P Kurti, Sam R Emerson
BACKGROUND: A large post-meal triglyceride (TG) response is an independent risk factor for cardiovascular disease, but postprandial lipemia assessments are not clinically practical in their current form. Therefore, we assessed the validity of an abbreviated, clinically feasible protocol in measuring postprandial lipemia. METHOD: Eighteen healthy adults (8 male and 10 female) completed 3 high-fat meal trials in random order: (1) a Standard in Lab (SL) protocol wherein blood draws (to determine TG) were made from a catheter at baseline and hourly for 6 h; (2) an Abbreviated in Lab (AL) protocol in which participants remained in the laboratory but blood draws were only made at baseline and 4 h post-meal; and (3) an Abbreviated with Freedom (AF) protocol in which participants vacated the laboratory between the meal and the 4-h blood draw...
January 16, 2019: Nutrients
https://read.qxmd.com/read/30553757/increased-usual-physical-activity-is-associated-with-a-blunting-of-the-triglyceride-response-to-a-high-fat-meal
#7
Braxton D Mitchell, Gurmannat Kalra, Kathleen A Ryan, Man Zhang, Carole Sztalryd, Nanette I Steinle, Simeon I Taylor, Soren Snitker, Joshua P Lewis, Michael Miller, Alan R Shuldiner, Huichun Xu
BACKGROUND: Postprandial lipemia (PPL), defined as a prolonged or elevated rise in triglycerides that accompanies fat feeding, is a significant risk factor for coronary heart disease and associated comorbidities. The impact of PPL on coronary heart disease risk is underscored by the preponderance of each day spent in the postprandial state. OBJECTIVE: In this study, we evaluated cross-sectionally the association between usual (ie, noninterventional) physical activity and the 6-hour triglyceride response to a standardized high-fat meal...
November 20, 2018: Journal of Clinical Lipidology
https://read.qxmd.com/read/30487558/extra-virgin-olive-oil-more-than-a-healthy-fat
#8
REVIEW
Elena M Yubero-Serrano, Javier Lopez-Moreno, Francisco Gomez-Delgado, Jose Lopez-Miranda
The beneficial effects of a Mediterranean diet on human health and, in particular, on lowering risk of cardiovascular disease, has been mainly attributed to its high content to extra virgin olive oil (EVOO). While its main fatty acid, oleic acid, is considered important to these effects, EVOO has other biological properties that depend on, or are potentiated by other minor components of this oil. Initially, the mechanisms considered as possible causes of this cardioprotective effect of EVOO were based on the incidence on the so-called traditional risk factors (especially lipids and blood pressure)...
November 28, 2018: European Journal of Clinical Nutrition
https://read.qxmd.com/read/30475968/long-term-consumption-of-a-mediterranean-diet-improves-postprandial-lipemia-in-patients-with-type-2-diabetes-the-cordioprev-randomized-trial
#9
Beatriz Gomez-Marin, Francisco Gomez-Delgado, Javier Lopez-Moreno, Juan F Alcala-Diaz, Rosa Jimenez-Lucena, Jose D Torres-Peña, Antonio Garcia-Rios, Ana M Ortiz-Morales, Elena M Yubero-Serrano, Maria Del Mar Malagon, Chao Q Lai, Javier Delgado-Lista, Jose M Ordovas, Jose Lopez-Miranda, Pablo Perez-Martinez
Background: Patients with type 2 diabetes (T2D) have an elevated postprandial lipemia (PPL) that has been associated with increased cardiovascular risk. Objective: We aimed to analyze whether the long-term consumption of 2 healthy dietary patterns is associated with an improvement in PPL and remnant cholesterol (RC) concentrations in patients with T2D. Design: We selected patients from the Cordioprev study who underwent oral fat load tests (FLTs) at baseline and the 3-y follow-up (241 patients with and 316 patients without T2D)...
November 1, 2018: American Journal of Clinical Nutrition
https://read.qxmd.com/read/30354257/mechanism-of-increased-ldl-low-density-lipoprotein-and-decreased-triglycerides-with-sglt2-sodium-glucose-cotransporter-2-inhibition
#10
Debapriya Basu, Lesley-Ann Huggins, Diego Scerbo, Joseph Obunike, Adam E Mullick, Paul L Rothenberg, Nicholas A Di Prospero, Robert H Eckel, Ira J Goldberg
Objective- SGLT2 (sodium-glucose cotransporter 2) inhibition in humans leads to increased levels of LDL (low-density lipoprotein) cholesterol and decreased levels of plasma triglyceride. Recent studies, however, have shown this therapy to lower cardiovascular mortality. In this study, we aimed to determine how SGLT2 inhibition alters circulating lipoproteins. Approach and Results- We used a mouse model expressing human CETP (cholesteryl ester transfer protein) and human ApoB100 (apolipoprotein B100) to determine how SGLT2 inhibition alters plasma lipoprotein metabolism...
September 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://read.qxmd.com/read/30323904/-platycodi-radix-beverage-ameliorates-postprandial-lipemia-response-through-lipid-clearance-of-triglyceride-rich-lipoprotein-a-randomized-controlled-study-in-healthy-subjects-with-a-high-fat-load
#11
Hansol Lee, Yeni Lim, Soo-Yeon Park, Soo-Muk Cho, Jeong-Sook Choe, Sewon Jeong, Jin Sook Kwak, Oran Kwon
BACKGROUND/OBJECTIVES: Elevation of postprandial lipemia characterized by a rise in triglyceride (TG)-rich lipoproteins can increase the risk of atherogenesis. The objective of this study was to investigate postprandial lipemia response to a single dietary fat/sugar load test and monitor beneficial changes induced by the consumption of Platycodi radix (AP) beverage in healthy subjects. SUBJECTS/METHODS: A total of 52 subjects were randomly assigned to either placebo or AP beverage group with a high-fat shake in a randomized controlled crossover trial...
October 2018: Nutrition Research and Practice
https://read.qxmd.com/read/30213037/acute-effects-of-dietary-carbohydrate-restriction-on-glycemia-lipemia-and-appetite-regulating-hormones-in-normal-weight-to-obese-subjects
#12
RANDOMIZED CONTROLLED TRIAL
Amirsalar Samkani, Mads J Skytte, Mads N Thomsen, Arne Astrup, Carolyn F Deacon, Jens J Holst, Sten Madsbad, Jens F Rehfeld, Thure Krarup, Steen B Haugaard
Postprandial responses to food are highly dependent on the macronutrient composition of the diet. We investigated the acute effects of transition from the recommended moderately high carbohydrate (HC) diet towards a carbohydrate-reduced high-protein (CRHP) diet on postprandial glycemia, insulinemia, lipemia, and appetite-regulating hormones in non-diabetic adults. Fourteen subjects, including five males (Mean ± SD: age 62 ± 6.5; BMI 32 ± 7.6 kg/m²; hemoglobin A1c (HbA1c ) 40 ± 3.0 mmol/mol; HOMA2-IR 2...
September 12, 2018: Nutrients
https://read.qxmd.com/read/30027313/acute-and-residual-effects-of-aerobic-exercise-on-fructose-induced-postprandial-lipemia-on-lean-male-subjects
#13
Rodrigo Cauduro Oliveira Macedo, Francesco Pinto Boeno, Juliano Boufleur Farinha, Thiago Rozales Ramis, Josianne Rodrigues-Krause, Alexandra Ferreira Vieira, Jessica Queiroz, Cesar Eduardo Jacintho Moritz, Alvaro Reischak-Oliveira
PURPOSE: The addition of fructose to one or more meals daily may lead to increased postprandial lipemia (PPL). Aerobic exercise has been successful in preventing those increases; however, the duration of exercise effects is still unknown. The aim of this study was to evaluate the acute and residual effects of aerobic exercise and fructose ingestion on PPL. METHODS: Twelve young and sedentary men completed a crossover blinded randomized trial. On day 0, they performed 45 min of aerobic exercise at 60% of VO2peak , or 45 min of resting...
July 19, 2018: European Journal of Nutrition
https://read.qxmd.com/read/30021651/identification-of-a-threshold-to-discriminate-fasting-hypertriglyceridemia-with-postprandial-values
#14
Magdalena Del Rocío Sevilla-González, Carlos A Aguilar-Salinas, Liliana Muñóz-Hernández, Paloma Almeda-Valdés, Roopa Mehta, Rafael Zubirán, Omar Yaxmehen Bello-Chavolla, Donaji V Gómez-Velasco, Arsenio Vargas-Vázquez, Tannia Viveros-Ruíz, Alexandro J Martagón-Rosado, Ivette Cruz-Bautista
BACKGROUND: Postprandial lipemia is an important cardiovascular risk factor. The assessment of postprandial lipid metabolism is a newly trend that several consortiums and countries have adopted. The aim of the study is to determine a postprandial triglyceride concentration cut-off point that accurately discriminate individuals with fasting normal triglyceride concentrations from those with fasting hypertriglyceridemia. METHODS: Cross sectional population-based study...
July 18, 2018: Lipids in Health and Disease
https://read.qxmd.com/read/29962178/a-single-bout-of-exercise-reduces-postprandial-lipemia-but-has-no-delayed-effect-on-hemorheological-variables
#15
RANDOMIZED CONTROLLED TRIAL
Chih-Hui Chiu, Tsung-Jen Yang, Hong Jen Liang, Cheng-Kang Chang, Ching-Lin Wu
High plasma triglyceride (TG) concentration in fasting state could cause hemorheological abnormality, thus increasing the incidence of metabolic diseases. Exercise has been reported to effectively reduce postprandial TG response. This study aimed to investigate whether a single bout of pre-prandial exercise can affect lipemia and hemorheological variables after a high-fat meal. Nine healthy young male subjects completed two experimental trials. The subjects walked for 1 h at 50% maximal oxygen uptake (V̇O₂max) (the exercise, EX trial), or rested (the control, CON trial)...
June 2018: Chinese Journal of Physiology
https://read.qxmd.com/read/29877081/effects-of-fiber-purified-extract-of-carob-fruit-on-fat-digestion-and-postprandial-lipemia-in-healthy-rats
#16
A Macho-González, A Garcimartín, F Naes, M E López-Oliva, A Amores-Arrojo, M J González-Muñoz, S Bastida, J Benedí, F J Sánchez-Muniz
Increased postprandial lipemia is a cardiovascular disease (CVD) risk factor. Carob fruit extract (CFE) contains condensed tannins, and their intake has been inversely related to CVD. The objective was to evaluate the in vitro pancreatic lipase activity in the presence of CFE and the in vivo effect of CFE on postprandial lipemia of healthy Wistar rats in acute and subchronic digestibility studies and to relate it with changes in fat digestion and absorption. CFE significantly reduced pancreatic lipase activity...
July 5, 2018: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/29870675/impact-of-a-one-year-lifestyle-modification-program-on-cholesterol-efflux-capacities-in-men-with-abdominal-obesity-and-dyslipidemia
#17
Marjorie Boyer, Patricia L Mitchell, Paul Poirier, Natalie Alméras, Angelo Tremblay, Jean Bergeron, Jean-Pierre Després, Benoit J Arsenault
Cholesterol efflux capacities (CECs) are negatively associated with cardiovascular disease risk, irrespective of plasma high-density lipoprotein (HDL) cholesterol levels. Whether interventions targeting lifestyle improve HDL-CECs is unknown. Our objective was to determine whether improving dietary quality and increasing physical activity levels improves HDL-CECs in men with abdominal obesity and dyslipidemia. Our study sample included men (48 ± 8.5 yr) with an elevated waist circumference (≥90 cm) associated with dyslipidemia (triglycerides ≥1...
October 1, 2018: American Journal of Physiology. Endocrinology and Metabolism
https://read.qxmd.com/read/29615070/exercise-and-postprandial-lipemia-effects-on-vascular-health-in-inactive-adults
#18
RANDOMIZED CONTROLLED TRIAL
Robinson Ramírez-Vélez, María Correa-Rodríguez, Alejandra Tordecilla-Sanders, Viviana Aya-Aldana, Mikel Izquierdo, Jorge Enrique Correa-Bautista, Cristian Álvarez, Antonio Garcia-Hermoso
BACKGROUND: There is evidence to suggest that postprandial lipemia are is linked to the impairment of endothelial function, which is characterized by an imbalance between the actions of vasodilators and vasoconstrictors. The aim of this study was to determine the effects of a 12-week high-intensity training (HIT) and moderate continuous training (MCT) protocol on postprandial lipemia, vascular function and arterial stiffness in inactive adults after high-fat meal (HFM) ingestion. METHODS: A randomized clinical trial was conducted in 20 healthy, inactive adults (31...
April 3, 2018: Lipids in Health and Disease
https://read.qxmd.com/read/29580523/postprandial-lipemia-and-fecal-fat-excretion-in-rats-is-affected-by-the-calcium-content-and-type-of-milk-fat-present-in-cheddar-type-cheeses
#19
Erik Ayala-Bribiesca, Sylvie L Turgeon, Geneviève Pilon, André Marette, Michel Britten
The aim of this study was to better understand the effect of calcium on the bioavailability of milk lipids from a cheese matrix using a rat model. Cheddar-type cheeses were manufactured with one of three types of anhydrous milk fat, control, olein or stearin, and salted with or without CaCl2 . The cheeses were fed to rats and postprandial lipemia was monitored. Feces were analyzed to quantify fatty acids excreted as calcium soaps. Higher calcium concentration in cheese caused a higher and faster triacylglycerol peak in blood, except for cheeses containing stearin...
May 2018: Food Research International
https://read.qxmd.com/read/29546297/meal-fatty-acids-have-differential-effects-on-postprandial-blood-pressure-and-biomarkers-of-endothelial-function-but-not-vascular-reactivity-in-postmenopausal-women-in-the-randomized-controlled-dietary-intervention-and-vascular-function-divas-2-study
#20
Kumari M Rathnayake, Michelle Weech, Kim G Jackson, Julie A Lovegrove
Background: Elevated postprandial triacylglycerol concentrations, impaired vascular function, and hypertension are important independent cardiovascular disease (CVD) risk factors in women. However, the effects of meal fat composition on postprandial lipemia and vascular function in postmenopausal women are unknown. Objective: This study investigated the impact of sequential meals rich in saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), or n-6 (ω-6) polyunsaturated fatty acids (PUFAs) on postprandial flow-mediated dilatation (FMD; primary outcome measure), vascular function, and associated CVD risk biomarkers (secondary outcomes) in postmenopausal women...
March 1, 2018: Journal of Nutrition
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