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Kaitlin Benedict

Orion Z McCotter, Kaitlin Benedict, David M Engelthaler, Ken Komatsu, Kimberley D Lucas, Janet C Mohle-Boetani, Hanna Oltean, Duc Vugia, Tom M Chiller, Gail L Sondermeyer Cooksey, Alyssa Nguyen, Chandler C Roe, Charlotte Wheeler, Rebecca Sunenshine
The incidence of reported coccidioidomycosis in the past two decades has increased greatly; monitoring its changing epidemiology is essential for understanding its burden on patients and the healthcare system and for identifying opportunities for prevention and education. We provide an update on recent coccidioidomycosis trends and public health efforts nationally and in Arizona, California, and Washington State. In Arizona, enhanced surveillance shows that coccidioidomycosis continues to be associated with substantial morbidity...
February 1, 2019: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
Jeremy McAdam, Kaitlin McGinnis, Rian Ory, Kaelin Young, Andrew D Frugé, Michael Roberts, JoEllen Sefton
BACKGROUND: Adequate dietary intake is important for promoting adaptation and prevention of musculoskeletal injury in response to large volumes of physical training such as Army Initial Entry Training (IET). The purpose of this study was to evaluate training volume and dietary intake and estimate energy balance in Army IET soldiers. METHODS: Dietary intake was assessed by collecting diet logs for three meals on each of three, non-consecutive days during the first week of IET...
November 28, 2018: Journal of the International Society of Sports Nutrition
Robert McDonald, Elizabeth Dufort, Brendan R Jackson, Ellis H Tobin, Alexandra Newman, Kaitlin Benedict, Debra Blog
No abstract text is available yet for this article.
September 28, 2018: MMWR. Morbidity and Mortality Weekly Report
Sharon Tsay, Sabrina R Williams, Kaitlin Benedict, Zintars Beldavs, Monica Farley, Lee Harrison, William Schaffner, Ghinwa Dumyati, Anna Blackstock, Alice Guh, Snigdha Vallabhaneni
Candidemia and Clostridium difficile infection (CDI) are important healthcare-associated infections that share certain risk factors. We sought to describe candidemia-CDI coinfection using population-based surveillance data. We found that nearly one in ten patients with candidemia had CDI coinfection.
July 27, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Kaitlin Benedict, Malia Ireland, Meghan P Weinberg, Randon J Gruninger, Jenna Weigand, Lei Chen, Katharine Perez-Lockett, Catherine Bledsoe, Lynn Denny, Katie Cibulskas, Suzanne Gibbons-Burgener, Anna Kocharian, Emilio DeBess, Tracy K Miller, Alicia Lepp, Laura Cronquist, Kimberly Warren, Jose Antonio Serrano, Cody Loveland, George Turabelidze, Orion McCotter, Brendan R Jackson
Although coccidioidomycosis in Arizona and California has been well-characterized, much remains unknown about its epidemiology in states where it is not highly endemic. We conducted enhanced surveillance in 14 such states in 2016 by identifying cases according to the Council of State and Territorial Epidemiologists case definition and interviewing patients about their demographic characteristics, clinical features, and exposures. Among 186 patients, median time from seeking healthcare to diagnosis was 38 days (range 1-1,654 days); 70% had another condition diagnosed before coccidioidomycosis testing occurred (of whom 83% were prescribed antibacterial medications); 43% were hospitalized; and 29% had culture-positive coccidioidomycosis...
July 2018: Emerging Infectious Diseases
Sara Y Tartof, Kaitlin Benedict, Fagen Xie, Gunter K Rieg, Kalvin C Yu, Richard Contreras, Jonathan Truong, Kimberlee Fong, Hung Fu Tseng, Steven J Jacobsen, Rajal K Mody
We conducted a cohort study to identify characteristics associated with testing for, and testing positive for, coccidioidomycosis among patients with community-acquired pneumonia in southern California, USA. Limited and delayed testing probably leads to underdiagnosis among non-Hispanic black, Filipino, or Hispanic patients and among high-risk groups, including persons in whom antimicrobial drug therapy has failed.
April 2018: Emerging Infectious Diseases
Kaitlin Benedict, Monika Roy, Sarah Kabbani, Evan J Anderson, Monica M Farley, Sasha Harb, Lee H Harrison, Lindsay Bonner, Vijitha Lahanda Wadu, Kaytlyn Marceaux, Rosemary Hollick, Zintar G Beldavs, Alexia Y Zhang, William Schaffner, Caroline R Graber, Gordana Derado, Tom M Chiller, Shawn R Lockhart, Snigdha Vallabhaneni
Introduction: Candida is a leading cause of healthcare-associated bloodstream infections in the United States. Infants and children have unique risk factors for candidemia, and the Candida species distribution in this group is different that among adults; however, candidemia epidemiology in this population has not been described recently. Methods: We conducted active population-based candidemia surveillance in 4 US metropolitan areas between 2009 and 2015. We calculated incidences among neonates (0-30 days old), infants (0-364 days old), and noninfant children (1-19 years old), documented their clinical features and antifungal drug resistance...
August 17, 2018: Journal of the Pediatric Infectious Diseases Society
Robin K Avery, Fernanda P Silveira, Kaitlin Benedict, Angela A Cleveland, Carol A Kauffman, Mindy G Schuster, Erik R Dubberke, Shahid Husain, David L Paterson, Tom Chiller, Peter Pappas
BACKGROUND: Most studies of post-transplant CMV infection have focused on either solid organ or hematopoietic cell transplant (HCT) recipients. A large prospective cohort study involving both lung and HCT recipients provided an opportunity to compare the epidemiology and outcomes of CMV infections in these 2 groups. METHODS: Patients were followed up for 30 months in a 6-center prospective cohort study. Data on demographics, CMV infections, tissue-invasive disease, recurrences, rejection, and immunosuppression were recorded...
June 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
Michael Freedman, Brendan R Jackson, Orion McCotter, Kaitlin Benedict
Coccidioidomycosis causes substantial illness and death in the United States each year. Although most cases are sporadic, outbreaks provide insight into the clinical and environmental features of coccidioidomycosis, high-risk activities, and the geographic range of Coccidioides fungi. We identified reports published in English of 47 coccidioidomycosis outbreaks worldwide that resulted in 1,464 cases during 1940-2015. Most (85%) outbreaks were associated with environmental exposures; the 2 largest outbreaks resulted from an earthquake and a large dust storm...
March 2018: Emerging Infectious Diseases
Paige A Armstrong, Brendan R Jackson, Dirk Haselow, Virgie Fields, Malia Ireland, Connie Austin, Kimberly Signs, Veronica Fialkowski, Reema Patel, Peggy Ellis, Peter C Iwen, Caitlin Pedati, Suzanne Gibbons-Burgener, Jannifer Anderson, Thomas Dobbs, Sherri Davidson, Mary McIntyre, Kimberly Warren, Joanne Midla, Nhiem Luong, Kaitlin Benedict
Histoplasmosis is one of the most common mycoses endemic to the United States, but it was reportable in only 10 states during 2016, when a national case definition was approved. To better characterize the epidemiologic features of histoplasmosis, we analyzed deidentified surveillance data for 2011-2014 from the following 12 states: Alabama, Arkansas, Delaware, Illinois, Indiana, Kentucky, Michigan, Minnesota, Mississippi, Nebraska, Pennsylvania, and Wisconsin. We examined epidemiologic and laboratory features and calculated state-specific annual and county-specific mean annual incidence rates...
March 2018: Emerging Infectious Diseases
Gail Sondermeyer Cooksey, Alyssa Nguyen, Kirsten Knutson, Farzaneh Tabnak, Kaitlin Benedict, Orion McCotter, Seema Jain, Duc Vugia
Coccidioidomycosis, or Valley Fever, is an infectious disease caused by inhalation of Coccidioides spp. spores (1). This soil-dwelling fungus is endemic in the southwestern United States, with most (97%) U.S. cases reported from Arizona and California (1,2). Following an incubation period of 1-3 weeks, symptomatic patients most often experience self-limited, influenza-like symptoms, but coccidioidomycosis also can lead to severe pulmonary disease and to rare cases of disseminated disease, including meningitis (1)...
August 11, 2017: MMWR. Morbidity and Mortality Weekly Report
Kaitlin Benedict, Malcolm Richardson, Snigdha Vallabhaneni, Brendan R Jackson, Tom Chiller
Several high-profile outbreaks have drawn attention to invasive fungal infections (IFIs) as an increasingly important public health problem. IFI outbreaks are caused by many different fungal pathogens and are associated with numerous settings and sources. In the community, IFI outbreaks often occur among people without predisposing medical conditions and are frequently precipitated by environmental disruption. Health-care-associated IFI outbreaks have been linked to suboptimal hospital environmental conditions, transmission via health-care workers' hands, contaminated medical products, and transplantation of infected organs...
December 2017: Lancet Infectious Diseases
Jennifer Shriber, Kathryn C Conlon, Kaitlin Benedict, Orion Z McCotter, Jesse E Bell
Coccidioidomycosis is a fungal infection endemic to the southwestern United States, particularly Arizona and California. Its incidence has increased, potentially due in part to the effects of changing climatic variables on fungal growth and spore dissemination. This study aims to quantify the county-level vulnerability to coccidioidomycosis in Arizona and California and to assess the relationships between population vulnerability and climate variability. The variables representing exposure, sensitivity, and adaptive capacity were combined to calculate county level vulnerability indices...
June 23, 2017: International Journal of Environmental Research and Public Health
Mindy G Schuster, Angela A Cleveland, Erik R Dubberke, Carol A Kauffman, Robin K Avery, Shahid Husain, David L Paterson, Fernanda P Silveira, Tom M Chiller, Kaitlin Benedict, Kathleen Murphy, Peter G Pappas
BACKGROUND: Infection is a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). Our object was to better define the epidemiology and outcomes of infections after HCT. METHODS: This was a prospective, multicenter cohort study of HCT recipients and conducted from 2006 to 2011. The study included 4 US transplant centers and 444 HCT recipients. Data were prospectively collected for up to 30 months after HCT using a standardized data collection tool...
2017: Open Forum Infectious Diseases
Snigdha Vallabhaneni, Kaitlin Benedict, Gordana Derado, Rajal K Mody
BACKGROUND: Invasive aspergillosis (IA) and mucormycosis contribute to substantial mortality, especially among immunocompromised persons, including those with hematopoietic stem cell transplant (HSCT), hematologic malignancy (HM), and solid organ transplant (SOT). METHODS: Using International Classification of Diseases, Ninth Revision codes available in the National Inpatient Sample, a hospital discharge database, we estimated IA-related hospitalizations (IA-RH), mucormycosis-RH (M-RH), HSCT-RH, HM-RH, and SOT-RH during 2000-2013...
2017: Open Forum Infectious Diseases
Jeremy A W Gold, Gordana Derado, Rajal K Mody, Kaitlin Benedict
To determine frequency and risk for sporotrichosis-associated hospitalizations, we analyzed the US 2000-2013 National (Nationwide) Inpatient Sample. An estimated 1,471 hospitalizations occurred (average annual rate 0.35/1 million persons). Hospitalizations were associated with HIV/AIDS, immune-mediated inflammatory diseases, and chronic obstructive pulmonary disease. Although rare, severe sporotrichosis should be considered for at-risk patients.
October 2016: Emerging Infectious Diseases
Kaitlin Benedict, Tom M Chiller, Rajal K Mody
Fungi are an integral part of the natural environment and, therefore, play many roles in relation to food: some fungi are used in food production, some are food sources themselves, and some are agents of food spoilage. Some fungi that contaminate food can also be harmful to human health. The harmful but noninfectious health consequences of mycotoxins have been well-characterized, but the extent to which fungi in food pose a risk for invasive infections is unknown. We conducted a literature review to identify cases of invasive fungal infections (IFIs) believed to have resulted from ingestion or inhalation of food, beverages, or dietary supplements (excluding Saccharomyces infections)...
July 2016: Foodborne Pathogens and Disease
Kaitlin Benedict, Anne E Purfield, Janet Mohle-Boetani, Charlotte Wheeler, Benjamin J Park
Coccidioidomycosis (Valley fever) is a major cause of illness in inmates in some California prisons. This article discusses an investigation conducted at two prisons to describe potential environmental exposures. The study did not identify modifiable risk factors; limiting the type or duration of outdoor activity in these prisons may not decrease coccidioidomycosis morbidity.
April 2016: Journal of Correctional Health Care
Kaitlin Benedict, Gordana Derado, Rajal K Mody
We examined trends in histoplasmosis-associated hospitalizations in the United States using the 2001-2012 National (Nationwide) Inpatient Sample. An estimated 50 778 hospitalizations occurred, with significant increases in hospitalizations overall and in the proportion of hospitalizations associated with transplant, diabetes, and autoimmune conditions often treated with biologic therapies; therefore, histoplasmosis remains an important opportunistic infection.
January 2016: Open Forum Infectious Diseases
Kaitlin Benedict, Rajal K Mody
Histoplasmosis has been described as the most common endemic mycosis in the United States. However, histoplasmosis is not nationally notifiable. Its presumed geographic distribution is largely derived from skin test surveys performed during the 1940s, and information about its local features comes primarily from outbreak investigations. We conducted a literature review to assess epidemiologic features of histoplasmosis outbreaks in the United States. During 1938-2013, a total of 105 outbreaks involving 2,850 cases were reported in 26 states and the territory of Puerto Rico...
March 2016: Emerging Infectious Diseases
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