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post stroke aphasia

Rene L Utianski, Joseph R Duffy, Heather M Clark, Mary M Machulda, Dennis W Dickson, Jennifer L Whitwell, Keith A Josephs
Aphasia typically is associated with comparable difficulties in written and spoken modalities of language expression and comprehension. In contrast, auditory verbal agnosia is the disproportionate difficulty comprehending spoken compared to written language, also typically greater than difficulties with spoken and written language expression, in the absence of a primary sensory deficit. The terms pure word deafness and auditory verbal agnosia are often used synonymously. However, the broader term of auditory agnosia more accurately reflects difficulty processing both speech and non-speech sounds whereas individuals with auditory verbal agnosia (pure word deafness) have preserved processing of environmental sounds...
February 21, 2019: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Denise Y Harvey, Joely A Mass, Priyanka P Shah-Basak, Rachel Wurzman, Olufunsho Faseyitan, Daniela L Sacchetti, Laura DeLoretta, Roy H Hamilton
BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) has been used experimentally to facilitate naming abilities in individuals with chronic post-stroke aphasia. However, little is known about how rTMS confers clinical improvement, hampering its therapeutic value. The present study investigated the characteristics of naming failure that improve following administration of continuous theta burst stimulation (cTBS)-an inhibitory form of rTMS-to the right pars triangularis (rPTr) in persons with chronic aphasia...
March 11, 2019: Brain and Language
Jason Godlove, Veera Anantha, Mahendra Advani, Carrie Des Roches, Swathi Kiran
Background: Computer-based therapies can provide an affordable and practical alternative by providing frequent intervention for stroke survivors with chronic aphasia by allowing the opportunity for home exercise practice, however more evidence is needed. The goal of this retrospective analysis was to compare the time course of therapy engagement when therapy was targeted in the clinic or at home by post-stroke individuals. We examined if home users of the therapy were compliant in therapy and if this documented practice time was associated with improved outcomes similar to clinic patients who practiced under the guidance of a clinician...
2019: Frontiers in Neurology
L A Lopez-Romero, D M Riano-Carreno, M Y Pachon-Poveda, J A Mendoza-Sanchez, Y K Leon-Vargas, A Moreno-Pabon, R Trillos-Leal, R G Garcia-Gomez, L C Rueda-Guzman, F Silva
INTRODUCTION: Non-fluent aphasia is a frequent complication in post-ischemic stroke patients, with repetitive transcranial magnetic stimulation (rTMS) being one of the possible treatment alternatives. AIM: To assess the efficacy and safety of rTMS in patients with non-fluent after-ischemic stroke aphasia. PATIENTS AND METHODS: Double blind, randomized controlled clinical trial in post-stroke patients who were assigned to receive 10 sessions (one daily) of active treatment or placebo of rTMS, without the addition of language therapy...
March 16, 2019: Revista de Neurologia
Nazbanou Nozari
According to most models of language production, to name a picture one must first map semantic features onto lexical items. Even if both sets of representations are intact, problems in mapping semantic to lexical representations can impair production. Individuals with this problem, sometimes referred to as "access deficit", often demonstrate evidence of preserved semantic knowledge (e.g., good comprehension), increased rate of lexical (usually semantic) errors in production, and inconsistent accuracy on naming the same picture on different occasions...
March 8, 2019: Cognitive Neuropsychology
Mira Goral, Monica Norvik, Bård Uri Jensen
Mixing languages within a sentence or a conversation is a common practice among many speakers of multiple languages. Language mixing found in multilingual speakers with aphasia has been suggested to reflect deficits associated with the brain lesion. In this paper, we examine language mixing behaviour in multilingual people with aphasia to test the hypothesis that the use of language mixing reflects a communicative strategy. We analysed connected language production elicited from 11 individuals with aphasia...
March 5, 2019: Clinical Linguistics & Phonetics
Sarah Benghanem, Charlotte Rosso, Céline Arbizu, Eric Moulton, Didier Dormont, Anne Leger, Christine Pires, Yves Samson
OBJECTIVES: The outcome of aphasia at 3 months is variable in patients with moderate/severe stroke. The aim was to predict 3-month aphasia outcome using prediction models including initial severity in addition to the interaction between lesion size and location at the acute phase. METHODS: Patients with post-stroke aphasia (assessed by the Aphasia Rapid Test at day 7-ART D7) and MRI performed at day 1 were enrolled (n = 73). Good outcome at 3-months was defined by an Aphasia Handicap Score of 0-2...
February 28, 2019: Journal of Neurology
Marina Laganaro, Caroline Bonnans, Raphael Fargier
Although speakers can go on producing utterances while doing concurrent tasks, language planning is affected in conditions of divided attention. It is however unclear whether a concurrent task impacts only lexical selection, or if post-lexical processing is also impacted. To elucidate this question, we reasoned that if an encoding process is under attentional control, this should be even more the case when the planning process is disrupted due to brain damage: increased error rates in left-hemisphere damaged participants under dual-task conditions should therefore shed light on which encoding processes need attentional resources...
February 27, 2019: Cognitive Neuropsychology
Erin L Foley, Marjorie L Nicholas, Carolyn M Baum, Lisa Tabor Connor
Objectives: For rehabilitation professionals to adequately address meaningful participation in social activities with their patients after a stroke, there must be a better understanding of neurobehavior, that is, how neurological impairment and its sequelae and environmental factors support or limit social participation. The current study examines how stroke severity (NIH Stroke Scale), its impact on perceived mobility (Stroke Impact Scale mobility domain), and the environment (MOS Social Support-Positive Social Interactions scale and Measure of Stroke Environment receptivity and built environment domains) influence social participation (Activity Card Sort: ACS)...
2019: Behavioural Neurology
Jasvinder K Sekhon, Jennifer Oates, Ian Kneebone, Miranda Rose
BACKGROUND: Speech-language therapists use counselling to address the psychological well-being of people affected by post-stroke aphasia. Speech-language therapists report low counselling knowledge, skill and confidence for working in post-stroke aphasia which may be related to a lack of counselling training specific to the needs of this client group. AIMS: To identify current training in counselling for speech-language therapists to address psychological well-being in people affected by post-stroke aphasia...
February 13, 2019: International Journal of Language & Communication Disorders
Adam Gerstenecker, Ronald M Lazar
OBJECTIVE: To review the research literature pertaining to post-stroke language recovery, and to discuss neurocognitive assessment in patients in the context of aphasia, time course of language recovery, factors associated with language recovery, and therapeutic techniques designed to facilitate language recovery. METHOD: Articles were identified through PubMed, MEDLINE, PsychINFO, and Google Scholar searches. Examples of utilized keywords include "post-stroke aphasia," "post-stroke language recovery," "post-stroke neurocognitive assessment," and "neuropsychology and aphasia...
January 30, 2019: Clinical Neuropsychologist
Katerina Hilari, Nicholas Behn, Jane Marshall, Alan Simpson, Shirley Thomas, Sarah Northcott, Chris Flood, Sally McVicker, Mireia Jofre-Bonet, Becky Moss, Kirsty James, Kimberley Goldsmith
Background: Despite the high prevalence of mood problems after stroke, evidence on effective interventions particularly for those with aphasia is limited. There is a pressing need to systematically evaluate interventions aiming to improve wellbeing for people with stroke and aphasia. This study aims to evaluate the feasibility of a peer-befriending intervention. Methods/design: SUPERB is a single blind, parallel group feasibility trial of peer befriending for people with aphasia post-stroke and low levels of psychological distress...
2019: Pilot and Feasibility Studies
Joshua Troche, Arielle Willis, Janet Whiteside
Background: Dementia can lead to difficulties in communication between caregivers and patients. Teaching conversational strategies has been effective for a wide array of clients with acquired neurologic disorders and their caregivers. Research indicates positive results for Supported Conversation for adults with Aphasia (SCA) secondary to stroke. Applying this method to work with caregivers of individuals with dementia could prove to be a valid intervention tool. This investigation examined the applicability of SCA with individuals with dementia and their familial caregivers...
2019: Pilot and Feasibility Studies
Anastasios Georgiou, Nikos Konstantinou, Ioannis Phinikettos, Maria Kambanaros
The present study reports the findings of a 10-day neuronavigated continuous theta burst stimulation (cTBS) over the right pars triangularis for two individuals with chronic aphasia after a single left hemispheric stroke. Baseline language and quality of life measures were collected prior to the treatment study, post-treatment and at 3-month follow up. Therapy was tolerated well by both participants and no side effects were noticed during and after treatment. Results from one individual showed potential for positive change in performance in comprehension and expressive language both post-treatment and at the follow-up stage...
January 24, 2019: Clinical Linguistics & Phonetics
Imama Naqvi, Emi Hitomi, Richard Leigh
OBJECTIVE: To report a patient in whom an acute ischemic stroke precipitated chronic blood-brain barrier (BBB) disruption and expansion of vascular white matter hyperintensities (WMH) into regions of normal appearing white matter (NAWM) during the following year. BACKGROUND: WMH are a common finding in patients with vascular risk factors such as a history of stroke. The pathophysiology of WMH is not fully understood; however, there is growing evidence to suggest that the development of WMH may be preceded by the BBB disruption in the NAWM...
January 21, 2019: Brain Sciences
Elisa Biou, Hélène Cassoudesalle, Mélanie Cogne, Igor Sibon, Isabelle De Gabory, Patrick Dehail, Jerome Aupy, Bertrand Glize
BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive tool that induces neuromodulation in the brain. Several studies have shown the effectiveness of tDCS in improving language recovery in post-stroke aphasia. However, this innovative technique is not currently used in routine speech and language therapy (SLT) practice. OBJECTIVE: This systematic review aimed to summarise the role of tDCS in aphasia rehabilitation. METHODS: We searched MEDLINE via PubMed and Scopus on October 5, 2018 for English articles published from 1996 to 2018...
January 17, 2019: Annals of Physical and Rehabilitation Medicine
Jason Geller, Melissa Thye, Daniel Mirman
Despite the critical importance of close replications in strengthening and advancing scientific knowledge, there are inherent challenges to conducting replications of lesion-based studies. In the present study, we conducted a close conceptual replication of a study (i.e., Hope et al., 2016) that found that fluency and naming scores in post-stoke aphasia were more strongly associated with a binary measure of structural white matter integrity (tract disconnection) than a graded measure (lesion load). Using a different sample of stroke patients (N = 128) and four language deficit measures (aphasia severity, picture naming, and composite scores for speech production and semantic cognition), we examined tract disconnection and lesion load in three white matter tracts that have been implicated in language processing: arcuate fasciculus, uncinate fasciculus, and inferior fronto-occipital fasciculus...
January 14, 2019: NeuroImage
Natalie Gilmore, Erin L Meier, Jeffrey P Johnson, Swathi Kiran
OBJECTIVE: To determine if pre-treatment non-linguistic cognition predicted language treatment outcomes and if so, which specific non-linguistic cognitive subskills predicted naming therapy outcomes. DESIGN: Retrospective. SETTING: Research clinic. PARTICIPANTS: Study 1 included data from 67 persons with aphasia who underwent language treatment and a pre-treatment cognitive-linguistic assessment battery. Study 2 included data from 27 Study 1 participants who completed additional pre-treatment non-linguistic cognitive assessments...
January 9, 2019: Archives of Physical Medicine and Rehabilitation
Andrea Dreßing, Cornelius Weiller, Klaus Foerster, Harald Dreßing
Aphasia is a frequent cognitive disorder after stroke. Despite a high prevalence, there is comparatively little medical literature or high court jurisdiction concerning the question if aphasia impairs patients in their legal capacity.Imaging studies allow a detailed understanding of the underlying pathology of aphasia, the resulting clinical pictures and potential mechanisms of recovery. Based on functional-anatomical models of language and associated concepts of inner speech, the impact of language disorders on legal capacity is evaluated...
December 2018: Fortschritte der Neurologie-Psychiatrie
V M Shklovskij, V V Alferova, E G Ivanova, L A Mayorova, A G Petrushevsky, G V Ivanov, S V Kuptsova, E A Kondrateva, A B Guekht
AIM: To analyze clinical and fMRI indicators related with the therapeutic effectiveness of complex restorative treatment including intensive speech therapy in various clinical forms and severity of the aphasia syndrome. MATERIAL AND METHODS: The study included 40 right-handed patients with aphasia syndrome after the first hemispheric ischemic stroke. Patients were studied 3 month after disease onset. Patients were examined before and after rehabilitation treatment (4...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
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