Yaqing Shu, Youming Long, Yanyu Chang, Rui Li, Xiaobo Sun, Yuge Wang, Yinong Huang, Jing Li, Jianning Chen, Yu Yang, Zhengqi Lu, Xueqiang Hu, Allan G Kermode, Wei Qiu
BACKGROUND: Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a novel meningoencephalomyelitis. However, the pathogenesis of this disease is unclear. We therefore examined a brain biopsy from a patient with autoimmune GFAP astrocytopathy by immunohistopathology. METHODS: We examined brain biopsy sections from a patient with autoimmune GFAP astrocytopathy using hematoxylin and eosin (HE) and Luxol fast blue (LFB) staining, and immunostaining with antibodies for CD4, CD8, CD3, CD20, CD68, CD138, Neu-N, GFAP, myelin oligodendrocyte glycoprotein (MOG), and aquaporin-4 (AQP4)...
2018: Neuroimmunomodulation