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JOURNAL ARTICLE
Ophir Freund, Levi Elhadad, Boaz Tiran, Ariel Melloul, Eyal Kleinhendler, Tal Moshe Perluk, Evgeni Gershman, Avraham Unterman, Avishay Elis, Amir Bar-Shai
BACKGROUND: Implementing standard of care therapy for chronic obstructive pulmonary disease (COPD) has barriers. Hospitalization with an acute exacerbation of COPD (AECOPD) is a major adverse event that could also be an opportunity to improve patients' long-term care. OBJECTIVES: To evaluate which in-hospital interventions during AECOPD are associated with improved 30-day care. METHODS: This was a prospective study that included patients from 10 medical centers across Israel, hospitalized with AECOPD between 2017 and 2019...
May 14, 2024: Heart & Lung: the Journal of Critical Care
#62
JOURNAL ARTICLE
Carolina Silva Figueiredo, Ana Margarida Neto da Rocha, Liane Maria Correia Rodrigues da Costa Nogueira Silva, Maria do Sameiro Pinto César de Faria, Teresa Maria Tavares Vieira da Costa Tavares, Maria da Conceição Oliveira Costa Mota
INTRODUCTION: Acute kidney injury (AKI) is an abrupt deterioration of kidney function. The incidence of pediatric AKI is increasing worldwide, both in critically and non-critically ill settings. We aimed to characterize the presentation, etiology, evolution, and outcome of AKI in pediatric patients admitted to a tertiary care center. METHODS: We performed a retrospective observational single-center study of patients aged 29 days to 17 years and 365 days admitted to our Pediatric Nephrology Unit from January 2012 to December 2021, with the diagnosis of AKI...
2024: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
#63
JOURNAL ARTICLE
Shigeto Horiuchi, Makoto Hibino, Shunichi Tobe, Kazunari Maeda, Riko Kamada, Shigehiro Watanabe, Tetsuri Kondo
No abstract text is available yet for this article.
May 15, 2024: American Journal of Respiratory and Critical Care Medicine
#64
REVIEW
Antoine Lafarge, Dara Chean, Livia Whiting, Raphaël Clere-Jehl
Hematological malignancies may require rapid-onset treatment because of their short doubling time, notably observed in acute leukemias and specific high-grade lymphomas. Furthermore, in targeted onco-hematological scenarios, chemotherapy is deemed necessary as an emergency measure when facing short-term, life-threatening complications associated with highly chemosensitive hematological malignancies. The risks inherent in the disease itself, or in the initiation of treatment, may then require admission to the intensive care unit (ICU) to optimize monitoring and initial management protocols...
May 15, 2024: Intensive Care Medicine
#65
JOURNAL ARTICLE
Rithvik Ramesh, John K Yue, Geoffrey T Manley, Phiroz E Tarapore, Anthony M DiGiorgio
BACKGROUND AND OBJECTIVES: Despite profound medico-socio-legal consequences of traumatic brain injury (TBI) from intimate partner violence and domestic violence (IPV/DV), the incidence and acute outcomes of concurrent IPV/DV-TBI are not well understood. We examined US IPV/DV patients with/without TBI (IPV/DV-TBI; non-TBI) using the National Trauma Data Bank. We hypothesized IPV/DV-TBI would be associated with elevated morbidity. METHODS: National Trauma Data Bank Trauma Quality Programs Participant Use Files years 2018 to 2021 were queried for patients aged ≥18 years with IPV/DV using International Classification of Diseases, Tenth Revision external cause codes...
May 15, 2024: Neurosurgery
#66
JOURNAL ARTICLE
Steven P Cass, Dan V Nicolau, Jonathan R Baker, Christine Mwasuku, Sanjay Ramakrishnan, Mahdi Mahdi, Peter J Barnes, Louise E Donnelly, Rocio T Martinez-Nunez, Richard E K Russell, Mona Bafadhel
INTRODUCTION: Understanding the interplay of immune mediators in relation to clinical outcomes during acute infection has the potential to highlight immune networks critical to symptom recovery. The objective of the present study was to elucidate the immune networks critical to early symptom resolution following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. METHODS: In a community-based randomised clinical trial comparing inhaled budesonide against usual care in 139 participants with early onset SARS-CoV-2 (the STOIC study; clinicaltrials...
May 2024: ERJ Open Research
#67
REVIEW
Amy A Mrazek, Preston Simpson, Jong O Lee
Nutrition and modulation of the hypermetabolic response to acute burns are reviewed in this article. Methods to determine caloric requirements are evaluated, including indirect calorimetry and predictive equations. Individual nutritional components of carbohydrates, fat, protein, vitamins, and trace elements are discussed specifically in relation to acute burn care. Selection of formula and route of administration are outlined, with an enteral high-carbohydrate, low-fat diet being preferable. Awareness and recognition of the signs and symptoms of malnutrition is critical in the management of variable caloric needs throughout hospitalization...
May 2024: Seminars in Plastic Surgery
#68
REVIEW
Nicola M A Rea, Lis Neubeck, Kalliopi Kydonaki, Sheona McHale
BACKGROUND: Intensive care units deliver care to a heterogeneous group of patients with pre-existing co-morbid disease. Focus has shifted to improving health related quality of life with more patients surviving beyond hospital discharge. Randomised controlled trials evaluating follow-up interventions, to improve physical recovery, have not demonstrated a health-related quality of life benefit. Qualitative research may provide the context to understand the experiences of intensive care survivors during follow-up care addressing physical limitations...
December 2023: International journal of nursing studies advances
#69
REVIEW
Laura L Walton, Elsie Duff, Rakesh C Arora, Diana E McMillan
BACKGROUND: Post-operative pain is a major factor in surgical recovery. There is evidence that pain remains undermanaged. Complications related to the undermanagement of acute pain can increase length of stay and contribute to readmission and the development of chronic pain. It is well acknowledged that pain assessment is critical to pain management and that self-report of pain is the gold standard. As a result, patients play a central role in their own pain management. A preliminary review of the literature failed to provide a clear or consistent description of this key patient role...
December 2023: International journal of nursing studies advances
#70
JOURNAL ARTICLE
Ian Ergui, Nayrana Griffith, Joshua Salama, Bertrand Ebner, Michael Dangl, Louis Vincent, Victor Razuk, George Marzouka, Rosario Colombo
Patients with neurodevelopmental disorders (NDDs) encounter significant barriers to receiving quality health care, particularly for acute conditions such as non-ST segment elevation myocardial infarction (NSTEMI). This study addresses the critical gap in knowledge regarding in-hospital outcomes and the use of invasive therapies in this demographic. By analyzing data from the National Inpatient Sample database from 2011 to 2020 using the International Classification of Diseases, Ninth Edition (ICD-9) and Tenth Edition (ICD-10) codes, we identified patients with NSTEMI, both with and without NDDs, and compared baseline characteristics, in-hospital outcomes, and the application of invasive treatments...
May 2024: Curēus
#71
Zoe Calulo Rivera, Felipe González-Seguel, Arimitsu Horikawa-Strakovsky, Catherine Granger, Aarti Sarwal, Sanjay Dhar, George Ntoumenopoulos, Jin Chen, V K Cody Bumgardner, Selina M Parry, Kirby P Mayer, Yuan Wen
INTRODUCTION/AIMS: Muscle ultrasound has high utility in clinical practice and research; however, the main challenges are the training and time required for manual analysis to achieve objective quantification of morphometry. This study aimed to develop and validate a software tool powered by artificial intelligence (AI) by measuring its consistency and predictability of expert manual analysis quantifying lower limb muscle ultrasound images across healthy, acute, and chronic illness subjects...
April 30, 2024: medRxiv
#72
JOURNAL ARTICLE
Pamela B Andreatta, John Christopher Graybill, Matthew J Bradley, Kirby R Gross, Eric A Elster, Mark W Bowyer
BACKGROUND: The clinical demands of mass casualty events strain even the most well-equipped trauma centers and are especially challenging in resource-limited rural, remote, or austere environments. Gynecologists and urologists care for patients with pelvic and abdominal injuries, but the extent to which they are able to serve as "force multipliers" for trauma care is unclear. This study examined the abilities of urologists and gynecologists to perform 32 trauma procedures after mentored training by expert trauma educators to inform the potential for these specialists to independently care for trauma patients...
May 15, 2024: Journal of Trauma and Acute Care Surgery
#73
JOURNAL ARTICLE
Patrick L Johnson, Shukri H A Dualeh, Ayobami Ward, Raymond A Jean, Staci Aubry, Alistair Chapman, William Curtiss, Jacob Joseph, John W Scott, Mark R Hemmila
BACKGROUND: Trauma patients are at increased risk for venous thromboembolism events (VTE). The decision of when to initiate VTE chemoprophylaxis (VTEP) and with what agent remains controversial in patients with severe traumatic brain injury (TBI). METHODS: This comparative effectiveness study evaluated the impact of timing and agent for VTEP on outcomes for patients with severe TBI (AIS Head = 3,4, or 5). Data was collected at 35 Level 1 and 2 trauma centers from January 1, 2017 to June 1, 2022...
May 15, 2024: Journal of Trauma and Acute Care Surgery
#74
JOURNAL ARTICLE
Rachel L Choron, Michael Rallo, Charoo Piplani, Sara Youssef, Amanda L Teichman, Christopher G Bargoud, Jason D Sciarretta, Randi N Smith, Dustin S Hanos, Iman N Afif, Jessica H Beard, Navpreet K Dhillon, Ashling Zhang, Mira Ghneim, Rebekah J Devasahayam, Oliver L Gunter, Alison A Smith, Brandi L Sun, Chloe Cao, Jessica K Reynolds, Lauren A Hilt, Daniel Holena, Grace Chang, Meghan Jonikas, Karla Echeverria, Nathaniel Fung, Aaron Anderson, Ryan P Dumas, Caitlin A Fitzgerald, Jeremy Levin, Christine Trankiem, JaeHee Jane Yoon, Jacqueline Blank, Joshua Hazelton, Christopher J McLaughlin, Rami Al-Aref, Jordan M Kirsch, Daniel S Howard, Dane R Scantling, Kate Dellonte, Michael Vella, Brent Hopkins, Chloe Shell, Pascal O Udekwu, Evan G Wong, Bellal A Joseph, Howard Lieberman, Walter Ramsey, Collin Stewart, Claudia Alvarez, John D Berne, Jeffry Nahmias, Ivan Puente, J Pat Patton, Ilya Rakitin, Lindsey L Perea, Odessa R Pulido, Hashim Ahmed, Jane Keating, Lisa Kodadek, Jason Wade, Reynold Henry, Martin Schreiber, Andrew Benjamin, Abid Khan, Laura K Mann, Caleb Mentzer, Vasileios Mousafeiris, Francesk Mulita, Shari Reid-Gruner, Erica Sais, Christopher Foote, Carlos Palacio-Lascano, Dias Argandykov, Haytham Kaafarani, Michelle Bover Manderski, Mayur Narayan, Mark J Seamon
BACKGROUND: Leak following surgical repair of traumatic duodenal injuries results in prolonged hospitalization and oftentimes nil per os(NPO) treatment. Parenteral nutrition(PN) has known morbidity; however, duodenal leak(DL) patients often have complex injuries and hospital courses resulting in barriers to enteral nutrition(EN). We hypothesized EN alone would be associated with 1)shorter duration until leak closure and 2)less infectious complications and shorter hospital length of stay(HLOS) compared to PN...
May 15, 2024: Journal of Trauma and Acute Care Surgery
#75
JOURNAL ARTICLE
Henri de Lesquen, Raphael Paris, Solenn Lacheze, Bruno de la Villeon, William Menini, Antoine Lamblin, Anthony Vacher, Paul Balandraud, Pierre Pasquier, Jean-Philippe Avaro
BACKGROUND: The purpose of this article is to describe the development of a crew resource management (CRM) training course dedicated for the forward surgical teams (FSTs) of the French Military Health Service. METHODS: Since 2021, the predeployment training of French FSTs has included a simulation-based curriculum consisting of organizational and human factors. It combines lectures, laboratory exercises, and situational training exercises to consider four fundamental "nontechnical" (cognitive and social) skills for effective and safe combat casualty care: (a) leadership, (b) decision-making, (c) coordination, and (d) situational awareness...
May 15, 2024: Journal of Trauma and Acute Care Surgery
#76
JOURNAL ARTICLE
Richard T Roden, Kevin L Webb, Wyatt W Pruter, Ellen K Gorman, David R Holmes, Clifton R Haider, Michael J Joyner, Timothy B Curry, Chad C Wiggins, Victor A Convertino
BACKGROUND: The Compensatory Reserve Metric (CRM) provides a time sensitive indicator of hemodynamic decompensation. However, its in-field utility is limited due to the size and cost-intensive nature of standard vital sign monitors or photoplethysmographic volume-clamp (PPGVC) devices used to measure arterial waveforms. In this regard, photoplethysmographic measurements obtained from pulse oximetry (PPGPO) may serve as a useful, portable alternative. This study aimed to validate CRM values obtained using PPGPO...
May 15, 2024: Journal of Trauma and Acute Care Surgery
#77
JOURNAL ARTICLE
Benjamin W Stocker, Ian S LaCroix, Christopher Erickson, Lauren T Gallagher, Benjamin J Ramser, Otto Thielen, William Hallas, Sanchayita Mitra, Ernest E Moore, Kirk Hansen, Angelo D'Alessandro, Christopher C Silliman, Mitchell J Cohen
BACKGROUND: Patients with type O blood may have an increased risk of hemorrhagic complications due to lower baseline levels of von Willebrand Factor (vWF) and factor VIII, but the transition to a mortality difference in trauma is less clear. We hypothesized that type O trauma patients will have differential proteomic and metabolomic signatures in response to trauma beyond vWF and FVIII alone. METHODS: Patients meeting the highest level of trauma activation criteria were prospectively enrolled...
May 15, 2024: Journal of Trauma and Acute Care Surgery
#78
JOURNAL ARTICLE
Bruno Evrard, Pratik Sinha, Kevin Delucchi, Carolyn M Hendrickson, Kirsten N Kangelaris, Kathleen D Liu, Andrew Willmore, Nelson Wu, Lucile Neyton, Emma Schmiege, Antonio Gomez, V Eric Kerchberger, Ann Zalucky, Michael A Matthay, Lorraine B Ware, Carolyn S Calfee
BACKGROUND: Hypoinflammatory and hyperinflammatory phenotypes have been identified in both Acute Respiratory Distress Syndrome (ARDS) and sepsis. Attributable mortality of ARDS in each phenotype of sepsis is yet to be determined. We aimed to estimate the population attributable fraction of death from ARDS (PAFARDS ) in hypoinflammatory and hyperinflammatory sepsis, and to determine the primary cause of death within each phenotype. METHODS: We studied 1737 patients with sepsis from two prospective cohorts...
May 14, 2024: Critical Care: the Official Journal of the Critical Care Forum
#79
JOURNAL ARTICLE
John R Blakeman, Susana J Calderon, Susie Watkins, MyoungJin Kim, Kate Peterson, Marilyn A Prasun
BACKGROUND: Little attention has been placed on language proficiency as a potential variable affecting ACS symptom knowledge, attitudes, and beliefs. OBJECTIVES: To compare the ACS symptom knowledge, attitudes, and beliefs of Hispanic and Latina/o/x/e individuals proficient in English and in those only proficient in Spanish. Secondary aims were to determine if there were differences in ACS symptom knowledge, attitudes, or beliefs based on participants' previous exposure to ACS symptom information and to evaluate instrument characteristics of the new Spanish version of the ACS Response Index...
May 13, 2024: Heart & Lung: the Journal of Critical Care
#80
REVIEW
Heather L Gornik, Herbert D Aronow, Philip P Goodney, Shipra Arya, Luke Packard Brewster, Lori Byrd, Venita Chandra, Douglas E Drachman, Jennifer M Eaves, Jonathan K Ehrman, John N Evans, Thomas S D Getchius, J Antonio Gutiérrez, Beau M Hawkins, Connie N Hess, Karen J Ho, W Schuyler Jones, Esther S H Kim, Scott Kinlay, Lee Kirksey, Debra Kohlman-Trigoboff, Chandler A Long, Amy West Pollak, Saher S Sabri, Lawrence B Sadwin, Eric A Secemsky, Maya Serhal, Mehdi H Shishehbor, Diane Treat-Jacobson, Luke R Wilkins
AIM: The "2024 ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS Guideline for the Management of Lower Extremity Peripheral Artery Disease" provides recommendations to guide clinicians in the treatment of patients with lower extremity peripheral artery disease across its multiple clinical presentation subsets (ie, asymptomatic, chronic symptomatic, chronic limb-threatening ischemia, and acute limb ischemia). METHODS: A comprehensive literature search was conducted from October 2020 to June 2022, encompassing studies, reviews, and other evidence conducted on human subjects that was published in English from PubMed, EMBASE, the Cochrane Library, CINHL Complete, and other selected databases relevant to this guideline...
May 14, 2024: Circulation
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