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Thyroid and ultrasound

Pradeep Balineni, Rekha Arcot, Kannan Devygounder, Khalilur Rahaman, Bharath Narayansamy, Manoj Prabhu, Shantini Vaitheeswaran
INTRODUCTION: Nerve sheath tumors are tumors arising from nerve sheaths or which show nerve sheath differentiation. They are divided as benign and malignant. They are associated with Von Recklinghausen syndrome. Characterised by café-au-lait spots, lisch nodules, acoustic neuromas, pheochromocytomas. PRESENTATION OF CASE: A 62 year old gentleman came with complaints of Abdominal discomfort for 1month. He also had Left sided abdominal pain, Anorexia, Vomiting, No history of dyspepsia, fever, bowel disturbance...
February 13, 2019: International Journal of Surgery Case Reports
Luca Giovanella, Gaetano Paone, Teresa Ruberto, Luca Ceriani, Pierpaolo Trimboli
BACKGROUND: Postoperative routine radioiodine (RAI) treatment is currently debated for patients with low-risk differentiated thyroid carcinoma (DTC) patients. If performed, a low ¹³¹I activity (i.e., 1 to 2 GBq) is recommended with the aim to ablate thyroid remnant and facilitate subsequent follow-up by thyroglobulin measurement. The purpose of this study was to evaluate the relationship between postsurgical technetium-99m (99m Tc)-pertechnetate scintigraphy and the rate of successful remnant ablation after low activity radioiodine ablation in patients with DTC...
February 15, 2019: Endocrinology and Metabolism
Miguel Paja, Jose Luis Del Cura, Rosa Zabala, Igone Korta, Aitziber Ugalde, José I López
OBJECTIVE: To evaluate the performance of core-needle biopsy (CNB) in thyroid using a cohort of patients in which it was used as first choice. METHODS: Our institutional review board approved this retrospective study. We reviewed all CNB performed in our center over a period of 11 years. Ultrasound-guided CNBs were performed using a spring-loaded 18-gauge biopsy needle. We used a classification with four diagnostic categories for CNB results: insufficient, benign, follicular lesion (indeterminate), and malignant...
February 19, 2019: European Radiology
Brian H H Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
OBJECTIVE: High-intensity focused ultrasound (HIFU) ablation is a promising treatment for benign thyroid nodules but single application is less effective in larger-sized nodules. We aimed to assess the efficacy and safety of two sequential applications in larger-sized nodules. METHODS: Fifty patients underwent ablation of a large-sized nodule (baseline volume ≥ 20 mL and diameter ≤ 50 mm). Thirty-one (62.0%) patients underwent single application (group I) while 19 (38...
February 18, 2019: European Radiology
Hengqiang Zhao, Hehe Li
PURPOSE: To evaluate the performance of preoperative ultrasound in the diagnosis of cervical lymph nodes metastases (CLNM) of papillary thyroid cancer (PTC) and its value in assisting cervical lymph node dissection (CLND). METHODS: PubMed, EMBASE and Cochrane Library databases were searched to identify relevant studies up to Sep. 2017. Overall sensitivity, specificity, and diagnostic odds ratio (DOR) were used to assess the diagnostic efficacy of ultrasound in detecting central and lateral CLNM of PTC...
March 2019: European Journal of Radiology
Antonin Prochazka, Sumeet Gulati, Stepan Holinka, Daniel Smutek
In recent years, several computer-aided diagnosis systems emerged for the diagnosis of thyroid gland disorders using ultrasound imaging. These systems based on machine learning algorithms may offer a second opinion to radiologists by evaluating a malignancy risk of thyroid tissue, thus increasing the overall diagnostic accuracy of ultrasound imaging. Although current computer-aided diagnosis systems exhibit promising results, their use in clinical practice is limited. One of the main limitations is that the majority of them use direction-dependent features...
January 1, 2019: Technology in Cancer Research & Treatment
Y Zhang, J X Zhang, J Shi, Y Yu, Z F Yuan, G Z Lu, Y Gao, Y M Gao, X H Guo
OBJECTIVE: To discuss the clinical characteristics and diagnostic and therapeutic considerations of primary thyroid lymphoma (PTL) by reviewing PTL cases. METHODS: In the study, 12 cases of PTL diagnosed and treated in Peking University First Hospital between January 1995 and September 2015 were identified. The clinical characteristics, management experiences and prognosis of these cases were reviewed retrospectively. RESULTS: A total of 12 PTL patients (four males and eight females) were collected, with an average age of 63 years (42 to 81 years) at the time of diagnosis...
February 18, 2019: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Martin Freesmeyer, Thomas Winkens, Christian Kühnel, Thomas Opfermann, Philipp Seifert
Side-by-side evaluation of thyroid ultrasound (US) and 99m TcO4 scintigraphy can lead to uncertainties in the correct topographic assignment of thyroid nodules. The aim of this study was to evaluate 99m TcO4 single-photon emission computed tomography/ultrasound (SPECT/US) fusion imaging. Seventy-nine patients were prospectively investigated. If conventional diagnostics of the thyroid gland (B-mode-US, scintigraphy) produced unclear findings, SPECT was performed and transferred to a US device for real-time sensor-navigated 3-D fusion US investigation...
February 14, 2019: Ultrasound in Medicine & Biology
Deng-Ke Teng, He-Qun Li, Guo-Qing Sui, Yuan-Qiang Lin, Qiang Luo, Ping Fu, Jia-Rui Du, Chun-Xiang Jin, Hui Wang
PURPOSE: To assess the safety and efficacy of microwave ablation (MWA) for primary papillary thyroid microcarcinoma (PTMC) with a large sample of 185 patients. METHODS: A total of 185 patients underwent MWA for 206 primary PTMC nodules. They received ultrasound follow-up at 1, 3, 6, and 12 months after MWA and every 6 months thereafter. Nodule volumes were calculated at each follow-up and compared with those before MWA. Additionally, the volume reduction rate (VRR) of the nodules was calculated...
February 15, 2019: Endocrine
Andrius Rybakovas, Augustinas Bausys, Andrius Matulevicius, Gytis Zaldokas, Mindaugas Kvietkauskas, Gintautas Tamulevicius, Virgilijus Beisa, Kestutis Strupas
Introduction: Recurrent laryngeal nerve injury is one of the major complications related to thyroid surgery. Intraoperative recurrent laryngeal nerve functional status monitoring is becoming a standard part of thyroid surgery. However, the current methods for intraoperative nerve functional status assessment are associated with a demand for specialized devices and increased costs. Aim: To assess the validity of a new method - intraoperative laryngeal ultrasonography - for prediction of recurrent laryngeal nerve injury...
January 2019: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
Diana Juhee Chang, Stephen S Lippman, Alison M Semrad, Bryan Volpp, Arthur L M Swislocki
Ultrasound for patients with hyperthyroidism and thyroid hot nodules is of limited value, given the high prevalence of suspicious findings, but may be useful for patients with high-risk factors.
May 2018: Federal Practitioner: for the Health Care Professionals of the VA, DoD, and PHS
Marco Khiella, Michael A Maximus, Sameh A Fayek
Renal cell carcinoma (RCC) is known for having unpredictable clinical behavior. Metastases can occur in unusual locations with a long-time lag after the treatment of the primary cancer. Despite being a sign of poor prognosis, aggressive metastasectomy may prolong survival. Presented is a case of delayed sequential metastases of RCC to the pancreas and the thyroid gland that occurred eight years after the radical nephrectomy. Both were resected. A history of remote nephrectomy for RCC is important and may be suggestive of metastatic disease...
December 1, 2018: Curēus
Adrien Ben Hamou, Stéphanie Espiard, Christine Do Cao, Miriam Ladsous, Camille Loyer, Alexandre Moerman, Samuel Boury, Maéva Kyheng, Claire-Marie Dhaenens, Vincent Tiffreau, Pascal Pigny, Gilles Lebuffe, Robert Caiazzo, Sébastien Aubert, Marie Christine Vantyghem
BACKGROUND: Myotonic dystrophy (DM1), a neuromuscular disease related to DMPK gene mutations, is associated to endocrine disorders and cancer. A routine endocrine work-up, including thyroid ultrasound (US), was conducted in 115 genetically-proven DM1 patients in a neuromuscular reference center. The aim of this study was to determine the prevalence and the causes of US thyroid abnormalities in DM1. RESULTS: In the whole population (age 45.1 ± 12.2 years, 61...
February 13, 2019: Orphanet Journal of Rare Diseases
Yang Guang, Wen He, Yukun Luo, Hongxia Zhang, Yukang Zhang, Bin Ning, Tengfei Yu
BACKGROUND: The patient satisfaction of symptoms improvement and disease factors that may affect long-term treatment efficacy of radiofrequency ablation (RFA) for non-functioning solid benign thyroid nodules (TNs) over a 2-year follow up study was investigated. METHODS: This retrospective study evaluated 194 non-functioning solid benign TNs of 103 patients. The TNs were categorized as small (≤5 ml), medium (5.1 to 13 ml), intermediate (13.1 to 30 ml) and large (over 30 ml) according to the initial volume of TNs before ablation...
February 13, 2019: BMC Cancer
Seyfullah Kan, Muhammed Kizilgul, Bulent Celik, Selvihan Beysel, Mustafa Caliskan, Mahmut Apaydin, Bekir Ucan, Erman Cakal
Nodular thyroid disease is a very common disorder in patients with acromegaly. Insulin-like growth factor-1 (IGF-1) is a thyroid growth factor, and there is a correlation between IGF-1 levels and thyroid volume (TV) in patients with acromegaly. There is no study investigating the impact of somatostatin analog (SSA) treatment on thyroid nodule volume in patients with acromegaly. We aimed to assess thyroid nodule volume change with SSA treatment in patients with persistent acromegaly. We retrospectively analyzed data from 108 consecutive patients with acromegaly who were followed up by our clinic after undergoing surgery between 2002 and 2014...
February 9, 2019: Endocrine Journal
Hye Shin Ahn, Dong Gyu Na, Jung Hwan Baek, Jin Yong Sung, Ji-Hoon Kim
BACKGROUND: To retrospectively evaluate the false negative rate of ultrasound-guided fine needle aspiration (FNA) according to the nodule size and ultrasound pattern. METHODS: We included 432 consecutive thyroid nodules from 384 patients who underwent ultrasound-guided FNA with benign results (≥1 cm). The false negative rate in the nodules was assessed according to the nodule size and ultrasound pattern based on the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS)...
February 10, 2019: Head & Neck
Pierpaolo Trimboli, Arnoldo Piccardo, Maria Alevizaki, Camilla Virili, Mehrdad Naseri, Simona Sola, Gaetano Paone, Gilles Russ, Luca Giovanella
BACKGROUND: Several ultrasound (US) risk stratification systems have been proposed for the assessment of thyroid nodules, and their performance was shown as good. However, the rate of nodules assessed at intermediate risk is not negligible and whether they should be submitted or not to further examination is still under debate. The present study aimed to evaluate the reliability of 18 F-FDG PET/CT in stratifying the risk of malignancy in these lesions. METHODS: Two institutions participated to this retrospective study in which a dedicated 18 F-FDG PET/CT was proposed to patients having a thyroid nodule with US assessment of EU-TIRADS 4 or 5...
February 11, 2019: Clinical Endocrinology
Laila Qadan, Adel Ahmed, Kusum Kapila
OBJECTIVE: Thyroid ultrasound plays a major role in the clinical management of patients with thyroid nodules. Comprehensive reporting enables malignant risk stratification and biopsy decisions. In this study, we aimed at a systematic evaluation of the content and completeness of thyroid radiology reports. METHODS: A retrospective study was undertaken. A total of 200 thyroid ultrasound reports of examinations performed over a year period were reviewed. After excluding 18 reports, the remaining 182 were evaluated for the inclusion of the following nodule characteristics: size, 3- axis dimensions, location, presence or absence of five signs suspicious of malignancy namely, micro calcification, hypoechogenecity, irregular margin, height to width ratio and intranodular vascularity...
February 10, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
Daniela Schmidt
Thyroid ultrasound is used as a first-line diagnostic procedure to evaluate thyroid nodules. Several ultrasound characteristics have been associated with an increased risk of malignancy. Based on these criteria, classification systems are being developed to categorize thyroid nodules and stratify their malignant risk to decide about further evaluation. Up to now only morphological features are taken into account. The results of Doppler ultrasonography have not yet been included in these thyroid imaging and reporting systems (TI-RADS) although predominantly internal flow is associated with malignancy of thyroid follicular neoplasia...
February 2019: Laryngo- Rhino- Otologie
Swapnil Patel, Alok A Bhatt
Congenital anterior neck masses comprise a rare group of lesions typically diagnosed in childhood. Most commonly, lesions are anomalies of the thyroglossal duct, namely the thyroglossal duct cyst, along with ectopic thyroid tissue. Although usually suspected based on clinical examination, imaging can confirm the diagnosis, assess the extent, and evaluate for associated complications. Imaging characteristics on ultrasound, CT, and MRI may at times be equivocal; differential considerations include branchial cleft cyst, dermoid/epidermoid, laryngocele, thymic cyst, lymphatic malformation, and metastatic disease...
February 6, 2019: Insights Into Imaging
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