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JOURNAL ARTICLE
Justin E Vranic, Adam A Dmytriw, Inka K Berglar, Naif M Alotaibi, Nicole M Cancelliere, Christopher J Stapleton, James D Rabinov, Pablo Harker, Rajiv Gupta, Joshua D Bernstock, Matthew J Koch, Scott B Raymond, Justin R Mascitelli, T Tyler Patterson, Joshua Seinfeld, Andrew White, David Case, Christopher Roark, Chirag D Gandhi, Fawaz Al-Mufti, Jared Cooper, Charles Matouk, Nanthiya Sujijantarat, Diego A Devia, Maria I Ocampo-Navia, Daniel E Villamizar-Torres, Juan C Puentes, Mohamed M Salem, Ammad Baig, Kareem El Namaani, Anna Luisa Kühn, Bryan Pukenas, Brian T Jankowitz, Jan Karl Burkhardt, Adnan Siddiqui, Pascal Jabbour, Jasmeet Singh, Ajit S Puri, Robert W Regenhardt, Vitor Mendes Pereira, Aman B Patel
BACKGROUND AND OBJECTIVES: Dual antiplatelet therapy (DAPT) is necessary to minimize the risk of periprocedural thromboembolic complications associated with aneurysm embolization using pipeline embolization device (PED). We aimed to assess the impact of platelet function testing (PFT) on reducing periprocedural thromboembolic complications associated with PED flow diversion in patients receiving aspirin and clopidogrel. METHODS: Patients with unruptured intracranial aneurysms requiring PED flow diversion were identified from 13 centers for retrospective evaluation...
April 18, 2024: Neurosurgery
#2
REVIEW
Hanan Anwar Rusidi, Rohadi Muhammad Rosyidi, Dewa Putu Wisnu Wardhana, Wisnu Baskoro, Geizar Arsika Ramadhana
BACKGROUND: Inflammatory processes play an important role in the aggressiveness of a tumor. However, the relationship between inflammatory markers in meningioma grade is not well known. Knowledge of preoperative meningioma grade plays an important role in the prognosis and treatment of this tumor. This study aims to assess preoperative hematological inflammatory markers as a predictor of the pathological grade of meningioma. METHODS: To ensure comprehensive retrieval of relevant studies, we searched the following key databases, PubMed, Science Direct, and Biomed Central, with evidence related to preoperative hematological inflammatory markers among meningioma up to September 2023...
2024: Surgical Neurology International
#3
JOURNAL ARTICLE
Kota Kurisu, Toshiya Osanai, Yutaka Morishima, Masaki Ito, Haruto Uchino, Taku Sugiyama, Miki Fujimura
PURPOSE: The systemic immune-inflammation index (SII), a marker of systemic inflammation, can be calculated using peripheral blood tests. Although the SII has been reported as a feasible biomarker in various cerebrovascular diseases, no studies have explored in dural arteriovenous fistula (DAVF). A retrospective cohort study was performed to test whether the SII reflects the clinical characteristics of DAVF and whether this index could serve as a feasible biomarker. METHODS: This study included 28 patients who underwent endovascular treatment (39 sessions) for DAVF between 2014 and 2023...
April 16, 2024: Acta Neurochirurgica
#4
I-Wen Chen, Li-Chen Chang, Kuo-Chuan Hung
No abstract text is available yet for this article.
April 3, 2024: World Neurosurgery
#5
JOURNAL ARTICLE
Curtis R Ginder, Giselle A Suero-Abreu, Saad S Ghumman, Brian A Bergmark, Omar Arnaout, Robert P Giugliano
The management of perioperative acute myocardial infarction (AMI) following oncologic neurosurgery requires balancing competing risks of myocardial ischemia and postoperative bleeding. There are limited human data to establish the safest timing of antiplatelet or anticoagulation therapy following neurosurgical procedures. For patients with malignancy experiencing AMI in the acute postoperative period, staged percutaneous coronary intervention (PCI) with upfront coronary aspiration thrombectomy followed by delayed completion PCI may offer an opportunity for myocardial salvage while minimizing postoperative bleeding risks...
March 27, 2024: Cardiology and Therapy
#6
JOURNAL ARTICLE
Samil Dikici
AIM: To evaluate systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), multi-inflammatory index (MII), and prognostic nutrition index (PNI), and to compare them with the previously reported inflammation-related hematologic index in lumbar discectomy (LD). MATERIAL AND METHODS: This was a retrospective, cross-sectional, single-center study with 105 consecutive patients who underwent surgery for LD. The study comprised three groups: Group I included data from healthy participants, Group II included data before LD, and Group III included data after LD...
2024: Turkish Neurosurgery
#7
JOURNAL ARTICLE
Frederik Denorme, Juhana Frösen, Annukka Jouppila, Antti Lindgren, Julio C Resendiz-Nieves, Hannu Manninen, Simon F De Meyer, Riitta Lassila
BACKGROUND: Several neurovascular procedures require temporary occlusion of cerebral arteries, leading to ischemia of unpredictable length, occasionally causing brain infarction. Experimental models of cerebral ischemia-reperfusion injury have established that platelet adhesion and coagulation play detrimental roles in reperfusion injury following transient cerebral ischemia. Therefore, in a model of cerebral ischemia-reperfusion injury (IRI), we investigated the therapeutic potential of a dual antiplatelet and anticoagulant (APAC) heparin proteoglycan mimetic which is able to bind to vascular injury sites...
March 15, 2024: Acta Neurochirurgica
#8
JOURNAL ARTICLE
I-Wen Chen, Li-Chen Chang, Kuo-Chuan Hung
No abstract text is available yet for this article.
March 2024: World Neurosurgery
#9
JOURNAL ARTICLE
Eyup Bayatli, Onur Ozgural, Ihsan Dogan, Omer Mert Ozpiskin, Siavash Hasimoglu, Yusuf Cem Kuzukiran, Murat Zaimoglu, Umit Eroglu, Gokmen Kahilogullari, Hasan Caglar Ugur, Y Sukru Caglar
OBJECTIVE: Predicting the aggressiveness of meningiomas may influence the surgical strategy timing. Because of the paucity of robust markers, the systemic immune-inflammation (SII) index is a novel biomarker to be an independent predictor of poor prognosis in various cancers including gliomas. We aimed to investigate the value of SII as well as neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) indices in predicting prognosis. METHODS: Records including demographic, clinical, and laboratory datas of patients operated on due to intracranial meningioma in 2017-2023 were retrospectively reviewed...
March 5, 2024: World Neurosurgery
#10
JOURNAL ARTICLE
Mina Lee, Eun Ji Lee, Rae On Kim, Jung-Min Pyun, Byung-Euk Joo, Kyum-Yil Kwon, Hakjae Roh, Moo-Young Ahn, Kyungbok Lee
OBJECTIVES: Although the systemic immune-inflammatory index (SII) has recently been correlated with stroke severity and functional outcome, the underlying pathogenesis remains largely unknown. The objective of this study was to explore whether SII could predict early neurologic deterioration (END) in different etiologies of acute ischemic stroke. MATERIALS AND METHODS: From January 2019 to December 2021, a total of 697 consecutive patients with acute ischemic stroke, admitted within 72 hours from stroke onset, were prospectively enrolled...
February 18, 2024: Clinical Neurology and Neurosurgery
#11
JOURNAL ARTICLE
Yi-Hsueh Lu, Lakshmi Mahajan, Hayeem L Rudy, Yufan Yan, Joseph A Ricci
BACKGROUND: There is an increasing prevalence of marijuana use in the general population yet clinical studies on marijuana's effect on surgical outcomes remain limited. Marijuana's effect on wound healing, venous thromboembolism due to endothelial inflammation, and bleeding due to inhibited platelet function have been cited based on animal models but have not been evaluated clinically in patients undergoing microsurgical reconstruction. METHODS: Retrospective chart review was performed on all patients who underwent abdominal-based free flap breast reconstruction in a single institute from August 2018 to December 2022...
February 27, 2024: Journal of Reconstructive Microsurgery
#12
JOURNAL ARTICLE
Ethan Schonfeld, Aaryan Shah, Thomas Michael Johnstone, Adrian Rodrigues, Garret K Morris, Martin N Stienen, Anand Veeravagu
INTRODUCTION: Cervical spine procedures represent a major proportion of all spine surgery. Mitigating the revision rate following cervical procedures requires careful patient selection. While complication risk has successfully been predicted, revision risk has proven more challenging. This is likely due to the absence of granular variables in claims databases. The objective of this study was to develop a state-of-the-art of revision prediction of cervical spine surgery using laboratory and operative variables...
February 24, 2024: World Neurosurgery
#13
JOURNAL ARTICLE
Rita Jebrin, Wasim S El Nekidy, Emna Abidi, Terrence Lee St John, Praveen Kesav, Syed I Hussain, Manal Abdelsalam, Luna Khaled, Divya Raj, Seby John
BACKGROUND: Data on P2Y12 inhibitors responsiveness from the middle east is scarce. We sought to investigate patient responsiveness to P2Y12 inhibitors within a cohort of major races that characterize the UAE population. The secondary objective was to assess risk factors for hyper and hypo-responsiveness in this population. METHODS: We conducted a cross-sectional study on adults who received either clopidogrel or ticagrelor treatments and had platelet responsiveness testing before undergoing neuro-endovascular interventions at our quaternary care hospital between March 2015 and April 2019...
February 7, 2024: Clinical Neurology and Neurosurgery
#14
JOURNAL ARTICLE
Birgit Coucke, Steven De Vleeschouwer, Johannes van Loon, Frank Van Calenbergh, Anaïs Van Hoylandt, Laura Van Gerven, Tom Theys
OBJECTIVE: CSF leakage is a major complication after cranial surgery, and although fibrin sealants are widely used for reinforcing dural closure, concerns exist regarding their safety, efficacy, and cost. Leukocyte- and platelet-rich fibrin (L-PRF), an autologous platelet concentrate, is readily available and inexpensive, making it a cost-effective alternative for commercially available fibrin sealants. This study aimed to demonstrate the noninferiority of L-PRF compared with commercially available fibrin sealants in preventing postoperative CSF leakage in supra- and infratentorial cranial surgery, with secondary outcomes focused on CSF leakage risk factors and adverse events...
February 23, 2024: Journal of Neurosurgery
#15
JOURNAL ARTICLE
Chun-Wei Ting, Tsung-Han Lee, Yu-Hua Huang
OBJECTIVE: Spontaneous intracerebral hemorrhage (ICH) poses a public health issue due to its elevated mortality rates. The International Normalized Ratio-platelet index (INR-Plt index) has recently been recognized as a predictive factor for liver disease progression. The potential of applying the INR-Plt index in forecasting ICH prognosis presents an intriguing subject. This study endeavors to examine the correlation between the INR-Plt index and hospital outcomes in patients with spontaneous supratentorial ICH...
February 19, 2024: World Neurosurgery
#16
JOURNAL ARTICLE
Karolina Kania, Mikołaj A Pawlak, Maria Forycka, Monika Wiłkość-Dębczyńska, Sławomir Michalak, Agnieszka Łukaszewska, Aleksandra Wyciszkiewicz, Aleksandra Wypych, Zbigniew Serafin, Justyna Marcinkowska, Wojciech Kozubski, Alicja Kalinowska-Łyszczarz
INTRODUCTION: Cognitive impairment occurs from the earliest stages of multiple sclerosis (MS) and progresses over time. The introduction of disease modifying therapies (DMTs) has changed the prognosis for MS patients, offering a potential opportunity for improvement in the cognitive arena as well. MATERIAL AND METHODS: 41 patients with relapsing-remitting multiple sclerosis (MS) were recruited to the study. Thirty patients were available for final follow-up and were included in the analysis...
February 7, 2024: Neurologia i Neurochirurgia Polska
#17
JOURNAL ARTICLE
Ilakyaa Rajakumar, T A Vidya, Krithika Ramachandran, Aamina Hussain, J Aarthi, M Poovitha, K Madhavan, J S Kumar
OBJECTIVE: Stroke is the cause of one in eight deaths and adds a dreadful burden of disability for the patients. Ischemic stroke is caused by a loss of blood supply to brain due to sudden occlusion of the arterial system, caused by an emboli or thrombus. Our aim was to correlate platelet indices, total cholesterol ratio, and various comorbidities with stroke. METHODS: A cross-sectional study was performed from 2020-2022 with 132 stroke patients admitted to the SRM Medical College Hospital and Research Center, India...
January 15, 2024: Clinical Neurology and Neurosurgery
#18
JOURNAL ARTICLE
Xian Wang, Yongfeng Zhao, Jian Zhao, Li Deng
Severe postoperative pneumonia can increase the risk of poor outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH). We aimed to explore the associations of preoperative or postoperative inflammatory markers calculated from blood cell counts with severe pneumonia. This retrospective study was conducted at the First Affiliated Hospital of Yangtze University from January 2019 to June 2023. The associations of neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), systemic immune inflammation index (SII), and systemic inflammation response index (SIRI) with severe pneumonia were analyzed...
January 26, 2024: Neurosurgical Review
#19
JOURNAL ARTICLE
Ali Bakhsh, Conor S Gillespie, George E Richardson, Mohammed A Mustafa, Christopher P Millward, Nasir Mirza, Michael D Jenkinson
PURPOSE: To investigate the association between perioperative peripheral blood inflammatory markers and seizures in patients who have undergone meningioma resection. MATERIALS AND METHODS: A single neurosurgery tertiary centre blood bank database was screened to extract pre-operative and post-operative white cell count (WCC), neutrophils, lymphocytes, monocytes, platelets and neutrophil-lymphocyte ratio (NLR) and derived NLR (dNLR). All patients who underwent resection of meningioma from 2012 to 2020 were eligible...
January 13, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
#20
Vsevolod Shurkhay, Brandon L King, Nikki J Acuff, James Neel, M Yashar S Kalani
Vertebral artery (VA) stenosis is a cause of vertebrobasilar insufficiency (VBI) and disabling posterior circulation stroke1 , accounting for up to 30% of all strokes.2 Although the natural history of VBI is not as well delineated as that of carotid stenosis, strokes in the basilar circulation can be more disabling than their anterior circulation counterparts. Stenosis exceeding 30% at the origin of the vertebral artery is associated with increased risk of stroke.3 The authors present a case of a female patient with significant peripheral vascular disease who presents with concerns for VBI...
January 5, 2024: World Neurosurgery
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