keyword
https://read.qxmd.com/read/38639537/location-selective-work-function-engineering-by-self-assembled-monolayers
#21
JOURNAL ARTICLE
Chaoran Zhang, Yangbiao Liu, Yian Tai, Andreas Terfort, Michael Zharnikov
Control over specific interfaces in devices represents a key challenge for modern organic electronics and photovoltaics. Such control is frequently gained by the use of self-assembled monolayers (SAMs), which, by selection of a proper anchoring group, are generally discriminative with respect to different materials but are not selective between different areas of the same material. In particular, selective tailoring of the work function may be useful for different functional devices in a circuit. Here we demonstrate an approach for solving this problem, opening a way to function-selective electrostatic engineering of chemically identical areas, such as source and drain electrodes in a specific type of organic transistor and, more importantly, the electrodes in different types of organic devices, such as p- and n-channel transistors, located on the same circuitry board...
April 19, 2024: Journal of Physical Chemistry Letters
https://read.qxmd.com/read/38638772/current-utility-of-transgastric-percutaneous-drainage-for-the-management-of-pancreatitis-related-retrogastric-walled-off-necrotic-collections-a-prospective-observational-study
#22
JOURNAL ARTICLE
Sarthak Agrawal, Asmita Arya, Avinash D Gautam, Rajanikant R Yadav, Ashish Singh, Deb Boruah, Samir Mohindra, Archana Gupta, Anshu Srivastava, Mohan Gurjar, Rajneesh K Singh, Rahul Rahul
Introduction Pancreatic fluid collection (PFC) is one of the most frequent complications associated with acute pancreatitis. The route of drainage is guided by the size and site of collection. The present study aims to assess the clinical and technical success of transgastric percutaneous drainage (PCD) for managing retrogastric walled-off pancreatic necrosis (WOPN). Materials and methods A total of 44 patients with acute pancreatitis diagnosed with WOPN who underwent transgastric PCD with ultrasound or CT guidance as part of standard clinical management were included in the study...
March 2024: Curēus
https://read.qxmd.com/read/38638760/a-retrospective-study-about-the-effectiveness-of-anastomosis-with-a-polyglycolic-acid-sheet-in-colorectal-cancer
#23
JOURNAL ARTICLE
Shoryu Takayama, Keisuke Tomoda, Ken Ishikawa, Masaki Sakamoto, Takeshi Hasegawa, Takehiko Eguchi, Satoru Takayama, Takahiro Mase
Introduction Anastomotic leakage is a serious complication in colon and rectal cancer surgeries, contributing to increased mortality rates and extended hospital stays. Despite various preventive measures, including intraoperative assessments and transanal drains, the incidence of anastomotic leakage remains a significant concern. This study investigates the potential efficacy of polyglycolic acid (PGA) sheets in reducing anastomotic leakage rates in gastrointestinal surgeries. Materials & methods A retrospective cohort study was conducted between January 2021 and January 2023 at Nagoya Tokushukai General Hospital, Ogaki Tokushukai Hospital, and Haibara General Hospital...
March 2024: Curēus
https://read.qxmd.com/read/38638489/clinical-trainee-performance-on-task-based-ar-vr-guided-surgical-simulation-is-correlated-with-their-3d-image-spatial-reasoning-scores
#24
JOURNAL ARTICLE
Roy Eagleson, Denis Kikinov, Liam Bilbie, Sandrine de Ribaupierre
This paper describes a methodology for the assessment of training simulator-based computer-assisted intervention skills on an AR/VR-guided procedure making use of CT axial slice views for a neurosurgical procedure: external ventricular drain (EVD) placement. The task requires that trainees scroll through a stack of axial slices and form a mental representation of the anatomical structures in order to subsequently target the ventricles to insert an EVD. The process of observing the 2D CT image slices in order to build a mental representation of the 3D anatomical structures is the skill being taught, along with the cognitive control of the subsequent targeting, by planned motor actions, of the EVD tip to the ventricular system to drain cerebrospinal fluid (CSF)...
2024: Healthcare Technology Letters
https://read.qxmd.com/read/38636830/health-care-associated-infections-after-surgical-treatment-of-ruptured-intracranial-aneurysms
#25
JOURNAL ARTICLE
Yu-Hua Huang, Tsung-Han Lee
BACKGROUND: Aneurysmal subarachnoid hemorrhage (SAH) is catastrophic, and microsurgery for ruptured intracranial aneurysms is one of the preventive modalities for rebleeding. However, patients remain at high risk of medical morbidities after surgery, one of the most important of which is health care-associated infections (HAIs). We analyzed the incidence and risk factors of HAIs, as well as their association with the outcomes after surgical treatment of ruptured aneurysms. METHODS: We retrospectively enrolled 607 patients with SAH who had undergone surgery for intracranial aneurysms...
April 16, 2024: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://read.qxmd.com/read/38636609/systematic-review-and-meta-analysis-of-cerebro-spinal-fluid-drain-related-mortality-and-morbidity-after-fenestrated-branched-endovascular-aortic-repair
#26
REVIEW
Nicola Leone, Mario D'Oria, Kevin Mani, Gustavo Oderich, Gianmarco Maleti, Luigi Am Bartolotti, Roberto Silingardi, Sandro Lepidi, Stefano Gennai
OBJECTIVE: This study aimed to investigate the incidence of cerebrospinal fluid drainage (CSFD)-related complications specifically in patients undergoing fenestrated and branched endovascular aortic repair (F/B-EVAR). This objective was chosen considering the limitations and uncertainties surrounding its efficacy in preventing spinal cord injury (SCI). METHODS: A systematic review following Cochrane Handbook and PRISMA guidelines was conducted (PROSPERO; #CRD42022359223)...
April 16, 2024: Journal of Vascular Surgery
https://read.qxmd.com/read/38635386/augmented-reality-based-contextual-guidance-through-surgical-tool-tracking-in-neurosurgery
#27
JOURNAL ARTICLE
Sangjun Eom, Seijung Kim, Joshua Jackson, David Sykes, Shervin Rahimpour, Maria Gorlatova
External ventricular drain (EVD) is a common, yet challenging neurosurgical procedure of placing a catheter into the brain ventricular system that requires prolonged training for surgeons to improve the catheter placement accuracy. In this paper, we introduce NeuroLens, an Augmented Reality (AR) system that provides neurosurgeons with guidance that aides them in completing an EVD catheter placement. NeuroLens builds on prior work in AR-assisted EVD to present a registered hologram of a patient's ventricles to the surgeons, and uniquely incorporates guidance on the EVD catheter's trajectory, angle of insertion, and distance to the target...
April 18, 2024: IEEE Transactions on Visualization and Computer Graphics
https://read.qxmd.com/read/38635170/spin-polarized-currents-induced-in-antiferromagnetic-polymer-multilayered-field-effect-transistors
#28
JOURNAL ARTICLE
Shih-Jye Sun, Miroslav Menŝík, Petr Toman
A theoretical construction of an antiferromagnetic polymer multilayered field-effect transistor with polymers stretched between the source and drain contacts was undertaken. The model employed a quantum approach to the on-chain spin-charge distribution, which was self-consistently coupled with the charge distribution controlled by the gate voltage. Contrary to standard field-effect transistors, we found that the current firstly increased superlinearly with the drain voltage, then it achieved the maximum for drain voltages notably lower than the gate voltage, and after that, it decreased with the drain voltage with no saturation...
April 18, 2024: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/38632502/risk-factors-for-relaparotomy-after-a-cesarean-delivery-a-case-control-study
#29
JOURNAL ARTICLE
Uri Amikam, Yael Botkovsky, Alyssa Hochberg, Aviad Cohen, Ishai Levin, Yariv Yogev, Liran Hiersch, Anat Lavie
BACKGROUND: Relaparotomy following a cesarean delivery (CD) is an infrequent complication, with inconsistency regarding risk factors and indications for its occurrence. We therefore aimed to determine risk factors and indications for a relaparotomy following a CD at a single large tertiary center. METHODS: A retrospective case-control single-center study (2013-2023). We identified all women who had a relaparotomy up to six weeks following a CD (study group). Maternal characteristics, obstetrical and surgical data were compared to a control group in a 1:2 ratio...
April 17, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38632219/robotic-biliary-stricturoplasty-and-roux-en-y-hepaticojejunostomy-after-hepatic-artery-infusion-pump-injury
#30
JOURNAL ARTICLE
Emanuel Shapera, Sharona Ross, Tara Pattilachan, Maria Christodoulou, Iswanto Sucandy
BACKGROUND: Hepatic artery infusion pump (HAIP) with floxuridine/dexamethasone and systemic chemotherapy is an established treatment regimen, which had been reported about converting 47% of patients with stage 4 colorectal liver metastasis from unresectable to resectable.1,2 To this effect, HAIP chemotherapy contributes to prolonged survival of many patients, which otherwise may not have other treatment options. Biliary sclerosis, however, is a known complication of the HAIP treatment, which occurs in approximately 5...
April 17, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38631904/outcomes-of-heparin-induced-thrombocytopenia-type-ii-in-aneurysmal-subarachnoid-hemorrhage-patients-a-us-nationwide-analysis
#31
JOURNAL ARTICLE
Galadu Subah, Sabrina Zeller, Nitesh Damodara, Michael Fortunato, Jenna Garrett, Shoaib Syed, Anaz Uddin, Issac Pak, Eric Feldstein, Stephan Mayer, Chirag D Gandhi, Fawaz Al-Mufti
BACKGROUND: Despite the widespread use of heparin during and following endovascular procedures in the management of aneurysmal subarachnoid hemorrhage (SAH) patients, limited research has explored the incidence and impact of heparin-induced thrombocytopenia (HIT) on SAH. METHODS: Descriptive statistics, multivariate regressions, and propensity score-matching were employed to compare clinical characteristics, comorbidities, interventions, complications, and outcomes of HIT in SAH patients identified within the US National Inpatient Sample database from 2010 to 2019...
April 17, 2024: Journal of Neurointerventional Surgery
https://read.qxmd.com/read/38631706/tumor-targeted-therapy-with-braf-inhibitor-recruits-activated-dendritic-cells-to-promote-tumor-immunity-in-melanoma
#32
JOURNAL ARTICLE
Florian Hornsteiner, Janine Vierthaler, Helen Strandt, Antonia Resag, Zhe Fu, Markus Ausserhofer, Christoph H Tripp, Sophie Dieckmann, Markus Kanduth, Kathryn Farrand, Sarah Bregar, Niloofar Nemati, Natascha Hermann-Kleiter, Athanasios Seretis, Sudhir Morla, David Mullins, Francesca Finotello, Zlatko Trajanoski, Guido Wollmann, Franca Ronchese, Marc Schmitz, Ian F Hermans, Patrizia Stoitzner
BACKGROUND: Tumor-targeted therapy causes impressive tumor regression, but the emergence of resistance limits long-term survival benefits in patients. Little information is available on the role of the myeloid cell network, especially dendritic cells (DC) during tumor-targeted therapy. METHODS: Here, we investigated therapy-mediated immunological alterations in the tumor microenvironment (TME) and tumor-draining lymph nodes (LN) in the D4M.3A preclinical melanoma mouse model (harboring the V-Raf murine sarcoma viral oncogene homolog B (BRAF)V600E mutation) by using high-dimensional multicolor flow cytometry in combination with multiplex immunohistochemistry...
April 17, 2024: Journal for Immunotherapy of Cancer
https://read.qxmd.com/read/38629806/ccr2-dependent-cx3cr1-colonic-macrophages-promote-enterococcus-faecalis-dissemination
#33
JOURNAL ARTICLE
Kevin C Jennings, Kaitlin E Johnson, Michael A Hayward, Christopher J Kristich, Nita H Salzman
Enterococci are common commensal bacteria that colonize the gastrointestinal tracts of most mammals, including humans. Importantly, these bacteria are one of the leading causes of nosocomial infections. This study examined the role of colonic macrophages in facilitating Enterococcus faecalis infections in mice. We determined that depletion of colonic phagocytes resulted in the reduction of E. faecalis dissemination to the gut-draining mesenteric lymph nodes. Furthermore, we established that trafficking of monocyte-derived CX3CR1-expressing macrophages contributed to E...
April 17, 2024: Infection and Immunity
https://read.qxmd.com/read/38629706/scheduled-follow-up-and-association-with-emergency-department-use-and-readmission-after-trauma
#34
JOURNAL ARTICLE
Sophia M Smith, Xuewei Zhao, Kelly Kenzik, Cara Michael, Kendall Jenkins, Sabrina E Sanchez
BACKGROUND: After traumatic injury, 13-14% of patients utilize the emergency department (ED) and 11% are readmitted within 30 days. Decreasing ED visits and readmission represents a target for quality improvement. This cohort study evaluates risk factors for ED visits and readmission after trauma, focusing on outpatient follow-up. STUDY DESIGN: We conducted a retrospective chart review of adult trauma admissions from 1/1/2018-12/31/2021. Our primary exposure was outpatient follow-up, our primary outcome was ED use, and our secondary outcome was readmission...
April 17, 2024: Journal of the American College of Surgeons
https://read.qxmd.com/read/38629449/j-misfet-hybrid-dual-gate-switching-device-for-multifunctional-optoelectronic-logic-gate-applications
#35
JOURNAL ARTICLE
Si Eun Yu, Han Joo Lee, Min-Gu Kim, Seongil Im, Young Tack Lee
High-performance and low operating voltage are becoming increasingly significant device parameters to meet the needs of future integrated circuit (IC) processors and ensure their energy-efficient use in upcoming mobile devices. In this study, we suggest a hybrid dual-gate switching device consisting of the vertically stacked junction and metal-insulator-semiconductor (MIS) gate structure, named J-MISFET. It shows excellent device performances of low operating voltage (<0.5 V), drain current ON/OFF ratio (∼4...
April 17, 2024: ACS Nano
https://read.qxmd.com/read/38629279/effect-of-clavipectoral-fascia-suturing-on-postmastectomy-seroma-formation
#36
RANDOMIZED CONTROLLED TRIAL
Mahmoud Mohammed, Hesham Hamza, Mohamed I Omar, Mohammed Hussein, Moaaz Tohamy, Basma Farouk, Khalid Rezk
&lt;b&gt;&lt;br&gt;Introduction:&lt;/b&gt; Post-mastectomy seroma formation is a challenging sequela which has a negative impact on patient recovery and quality of life.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Aim:&lt;/b&gt; We aim to publicize our technique of clavipectoral fascia re-closure and to assess its efficacy in reducing the incidence of seroma formation.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Methods:&lt;/b&gt; This is a prospective randomized controlled trial, conducted in South Cancer institute, Assiut University, Egypt...
October 13, 2023: Polski Przeglad Chirurgiczny
https://read.qxmd.com/read/38628676/dendritic-cell-based-immunotherapy-the-importance-of-dendritic-cell-migration
#37
REVIEW
Min-Seon Song, Ji-Hee Nam, Kyung-Eun Noh, Dae-Seog Lim
Dendritic cells (DCs) are specialized antigen-presenting cells that are crucial for maintaining self-tolerance, initiating immune responses against pathogens, and patrolling body compartments. Despite promising aspects, DC-based immunotherapy faces challenges that include limited availability, immune escape in tumors, immunosuppression in the tumor microenvironment, and the need for effective combination therapies. A further limitation in DC-based immunotherapy is the low population of migratory DC (around 5%-10%) that migrate to lymph nodes (LNs) through afferent lymphatics depending on the LN draining site...
2024: Journal of Immunology Research
https://read.qxmd.com/read/38626803/unveiling-the-submerged-secrets-bumblebee-queens-resilience-to-flooding
#38
JOURNAL ARTICLE
Sabrina Rondeau, Nigel E Raine
In a previous study, an experimental oversight led to the accumulation of water filling a container housing diapausing bumblebee queens. Surprisingly, after draining the water, queens were found to be alive. This observation raises a compelling question: can bumblebee queens endure periods of inundation while overwintering underground? To address this question, we conducted an experiment using 143 common eastern bumblebee ( Bombus impatiens ) queens placed in soil-filled tubes and subjected to artificially induced diapause in a refrigerated unit for 7 days...
April 2024: Biology Letters
https://read.qxmd.com/read/38626734/small-bowel-gastrointestinal-stromal-tumors-the-value-of-ct-enterography-in-assessing-pathological-aggressiveness
#39
JOURNAL ARTICLE
Huijuan Tu, Qiqi Chen, Jianchun Tu, Bingqing Dong, Feng Zhu, Shiyu Wang, Yanmiao Dai, Xu Chen
OBJECTIVE: This study aimed to characterize the computed tomography (CT) enterography features of the small bowel gastrointestinal stromal tumors (GIST) and to determine the association with pathological aggressiveness. METHODS: Computed tomography enterography images of 30 patients with the histologically confirmed small bowel GIST were retrospectively enrolled. Tumor size, location, border, growth pattern, enhancement pattern, necrosis, calcification, ulceration, internal air, nodal metastasis, liver metastasis, peritoneal metastasis, and draining vein were evaluated...
April 15, 2024: Journal of Computer Assisted Tomography
https://read.qxmd.com/read/38626091/facilitators-and-barriers-to-integrated-malaria-prevention-in-wakiso-district-uganda-a-photovoice-study
#40
JOURNAL ARTICLE
David Musoke, Grace B Lubega, Filimin Niyongabo, Suzan Nakalawa, Shannon McMorrow, Rhoda K Wanyenze, Moses R Kamya
Malaria continues to cause significant morbidity and mortality globally, particularly in sub-Saharan Africa. Appropriate combinations of non-chemical and chemical methods of malaria vector control in the context of integrated vector management have been recommended by the World Health Organization. The aim of the study was to explore facilitators and barriers to using integrated malaria prevention in Wakiso district, Uganda. This qualitative study employed photovoice among 20 community members in Kasanje Town Council, Wakiso District...
2024: PLOS Glob Public Health
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