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https://read.qxmd.com/read/30772981/-study-on-the-risk-factors-for-hemorrhagic-transformation-of-cerebellar-infarction-after-posterior-fossa-decompression-surgery
#1
Z J Xu, D F Yu, H Xu, G Z Zhou
Objective: To investigate the related risk factors for hemorrhagic transformation (HT) of cerebellar infarction after posterior fossa decompression surgery. Methods: A total of 91 patients with cerebellar infarction were treated by posterior fossa decompression surgery in Department of Neurosurgery of Jinhua Municipal Central Hospital from Jan 2010 to Jan 2018, were selected as study subjects. The HT group included 17 cases, while the Non-HT group included 74 cases. The clinical data of the two groups were analyzed retrospectively, the univariate and non-conditional lgistic regression analysis were performed to detect the relevant risk factors for hemorrhagic transformation of cerebellar infarction after posterior fossa decompression surgery...
January 29, 2019: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/30772976/-pla2g6-compound-complicated-mutation-in-an-atypical-neuroaxonal-dystrophy-pedigree
#2
L M Ma, J Zhao, Y Y Shi, Z Z Chen, Z X Ren, J W Zhang
Objective: To analyze the clinical presentation, imaging features, and the mutation of the pathogenic genes in a Chinese Han atypical neuroaxonal dystrophy pedigree. Methods: A family of atypical neuroaxonal dystrophy pedigree who came to Henan Provincal People's Hospital in July 2016 was included. Clinical presentation, imaging features of the pedigree were analyzed, and all exon gene detection of the proband was performed to capture the target variations, then verified by sanger sequence. Another 4 family members' and 100 normal healthy controls' gene sequence of the mutations were also verified...
January 29, 2019: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/30772972/-magnetic-resonance-imaging-study-of-endolymphatic-hydrops-based-on-3d-flair-sequence-after-single-dose-intravenous-gadolinium-injection
#3
Y Lin, Z Y Wang, Z R Zhang, X Zheng, Q H Chen, H J Wang, X P Hao, Y X Li, J F Xian, B T Yang
Objective: To investigate the visualization of endolymph in patients with otogenic vertigo by intravenous administration of single dose of gadolinium contrast agents and magnetic resonance three-dimensional fluid-attenuated inversion recovery sequence (3D-FLAIR MRI), and further assess the extent of endolymphatic hydrops. Methods: From Beijing Tongren Hospital of Capital Medical University between October 2017 and June 2018, 30 patients (16 males, 14 females) with unilateral otogenic vertigo were involved in this study, with the age of 30 to 68 years, mean age of (53±10) years...
January 29, 2019: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/30772952/circle-of-willis-variations-in-migraine-patients-with-ischemic-stroke
#4
Arend M Hamming, Marianne A A van Walderveen, Inge A Mulder, Irene C van der Schaaf, L Jaap Kappelle, Birgitta K Velthuis, Michel D Ferrari, Gisela M Terwindt, Marieke C Visser, Wouter Schonewille, Ale Algra, Marieke J H Wermer
OBJECTIVES: Migraine is a risk factor for stroke, which might be explained by a higher prevalence in anatomical variants in the circle of Willis (CoW). Here, we compared the presence of CoW variants in patients with stroke with and without migraine. MATERIALS AND METHODS: Participants were recruited from the prospective Dutch acute Stroke Study. All participants underwent CT angiography on admission. Lifetime migraine history was assessed with a screening questionnaire and confirmed by an interview based on International Classification of Headache Disorders criteria...
February 16, 2019: Brain and Behavior
https://read.qxmd.com/read/30772884/-surgical-repair-of-stanford-type-a-acute-aortic-dissection-associated-with-anomalous-retroaortic-left-brachiocephalic-vein-report-of-a-case
#5
Takayuki Nishimoto, Yukihiro Bonkohara, Hironori Murakami
Anomalous retroaortic left brachiocephalic vein( ARLBV) is a rare vascular abnormaly, usually asossiated with congenital heart diseases. We present a very rare case of Stanford type A acute aortic dissection associated with ARLBV. A 70-year-old man was referred to our hospital complaining of worsening back pain and chest pain. Computed tomographic angiogram showed Stanford type A acute aortic dissection from the ascending aorta to the distal abdominal aorta. Furthermore, systemic venous anomalies were revealed...
February 2019: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://read.qxmd.com/read/30772698/impact-of-acute-sleep-restriction-on-cerebral-glucose-metabolism-during-recovery-non-rapid-eye-movement-sleep-among-individuals-with-primary-insomnia-and-good-sleeper-controls
#6
Daniel B Kay, Helmet T Karim, Brant P Hasler, Jeffrey A James, Anne Germain, Martica H Hall, Peter L Franzen, Julie C Price, Eric A Nofzinger, Daniel J Buysse
BACKGROUND: Restricting time in bed improves insomnia symptoms, but the neural mechanisms for this effect are unknown. Total and partial acute sleep restriction may be useful paradigms for elucidating these effects. We examined the impact of acute sleep restriction on cerebral glucose metabolism during non-rapid eye movement (NREM) sleep in individuals with primary insomnia (n = 17) and good sleep (n = 19). METHODS: Participants underwent [18 F]fluorodeoxyglucose positron emission tomography scans during baseline and recovery NREM sleep following one night of partial or total sleep restriction...
January 4, 2019: Sleep Medicine
https://read.qxmd.com/read/30772522/curation-and-bioinformatic-analysis-of-strabismus-genes-supports-functional-heterogeneity-and-proposes-candidate-genes-with-connections-to-rasopathies
#7
Xin Cynthia Ye, Robin van der Lee, Wyeth W Wasserman
Strabismus refers to the misalignment of the eyes and occurs in 2-4% of individuals. The low-resolution label "strabismus" covers a range of heterogeneous defects, which makes it challenging to unravel this condition. Consequently a coherent understanding of the causes is lacking. Here, we attempt to gain a better understanding of the underlying genetics by combining gene curation, diverse bioinformatic analyses (including gene ontology, pathway mapping, expression and network-based methods) and literature review...
February 14, 2019: Gene
https://read.qxmd.com/read/30772505/association-between-mri-findings-and-back-pain-after-osteoporotic-vertebral-fractures-a-multicenter-prospective-cohort-study
#8
Sayed Abdullah Ahmadi, Shinji Takahashi, Masatoshi Hoshino, Kazushi Takayama, Ryuichi Sasaoka, Tadao Tsujio, Hiroyuki Yasuda, Fumiaki Kanematsu, Hiroshi Kono, Hiromitsu Toyoda, Hiroaki Nakamura
BACKGROUND CONTEXT: Osteoprotic vertebral fractures(OFV) are common in elderly people. The association between back pain due to OVF with MRI signal change is unclear. In this study we hypothesized that MRI findingswould be a predictive factor for back pain measured by VAS at 6 months follow-up. PURPOSE: The aim was to study the magnetic resonance imaging (MRI) findings that predict back pain after osteoporotic vertebral fractures (OVF) and the association between radiological findings and scores of back pain...
February 14, 2019: Spine Journal: Official Journal of the North American Spine Society
https://read.qxmd.com/read/30772405/response-inhibition-in-borderline-personality-disorder-neural-and-behavioral-correlates
#9
Jacobo Albert, Sara López-Martín, Rocío Arza, Nerea Palomares, Sandra Hoyos, Luis Carretié, Marina Díaz-Marsá, José Luis Carrasco
Although response inhibition is thought to be important in borderline personality disorder (BPD), little is known about its neurophysiological basis. This study aimed to provide insight into this issue by capitalizaing on the the high temporal resolution of electroencephalography and information provided by source localization methods. To this end, twenty unmedicated patients with BPD and 20 healthy control subjects performed a modified go/no-go task designed to better isolate the brain activity specifically associated with response inhibition...
February 14, 2019: Biological Psychology
https://read.qxmd.com/read/30772349/-intraocular-oxygen-and-antioxidant-status-new-insights-on-the-effect-of-vitrectomy-and-glaucoma-pathogenesis
#10
Carla J Siegfried, Ying-Bo Shui
PURPOSE: To investigate correlations of oxygen (pO2 ) in the ocular anterior segment of human eyes and aqueous humor antioxidant levels of ascorbate (AsA) and total reactive antioxidant potential (TRAP) with glaucoma and vitreous status. METHODS: This prospective, cross-sectional study stratified patients (n=288 eyes) by lens and vitreous status and presence of primary open angle glaucoma for statistical analyses. Intraocular pO2 measurements with a fiberoptic probe were made in patients at the beginning of planned glaucoma and/or cataract surgery...
February 14, 2019: American Journal of Ophthalmology
https://read.qxmd.com/read/30772345/brillouin-spectroscopy-of-normal-and-keratoconus-corneas
#11
Theo G Seiler, Peng Shao, Amira Eltony, Theo Seiler, Seok-Hyun Yun
PURPOSE: To investigate the age-dependence of Brillouin spectroscopy of the cornea and to compare normal and keratoconus corneas. DESIGN: Retrospective case-control study STUDY POPULATION: Healthy patients and patients suffering from keratoconus seen at the Institut für Refraktive und Ophthalmo-Chirurgie (IROC) between December 2016 and March 2017. METHODS: Brillouin frequency shifts of patients of 2 different groups were examined with Brillouin spectroscopy perpendicular to the corneal surface...
February 14, 2019: American Journal of Ophthalmology
https://read.qxmd.com/read/30772183/clinical-factors-associated-with-successful-meniscal-root-repairs-a-systematic-review
#12
Eric X Jiang, Moneer M Abouljoud, Joshua S Everhart, Alex C DiBartola, Christopher C Kaeding, Robert A Magnussen, David C Flanigan
PURPOSE: To systematically review the literature to determine what clinical factors influence patient outcomes after meniscal root repairs. METHODS: A systematic review of multiple databases was performed. The inclusion criteria included English language, studies evaluating clinical and/or radiographic factors related to meniscal root repair outcomes, medial or lateral posterior root repairs, and human studies. The exclusion criteria included meniscectomy studies, meniscal body studies, technique descriptions, studies reporting only failure rate of meniscal repairs, multiligament repairs, abstracts, controlled laboratory studies, meta-analyses, and systematic reviews...
February 13, 2019: Knee
https://read.qxmd.com/read/30772173/catching-condyle-endoscopic-assisted-transoral-open-reduction-and-rigid-fixation-of-condylar-process-fractures-using-an-auto-reposition-and-fixation-osteosynthesis-plate
#13
Philipp Poxleitner, Pit Jacob Voss, David Steybe, Stefan Schlager, Steffen Schwarz, Marc Anton Fuessinger, Rainer Schmelzeisen, Marc Metzger
INTRODUCTION: Fractures of the mandibular condyle are reported to account for 9 %-45 % of all mandibular fractures. There has been a long lasting controversy on the superiority of different treatment options with endoscopic-assisted transoral approaches gaining increasing attention in recent years. In this article, we report the application of a newly developed osteosynthesis plate for an auto reposition, reconstruction and rigid fixation of condylar process fractures. MATERIAL AND METHODS: We present 6 cases of uni- or bilateral fractures of the condylar process treated with a transoral open reduction and rigid fixation using an auto reposition plate...
February 4, 2019: Journal of Cranio-maxillo-facial Surgery
https://read.qxmd.com/read/30772142/assessment-of-dose-to-functional-sub-structures-in-the-lower-urinary-tract-in-locally-advanced-cervical-cancer-radiotherapy
#14
S Spampinato, L Fokdal, E Marinovskij, S Axelsen, E M Pedersen, R Pötter, J C Lindegaard, K Tanderup
PURPOSE: To provide an analysis of dose distribution in sub-structures that could be responsible for urinary toxicity after Image-Guided Adaptive BrachyTherapy (IGABT) in Locally Advanced Cervical Cancer (LACC). METHODS: 105 LACC patients treated with radiochemotherapy and IGABT were selected. Sub-structures (bladder wall, trigone, bladder neck, urethra) were contoured on IGABT-planning MRIs. D2cm3 and D0.1cm3 , ICRU Bladder-Point (ICRU BP) and Posterior-Inferior Border of Symphysis points (PIBS, PIBS + 2 cm, PIBS - 2 cm) doses were extracted...
February 13, 2019: Physica Medica: PM
https://read.qxmd.com/read/30772096/a-case-of-confusional-migraine-with-transient-increased-cerebral-blood-flow
#15
Emiko Momoki, Tatsuo Fuchigami, Yuki Kasuga, Kaori Kimura, Wakako Ishii, Ayumi Fukuda, Yukihiko Fujita, Ichiro Morioka
BACKGROUND: Confusional migraine is a rare type of migraine presenting as an acute confusional state. However, the mechanism of this confusional state remains unclear. SUBJECT AND METHODS: We examined an 11-year-old girl with confusional migraine, using electroencephalography, brain magnetic resonance imaging, cerebrovascular magnetic resonance angiography, and single-photon emission computed tomography to investigate cerebral blood flow changes. RESULTS: Our findings revealed vessel narrowing in the left middle and posterior cerebral artery territory, indicating vasospasm and suggesting that the confusion was caused by hypoperfusion...
February 13, 2019: Brain & Development
https://read.qxmd.com/read/30772081/the-spatial-structure-of-neural-encoding-in-mouse-posterior-cortex-during-navigation
#16
Matthias Minderer, Kristen D Brown, Christopher D Harvey
Navigation engages many cortical areas, including visual, parietal, and retrosplenial cortices. These regions have been mapped anatomically and with sensory stimuli and studied individually during behavior. Here, we investigated how behaviorally driven neural activity is distributed and combined across these regions. We performed dense sampling of single-neuron activity across the mouse posterior cortex and developed unbiased methods to relate neural activity to behavior and anatomical space. Most parts of the posterior cortex encoded most behavior-related features...
February 11, 2019: Neuron
https://read.qxmd.com/read/30772067/altered-dynamic-global-signal-topography-in-antipsychotic-naive-adolescents-with-early-onset-schizophrenia
#17
Xiao Wang, Wei Liao, Shaoqiang Han, Jiao Li, Yan Zhang, Jingping Zhao, Huafu Chen
Schizophrenia (SCZ) is a severe neuropsychiatric disease associated with dysfunction of brain regions and networks. Recent, functional magnetic resonance imaging (fMRI) studies have determined that the global signal (GS) is an important source of the local neuronal activity. However, the dynamics of this effect in SCZ remains unknown. To address this issue, 39 drug-naive patients with early-onset schizophrenia (EOS) and 31 age-, gender- and education-matched healthy controls underwent resting-state fMRI scans...
February 14, 2019: Schizophrenia Research
https://read.qxmd.com/read/30771894/risk-factors-of-clinical-mastitis-and-antimicrobial-susceptibility-test-results-of-mastitis-milk-from-dairy-cattle-in-western-thailand-bayesian-network-analysis
#18
Wantida Horpiencharoen, Sukanya Thongratsakul, Chaithep Poolkhet
Using Bayesian network analysis, this cross-sectional study aimed to identify the conditional probability among dairy farm practices, cow characteristics, bacteriological culture results, and antimicrobial susceptibility test results of milk from dairy cows with clinical mastitis in western Thailand. Data associated with risk factors and clinical signs were collected using a structured questionnaire that was administered to 34 small dairy holders. In total, 100 quarters of milk samples from 100 cows were used for Bayesian network analysis...
March 1, 2019: Preventive Veterinary Medicine
https://read.qxmd.com/read/30771782/development-of-a-novel-frameless-skull-mounted-ball-joint-guide-array-for-use-in-image-guided-neurosurgery
#19
Vivek Sudhakar, Amin Mahmoodi, John R Bringas, Jerusha Naidoo, Adrian Kells, Lluis Samaranch, Massimo S Fiandaca, Krystof S Bankiewicz
OBJECTIVESuccessful convection-enhanced delivery of therapeutic agents to subcortical brain structures requires accurate cannula placement. Stereotactic guiding devices have been developed to accurately target brain nuclei. However, technologies remain limited by a lack of MRI compatibility, or by devices' size, making them suboptimal for direct gene delivery to brain parenchyma. The goal of this study was to validate the accuracy of a novel frameless skull-mounted ball-joint guide array (BJGA) in targeting the nonhuman primate (NHP) brain...
February 15, 2019: Journal of Neurosurgery
https://read.qxmd.com/read/30771779/somatotopic-organization-of-the-human-spinothalamic-tract-in-vivo-computed-tomography-guided-mapping-in-awake-patients-undergoing-cordotomy
#20
C Michael Honey, Zurab Ivanishvili, Christopher R Honey, Manraj K S Heran
OBJECTIVEThe location of the human spinothalamic tract (STT) in the anterolateral spinal cord has been known for more than a century. The exact nature of the neuronal fiber lamination within the STT, however, remains controversial. After correlating in vivo macrostimulation-induced pain/temperature sensation during percutaneous cervical cordotomy with simultaneous CT imaging of the electrode tip location, the authors present a modern description of the somatotopy of the human cervical STT.METHODSTwenty patients underwent CT-guided percutaneous cervical cordotomy to alleviate contralateral medication-refractory cancer pain...
February 15, 2019: Journal of Neurosurgery. Spine
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