keyword
https://read.qxmd.com/read/38340102/national-variation-in-hospital-mteer%C3%A2-outcomes-and-correlation-with%C3%A2-tavr-outcomes-sts-acc-tvt-registry-analysis
#1
JOURNAL ARTICLE
Dharam J Kumbhani, Pratik Manandhar, Anthony A Bavry, Adnan K Chhatriwalla, Jay Giri, Michael Mack, John Carroll, Ambarish Pandey, Andrzej Kosinski, Eric D Peterson, Tsuyoshi Kaneko, James A de Lemos, Sreekanth Vemulapalli
BACKGROUND: A single, multitiered valve center designation has been proposed to publicly identify centers with expertise for all valve therapies. The correlation between transcatheter aortic valve replacement (TAVR) and mitral transcatheter edge-to-edge repair (MTEER) procedures is unknown. OBJECTIVES: We sought to examine the relationship between site-level volumes and outcomes for TAVR and MTEER. We further explored variability between sites for MTEER outcomes...
January 30, 2024: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38171713/antithrombotic-therapy-for-patients%C3%A2-undergoing-cardiac-electrophysiological-and-interventional%C3%A2-procedures-jacc-state-of-the-art-review
#2
REVIEW
Luigi Di Biase, Dhanunjaya J Lakkireddy, Jacopo Marazzato, Alejandro Velasco, Juan Carlos Diaz, Rachita Navara, Jonathan Chrispin, Bharath Rajagopalan, Andrea Natale, Sanghamitra Mohanty, Xiaodong Zhang, Domenico Della Rocca, Aarti Dalal, Ki Park, Jose Wiley, Wayne Batchelor, Jim W Cheung, George Dangas, Roxana Mehran, Jorge Romero
Electrophysiological and interventional procedures have been increasingly used to reduce morbidity and mortality in patients experiencing cardiovascular diseases. Although antithrombotic therapies are critical to reduce the risk of stroke or other thromboembolic events, they can nonetheless increase the bleeding hazard. This is even more true in an aging population undergoing cardiac procedures in which the combination of oral anticoagulants and antiplatelet therapies would further increase the hemorrhagic risk...
January 2, 2024: Journal of the American College of Cardiology
https://read.qxmd.com/read/37777784/minimally-invasive-valve-surgery-including-patients-of-combined-simultaneous-surgery-a-retrospective-study
#3
JOURNAL ARTICLE
Yun Ling, Huaxin Chen, Pengxiong Zhu, Tian Li, Bangde Xue, Jun Liu
OBJECTIVE: This study investigated the perioperative safety and advantages of performing a minimally invasive valve surgery (MIVS) and conducting a preliminary examination of the combined simultaneous surgery (CSS). METHODS: A total of 29 patients (16 men and 13 women; mean age, 58.41 ± 13.08 years) who underwent MIVS at our center from July 2021 to March 2022 were selected. Among them, 16 patients underwent aortic valve surgery (AVS), 13 patients underwent mitral valve surgery (MVS), and four patients additionally underwent CSS...
September 30, 2023: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/37645030/comparative-modeling-of-the-mitral-valve-in-normal-and-prolapse-conditions
#4
JOURNAL ARTICLE
Seyed Esmail Razavi, Amin Talebi
INTRODUCTION: Computational modeling is one of the best non-invasive approaches to predicting the functional behavior of the mitral valve (MV) in health and disease. Mitral valve prolapse (MVP) due to partial or complete chordae tendineae rapture is the most common valvular disease and results in mitral regurgitation (MR). METHODS: In this study, Image-based fluid-structure interaction (FSI) models of the human MV are developed in the normal physiological and posterior leaflet prolapse conditions...
2023: BioImpacts: BI
https://read.qxmd.com/read/37632738/heart-failure-medical-therapy-prior-to-mitral-transcatheter-edge-to-edge-repair-the-sts-acc-transcatheter-valve-therapy-registry
#5
JOURNAL ARTICLE
Anubodh S Varshney, Miloni Shah, Sreekanth Vemulapalli, Andrzej Kosinski, Ankeet S Bhatt, Alexander T Sandhu, Sameer Hirji, Ersilia M DeFilippis, Pinak B Shah, Mona Fiuzat, Patrick T O'Gara, Deepak L Bhatt, Tsuyoshi Kaneko, Michael M Givertz, Muthiah Vaduganathan
BACKGROUND AND AIMS: Guideline-directed medical therapy (GDMT) is recommended prior to mitral valve transcatheter edge-to-edge repair (MTEER) in patients with heart failure (HF) and severe functional mitral regurgitation (FMR). Whether MTEER is being performed on the background of optimal GDMT in clinical practice is unknown. METHODS: Patients with left ventricular ejection fraction (LVEF) < 50% who underwent MTEER for FMR from July 23, 2019 to March 31, 2022 in the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry were identified...
August 26, 2023: European Heart Journal
https://read.qxmd.com/read/37452910/experimental-observation-on-a-new-chimney-shaped-mechanical-valve-completely-implanted-above-the-mitral-annulus-in-animals
#6
JOURNAL ARTICLE
Yongchao Yu, Fan Yang, Ming Qin, Xufeng Wei, Shangyi Yu, Dejun Gong, Guokun Wang, Hao Tang, Zhiyun Xu
Current commercially available prosthetic valves suffer from limited size, high requirements for implantation technique, subvalvular structural destruction, and valve dysfunction due to proliferation of fibrous endothelial tissue. This study aims to perform the preclinical large animal experiments for surgically implanting a chimney-shaped artificial mechanical heart valve with zero left ventricular occupancy, which fully accommodates the movement of the valve leaflets in the valve frame and realizes completely supra-annular surgical implantation...
July 15, 2023: General Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/37383697/identification-of-risk-factors-for-infection-after-mitral-valve-surgery-through-machine-learning-approaches
#7
JOURNAL ARTICLE
Ningjie Zhang, Kexin Fan, Hongwen Ji, Xianjun Ma, Jingyi Wu, Yuanshuai Huang, Xinhua Wang, Rong Gui, Bingyu Chen, Hui Zhang, Zugui Zhang, Xiufeng Zhang, Zheng Gong, Yongjun Wang
BACKGROUND: Selecting features related to postoperative infection following cardiac surgery was highly valuable for effective intervention. We used machine learning methods to identify critical perioperative infection-related variables after mitral valve surgery and construct a prediction model. METHODS: Participants comprised 1223 patients who underwent cardiac valvular surgery at eight large centers in China. The ninety-one demographic and perioperative parameters were collected...
2023: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/37346447/unmasking-of-severe-mitral-regurgitation-after-pericardiectomy
#8
Pavan Kumar Dammalapati, Sandeep Kumar Kar, Subhendu Sekhar Mahapatra
Mitral valve prolapse in the young is the most common cause of mitral regurgitation (MR). Constrictive pericarditis (CP) is a chronic and end-stage manifestation of the inflammatory process of the pericardium. Apart from equalization of diastolic pressure of the chambers as well as increased ventricular interdependence, the thickened pericardial sheath in end-stage pericarditis fails to accommodate the intrathoracic venous return due to restricted cardiac chamber filling. Intracardiac valvular pathologies might co-exist in CP...
July 2023: Indian Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/37052800/advances-in-clinical-cardiology-2022-a-summary-of-key-clinical-trials
#9
REVIEW
Patrick Savage, Brian Cox, Michael Shahmohammadi, Johnathan Foster, Ian Menown
INTRODUCTION: Over the course of 2022, numerous key clinical trials with valuable contributions to clinical cardiology were published or presented at major international conferences. This review seeks to summarise these trials and to reflect on their clinical context. METHODS: The authors reviewed clinical trials presented at major cardiology conferences during 2022, including the American College of Cardiology (ACC), European Association for Percutaneous Cardiovascular Interventions (EuroPCR), European Society of Cardiology (ESC), Transcatheter Cardiovascular Therapeutics (TCT), American Heart Association (AHA), European Heart Rhythm Association (EHRA), Society for Cardiovascular Angiography and Interventions (SCAI), TVT-The Heart Summit (TVT) and Cardiovascular Research Technologies (CRT)...
June 2023: Advances in Therapy
https://read.qxmd.com/read/37036075/anticoagulation-therapy-and-clinical-outcomes-following-transcatheter-mitral-valve-repair-for-patients-with-mitral-regurgitation-a-meta-analysis
#10
REVIEW
Jian Zhang, Yu Yang, Lin Jia, Jiannan Su, Ai Xiao, Xianhe Lin
Transcatheter mitral valve repair (TMVR) using MitraClip (MC) is now an established technique in the interventional treatment of mitral regurgitation. Common complications after MC procedure are bleeding and ischemic events. However, 2017 ESC/EACTS and 2020 ACC/AHA did not give a clear antithrombotic protocol, the policy has been based on clinical experience. Here, we performed a meta-analysis comparing outcomes with and without the addition of anticoagulants after TMVR. We searched the Cochrane Library, EMBASE, PubMed, and Web of Science from inception to October 6, 2022 to identify studies with or without the use of anticoagulants after TMVR...
June 2023: Clinical Cardiology
https://read.qxmd.com/read/36910075/relationship-between-valvular-structure-and-biochemical-indices-of-non-valvular-atrial-fibrillation-and-senile-degenerative-valvular-heart-disease
#11
JOURNAL ARTICLE
Jian-Qin Chen, Xin Zeng, Kun-Con Li, Jing-Long Huang, Bing-Li Guo, Xuan Zhou
BACKGROUND: Valvular heart disease (VHD) is a common clinical condition in geriatric-related cardiovascular diseases that is connected to heart dysfunction. Atrial fibrillation (AF) is the most frequent arrhythmia. Considering these two common clinical conditions, so far no sufficient data on the relationship between degenerative VHD and non-valvular atrial fibrillation (NVAF). We aimed to explore the relationship between valvular structure and biochemistry of nonvalvular AF and degenerative valvular heart disease in the elderly...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36633320/is-there-a-role-for-biomarkers-in-asymptomatic-severe-chronic-primary-mitral-regurgitation
#12
JOURNAL ARTICLE
Raj Verma, Gianluigi Bisleri, Geraldine Ong, Kim A Connelly
PURPOSE OF REVIEW: Chronic primary mitral regurgitation (MR) is a common heart valve disease with a rising prevalence with the aging populations worldwide. The timing of surgical intervention in patients who have severe MR but remain asymptomatic is often debated. Herein we synthesize the latest American College of Cardiology/American Heart Association (ACC/AHA) and European Society of Cardiology/ European Association for Cardio-Thoracic Surgery (ESC/EACTS) heart valve guidelines in such patients and illustrate how circulating and/or imaging biomarkers can be used to help refine decision making algorithms...
January 12, 2023: Current Opinion in Cardiology
https://read.qxmd.com/read/36421934/the-role-of-cardiovascular-magnetic-resonance-in-patients-with-mitral-regurgitation
#13
REVIEW
Anna Giulia Pavon, Marco Guglielmo, Pierpaolo Mattia Mennilli, Mariana B L Falcão, Luca Bergamaschi, David Filip Costantin, Michele Vivaldo, Laura Anna Leo, Susanne Schlossbauer, Christopher W Roy, Matthias Stuber, Giovanni Pedrazzini, Francesco Faletra
The 2019 Global Burden of Disease (GBD) study estimated that there were approximately 24.2 million people affected worldwide by degenerative mitral regurgitation (MR), resulting in 34,200 deaths. After aortic stenosis, MR is the most prevalent VHD in Europe and the second-most common VHD to pose indications for surgery in western countries. Current ESC and AHA/ACC guidelines for the management of VHD emphasize the importance of an integrative approach for the assessment of MR severity, which is of paramount importance in dictating the timing for surgery...
November 18, 2022: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/36003759/outcome-of-consistent-guideline-based-tricuspid-management-in-patients-undergoing-degenerative-mitral-regurgitation-correction
#14
JOURNAL ARTICLE
Gilles D Dreyfus, Benjamin Essayagh, Giovanni Benfari, Filip Dulguerov, Shelley Rahman Haley, Carine Dommerc, Adelin Albert, Maurice Enriquez-Sarano
Objectives: Despite coherent guidelines, management of functional tricuspid regurgitation (FTR) consequences on outcome in the context of degenerative mitral regurgitation (DMR) remains controversial due to lacking series of large magnitude with rigorous application of tricuspid guidelines and strict long-term echocardiographic follow-up. Thus, we aimed at gathering such a cohort to examine outcomes of patients undergoing DMR surgery following tricuspid surgery guidelines. Methods: All consecutive patients with isolated DMR 2005-2015 operated on with baseline FTR assessment and tricuspid annulus diameter measurement were identified...
September 2021: JTCVS open
https://read.qxmd.com/read/35971750/real-world-experience-with-concomitant-or-staged-transcatheter-aortic-and-mitral-valve-replacements-using-balloon-expandable-valves
#15
JOURNAL ARTICLE
Alan Zajarias, Susheel Kodali, James M McCabe, Marvin H Eng, Vasilis Babaliaros
OBJECTIVE: To describe outcomes of patients who underwent transcatheter aortic valve replacement (TAVR) in a native valve or failed bioprosthetic valve or transcatheter heart valve (THV) and a transcatheter mitral valve replacement procedure (TMVR; valve-in-valve [mViV], valve-in-ring [mViR], and valve in mitral annulus calcification [ViMAC]) either concomitantly (same procedure) or staged (different procedures). BACKGROUND: Patient characteristics, procedural details, and outcomes of concomitant or staged TAVR and TMVR procedures are largely unknown...
August 16, 2022: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/35967213/mitral-valve-surgery-after-failed-transcatheter-edge-to-edge-repair
#16
JOURNAL ARTICLE
Piotr Mazur, Arman Arghami, Clark Zheng, Mohamad Alkhouli, Hartzell V Schaff, Joseph Dearani, Richard C Daly, Kevin Greason, Juan A Crestanello
Objective: Mitral valve operations for failed transcatheter edge-to-edge repair (TEER) are increasing. This study investigated the indications, surgical procedures, and outcomes after surgery for failed TEER. Methods: We analyzed records of patients who underwent mitral valve operations after TEER between January 2013 and September 2021. Patient characteristics, clip number and location, indications, timing, surgery type, and outcomes were evaluated. Results: A total of 41 patients (median age, 77 years; 14 women; median Society of Thoracic Surgeons predicted risk of mortality score, 9...
August 2022: JTCVS techniques
https://read.qxmd.com/read/35606861/concomitant-use-of-sapien-3-transcatheter-valve-for-severe-mac-with-intuity-elite-rapid-deployment-valve-for-aortic-stenosis
#17
JOURNAL ARTICLE
Gareth J Hooks, Peter Ball, Mark S Spence, Reuben Jeganathan
BACKGROUND: Concomitant double valve pathology in the presence of severe MAC poses significant technical challenges when planning surgical intervention. With continued evolution of valve prosthesis, innovative techniques can be considered with the potential for additional therapeutic benefit. CASE PRESENTATION: We present a novel technique of using a rapid deployment surgical aortic valve in combination with open surgical transcatheter mitral valve implantation (TMVI) for severe Mitral Annular Calcification (MAC)...
May 23, 2022: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/35482250/advances-in-clinical-cardiology-2021-a-summary-of-key-clinical-trials
#18
REVIEW
Patrick Savage, Brian Cox, Katie Linden, Jaimie Coburn, Michael Shahmohammadi, Ian Menown
INTRODUCTION: Over the course of 2021, numerous key clinical trials with valuable contributions to clinical cardiology were published or presented at major international conferences. This review seeks to summarise these trials and reflect on their clinical context. METHODS: The authors reviewed clinical trials presented at major cardiology conferences during 2021 including the American College of Cardiology (ACC), European Association for Percutaneous Cardiovascular Interventions (EuroPCR), European Society of Cardiology (ESC), Transcatheter Cardiovascular Therapeutics (TCT), American Heart Association (AHA), European Heart Rhythm Association (EHRA), Society for Cardiovascular Angiography and Interventions (SCAI), TVT-The Heart Summit (TVT) and Cardiovascular Research Technologies (CRT)...
June 2022: Advances in Therapy
https://read.qxmd.com/read/35419432/advances-in-procedural-echocardiographic-imaging-in-transcatheter-edge-to-edge-repair-for-mitral-regurgitation
#19
REVIEW
Yiting Fan, Jeffrey Shi Kai Chan, Alex Pui-Wai Lee
Transcatheter edge-to-edge repair (TEER) therapy is recommended by the American College of Cardiology/American Heart Association (ACC/AHA) guidelines for selected patients with symptomatic severe or moderate-severe mitral regurgitation (MR). Echocardiography, in particular transesophageal echocardiography (TEE), plays a critical role in procedural planning and guidance for TEER. Recent innovations and advances in TEE techniques including three-dimensional (3D) imaging, unlimited x-plane imaging, live 3D multiplanar reconstruction, as well as transillumination imaging with color Doppler and transparency rendering have further enhanced procedural imaging for TEER, especially for complex diseases including commissural defects, clefts, and multi-segment pathologies...
2022: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/34733695/transapical-transcatheter-mitral-valve-implantation-in-patients-with-degenerated-mitral-bioprostheses-or-failed-ring-annuloplasty
#20
JOURNAL ARTICLE
Alina Zubarevich, Marcin Szczechowicz, Konstantin Zhigalov, Philipp Marx, Alexander Lind, Rolf Alexander Jánosi, Tienush Rassaf, Sharaf-Eldin Shehada, Rizwan Malik, Markus Kamler, Matthias Thielmann, Bastian Schmack, Arjang Ruhparwar, Alexander Weymann, Daniel Wendt
Background: We sought to evaluate the outcomes of transapical transcatheter mitral valve replacement in patients with degenerated mitral bioprostheses or failed mitral ring annuloplasty and high surgical risk for redo mitral valve procedure. Methods: Between August 2012 and December 2020, 41 consecutive high-risk patients underwent transcatheter mitral 'valve-in-valve' (TM-ViV, n=25) or 'valve-in-ring' (TM-ViR, n=16) implantation at our institution. All procedures were performed in a hybrid operating theater using the SAPIEN XT/3™ or the DIRECT FLOW MEDICAL™ prostheses...
September 2021: Annals of Cardiothoracic Surgery
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