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Alberto Zanetto, Monica Pellone, Marco Senzolo
In 1845, George Budd published a brief report regarding three patients who developed an obstruction of the hepatic veins. The condition has never been reported before, and was related to sepsis and alcoholism. Fifty-three years later, Hans Chiari postulated that syphilis was causing the obstruction of the hepatic veins, and enriched the debate with clinical and pathological correlations. Following the hypothesis on the "phlebitis obliterans", several authors proposed other pathophysiological explanations including congenital causes, chronic trauma, and exogenous toxins...
March 6, 2019: Liver International: Official Journal of the International Association for the Study of the Liver
William R Masch
No abstract text is available yet for this article.
February 26, 2019: Academic Radiology
Virginia Hernández-Gea, Andrea De Gottardi, Frank W G Leebeek, Pierre-Emmanuel Rautou, Riad Salem, Juan Carlos Garcia-Pagan
Budd-Chiari Syndrome (BCS) and non-cirrhotic non-tumoral portal vein thrombosis (NCPVT) are two rare disorders, with several similarities that are categorized under the term splanchnic vein thrombosis. Both disorders are frequently associated with an underlying pro-thrombotic disorder. They can cause severe portal hypertension and usually affect oung patients, negatively influencing life expectancy when the diagnosis and treatment is not done at an early stage. Yet, they have specific features that require individual considerations...
February 26, 2019: Journal of Hepatology
Vincenzo Davide Palumbo, Benedetto Di Trapani, Antonio Bruno, Mario Feo, Bernardo Molinelli, Simone Tomasini, Attilio Ignazio Lo Monte, Marianna Messina, Giovanni Tomasello
INTRODUCTION: Hepatic abscess can be defined as an encapsulated collection of suppurative material within the liver parenchyma. Hepatic abscess can be distinguished as pyogenic, amebic, or fungal. Biliary tract disease remains the most common cause of hepatic abscess today, and the most common complications range from pleural effusion, empyema, and bronchohepatic fistula to subphrenic abscess and rupture into the peritoneal cavity, stomach, colon, vena cava, or kidney. A large abscess compressing the inferior vena cava and the hepatic veins may result in Budd-Chiari syndrome...
February 25, 2019: Journal of Medical Case Reports
Jun Zhou, Yu Wang, Yiming Liu, Hanjiang Zeng, Hanshi Xu, Fan Lian
Budd-Chiari syndrome (BCS) is a rare but severe venous form of Behcet's disease (BD) that is caused by the obstruction of the venous outflow tract that transports blood from hepatic veins into the inferior vena cava. In countries where BD is prevalent, including the Middle East and Far East, BCS awareness is important. In the present study, two cases of BCS are presented in two male Chinese patients with BD. The clinical characteristics, treatment and outcomes were recorded and compared with previous studies, and the features of BD-BCS were summarized...
March 2019: Experimental and Therapeutic Medicine
Amey D Sonavane, Deepak N Amarapurkar, Krantikumar R Rathod, Sundeep J Punamiya
Background: There has been significant improvement in understanding the etiology and management of Budd-Chiari Syndrome (BCS). Patients with chronic or acute-on-chronic BCS need radiological interventions in the form of angioplasty, hepatic vein/inferior vena cava stenting or Transjugular Intrahepatic Portosystemic Shunt (TIPS). Data regarding the long term follow up of patients undergoing TIPS is limited. We thus prospectively followed-up BCS patients who underwent TIPS at our center...
January 2019: Journal of Clinical and Experimental Hepatology
Elton Dajti, Federico Ravaioli, Antonio Colecchia, Giovanni Marasco, Amanda Vestito, Davide Festi
Aims: Budd-Chiari Syndrome (BCS) is a rare vascular disease of the liver caused by the obstruction of the hepatic venous outflow located from the small hepatic venules up to the entrance of the inferior vena cava (IVC) into the right atrium. Current prognostic indexes are suboptimal for an individual prognostic assessment and subsequent management of patients with BCS. Liver (LSM) and spleen (SSM) stiffness measurements are widely validated prognostic tools in hepatology, but the evidence in patients with BCS is limited...
2019: Canadian Journal of Gastroenterology & Hepatology
Jiaywei Tsauo, He Zhao, Xiaowu Zhang, Huaiyuan Ma, Mingshan Jiang, Ningna Weng, Xiao Li
PURPOSE: To evaluate effect of transjugular intrahepatic portosystemic shunt (TIPS) creation on pulmonary gas exchange in patients with hepatopulmonary syndrome (HPS). MATERIALS AND METHODS: All patients with cirrhosis or Budd-Chiari syndrome undergoing elective TIPS creation at a single institution between June 2014 and June 2015 were eligible for inclusion. Twenty-three patients with HPS (age 55.0 y ± 14.4; 11 men; Model for End-Stage Liver Disease score 10.2 ± 2...
February 2019: Journal of Vascular and Interventional Radiology: JVIR
Fu-Liang He, Chuan Li, Fu-Quan Liu, Xing-Shun Qi
BACKGROUND: Collagen proportionate area (CPA) is an important index for assessing the severity of liver fibrosis. Budd-Chiari syndrome can frequently progress to liver fibrosis and cirrhosis. CPA might play an important role in the pathological progress of Budd-Chiari syndrome. AIM: To explore the role of CPA in predicting the outcomes of patients with Budd-Chiari syndrome. METHODS: Nine patients with Budd-Chiari syndrome undergoing transjugular intrahepatic portosystemic shunt (TIPS) were included...
January 26, 2019: World Journal of Clinical Cases
Lei Fan, Huan Luo, Bing Liu, Xianen Fa, Tao Liu, Chao Ma
RATIONALE: Diabetic foot ulcer is a severe complication of diabetes, and most patients with diabetic foot ulcer require amputation. The incidence of Budd-Chiari syndrome is low; it is relatively rare. Diabetic foot ulcer combined with Budd-Chiari syndrome has not been reported so far. PATIENT CONCERNS: A 52-year-old man presented with uncontrolled high body temperature, continued expansion of the lower leg and foot ulcer with increasing malodor. DIAGNOSIS: The patient was diagnosed with Wagner grade 4 diabetic foot ulcer combined with Budd-Chiari syndrome...
January 2019: Medicine (Baltimore)
Pietro E Majno, Christian Toso, Thierry Berney
No abstract text is available yet for this article.
January 17, 2019: Annals of Surgery
Morgane van Wettere, Yvonne Purcell, Onorina Bruno, Audrey Payancé, Aurélie Plessier, Pierre-Emmanuel Rautou, Dominique Cazal-Hatem, Dominique Valla, Valérie Vilgrain, Maxime Ronot
BACKGROUND & AIM: To evaluate the diagnostic value of washout for the discrimination between benign and malignant lesions in patients with Budd-Chiari syndrome (BCS). METHODS: This IRB-approved retrospective study included all patients admitted to our institution with a diagnosis of BCS and focal lesions on MR imaging (MRI) from 2000 to 2016. MRI images were reviewed by two radiologists blinded to the nature of the lesions. Patient and lesion characteristics were recorded, with a focus on washout on portal venous and/or delayed phases...
January 14, 2019: Journal of Hepatology
Fang Yang, Ping-Chao Huang, Lei-Lei Yan, Ze-Dong Zhang, Yu-Fei Fu, Feng-Fei Xia
PURPOSE: To assess the safety and clinical effectiveness of catheter aspiration with recanalization in patients with Budd-Chiari syndrome (BCS) and inferior vena cava (IVC) thrombosis. MATERIALS AND METHODS: Between January 2010 and December 2017, 33 patients with BCS and IVC thrombosis were treated by catheter aspiration with IVC recanalization in our center. A 12 F angled-tip guiding catheter was used for the aspiration of thrombi in the IVC. Recanalization was conducted following thrombi aspiration...
January 8, 2019: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Damien Dousse, Eric Bloom, Bertrand Suc
BACKGROUND: Pancreaticoduodenectomy (PD)-induced morbidity, consisting mainly of the pancreatic fistula and its hemorrhagic and infectious consequences, is well described in the literature, in terms of its definition, risk factors, preventive measures, and standardized management of complications. However, some life-threatening complications remain atypical and undescribed. CASE SUMMARY: We report here the case of a 69-year-old patient with Budd-Chiari syndrome that occurred after arterial embolization of postpancreatectomy hemorrhage...
December 27, 2018: World Journal of Gastrointestinal Surgery
Akash Shukla, Abhinav Jain, Vinit Kahalekar, Sheetal Bendkhale, Nithya Gogtay, Urmila Thatte, Shobna Bhatia
INTRODUCTION: Anticoagulation is universally recommended in Budd-Chiari syndrome [BCS]. Vitamin K epoxide reductase complex 1 (VKORC1) and CYP2C9 are involved in the metabolism of warfarin. The present study was done to assess whether these mutations are associated with the risk of bleeding in patients with BCS receiving warfarin. PATIENTS AND METHODS: Patients diagnosed with BCS underwent genotyping for three single nucleotide polymorphisms [SNPs]-two for the CYP2C9 and one for the VKORC1 haplotype...
January 8, 2019: Hepatology International
Peng-Xu Ding, Xin-Wei Han, Chao Liu
Budd-Chiari syndrome (BCS) is a heterogeneous group of disorders characterized by hepatic venous outflow obstruction. Abernethy malformation is a congenital vascular malformation defined by diversion of portal blood away from the liver. Both conditions are rare vascular diseases. We report here the first case of a patient with combined type II Abernethy malformation and Budd-Chiari síndrome from China. The inferior vena cava obstruction was treated with percutaneous balloon angioplasty; close follow-up was elected for the Abernethy malformation...
December 13, 2018: Annals of Hepatology
Graeme Greenfield, Mary Frances McMullin
Background: Splanchnic Vein Thrombosis (SVT) is strongly associated with underlying JAK2 V617F positive myeloproliferative neoplasms (MPN). Methods: Patients attending the tertiary haematology service in Northern Ireland with SVT and underlying JAK2 V617F MPN were identified by consultant staff. A retrospective audit was undertaken to examine therapeutic interventions and relevant outcomes. Descriptive statistics were used for qualitative data whilst students t-test allowed comparison of quantitative data...
2018: Thrombosis Journal
De-Lei Cheng, Nan Zhu, Cheng-Li Li, Wei-Fu Lv, Wei-Wei Fang, Ya Liu, Chuan-Ting Li
Budd-Chiari syndrome (BCS) is a rare clinical syndrome caused by the obstruction of hepatic venous outflow. In theory, hepatic congestion and hypoxia induce pathological damage and changes in the liver. However, at present, laboratory evidence supporting this theory is lacking. The aim of the present study was to assess the expression and significance of the hypoxia-associated indicators malondialdehyde (MDA), superoxide dismutase (SOD) and endotoxin (ET) in the liver and serum of subjects with BCS. An animal model of BCS was established by partial ligation of the inferior vena cava (IVC) in rats...
December 2018: Experimental and Therapeutic Medicine
Peng Xu, Lulu Lyu, Muhammad Umair Sami, Xin Lu, Haitao Ge, Yutao Rong, Chunfeng Hu, Kai Xu
In recent years, the role of magnetic resonance angiography (MRA) in the diagnosis of Budd-Chiari Syndrome (BCS) has been the focus of various clinical studies. The purpose of the present study was to perform a meta-analysis of the diagnostic performance of MRA in patients with BCS by using digital subtraction angiography as a reference method. The search strategy for relevant research articles was based on the Cochrane Handbook for Systematic Reviews, and literature databases (including PubMed, Medline and China National Knowledge Infrastructure) and reference lists of retrieved studies published from 2000 to 2016 were searched...
December 2018: Experimental and Therapeutic Medicine
Yingying Li, Valerio De Stefano, Hongyu Li, Kexing Zheng, Zhaohui Bai, Xiaozhong Guo, Xingshun Qi
BACKGROUND AND AIMS: The global epidemiological data of Budd-Chiari syndrome (BCS) are scant. A systemic review and meta-analysis aimed to estimate the incidence and prevalence of BCS. METHODS: PubMed, EMBASE, and Cochrane Library databases were searched. The Newcastle-Ottawa Scale was used to assess the study quality. The pooled incidence and prevalence of BCS with 95% confidence intervals (CIs) were calculated by using a random-effect model. The heterogeneity was assessed by the Cochran's Q-test and I2 statistics...
December 7, 2018: Clinics and Research in Hepatology and Gastroenterology
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