keyword
https://read.qxmd.com/read/24049745/bilirubin-neurotoxicity-in-preterm-infants-risk-and-prevention
#21
REVIEW
Vinod K Bhutani, Ronald J Wong
Hemolytic conditions in preterm neonates, including Rhesus (Rh) disease, can lead to mortality and long-term impairments due to bilirubin neurotoxicity. Universal access to Rh immunoprophylaxis, coordinated perinatal-neonatal care, and effective phototherapy has virtually eliminated the risk of kernicterus in many countries. In the absence of jaundice due to isoimmunization and without access to phototherapy or exchange transfusion (in 1955), kernicterus was reported at 10.1%, 5.5%, and 1.2% in babies <30, 31-32, and 33-34 wks gestational age, respectively...
April 2013: Journal of Clinical Neonatology
https://read.qxmd.com/read/23743672/effect-of-position-of-infant-during-phototherapy-in-management-of-hyperbilirubinemia-in-late-preterm-and-term-neonates-a-randomized-controlled-trial
#22
RANDOMIZED CONTROLLED TRIAL
S Bhethanabhotla, A Thukral, M J Sankar, R Agarwal, V K Paul, A K Deorari
OBJECTIVE: To evaluate the effect of supine position when compared with periodic change of position during phototherapy in late preterm and term neonates (35 to 42 weeks) with hyperbilirubinemia on the duration of phototherapy. STUDY DESIGN: We randomly allocated enrolled neonates with hyperbilirubinemia to either no change in position (supine group (SG); n=54) or two-hourly change of position from supine to prone and vice versa (turning group (TG); n=46). All the infants received single surface phototherapy by two dedicated compact fluorescent light units...
October 2013: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/22808817/overview-of-neonatal-hyperbilirubinemia-at-nepal-medical-college-teaching-hospital
#23
JOURNAL ARTICLE
P Rijal, R P Bichha, B P Pandit, L Lama
This study was done to assess the prevalence of neonatal jaundice, underlying risk factors and efficacy of phototherapy, which would be of value in identifying and implementing strategies to prevent morbidity and mortality from this condition. A retrospective study was carried out in 86 neonates admitted to neonatal intensive care unit at Nepal Medical College Teaching Hospital, Attarkhel, Kathmandu from May, 2005 to April 2008. All of the newborns who developed hyperbilirubinemia and required phototherapy and/or exchange blood transfusion (EBT) were included in this study...
September 2011: Nepal Medical College Journal: NMCJ
https://read.qxmd.com/read/22696752/giant-placental-chorioangioma-a-rare-cause-of-fetal-hydrops
#24
JOURNAL ARTICLE
Andreia Barros, Ana Cristina Freitas, António Jorge Cabral, Maria Carmo Camacho, Edite Costa, Henrique Leitão, José Luis Nunes
Giant choriangiomas are rare placental tumours, associated with a high prevalence of pregnancy complications and a poor perinatal outcome. Neonatal consequences include severe microangiopathic haemolytic anaemia, thrombocytopaenia and hydrops. The associated high perinatal death rate (30-40%) has led to a number of prenatal therapeutic interventions with limited success in most cases. The authors present a case of non-immune fetal hydrops caused by a giant chorioangioma, diagnosed at 27 weeks of gestational age...
May 16, 2011: BMJ Case Reports
https://read.qxmd.com/read/22363075/urinary-tract-infection-and-indirect-hyperbilirubinemia-in-newborns
#25
JOURNAL ARTICLE
Chamdine Omar, Shadi Hamza, Abou Merhi Bassem, Rajab Mariam
BACKGROUND: Jaundice is a common problem during the neonatal period. About 60% of the full term and 80% of premature infants develop jaundice. It can be associated with serious illnesses such as Urinary tract infections. AIMS: The aim of this study is to evaluate the incidence and prevalence of urinary tract infection in newborns with indirect hyperbilirubinemia and to find a relationship with prolonged jaundice. PATIENTS AND METHODS: We retrospectively evaluated asymptomatic, jaundiced neonates for evidence of a urinary tract infection...
December 2011: North American Journal of Medical Sciences
https://read.qxmd.com/read/22355999/unfavourable-outcomes-associated-with-late-preterm-birth-observations-from-jordan
#26
JOURNAL ARTICLE
Osama Abu-Salah
OBJECTIVES: To determine the impact of late preterm birth on neonatal morbidity and neonatal unit admissions compared to full term babies in Amman, Jordan. METHODS: Data was extracted through retrospective file review from 2009 to 2010, on all singletons born at Queen Alia Hospital in Amman, Jordan. This cross sectional study noted gestational age at birth, weight, admission to the neonatal unit during birth hospitalization, respiratory distress, hypoglycaemia, evaluation for septicaemia, feeding difficulties and significant jaundice...
August 2011: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/21920055/neonatal-jaundice
#27
REVIEW
Paul Woodgate, Luke Anthony Jardine
INTRODUCTION: About 50% of term and 80% of preterm babies develop jaundice, which usually appears 2 to 4 days after birth, and resolves spontaneously after 1 to 2 weeks. Jaundice is caused by bilirubin deposition in the skin. Most jaundice in newborn infants is a result of increased red cell breakdown and decreased bilirubin excretion. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for unconjugated hyperbilirubinaemia in term and preterm infants? We searched Medline, Embase, The Cochrane Library, and other important databases up to February 2010 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review)...
September 15, 2011: Clinical Evidence
https://read.qxmd.com/read/21487057/effectiveness-of-antenatal-corticosteroids-in-reducing-respiratory-disorders-in-late-preterm-infants-randomised-clinical-trial
#28
RANDOMIZED CONTROLLED TRIAL
Ana Maria Feitosa Porto, Isabela Cristina Coutinho, Jailson Barros Correia, Melania Maria Ramos Amorim
OBJECTIVES: To determine the effectiveness of corticosteroids in reducing respiratory disorders in infants born at 34-36 weeks' gestation. Design Randomised triple blind clinical trial. Setting A large tertiary teaching hospital in northeast of Brazil. Participants Women at 34-36 weeks of pregnancy at risk of imminent premature delivery. Interventions Betamethasone 12 mg or placebo intramuscularly for two consecutive days. Main outcomes measures Primary outcome was the incidence of respiratory disorders (respiratory distress syndrome and transient tachypnoea of the newborn)...
April 12, 2011: BMJ: British Medical Journal
https://read.qxmd.com/read/21114525/national-guidelines-for-treatment-of-jaundice-in-the-newborn
#29
JOURNAL ARTICLE
D Bratlid, B Nakstad, T W R Hansen
UNLABELLED: Jaundice is the most common reason for instituting treatment in otherwise healthy as well as sick newborn infants. Herein, we describe the process employed in Norway to forge agreement on a set of treatment guidelines that are now used across the country. The Norwegian Pediatric Association was a key resource in this process, which involved contacts with all paediatric departments in Norway. We have also performed an international survey regarding the use of such national guidelines, showing that the majority of those queried confirm having national guidelines...
April 2011: Acta Paediatrica
https://read.qxmd.com/read/20724328/morbidity-and-discharge-timing-of-late-preterm-newborns
#30
JOURNAL ARTICLE
Laurie S Pulver, Jeffrey M Denney, Robert M Silver, Paul C Young
Late preterm newborns (LPNs), those with gestational ages (GAs) between 34 weeks and 36 weeks 6 days, account for 70% of preterm births. Because they have a mature appearance and are often cared for in a well baby nursery (WBN), parents may anticipate that the nursery course will be similar to that of a term infant and that their newborn will be discharged with his/her mother. How frequently their hospitalizations are prolonged beyond that of their mothers and the morbidities associated with prolonged hospitalization (PH) have not been well described...
November 2010: Clinical Pediatrics
https://read.qxmd.com/read/20669606/uptake-of-newly-introduced-universal-bcg-vaccination-in-newborns
#31
JOURNAL ARTICLE
O Braima, A Rigney, C A Ryan, C Murphy
Universal neonatal BCG vaccination was discontinued in Cork in 1972. Following an outbreak of TB in 2 creches in the HSE South, a universal BCG vaccination program was re-introduced in October 2008. The aim of this study was to determine the vaccination process (in-hospital and community) and the in-hospital uptake of the vaccine. Following informed parental consent, babies of birth weight > 2.5 Kg were eligible for in-hospital vaccination if they were not: febrile, jaundiced on phototherapy, on antibiotics and if not born to HIV- positive mothers...
June 2010: Irish Medical Journal
https://read.qxmd.com/read/20135268/transcutaneous-bilirubin-levels-in-healthy-term-and-late-preterm-indian-neonates
#32
JOURNAL ARTICLE
Satish Mishra, Deepak Chawla, Ramesh Agarwal, Ashok Kumar Deorari, Vinod Kumar Paul
OBJECTIVE: To provide normative data for transcutaneous bilirubin (TcB) measurements in healthy term and late-preterm Indian neonates during first 72 h of age using a multiwavelength reflectance transcutaneous bilimeter. METHODS: TcB measurements were performed in healthy neonates (gestation 35 wk), in a well-baby ward, using a multiwavelength transcutaneous bilimeter (BiliCheck, SpectRx Inc, Norcross, GA). Age-specific percentiles values for each 6-h epoch starting at 0 h of age were calculated and an age-specific TcB nomogram was developed using different percentile values...
January 2010: Indian Journal of Pediatrics
https://read.qxmd.com/read/19647501/-late-preterm-infants-a-population-at-underestimated-risk
#33
JOURNAL ARTICLE
X Demestre Guasch, F Raspall Torrent, S Martínez-Nadal, C Vila Cerén, M J Elizari Saco, P Sala Castellví
BACKGROUND AND OBJECTIVE: There has been a gradual rise in prematurity rates recent years, almost exclusively at the expense of the late preterm (34 to 36 weeks). This population, although with less risk than smaller preterm gestational age, has a morbidity rate significantly higher than term infants. However, there is some underestimation regarding developments in the short and long term. The aim of this study was to look at the incidence of prematurity in our institution and to analyze morbidity and mortality in late preterm compared with term infants SUBJECTS AND METHODS: We performed a retrospective review of newborns in our Hospital from January 1992 until December 31, 2008...
October 2009: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://read.qxmd.com/read/19399003/late-preterm-infants-severe-hyperbilirubinemia-and-postnatal-glucose-homeostasis
#34
REVIEW
D H Adamkin
The identification of late preterm infants as a high-risk group of infants has been an important public health breakthrough. These infants have suffered a relative 'silent morbidity and mortality' before the recognition that they have unique physiology and risks. These infants represent almost three-fourths of all premature births in the United States. Many of these infants, because of their birthweight and appearance, have been treated in Well Baby Nurseries and even discharged by 48 h of birth despite specific unidentified or unappreciated risks that have led to their readmission and possible severe morbidities or even death...
May 2009: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/19307221/visual-assessment-of-jaundice-in-term-and-late-preterm-infants
#35
JOURNAL ARTICLE
R Keren, K Tremont, X Luan, A Cnaan
OBJECTIVE: To determine the accuracy of predischarge visual assessment of jaundice for estimating bilirubin concentration and predicting risk of significant neonatal hyperbilirubinaemia. DESIGN: Prospective cohort study. SETTING: Well Baby Nursery at the Hospital of the University of Pennsylvania. PATIENTS: 522 term and late preterm newborns. INTERVENTIONS: Nurses used a 5-point scale to grade the maximum cephalocaudal extent of jaundice prior to discharge...
September 2009: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://read.qxmd.com/read/19242487/unbound-bilirubin-predicts-abnormal-automated-auditory-brainstem-response-in-a-diverse-newborn-population
#36
JOURNAL ARTICLE
C E Ahlfors, S B Amin, A E Parker
OBJECTIVE: The objective of this study was to determine if plasma unbound or 'free' bilirubin concentration (B(f)) measured during the first 30 days of life is associated with subsequent abnormal hearing screening testing by automated auditory brainstem response (AABR) in a diverse population of newborns. STUDY DESIGN: An observational study of newborns receiving AABR, plasma total bilirubin concentration (TBC) and B(f) measurements and without underlying conditions known to affect hearing was conducted...
April 2009: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/17451916/-transcutaneous-bilirubin-measurement-in-preterm-infants
#37
JOURNAL ARTICLE
I Mercanti, F Michel, L Thomachot, D-A Loundou, C Nicaise, R Vialet, J-N Di Marco, P Lagier, C Martin
UNLABELLED: Transcutaneous bilirubinometry is an effective screening tool for neonatal jaundice in full-term babies. But its accuracy is not shown yet in preterm infants. METHODOLOGY: We carried out a prospective study in a neonatal intensive care unit. The study included 47 preterm infants. From birth, a transcutaneous bilirubin measurement (BTc) using the BiliCheck was made on the forehead of each newborn every 8 h. Blood sampling for determination of total serum bilirubin (BS) was combined with BTc: 1) if value of BTc was higher than limits values for phototherapy; 2) on the second day of life and 3) 4 hours after cessation of phototherapy...
July 2007: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://read.qxmd.com/read/17096711/hypernatraemia-in-preterm-infants-born-at-less-than-27-weeks-gestation
#38
JOURNAL ARTICLE
Zuzanna Gawlowski, Narendra Aladangady, Pietro G Coen
AIMS: To study the incidence of hypernatraemia (plasma sodium >145 mmol/L), identify predisposing factors to and associated complications of hypernatraemia in preterm infants born less than 27 weeks gestation in the first 5 days of life. METHODS: Preterm infants less than 27 week gestation over an 18-month period were studied by retrospective analysis of patient records. Data were collected on gestation, birthweight, sex, antenatal steroid use, phototherapy, incubator humidity, time of transfer to incubator, plasma sodium, urea and creatinine...
December 2006: Journal of Paediatrics and Child Health
https://read.qxmd.com/read/16881988/a-systems-approach-for-neonatal-hyperbilirubinemia-in-term-and-near-term-newborns
#39
JOURNAL ARTICLE
Vinod K Bhutani, Lois H Johnson, Ann Schwoebel, Susan Gennaro
OBJECTIVE: To propose and implement a family-centered systems approach to manage newborn jaundice for safer outcomes. DESIGN: Observational study for known adverse outcomes. SETTING: Semiprivate urban birthing hospital. PATIENTS/PARTICIPANTS: 31,059 well babies discharged as healthy from a cohort of 41,961 live births (1990-2000). INTERVENTIONS: Incremental implementation of a systems approach that incorporated a hospital policy to (a) authorize nurses to obtain a bilirubin (total serum/transcutaneous) measurement for clinical jaundice, (b) universal predischarge total serum bilirubin (at routine metabolic screening), and (c) targeted follow-up, using the bilirubin nomogram (hour-specific, percentile-based total serum bilirubin/transcutaneous bilirubin)...
July 2006: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://read.qxmd.com/read/16223746/post-phototherapy-neonatal-bilirubin-rebound-a-potential-cause-of-significant-hyperbilirubinaemia
#40
JOURNAL ARTICLE
M Kaplan, E Kaplan, C Hammerman, N Algur, R Bromiker, M S Schimmel, A I Eidelman
AIM: To determine the incidence of post-phototherapy neonatal plasma total bilirubin (PTB) rebound. METHODS: A prospective clinical survey was performed on 226 term and near-term neonates treated with phototherapy in the well baby nursery of the Shaare Zedek Medical Center from January 2001 to September 2002. Neonates were tested for PTB 24 hours (between 12 and 36 hours) after discontinuation of phototherapy, with additional testing as clinically indicated. The main outcome measure, significant bilirubin rebound, was defined as a post-phototherapy PTB > or =256 micromol/l...
January 2006: Archives of Disease in Childhood
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