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JOURNAL ARTICLE
Juan V Llau, César Aldecoa, Emilia Guasch, Pascual Marco, Pilar Marcos-Neira, Pilar Paniagua, José A Páramo, Manuel Quintana, F Javier Rodríguez-Martorell, Ainhoa Serrano
This document is an update of the multidisciplinary document HEMOMAS, published in 2016 with the endorsement of the Spanish Scientific Societies of Anaesthesiology (SEDAR), Intensive Care (SEMICYUC) and Thrombosis and Haemostasis (SETH). The aim of this document was to review and update existing recommendations on the management of massive haemorrhage. The methodology of the update was based on several elements of the ADAPTE method by searching and adapting guidelines published in the specific field of massive bleeding since 2014, plus a literature search performed in PubMed and EMBASE from January 2014 to June 2021...
2023: Revista española de anestesiología y reanimación
#2
Juan V Llau, César Aldecoa, Emilia Guasch, Pascual Marco, Pilar Marcos-Neira, Pilar Paniagua, José A Páramo, Manuel Quintana, F Javier Rodríguez-Martorell, Ainhoa Serrano
This document is an update of the multidisciplinary document HEMOMAS, published in 2016 with the endorsement of the Spanish Scientific Societies of Anaesthesiology (SEDAR), Intensive Care (SEMICYUC) and Thrombosis and Haemostasis (SETH). The aim of this document was to review and update existing recommendations on the management of massive haemorrhage. The methodology of the update was based on several elements of the ADAPTE method by searching and adapting guidelines published in the specific field of massive bleeding since 2014, plus a literature search performed in PubMed and EMBASE from January 2014 to June 2021...
August 2023: Medicina intensiva
#3
JOURNAL ARTICLE
J M Castro García, J J Arenas-Jiménez, A Ureña-Vacas, E García-Garrigós, P Sirera-Sirera
BACKGROUND AND AIMS: To analyze the diagnostic performance of pulmonary CT angiography and to compare different D-dimer cutoffs for the diagnosis of acute pulmonary embolism in patients with and without SARS-CoV-2 infections. MATERIALS AND METHODS: We retrospectively analysed all consecutive pulmonary CT angiography studies done for suspected pulmonary embolism in a tertiary hospital during two time periods: the first December 2020 through February 2021 and the second December 2017 through February 2018...
2023: Radiología
#4
JOURNAL ARTICLE
Li-Hua Lin, Hong Liu, Dong-Hua Jin, Jun Zou, Yu-Xian Xie, Hong Qiu, Miao Jia, Da-Mei Li, Bi-Cheng Liu
OBJECTIVES: This study was to explore the potential relationship between the fibrinogen-to-albumin ratio (FAR) and the presence and severity of coronary artery disease (CAD) in stage 3-5 predialysis chronic kidney disease (CKD) patients. DESIGN: This study included 978 patients undergoing coronary angiography (CAG). CAD was defined as the presence of obstructive stenosis>50% of the lumen diameter in any of the four main coronary arteries. Gensini scores (GSs), left main coronary artery (LMCA) and three-vessel coronary artery disease (TVD) were used to elevate the severity of CAD...
November 16, 2022: Nefrología
#5
JOURNAL ARTICLE
R Jaime-Romo, F Vidal-Cervantes, A H Rivera-Villa, A Colín-Vázquez
INTRODUCTION: Total hip arthroplasty is popular for its success in treating coxarthrosis, its associated with substantial blood loss. Significant bleeding causes complications such as increase in hospitalization days, higher costs, exposing the patient to complications associated with blood transfusion. The aim of the study is to investigate the association between preoperative plasma fibrinogen concentration and trans-surgical bleeding and determine fibrinogen level cut-off to present greater trans-surgical bleeding...
November 2021: Acta Ortopédica Mexicana
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REVIEW
Cecilia Guillermo-Esposito, Patricia Casais, Gabriela Cesarman-Maus, Fernanda Andrade-Orsi, Rosario Martínez-Rovira, Joao C de-Campos-Guerra, Suely M Rezende, Raúl Izaguirre-Ávila, Raúl Altman, José Ceresetto, Cecilia Colorio, Cristina Duboscq, Claudio Martín Rosa, Soledad Molnar, Diana García, Mario Luis Tejarina, Nelson Nina García, Juan Choque Pacheco, Chiara Chindamo J. María, Gloria Ramos Ramos, Guillermo León Basantes, Aura Milena Reyna, Miriam Cantero Guevara, Mateo Porres Aguilar, Luis Meillón, Flavio Adrián Grimaldo, Ludwing Alexander Bacon Fonseca, Al Ávila Milord, Ricardo Aguilar, Rafael Aparicio, Paula de Guggiari, Gloria Chumpitaz, Pedro Pablo García, Blanca Steffano, Sandra Damiano, Juan Serrano, Marisol Zavahra
Coagulopathy and thrombosis associated with coronavirus disease 2019 (COVID-19) represent a major issue in the management of this disease. In the past months, clinical studies have demonstrated that COVID-19 patients present with a particular hypercoagulable state, in which a markedly increased D-dimer concomitant with increased levels of fibrinogen are observed. This hypercoagulable state leads to an increased risk of thrombosis, which seems to be higher among those patients with critical symptoms of COVID-19...
December 20, 2021: Archivos de Cardiología de México
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JOURNAL ARTICLE
Oswaldo Nina-Cueva, Derly Olazabal-Chambilla, Jair Quispe-Arpasi, Adell Alzamora-Sánchez, Mauricio Gomes-Heleno, Salomón Huancahuire-Vega
Introduction: Snakebite envenoming is considered by the World Health Organization (WHO) as a neglected tropical disease. Currently, Bothrops snake venoms are being studied intensively, but there is little knowledge about Bothrops roedingeri venom. Objectives: To biochemically characterize B. roedingeri total venom and evaluate its myotoxic, edematogenic, and hemorrhagic activity. Materials and methods: We characterized B. roedingeri venom enzymatic activity by determining the phospholipase A2 and the proteolytic and fibrinogenolytic action using SDSPAGE electrophoresis while we characterized its venom toxicity by determining the minimum hemorrhagic dose, the minimum edema dose, and the local and systemic myotoxic effects...
December 2, 2020: Biomédica: Revista del Instituto Nacional de Salud
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JOURNAL ARTICLE
Roberta Rolla, Andreana De Mauri, Matteo Vidali, Ambra Valsesia, Doriana Chiarinotti, Giorgio Bellomo
BACKGROUND: Cardiovascular diseases are the leading cause of morbidity and mortality in hemodialysis patients (HP). The aim of the study was to analyze a series of polymorphisms (known to be associated with increased cardiovascular risk in the general population) in HP, in order to better understand the mechanisms of cardiovascular disease and to find new prevention strategies. METHODS: 102 hemodialysis patients were investigated for polymorphisms associated with increased cardiovascular risk in unselected population (FV Leiden R506Q; FV H1299R; FII G20210A; PAI-1 var 4G/5G; GpIIIA T1565C; FXIII var G/T; β-FIBRINOGENO var G/A; ACE I/D; AGT var M/T; ATR-1A1166C; APOE T112C; APOE T158C; MTHFR C677T; MTHFR A1298C; CBS 844ins68)...
2016: Clinical Laboratory
#9
COMPARATIVE STUDY
E J Oudijk, H K Nieuwenhuis, R Bos, R Fijnheer
The bleeding syndrome of acute promyelocytic leukemia (APL) is complex and consists of disseminated intravascular coagulation (DIC) and hyperfibrinolysis. Elastase, derived from malignant promyelocytes, is believed to mediate the fibrinogeno- and fibrinolysis by aspecific proteolysis. In this study we measured the role of elastase in fifteen patients with APL by using an assay for elastase degraded fibrin(ogen) and the results were compared with those obtained in patients with sepsis induced DIC. High levels of elastase were observed in sepsis and APL...
June 2000: Thrombosis and Haemostasis
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