Sofie P G Henckens, Dajia Liu, Suzanne S Gisbertz, Marianne C Kalff, Maarten C J Anderegg, David Crull, Freek Daams, Annette D van Dalsen, Jan Willem T Dekker, Marc J van Det, Peter van Duijvendijk, Wietse J Eshuis, Richard P R Groenendijk, Jan Willem Haveman, Richard van Hillegersberg, Misha D P Luyer, Pim B Olthof, Jean-Pierre E N Pierie, Victor D Plat, Camiel Rosman, Jelle P Ruurda, Johanna W van Sandick, Meindert N Sosef, Daan M Voeten, Guy H E J Vijgen, Maarten F Bijlsma, Sybren L Meijer, Maarten C C M Hulshof, Cesar Oyarce, Sjoerd M Lagarde, Hanneke W M van Laarhoven, Mark I van Berge Henegouwen
BACKGROUND: This study evaluated the association of pathological tumour response (tumour regression grade, TRG) and a novel scoring system, combining both TRG and nodal status (TRG-ypN score; TRG1-ypN0, TRG>1-ypN0, TRG1-ypN+ and TRG>1-ypN+), with recurrence patterns and survival after multimodal treatment of oesophageal adenocarcinoma. METHODS: This Dutch nationwide cohort study included patients treated with neoadjuvant chemoradiotherapy followed by oesophagectomy for distal oesophageal or gastro-oesophageal junctional adenocarcinoma between 2007 and 2016...
January 31, 2024: British Journal of Surgery