Colin J Worby, Sushmita Sridhar, Sarah E Turbett, Margaret V Becker, Lucyna Kogut, Vanessa Sanchez, Ryan A Bronson, Sowmya R Rao, Elizabeth Oliver, Allison Taylor Walker, Maroya Spalding Walters, Paul Kelly, Daniel T Leung, Mark C Knouse, Stefan H F Hagmann, Jason B Harris, Edward T Ryan, Ashlee M Earl, Regina C LaRocque
BACKGROUND: Culture-based studies have shown that acquisition of extended-spectrum β-lactamase-producing Enterobacterales is common during international travel; however, little is known about the role of the gut microbiome before and during travel, nor about acquisition of other antimicrobial-resistant organisms. We aimed to identify (1) whether the gut microbiome provided colonisation resistance against antimicrobial-resistant organism acquisition, (2) the effect of travel and travel behaviours on the gut microbiome, and (3) the scale and global heterogeneity of antimicrobial-resistant organism acquisition...
September 13, 2023: The Lancet. Microbe