Amanda Lewis, Madeleine Clout, Jonathan Benger, Philip Braude, Nicholas Turner, James Gagg, Emma Gendall, Simon Holloway, Jenny Ingram, Rebecca Kandiyali, Nick Maskell, David Shipway, Jason E Smith, Jodi Taylor, Alia Darweish-Medniuk, Edward Carlton
BACKGROUND: Topical lidocaine patches, applied over rib fractures, have been suggested as a non-invasive method of local anaesthetic delivery to improve respiratory function, reduce opioid consumption and consequently reduce pulmonary complications. Older patients may gain most benefit from improved analgesic regimens yet lidocaine patches are untested as an early intervention in the Emergency Department (ED). The aim of this trial is to investigate uncertainties around trial design and conduct, to establish whether a definitive randomised trial of topical lidocaine patches in older patients with rib fractures is feasible...
2023: NIHR Open Res