Yongping He, Qianxue Yu, Xiaoyu Ma, Diya Lv, Hui Wang, Weian Qiu, Xiao Fei Chen, Yang Jiao, Yue Liu
ETHNOPHARMACOLOGICAL RELEVANCE: Tanacetum parthenium (L.) Schultz-Bip, commonly known as feverfew, has been traditionally used to treat fever, migraines, rheumatoid arthritis, and cancer. Parthenolide (PTL), the main bioactive ingredient isolated from the shoots of feverfew, is a sesquiterpene lactone with anti-inflammatory and antitumor properties. Previous studies showed that PTL exerts anticancer activity in various cancers, including hepatoma, cholangiocarcinoma, acute myeloid leukemia, breast, prostate, and colorectal cancer...
March 19, 2024: Journal of Ethnopharmacology