Harry Ramcharran, Greg Wetmore, Scott Cooper, Jacob Herrmann, Andrea F Cruz, David W Kaczka, Joshua Satalin, Sarah Blair, Penny L Andrews, Nader M Habashi, Gary F Nieman, Michaela Kollisch-Singule
BACKGROUND: Lung volume measurements are important for monitoring functional aeration and recruitment, and may help guide adjustments in ventilator settings. The expiratory phase of APRV may provide physiologic information about lung volume based on the expiratory flow-time slope, angle, and time to approach a no-flow state (TExp ). We hypothesized that expiratory flow rate would correlate with estimated lung volume (ELV), as measured using a modified nitrogen washout/washin technique in a large animal lung injury model...
February 26, 2024: Respiratory Care