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Colon emergency

Elio Treppiedi, Lorenzo Cocchi, Giuseppe Zimmitti, Alberto Manzoni, Valeria Seletti, Alessandra Bizzotto, Cristiano Spada, Marco Garatti, Edoardo Rosso
Adult intussusception of the bowel is a rare clinical entity, and its management remains debated. The timing of treatment is not yet standardised, and no guidelines exist. We report a case of an 83-year-old woman presenting to the emergency department of our hospital with a history of increasing abdominal pain in the right iliac fossa. A contrast-enhanced computed tomography scan showed the presence of a large ileocolic intussusception with evidence of the terminal ileus invaginated within the right colon and the ileocolic vessels dragged and trapped into the intussusception...
February 18, 2019: Journal of Minimal Access Surgery
Arnaud Roussel, Nellie Della Schiava, Raphaël Coscas, Quentin Pellenc, Tarek Boudjelit, Olivier Goëau-Brissonnière, Olivier Corcos, Patrick Lermusiaux, Marc Coggia, Yves Castier
OBJECTIVE: Acute mesenteric ischemia (AMI) is an emergent event with a high mortality rate; survivors have high rates of intestinal failure. Restoration of blood flow using endovascular or surgical revascularization is associated with better outcome in terms of survival rate and intestinal resection. Retrograde open mesenteric stenting (ROMS), which is a hybrid technique, combines two benefits: prompt blood flow restoration with an endovascular approach and inspection and resection of the small bowel...
February 15, 2019: Journal of Vascular Surgery
Tomohiro Muronoi, Akihiko Kidani, Eiji Hira, Kayo Takeda, Shunsuke Kuramoto, Kazuyuki Oka, Yoshihide Shimojo, Hiroaki Watanabe
INTRODUCTION: Mediastinal and subcutaneous emphysema usually result from spontaneous rupture of the alveolar wall. We present an extremely rare case of massive mediastinal, retroperitoneal, and subcutaneous emphysema due to the penetration of the colon into the mesentery. PRESENTATION OF CASE: A 57-year-old man presented to our institution with a history of chest pain. The patient's medical history included malignant rheumatoid arthritis during the use of steroids and an immunosuppressive agent...
February 10, 2019: International Journal of Surgery Case Reports
Noboru Oyachi, Takaki Emura, Fuminori Numano, Tomoko Tando, Tomohiro Saito, Yusuke Goto
BACKGROUND: Non-occlusive mesenteric ischemia (NOMI) is a rare and severe pathological condition that can cause intestinal necrosis without mechanical obstruction of the mesenteric artery. NOMI often develops during the treatment of severe disease in elderly patients and mostly occurs in the intestine supplied by the superior mesenteric artery (SMA). We experienced a 12-year-old patient with NOMI that was segmentally localized in the ascending colon and rectum during encephalitis treatment...
February 15, 2019: Surgical Case Reports
Joost Hopman, Corianne Meijer, Nikki Kenters, Jordy P M Coolen, Mohammad R Ghamati, Shaheen Mehtar, Reinout van Crevel, Wim J Morshuis, Ad F T M Verhagen, Michel M van den Heuvel, Andreas Voss, Heiman F L Wertheim
Importance: Resistance of gram-negative bacilli to carbapenems is rapidly emerging worldwide. In 2016, the World Health Organization defined the hospital-built environment as a core component of infection prevention and control programs. The hospital-built environment has recently been reported as a source for outbreaks and sporadic transmission events of carbapenemase-producing gram-negative bacilli from the environment to patients. Objective: To assess risk after the identification of an unexpected, severe, and lethal hospital-acquired infection caused by carbapenemase-producing Pseudomonas aeruginosa in a carbapenemase-low endemic setting...
February 1, 2019: JAMA network open
Tawfik Khoury, Saleh Daher, Muhammad Massarwa, David Hakimian, Ariel A Benson, Elez Viener, Raymond Farah, Amir Mari, Wadi Hazou, Anas Kadah, Wisam Sbeit, Mahmud Mahamid, Eran Israeli
BACKGROUND AND AIMS: A majority of acutely-ill Crohn's disease (CD) patients who present to Emergency Department (ED) will undergo an abdominal CT to rule out disease complications. We aimed to generate a simple non-invasive scoring model to predict the presence of an intra-abdominal abscess in CD patients in the ED. METHODS: We performed a retrospective case control study at four Israeli hospitals from January-1 st-2010 to May-30 th-2018. Inclusion criteria included patients with an established diagnosis of CD that had cross-sectional abdominal imaging performed...
February 14, 2019: Journal of Crohn's & Colitis
Savas Bayrak, Cihad Tatar, Erdem Kinaci, Ekrem Cakar, Sukru Colak, Mert Mahsuni Sevinc, Hasan Bektas
Introduction: Stent treatment can be applied to avoid surgery in surgically risky patients or to turn a high-risk emergency operation into a lower-risk elective operation and save time. Aim: In this study, the techniques, clinical efficacy, safety and complications of endoscopic stents applied in emergency conditions were evaluated in patients with acute mechanical intestinal obstruction (AMIO) due to colorectal cancer. Material and methods: Between 2013 and 2015, 23 patients with an average age of 69...
January 2019: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
Takeshi Hijikawa, Hiroaki Kitade, Hidesuke Yanagida, Masanori Yamada, Shuhei Maruyama, Fukuki Saito, Yasushi Nakamori, Kazuhiko Yoshioka
A70 -year-old man with a diagnosis of panperitonitis caused by colon perforation due to invasion of gallbladder cancer was transferred to our hospital. The next day, an emergency operation was performed. During laparotomy, the ascending colon was perforated; therefore, ileocecal resection was performed. Six hours after the operation, the stoma became ischemic with marked abdominal distention. The intra-abdominal pressure increased to 28 mmHg, and the patient was diagnosed as having abdominal compartment syndrome(ACS)...
January 2019: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Mitsuru Watanabe, Tetsuo Sumi, Ryutaro Udou, Masaya Enomoto, Takaaki Matsudo, Shingo Tachibana, Akihiro Mimuro, Kenji Katsumata, Akihiko Tsuchida
A 61-year-old man with a diagnosis of rectal cancer underwent assisted laparoscopic rectal amputation. Recurrence occurred, and treatment with FOLFIRI plus bevacizumab was initiated at our department. After 12 treatment courses, he developed abdominal pain at home. Emergency surgery was performed for the stoma perforation. We confirmed the diverticular perforation in the resected specimen. In our case, we found a para-stoma hernia and considered it to be the cause of perforation together with bevacizumab administration...
January 2019: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Julian R Garneau, Claire Nour Abou Chakra, Louis-Charles Fortier, Annie-Claude Labbé, Andrew E Simor, Wayne Gold, Matthew Muller, Allison McGeer, Jeff Powis, Kevin Katz, Jacques Pépin, Louis Valiquette
The epidemiology of Clostridioides difficile infection (CDI) has drastically changed since the emergence of the epidemic strain BI/NAP1/027, also known as ribotype 027 (R027). However, the relationship between the infecting C. difficile strain and clinical outcomes is still debated. We hypothesized that certain subpopulations of R027 isolates could be associated with unfavorable outcomes. We applied high-resolution multilocus variable-number tandem-repeat analysis (MLVA) to characterize C. difficile R027 isolates collected from confirmed CDI patients recruited across 10 Canadian hospitals from 2005 to 2008...
February 13, 2019: Journal of Clinical Microbiology
Suresh Garudadri, Prescott G Woodruff
Chronic obstructive pulmonary disease (COPD) is now well recognized to be a phenotypically heterogeneous disease, and this heterogeneity is underpinned by biological heterogeneity. An "endotype" is a group of patients who share the same observed characteristic(s) because of shared underlying biology, and the "endotype" concept has emerged as one way of bringing order to this phenotypic heterogeneity by focusing on its biological underpinnings. In principle, biomarkers can help identify endotypes and mark these specific groups of patients as suitable candidates for targeted biological therapies...
December 2018: Annals of the American Thoracic Society
J Reibetanz, C T Germer
No abstract text is available yet for this article.
February 13, 2019: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Niraj Vora, Ram Kalagiri, Lea H Mallett, Jin Ho Oh, Umaima Wajid, Saef Munir, Natalie Colon, Venkata Nakta Raju, Madhava R Beeram, M Nasir Uddin
Importance: Pregnancy is getting more and more complex due to increasing number of complications that may affect fetal outcomes. The introduction of newer "proteomics and metabolomics" technologies in the field of obstetrics and gynecology may allow physicians to identify possible associated etiologies that affect the mother during pregnancy and lead to associated complications affecting the offspring. Objective: The principal objective of this review article is to provide a comprehensive evaluation of the use of proteomics and metabolomics in complicated pregnancies...
February 2019: Obstetrical & Gynecological Survey
Jianhua Dou, Jinrong Zeng, Kathy Wu, Wenbin Tan, Lihua Gao, Jianyun Lu
Atopic dermatitis (AD) is a chronic, non-contagious, inflammatory skin disorder characterized by relapsing eczematous lesions. Its pathogenesis remains incompletely understood. The current evidence has emerged to show that skin and gut microbiome play critical roles in the pathogenesis and progression of AD. Skin mircrobiome mainly refers to skin commensal organisms that promote normal immune system functions and prevent the colonization of pathogens; while gut microbiome can modulate immunologic, metabolic and neuroendocrine functions...
February 8, 2019: International Immunopharmacology
Aylin Hande Gökçe
Gastrointestinal stromal tumors (GISTs) are among the rare tumors of gastrointestinal (GI) tract. GISTs occur respectively in the stomach, small intestines, colon and rectum, omentum and mesentery, esophagus, retroperitoneal space, and abdominal cavity. However, they may occur anywhere along the GI tract. Typically, these tumors generally do not cause symptoms; however symptomatic patients may show stomach pain, GI bleeding, and palpable abdominal masses. These patients usually undergo surgery for obstruction symptoms or some other diagnosis...
January 2019: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
Fabian Grass, David Martin, Estelle Moulin, Dieter Hahnloser, Nicolas Demartines, Martin Hübner
BACKGROUND: The present study aimed to analyze risk factors and management strategies for organ space infections (OSI) specifically after colonic resections. METHODS: This was a retrospective analysis of all consecutive colonic resections performed between February 2012 and October 2017 in a single-center quality-improvement project. All OSIs were assessed prospectively by an independent national surveillance program ( ) and classified according to the U...
February 11, 2019: Surgical Infections
Cullen K McCarthy, Paul K McGaha, Noah S Rozich, Nathaniel A Yokell, Jason S Lees, William L Berry
Intestinal anastomoses are commonly performed in both elective and emergent operations. Even so, anastomotic leaks are a highly feared complications of colonic surgeries and can occur in up to 26% of surgical anastomoses, with mortality being up to 39% for patients with such a leak. Currently, there remains a paucity of data detailing the cellular mechanisms of anastomotic healing. Devising preventative strategies and treatment modalities for anastomotic leak could be greatly potentiated by a better understanding of appropriate anastomotic healing...
January 17, 2019: Journal of Visualized Experiments: JoVE
Santiago Olguín Joseau, Natalia Paola Bollati, Santiago Reimondez, Franco Signorini, Alejandro Mario Rossini, Pablo Sergio Maldonado, Federico Moser, Lucio Ricardo Obeide, Alvaro Alcaraz, Juan Pablo Caeiro
BACKGROUND: Surgical site infection (SSI) is the most common nosocomial infection in surgical patients with an incidence that varies between 5-30%. OBJECTIVE: Identify the risk factors for SSI in colonic surgery in our population. The secondary aims are to determine the incidence and type of SSI, as well as the incidence of an anastomotic leakage (AL). METHODS: Case-control study of patients undergoing colectomy between 2010-2014 at the Hospital Privado Univeristario de Córdoba and Hospital Raúl Ferreyra...
November 14, 2018: Revista de la Facultad de Ciencias Médicas
Nerella Sridhar Goud, S Mahammad Ghouse, Jatoth Vishnu, Jakkula Pranay, Ravi Alvala, Venu Talla, Insaf A Qureshi, Mallika Alvala
BACKGROUND: Human Galectin-1, protein of lectin family showing affinity towards β-galactosides has emerged as critical regulator of tumor progression and metastasis, by modulating diverse biological events including homotypic cell aggregation, migration, apoptosis, angiogenesis and immune escape. Therefore, galectin-1 inhibitors might represent novel therapeutic agents for cancer. METHODS: A new series of heterocyclic imines linked coumarin-thiazole hybrids (6a-6r) has been synthesized and evaluated for their cytotoxic potential against a panel of six human cancer cell lines namely, lung (A549), prostate (DU-145), breast (MCF-7 & MDA-MB-231), colon (HCT-15 & HT-29) using MTT assay...
February 7, 2019: Anti-cancer Agents in Medicinal Chemistry
Cristina Renzi, Georgios Lyratzopoulos, Willie Hamilton, Bernard Rachet
OBJECTIVES: To identify opportunities for reducing emergency colon cancer diagnoses, we evaluated symptoms and benign diagnoses recorded before emergency presentations (EP). METHODS: Cohort of 5,745 colon cancers diagnosed in England 2005-2010, with individually linked cancer registry and primary care data for the 5-year pre-diagnostic period. RESULTS: Colon cancer was diagnosed following EP in 34% of women and 30% of men. Among emergency presenters, 20% of women and 15% of men (p = 0...
February 8, 2019: European Journal of Cancer Care
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