Thais Dias Midega, Renato Carneiro de Freitas Chaves, Carolina Ashihara, Roger Monteiro Alencar, Verônica Neves Fialho Queiroz, Giovana Roberta Zelezoglo, Luiz Carlos da Silva Vilanova, Guilherme Benfatti Olivato, Ricardo Luiz Cordioli, Bruno de Arruda Bravim, Thiago Domingos Corrêa
Ketamine is unique among anesthetics and analgesics. The drug is a rapid-acting general anesthetic that produces an anesthetic state characterized by profound analgesia, preserved pharyngeal-laryngeal reflexes, normal or slightly enhanced skeletal muscle tone, cardiovascular and respiratory stimulation, and occasionally a transient and minimal respiratory depression. Research has demonstrated the efficacy of its use on anesthesia, pain, palliative care, and intensive care. Recently, it has been used for postoperative and chronic pain, as an adjunct in psychotherapy, as a treatment for depression and posttraumatic stress disorder, as a procedural sedative, and as a treatment for respiratory and/or neurologic clinical conditions...
2022: Revista Brasileira de Terapia Intensiva