keyword
https://read.qxmd.com/read/38318256/examining-an-interaction-between-plasma-exchange-and-apixaban-resulting-in-an-acute-ischemic-stroke
#21
Katlyn Holt, Katelyn Dulgar, Justin P Reinert
Objective: Therapeutic drug monitoring is not routinely considered necessary in patients undergoing plasma exchange; however, it is possible for serum concentrations of select medications to be impacted by this procedure. Case: We describe a 50-year-old patient who presented to our facility with new onset aphasia and right-sided weakness. Despite presenting with a National Institute of Health Stroke Severity (NIHSS) score of 23, the patient did not receive fibrinolytic therapy due to his being anticoagulated with apixaban for atrial fibrillation...
February 2024: Journal of Pharmacy Technology: JPT: Official Publication of the Association of Pharmacy Technicians
https://read.qxmd.com/read/38304775/risk-factors-for-dysphagia-in-patients-with-acute-and-chronic-ischemic-stroke-a-retrospective-cohort-study
#22
JOURNAL ARTICLE
Lin Mao, Juehan Wang, Yubo Li, JinJin Zheng, Denghuang Fan, Shuang Wei, Xiaohong Wu, Xiaofeng Yang, Daming Wang
BACKGROUND: Dysphagia is a common and clinically significant complication of ischemic stroke. The prevalence and risk factors for dysphagia may vary at different stages following an ischemic stroke. METHODS: This study included patients with acute and chronic ischemic stroke who were treated at the Department of Rehabilitation, First Affiliated Hospital, Zhejiang University School of Medicine from 2019 to 2022. Various demographic, clinical, and laboratory parameters were collected, and statistical analyses were performed to investigate their association with dysphagia...
January 30, 2024: Heliyon
https://read.qxmd.com/read/38297193/theta-burst-stimulation-what-role-does-it-play-in-stroke-rehabilitation-a-systematic-review-of-the-existing-evidence
#23
JOURNAL ARTICLE
Tingting Jiang, Xiupan Wei, Mingzhu Wang, Jiang Xu, Nan Xia, Min Lu
Various post-stroke dysfunctions often result in poor long-term outcomes for stroke survivors, but the effect of conventional treatments is limited. In recent years, lots of studies have confirmed the effect of repetitive transcranial magnetic stimulation (rTMS) in stroke rehabilitation. As a new pattern of rTMS, theta burst stimulation (TBS) was proved recently to yield more pronounced and long-lasting after-effects than the conventional pattern at a shorter stimulation duration. To explore the role of TBS in stroke rehabilitation, this review summarizes the existing evidence from all the randomized controlled trials (RCTs) so far on the efficacy of TBS applied to different post-stroke dysfunctions, including cognitive impairment, visuospatial neglect, aphasia, dysphagia, spasticity, and motor dysfunction...
February 1, 2024: BMC Neurology
https://read.qxmd.com/read/38281579/white-matter-hyperintensities-as-a-predictor-of-aphasia-recovery
#24
JOURNAL ARTICLE
Joseph S Kang, Lisa D Bunker, Melissa D Stockbridge, Argye E Hillis
OBJECTIVE: To examine the relationship between baseline white matter hyperintensities (WMH) and change in naming, content production, and efficiency following treatment in subacute aphasia. We hypothesized that more severe baseline WMH would result in less improvement with treatment. DESIGN: Retrospective analysis of a cohort from a double-blind randomized controlled trial (RCT). SETTING: Outpatient clinical setting or participant home. PARTICIPANTS: We retrospectively reviewed imaging and behavioral data for 52 participants with subacute aphasia due to left-hemisphere ischemic stroke enrolled in the RCT...
January 26, 2024: Archives of Physical Medicine and Rehabilitation
https://read.qxmd.com/read/38275512/investigating-aphasia-recovery-demographic-and-clinical-factors
#25
JOURNAL ARTICLE
Georgios Papageorgiou, Dimitrios Kasselimis, Georgia Angelopoulou, Nikolaos Laskaris, Dimitrios Tsolakopoulos, Georgios Velonakis, Argyro Tountopoulou, Sophia Vassilopoulou, Constantin Potagas
Post-stroke language recovery remains one of the main unresolved topics in the field of aphasia. In recent years, there have been efforts to identify specific factors that could potentially lead to improved language recovery. However, the exact relationship between the recovery of particular language functions and possible predictors, such as demographic or lesion variables, is yet to be fully understood. In the present study, we attempted to investigate such relationships in 42 patients with aphasia after left hemisphere stroke, focusing on three language domains: auditory comprehension, naming and speech fluency...
December 21, 2023: Brain Sciences
https://read.qxmd.com/read/38265039/-coming-home-was-a-disaster-i-didn-t-know-what-was-going-to-happen-a-qualitative-study-of-survivors-and-family-members-experiences-of-navigating-care-post-stroke
#26
JOURNAL ARTICLE
Karen Fowler, Paula Mayock, Elaine Byrne, Kathleen Bennett, Eithne Sexton
PURPOSE: Understanding navigational barriers and facilitators has the potential to advance equitable stroke care delivery. The aim of this study was to explore, using a qualitative study, the experiences of stroke survivors and their families as they journey through the stroke care system, both before and during the COVID-19 pandemic. METHODS: In-depth semi-structured interviews were conducted with 18 stroke survivors and 12 family members during 2021 and 2022. Participants were recruited through voluntary organisations, social media, and stroke support groups...
January 24, 2024: Disability and Rehabilitation
https://read.qxmd.com/read/38257423/integrating-eeg-and-machine-learning-to-analyze-brain-changes-during-the-rehabilitation-of-broca-s-aphasia
#27
JOURNAL ARTICLE
Vanesa Močilnik, Veronika Rutar Gorišek, Jakob Sajovic, Janja Pretnar Oblak, Gorazd Drevenšek, Peter Rogelj
The fusion of electroencephalography (EEG) with machine learning is transforming rehabilitation. Our study introduces a neural network model proficient in distinguishing pre- and post-rehabilitation states in patients with Broca's aphasia, based on brain connectivity metrics derived from EEG recordings during verbal and spatial working memory tasks. The Granger causality (GC), phase-locking value (PLV), weighted phase-lag index (wPLI), mutual information (MI), and complex Pearson correlation coefficient (CPCC) across the delta, theta, and low- and high-gamma bands were used (excluding GC, which spanned the entire frequency spectrum)...
January 5, 2024: Sensors
https://read.qxmd.com/read/38248273/enhancing-speech-rehabilitation-in-a-young-adult-with-trisomy-21-integrating-transcranial-direct-current-stimulation-tdcs-with-rapid-syllable-transition-training-for-apraxia-of-speech
#28
Ester Miyuki Nakamura-Palacios, Aldren Thomazini Falçoni Júnior, Gabriela Lolli Tanese, Ana Carla Estellita Vogeley, Aravind Kumar Namasivayam
Apraxia of speech is a persistent speech motor disorder that affects speech intelligibility. Studies on speech motor disorders with transcranial Direct Current Stimulation (tDCS) have been mostly directed toward examining post-stroke aphasia. Only a few tDCS studies have focused on apraxia of speech or childhood apraxia of speech (CAS), and no study has investigated individuals with CAS and Trisomy 21 (T21, Down syndrome). This N-of-1 randomized trial examined the effects of tDCS combined with a motor learning task in developmental apraxia of speech co-existing with T21 (ReBEC RBR-5435x9)...
January 6, 2024: Brain Sciences
https://read.qxmd.com/read/38247371/incidence-and-influencing-factors-of-urinary-incontinence-in-stroke-patients-a-meta-analysis
#29
REVIEW
Shuyao Wang, Hua Kang, Qingyuan Wang, Dan Wang, Lizi Hu, Jiaojiao Kou, Zijiang Yang
BACKGROUND: The incidence of stroke in China ranks first in the world and is the leading cause of death and disability in adults. Urinary incontinence is an independent risk factor leading to poor prognosis of stroke. However, studies on the incidence of urinary incontinence in stroke patients and its influencing factors are different, fluctuate greatly, and there is no unified basis. OBJECTIVE: To quantitatively analyze the incidence of urinary incontinence in stroke patients and its related influencing factors, and further make public health strategic decisions to reduce the occurrence of adverse outcomes...
January 22, 2024: Neurourology and Urodynamics
https://read.qxmd.com/read/38244134/cerebellar-induced-aphasia-after-stroke-evidence-for-the-linguistic-cerebellum
#30
JOURNAL ARTICLE
Djaina Satoer, Peter J Koudstaal, Evy Visch-Brink, Ruben S van der Giessen
The cerebellum is traditionally known to subserve motor functions. However, for several decades, the concept of the "cerebellar cognitive affective syndrome" has evolved. Studies in healthy participants and patients have confirmed the cerebellar role in language. The exact involvement of the cerebellum regarding cerebellar aphasia remains uncertain. We included 43 cerebellar stroke patients who were tested at 3 months post-onset with the Boston Naming Test (BNT), the Token Test (TT), and the Diagnostic Instrument for Mild Aphasia (DIMA)...
January 20, 2024: Cerebellum
https://read.qxmd.com/read/38232746/the-intersectionality-of-climate-change-and-post-stroke-aphasia
#31
JOURNAL ARTICLE
Roby Greenwald, Jacqueline S Laures-Gore, Leticia M Nogueira
Persons with communication disabilities including persons with post-stroke aphasia (PWAs) possess a vulnerability to climate change as a result of their communication impairments. The disproportionate effects of climate change are likely to exacerbate preexisting inequities in social determinants of health. Communication disability intersecting with other characteristics subject to discrimination (e.g., race, age, sex, income) may lead to inequities in climate-related adaptive capacity. This article echoes earlier concerns related to climate change and further educates healthcare professionals about the impact of climate change on the global human population, with particular consideration of PWAs...
January 2024: Seminars in Speech and Language
https://read.qxmd.com/read/38228105/shared-neuroanatomical-substrates-for-co-occurring-swallowing-and-communication-impairments-after-acute-stroke
#32
Heather Flowers, David Mikulis, Frank Silver, Kannika Hour, Jason Steffener, Julien Poublanc, Elizabeth Rochon, Rosemary Martino
INTRODUCTION: Post-stroke dysphagia and communication impairments occur in two-thirds of acute stroke survivors. Identifying the shared neuroanatomical substrate for related impairments could facilitate the development of cross-system therapies. Our purpose was to elucidate discrete brain regions predictive of the combined presence of dysphagia alongside dysarthria and/or aphasia post-stroke. METHODS: We included 40 right (RHS) and 67 left hemisphere (LHS) patients from an acute ischemic stroke cohort with lesions demarcated on diffusion weighted imaging...
January 16, 2024: Cerebrovascular Diseases
https://read.qxmd.com/read/38227576/an-exploratory-study-of-longitudinal-trajectory-of-language-swallowing-and-cognition-post-endovascular-clot-retrieval
#33
JOURNAL ARTICLE
Pamela D'Netto, Emma Finch, Anna Rumbach, David A Copland
BACKGROUND: Endovascular clot retrieval (ECR) is known to reduce global disability at 3 months post stroke however limited research exists regarding the trajectory of specific clinical impairments including language, swallowing and cognitive deficits between onset and 3 months. AIMS: To assess language, swallowing, and cognitive performance following ECR and explore whether impairment severity is correlated with modified Thrombolysis in Cerebral Infarction score (mTICI), stroke severity or quality of life (QoL)...
January 16, 2024: International Journal of Language & Communication Disorders
https://read.qxmd.com/read/38224539/the-volume-and-the-distribution-of-premorbid-white-matter-hyperintensities-impact-on-post-stroke-aphasia
#34
JOURNAL ARTICLE
Veronika Vadinova, A J Sihvonen, F Wee, K L Garden, L Ziraldo, T Roxbury, K O'Brien, D A Copland, K L McMahon, S L E Brownsett
White matter hyperintensities (WMH) are a radiological manifestation of progressive white matter integrity loss. The total volume and distribution of WMH within the corpus callosum have been associated with pathological cognitive ageing processes but have not been considered in relation to post-stroke aphasia outcomes. We investigated the contribution of both the total volume of WMH, and the extent of WMH lesion load in the corpus callosum to the recovery of language after first-ever stroke. Behavioural and neuroimaging data from individuals (N = 37) with a left-hemisphere stroke were included at the early subacute stage of recovery...
January 2024: Human Brain Mapping
https://read.qxmd.com/read/38219713/connected-language-performance-in-neurotypical-and-persons-with-aphasia-use-of-the-brazilian-portuguese-story-retell-procedure-srp-bp
#35
JOURNAL ARTICLE
Karin Zazo Ortiz, Juliana Tognin, Juliana Silveira Ferreira de Medeiros, Tepanta R D Fossett, Malcolm R McNeil
INTRODUCTION: It is important to analyze the micro- and macrostructure of connected language production across languages in neurotypical and impaired speakers such as people with aphasia (PWA). However, the validity, reliability, sensitivity, or specificity of the available Brazilian-Portuguese connected language production batteries remains untested. OBJECTIVE: The purpose of this study was to provide a preliminary assessment of the translated Brazilian-Portuguese Story Retell Procedure (SRP-BP) in PWA and neurotypical control participants (NCP) and investigate whether the SRP can serve as a measure of overall communication impairment in PWA...
January 12, 2024: Folia Phoniatrica et Logopaedica
https://read.qxmd.com/read/38175228/-transcranial-direct-current-stimulation-to-enhance-training-effectiveness-in-chronic-poststroke-aphasia-a%C3%A2-challenge-for-recruiting-participants
#36
REVIEW
Nina Unger, Benjamin Stahl, Robert Darkow, Veronika Scholz, Isabel Weinmar, Johanna Schmidt, Caterina Breitenstein, Marcus Meinzer, Tanja Grewe, Agnes Flöel
INTRODUCTION/BACKGROUND: DC_TRAIN_APHASIA is an ongoing multicenter, randomized controlled trial, conducted since November 2019 under the lead of the University Medicine Greifswald (ClinicalTrials.gov Identifier: NCT03930121). The study seeks to determine whether adjuvant transcranial direct current stimulation (tDCS) can increase the effectiveness of a 3‑week treatment with intensive speech-language therapy in chronic post-stroke aphasia. MATERIAL AND METHOD: Until the end of 2024, a total of 130 patients are to be included in Germany...
January 4, 2024: Der Nervenarzt
https://read.qxmd.com/read/38163020/longitudinal-progression-of-white-matter-hyperintensity-severity-in-chronic-stroke-aphasia
#37
JOURNAL ARTICLE
Natalie Busby, Roger Newman-Norlund, Janina Wilmskoetter, Lisa Johnson, Chris Rorden, Makayla Gibson, Rebecca Roth, Sarah Wilson, Julius Fridriksson, Leonardo Bonilha
OBJECTIVE: To determine whether longitudinal progression of small vessel disease in chronic stroke survivors is associated with longitudinal worsening of chronic aphasia severity. DESIGN: A longitudinal retrospective study. Severity of white matter hyperintensities (WMHs) as a marker for small vessel disease was assessed on fluid-attenuated inversion recovery (FLAIR) scans using the Fazekas scale, with ratings for deep WMHs (DWMHs) and periventricular WMHs (PVHs)...
December 2023: Archives of rehabilitation research and clinical translation
https://read.qxmd.com/read/38162903/measurement-matters-for-assessing-the-role-of-chronically-altered-perfusion-in-post-stroke-aphasia
#38
JOURNAL ARTICLE
Cynthia K Thompson, Matthew Walenski
This scientific commentary refers to 'Cerebral perfusion in post-stroke aphasia and its relationship to residual language abilities', by Ivanova et al . (https://doi.org/10.1093/braincomms/fcad252).
2024: Brain communications
https://read.qxmd.com/read/38162898/cerebral-perfusion-in-post-stroke-aphasia-and-its-relationship-to-residual-language-abilities
#39
JOURNAL ARTICLE
Maria V Ivanova, Ioannis Pappas, Ben Inglis, Alexis L Pracar, Timothy J Herron, Juliana V Baldo, Andrew S Kayser, Mark D'Esposito, Nina F Dronkers
Stroke alters blood flow to the brain resulting in damaged tissue and cell death. Moreover, the disruption of cerebral blood flow (perfusion) can be observed in areas surrounding and distal to the lesion. These structurally preserved but suboptimally perfused regions may also affect recovery. Thus, to better understand aphasia recovery, the relationship between cerebral perfusion and language needs to be systematically examined. In the current study, we aimed to evaluate (i) how stroke affects perfusion outside of lesioned areas in chronic aphasia and (ii) how perfusion in specific cortical areas and perilesional tissue relates to language outcomes in aphasia...
2024: Brain communications
https://read.qxmd.com/read/38160205/network-based-statistics-distinguish-anomic-and-broca-s-aphasia
#40
JOURNAL ARTICLE
Nicholas Riccardi, Xingpei Zhao, Dirk-Bart den Ouden, Julius Fridriksson, Rutvik H Desai, Yuan Wang
INTRODUCTION: Aphasia is a speech-language impairment commonly caused by damage to the left hemisphere. The neural mechanisms that underpin different types of aphasia and their symptoms are still not fully understood. This study aims to identify differences in resting-state functional connectivity between anomic and Broca's aphasia measured through resting-state functional magnetic resonance imaging (rs-fMRI). METHODS: We used the network-based statistic (NBS) method, as well as voxel- and connectome-based lesion symptom mapping (V-, CLSM), to identify distinct neural correlates of the anomic and Broca's groups...
December 30, 2023: Brain Structure & Function
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