Valentina Botondi, Ebe D'Adamo, Mario Plebani, Oriana Trubiani, Marika Perrotta, Laura Di Ricco, Cynzia Spagnuolo, Sara De Sanctis, Elisabetta Barbante, Maria Chiara Strozzi, Antonio Maconi, Francesca Gazzolo, Marta Betti, Annalisa Roveta, Gabriella Levantini, Diego Gazzolo
Perinatal sepsis constitutes a medical emergency and is still one of the major causes of mortality and morbidity. The possibility of an early diagnosis of sepsis is still debated and controversial. In particular, clinical symptoms can be hidden by the association of sepsis with other perinatal diseases and/or by therapeutic strategies performed. In this context, there is evidence that the accuracy of standard of care diagnostic parameters (i.e. blood culture, C-reactive protein, procalcitonin) can be biased by additional confounding factors (gestational age, birth-weight, acute-chronic hypoxia)...
July 26, 2022: Clinical Chemistry and Laboratory Medicine: CCLM