Benneth Ben-Azu, Christian I Uruaka, Abayomi M Ajayi, Thiophilus Aghogho Jarikre, Kingsley E Nwangwa, Kingsley C Chilaka, Bienose S Chijioke, Marymagdalene G Omonyeme, Chineye B Ozege, Emmanuella C Ofili, Ebidenara B Warekoromor, Nwanneka L Edigbue, Ufoma V Esiekpe, Dabrechi E Akaenyi, Gladys O Agu
Schizophrenia is a life disabling, multisystem neuropsychiatric disease mostly derived from complex epigenetic-mediated neurobiological changes causing behavioural deficits. Neurochemical disorganizations, neurotrophic and neuroimmune alterations are some of the challenging neuropathologies proving unabated during psychopharmacology of schizophrenia, further bedeviled by drug-induced metabolic derangements including alteration of amino acids. In first-episode schizophrenia patients, taurine, an essential β-amino acid represses psychotic-symptoms...
November 9, 2022: Neurochemical Research