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Francesco Craig, Andrea De Giacomo, Francesca F Operto, Mariella Margari, Antonio Trabacca, Lucia Margari
BACKGROUND: The aim of current study was to examine the nature and prevalence of feeding problems and mealtime behavior problems in children with ASD comparing to children with other neurodevelopmental disorders (NNDs) and TD children. We also investigated the impact of intelligence quotient (IQ) and/or emotional and behavioral problems on feeding and mealtime behavior problems. METHODS: Participants completed the following tests: Social Communication Questionnaire (SCQ), Child Behavior Checklist (CBCL), Brief Autism Mealtime Behavior Inventory (BAMBI) and Behavioral Pediatric Feeding Assessment Scale (BPFAS)...
February 13, 2019: Minerva Pediatrica
Xinjian Li, Jianwei Ye, Xuelei Han, Ruimin Qiao, Xiuling Li, Gang Lv, Kejun Wang
Reproductive performance is a complex quantitative trait, that is determined by multiple genes, regulatory pathways and environmental factors. A list of major genes with large effect have been detected, although multiple QTLs are identified. To identify candidate genes for pig prolificacy, whole genome variants from five high- and five low-prolificacy Yorkshire sows were collected using whole-genome resequencing. A total of 13,955,609 SNPs and 2,666,366 indels were detected across the genome. Common differential SNPs and indels were identified between the two groups of sows...
January 29, 2019: Genomics
Kathleen Ahern Gould
No abstract text is available yet for this article.
March 2019: Dimensions of Critical Care Nursing: DCCN
Andrew M Koth, Claudia A Algaze, Charlotte Sakarovitch, Jin Long, Komal Kamra, Gail E Wright, Bambi Alexander-Banys, Katsuhide Maeda, Andrew Y Shin
OBJECTIVE: This study sets out to determine the influence of age at the time of surgery as a risk factor for post-operative length of stay after bidirectional cavopulmonary anastomosis. METHODS: All patients undergoing a Glenn procedure between January 2010 and July 2015 were included in this retrospective cohort study. Demographic data were examined. Standard descriptive statistics was used. A univariable analysis was conducted using the appropriate test based on data distribution...
January 30, 2019: Cardiology in the Young
Simonetta Panerai, Grazia Silvana Suraniti, Valentina Catania, Rosalba Carmeci, Maurizio Elia, Raffaele Ferri
AIM: Feeding problems are documented in several developmental disabilities. This paper aims to present early results from the implementation of a day-center, multidisciplinary, intensive, behaviorally-based treatment package for feeding problems, delivered to children with developmental disabilities, namely Autism Spectrum Disorder (ASD) and Intellectual Disability (ID). METHODS: This is a quasi-experimental design study. Both an AB design (measures were administered at pre- and post-treatment times) and a comparison design were used; a follow-up was carried out after one year from the end of the treatment...
November 2018: Rivista di Psichiatria
Alberto Lucchini, Stefano Elli, Flora Bianchi, Nicoletta Doina Birleanu, Silvia Zucchini, Stefania Ceccarelli, Valeria Tancredi, Erica Zampieri, Daniele Moretta, Stefano Bambi
. Incidence and risk factors associated with the development of pressure ulcers in an Italian general intensive care unit. INTRODUCTION: Pressure ulcers (PU) represent one of the most frequent adverse event in intensive care units (ICU). Critical patients are at higher risk of developing a PU, with an incidence between 3.3-39.3%. AIM: To assess the incidence and risk factors for developing PUs in a general ICU of an Italian University hospital. METHODS: Retrospective observational study on a sample of 122 patients admitted to a general intensive care unit, from January to December 2015, with a length of ICU stay > 5 days...
October 2018: Assistenza Infermieristica e Ricerca: AIR
Francesca Ceci, Linda D'Amore, Maria Romana Grimaldi, Elena Annesi, Lucia Bambi, Paolo Bruzzone, Paolo Negro, Francesco Gossetti
Central Mesh Failure (CMF) after abdominal wall repair (AWR) is uncommon but should be considered in case of recurrence. The mechanism is unclear and different theories are actually proposed, as the action of opposite forces acting in the abdominal wall on the prosthesis, and the characteristics of the device to be implanted. The use of lightweight meshes in some cases could be inadequate to withstand the bursting strenght of the abdominal wall. Three cases of incisional hernia recurrence due to central mesh failure are here reported...
2018: Annali Italiani di Chirurgia
Xiangping Yao, Taiyong Yu, Fengxue Xi, Yanting Xu, Lu Ma, Xiaohan Pan, Shujie Chen, Mulan Han, Yulong Yin, Xiaoshuang Dai, Guohuan Xu, Huabing Zhang, Gongshe Yang, Liwei Xie
Bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) gene encodes a transmembrane protein and is involved in multiple physiological and pathological processes, such as inflammatory response, tumor development and progression, cell proliferation and differentiation. A previous study suggested that BAMBI may interact with the Wnt/β-catenin signaling pathway via promoting β-catenin nuclear translocation associated with C2C12 myogenic myoblast differentiation. However, its biological function in skeletal muscle still remains unknown and requires further characterization...
December 20, 2018: Biochemical and Biophysical Research Communications
Jian Yin, Xuhui Hou, Songbai Yang
microRNAs (miRNAs) have been revealed to participate in the pathological process of atherosclerosis (AS). However, the exact role of miR-338-3p, a target miRNA of BMP and activin membrane-bound inhibitor (BAMBI), and its possible molecular mechanism in AS remain unidentified. In this study, we found that BAMBI was significantly decreased, whereas miR-338-3p increased in patients with AS and oxidized low-density lipoprotein (ox-LDL)-induced HUVEC cells. Furthermore, overexpression of miR-338-3p significantly decreased cell viability and elevated cell apoptosis, whereas its inhibition significantly promoted cell viability and inhibited cell apoptosis in ox-LDL-induced HUVEC cells...
December 17, 2018: Journal of Cellular Physiology
Alberto Lucchini, Stefano Bambi, Alessandro Galazzi, Stefano Elli, Cristina Negrini, Stefania Vaccino, Silvia Triantafillidis, Alessandra Biancardi, Mattia Cozzari, Roberto Fumagalli, Giuseppe Foti
BACKGROUND AND AIM: Unplanned extubation (UE) in Intensive Care Units (ICU) is an indicator of quality and safety of care. UEs are classified in: accidental extubations, if involuntarily caused during nursing care or medical procedures; self-extubation, if determined by the patient him/herself.  In scientific literature, the cumulative incidence of UEs varies from 0.3% to 35.8%. The aim of this study is to explore the incidence of UEs in an Italian university general ICU adopting a well-established protocol of tracheal tube nursing management and fixation...
December 7, 2018: Acta Bio-medica: Atenei Parmensis
Enrico Bulleri, Cristian Fusi, Stefano Bambi, Luigi Pisani
BACKGROUND: Mechanical ventilation is often employed as partial ventilatory support where both the patient and the ventilator work together. The ventilator settings should be adjusted to maintain a harmonious patient-ventilator interaction. However, this balance is often altered by many factors able to generate a patient ventilator asynchrony (PVA). The aims of this review were: to identify PVAs, their typologies and classifications; to describe how and to what extent their occurrence can affect the patients' outcomes; to investigate the levels of nursing skill in detecting PVAs...
December 7, 2018: Acta Bio-medica: Atenei Parmensis
Stefano Bambi, Andrea Guazzini, Michela Piredda, Alberto Lucchini, Maria Grazia De Marinis, Laura Rasero
BACKGROUND: Lateral violence and bullying affect nurses' professional and health status. Worldwide prevalence ranges from 1% to 87%. AIM: To investigate prevalence and risk factors of lateral violence and bullying among Italian nurse peers in different work settings, inside and outside hospitals. METHODS: Web survey using the 17-item "Negative Interactions Among Nurses Questionnaire." Emails were sent to 5,009 nurses in three Tuscan public health care institutions...
December 1, 2018: Journal of Nursing Management
Giulia Golinelli, Giulia Grisendi, Malvina Prapa, Marco Bestagno, Carlotta Spano, Filippo Rossignoli, Franco Bambi, Iacopo Sardi, Monica Cellini, Edwin M Horwitz, Alberto Feletti, Giacomo Pavesi, Massimo Dominici
Tumor targeting by genetically modified mesenchymal stromal/stem cells (MSCs) carrying anti-cancer molecules represents a promising cell-based strategy. We previously showed that the pro-apoptotic agent tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can be successfully delivered by MSCs to cancer sites. While the interaction between TRAIL and its receptors is clear, more obscure is the way in which MSCs can selectively target tumors and their antigens. Several neuroectoderm-derived neoplasms, including glioblastoma (GBM), sarcomas, and neuroblastoma, express high levels of the tumor-associated antigen GD2...
November 22, 2018: Cancer Gene Therapy
Alberto Lucchini, Stefano Elli, Stefano Bambi, Christian De Felippis, Simona Vimercati, Dario Minotti, Sara Pasquali, Luigi Cannizzo, Roberto Fumagalli, Giuseppe Foti
BACKGROUND: Prolonged application time of helmet continuous positive airway pressure (CPAP) leads to better outcomes, but its timing can be influenced by the patient's tolerance. AIMS AND OBJECTIVES: To investigate patients' pain and tolerance experience related to different options of helmet fixing system: 'armpits strap' versus 'counterweights system'. DESIGN: This was a non-randomized crossover study performed in a 10-bed intensive care unit and referral extra corporeal membrane oxigenation (ECMO) centre of an Italian university hospital...
November 20, 2018: Nursing in Critical Care
Francesca Ceci, Linda D'Amore, Elena Annesi, Lucia Bambi, Maria Romana Grimaldi, Francesco Gossetti, Paolo Negro
INTRODUCTION: Meshes are commonly employed in abdominal hernia repair to reduce recurrence rates. Prosthetic repair, however, increases the risk of mesh related complications, including migration into adjacent viscera and erosion which can occur as uncommon and can be difficult to be diagnose. PRESENTATION OF CASE: This is a case of transmural migration of composite mesh into the bowel, presenting as chronic abdominal pain and anemia 14 years after incisional hernia repair...
October 12, 2018: International Journal of Surgery Case Reports
Daniele Campa, Martina Matarazzi, William Greenhalf, Maarten Bijlsma, Kai-Uwe Saum, Claudio Pasquali, Hanneke van Laarhoven, Andrea Szentesi, Francesca Federici, Pavel Vodicka, Niccola Funel, Raffaele Pezzilli, H Bas Bueno-de-Mesquita, Ludmila Vodickova, Daniela Basso, Ofure Obazee, Thilo Hackert, Pavel Soucek, Katarina Cuk, Jörg Kaiser, Cosimo Sperti, Martin Lovecek, Gabriele Capurso, Beatrice Mohelnikova-Duchonova, Kay-Tee Khaw, Anna-Katharina König, Juozas Kupcinskas, Rudolf Kaaks, Franco Bambi, Livia Archibugi, Andrea Mambrini, Giulia Martina Cavestro, Stefano Landi, Péter Hegyi, Jakob R Izbicki, Domenica Gioffreda, Carlo Federico Zambon, Francesca Tavano, Renata Talar-Wojnarowska, Krzysztof Jamroziak, Timothy J Key, Gianfranco Delle Fave, Oliver Strobel, Laimas Jonaitis, Angelo Andriulli, Rita T Lawlor, Felice Pirozzi, Verena Katzke, Chiara Valsuani, Yogesh K Vashist, Hermann Brenner, Federico Canzian
Telomere deregulation is a hallmark of cancer. Telomere length measured in lymphocytes (LTL) has been shown to be a risk marker for several cancers. For pancreatic ductal adenocarcinoma (PDAC) consensus is lacking whether risk is associated with long or short telomeres. Mendelian randomization approaches have shown that a score built from SNPs associated with LTL could be used as a robust risk marker. We explored this approach in a large scale study within the PANcreatic Disease ReseArch (PANDoRA) consortium...
October 16, 2018: International Journal of Cancer. Journal International du Cancer
Hong-Ju Liu, Gang Chen, Long Chen, Mei Zhou, Xian-Zhi Xiong, Zhao-Ji Meng, Sheng-Wen Sun, Xiao-Nan Tao
In CD4+ T helper (Th) cells, transforming growth factor β (TGF‑β) is indispensable for the induction of both regulatory T (Treg) and interleukin‑17‑producing effector T helper (Th17) cells. Although BMP and activin membrane‑bound inhibitor (BAMBI) is part of a rheostat‑like mechanism for the regulation of TGF‑β signalling and autoimmune arthritis in mouse models, the underlying activity of BAMBI on the human Th17/Treg cell axis, particularly during exposure to cigarette smoke, remains to be elucidated...
October 9, 2018: International Journal of Molecular Medicine
Carlos A Ramos, Rayne Rouce, Catherine S Robertson, Amy Reyna, Neeharika Narala, Gayatri Vyas, Birju Mehta, Huimin Zhang, Olga Dakhova, George Carrum, Rammurti T Kamble, Adrian P Gee, Zhuyong Mei, Meng-Fen Wu, Hao Liu, Bambi Grilley, Cliona M Rooney, Helen E Heslop, Malcolm K Brenner, Barbara Savoldo, Gianpietro Dotti
Second-generation (2G) chimeric antigen receptors (CARs) targeting CD19 are highly active against B cell malignancies, but it is unknown whether any of the costimulatory domains incorporated in the CAR have superior activity to others. Because CD28 and 4-1BB signaling activate different pathways, combining them in a single third-generation (3G) CAR may overcome the limitations of each individual costimulatory domain. We designed a clinical trial in which two autologous CD19-specific CAR-transduced T cell products (CD19...
September 13, 2018: Molecular Therapy: the Journal of the American Society of Gene Therapy
Michael A Motes, Jeffrey S Spence, Matthew R Brier, Hsueh-Sheng Chiang, Bambi L DeLaRosa, Justin Eroh, Mandy J Maguire, Raksha A Mudar, Gail D Tillman, Michael A Kraut, John Hart
To investigate differences in inhibitory control and processing speed over the life span, participants in 7- to 8-, 10- to 11-, 12- to 15-, 18- to 25-, and 54- to 80-year-old age cohorts completed a Go/No-Go task requiring varying levels of semantic categorization. Discriminant function analysis of correct rejection rates (CRRs), hit rates (HRs), and reaction times (RTs) revealed a function on which CRR loaded positively and RT loaded negatively, across categorization levels. Scores increased from youngest to the younger adult cohort and decreased for the older adult cohort...
October 4, 2018: Psychology and Aging
Alberto Lucchini, Stefano Bambi, Christian de Felippis, Alessandro Galazzi, Grazia Addis, Roberto Rona, Giacomo Grasselli, Antonio Pesenti, Roberto Fumagalli, Giuseppe Foti
INTRODUCTION: Oral care, using either a mouth rinse, gel, toothbrush, or combination of them, together with aspiration of secretions, may reduce the risk of ventilator-acquired pneumonia in intubated patents. Oral care procedure in patients on venovenous extracorporeal membrane oxygenation (VV-ECMO) may cause bleeding due to the systemic anticoagulation required. PURPOSE: The aim of this study was to investigate the rate of bleeding episodes during oral care in patients supported by VV-ECMO...
November 2018: Dimensions of Critical Care Nursing: DCCN
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